UC Denver - Anschutz Medical Campus: Cell Biology, Stem Cells and Development Graduate Program
Research in the Koch Lab The University of Colorado
   Cell Biology, Stem Cells and Development Graduate Program
  • Irene Choi
  • Research Statement
  • Publications
Irene Choi
Education:
Michigan State University
B.S. in Animal Science, 2003
Honors and Awards:
  • University of Colorado Graduate Fellowship, 2003
  • University of Colorado Diversity Fellowship, 2003

  • Thesis Advisor: Dennis Roop
    Charles C. Gates Regenerative Medicine and Stem Cell Biology
    UC Denver Anschutz Medical Campus
    Mail Stop #8320
    12801 East 17th Ave
    Aurora, CO 80045
    Laboratory Phone: 303-724-4563
    Email: Irene.Choi@ucdenver.edu
    Research Interest:

    I am fascinated by the signaling events inducing cell differentiation and organogenesis during embryonic development. I am particularly interested in the effects of exposure to environmental contaminants during development, such as subtle genetic changes that predispose the individual to diseases such as cancer.

    My first rotation was in the lab of Dr. Kristin Artinger, who is interested in the development of the early spinal cord, including the development of Rohan-Beard neurons. I looked at the interactions between the ectoderm and neural plate in the Xenopus embryo in the formation of these neurons, and found that bone morphogenic protein-4 may have a role in the induction of Rohon-Beard neurons.

    My current rotation is in the lab of Dr. Trevor Williams, whose research is focused on the AP-2 family of transcription factors. My project will involve identifying the expression pattern of AP-2a and looking for morphological changes in several mutant strains of mice.

    General Interests:
    I enjoy horsebackriding, painting/drawing, hiking, literature/fine arts, playing piano/guitar, playing outside in the sun and snow, and teaching my cat tricks.

    Publications

    Hernandez-Lagunas L, Choi IF, Kaji T, Simpson P, Hershey C, Zhou Y, Zon L, Mercola M, Artinger KB. Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Dev Biol 2005 Feb 15;278(2):347-57.

    Latest Publications in PubMed