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Research Interest:
The Reyland lab is interested in protein kinase C delta (PKCδ) mediated regulation of apoptosis. PKCδ functions in signal transduction pathways by phosphorylating key cellular proteins involved in the apoptosis. We have shown that this phosphorylation is essential for genotoxin-induced apoptosis in the salivary gland. My thesis project focuses on the role of PKCδ during mammary gland development. In vivo studies include whole mount mammary gland analysis from PKCδ WT and KO mice, while in vitro studies utilize primary 3D culture. General Interests: Publications
Haas CS, Amin MA, Allen BB, Ruth JH, Haines GK 3rd, Woods JM, Koch AE. Inhibition of angiogenesis by interleukin-4 gene therapy in rat adjuvant-induced arthritis. Arthritis Rheum. 2006 Jul 25;54(8):2402-2414 PMID: 16869003 Haas CS, Amin MA, Ruth JH, Allen BL, Ahmed S, Pakozdi A, Woods JM, Shahrara S, Koch AE. In vivo inhibition of angiogenesis by interleukin-13 gene therapy in a rat model of rheumatoid arthritis. Arthritis Rheum. 2007 Aug;56(8):2535-48. PMID: 17665443 |
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