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 The CNRU Mass Spectrometry Core offers Proteomics and Metabolomics workshops.
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Utility of Amino Acid Analysis in ResearchThe CNRU Mass Spectrometry Core Facility offers assistance in methods development and mass spectrometry analysis to help researchers study lipid metabolism using stable isotope methods. The human body utilizes stored triglycerides and releases glycerol and fatty acids from fat cells. Normally, lipids constitute more then 80% of stored fuel in the body. Stored triglyceride comes primarily from dietary fat. Fatty acids are important as energy substrates, use of stable isotopes as a tool can quantitate the rate of appearance of these substrates and can help understand the metabolic pathways and increase understanding of fat metabolism. Labeled glycerol enrichment in plasma can be used to measure whole body lipolysis and glucogenesis, and infusion of a glycerol tracer using microdialysis may be used to measure rates of lipolysis in adipose tissue.LIPID METABOLISM APPLICATIONS 
Fatty acid oxidation / fatty acid turnover
Glycerol kinetics to detect fatty acid triglyceride cycling
Endogenous synthesis of cholesterol
Rates of lipogenesis
Desaturation and elongation of fatty acids
Ketone body metabolism
Cholesterol absorption
Related Links Intracellular And Extracellular Recycling Fatty Acid Turnover Glycerol Turnover Fatty Acid Oxidation |
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