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Cell biology is a dynamic discipline that combines the interests
and methods of a wide variety of scientific fields. Studies of cell
function are central to modern biological research as they focus
upon investigating the basic structural and functional unit of life:
the cell. By applying a wide range of experimental approaches to
the study of cellular processes, including biochemical and physical
analysis of molecules and cells in culture, and morphological methods,
cell biologist have made major discoveries that have had a dramatic
impact on human health. This key link between fundamental studies
of cell function and their relevance to disease is highlighted by
the work of the Cell Biology Faculty within the Graduate
Program in Cell Biology, Stem Cells and Development. Ongoing studies in
the areas of membrane trafficking, membrane dynamics, cell signaling,
motility, organelle composition and function, studies of the cytoskeleton
and extracellular matrix provide important insights and information
that is ultimately crucial for developing effective treatments for
cancer, heart disease, AIDS, and a host of other diseases that disrupt
normal cell function.
Cell Biology Faculty
| Name |
Research Interests |
| James
Crapo |
Molecular regulation of superoxide
dismutases in lung biology |
| Brian
Doctor |
Molecular interactions of
actin cytoskeleton and membranes in mammalian hepatobiliary
system |
| Joan
Hooper |
Cell determination, developmental
patterning and hedgehog signaling in drosophila |
| Kathryn
Howell |
Structure/function of the
Golgi complex using mass spectrometry, proteomics, functional
assays, and high resolution 3D structure |
| John
Hutton |
Secretory granule biogenesis
and exocytosis in the endocrine pancreas: role in human diabetes |
| Peter Koch |
Cell adhesion molecules in embryonic development and diseases |
| Karl
Pfenninger |
Regulation of pseudopod attachment
in nerve growth cones/cancer cells |
| Rytis
Prekeris |
Molecular mechanisms regulating
the establishment and maintenance of cellular polarity in epithelial
cells and neurons |
| Mary
Reyland |
Role of protein kinase C signaling
in programmed cell death |
| Pepper Schedin |
Stromal-epithelial interactions in mammary gland development, carcinogenesis and breast cancer prevention |
| Claude
Selitrennikoff |
Mechanisms of fungal wall assembly;
development of antifungal therapy |
| Alexander
Sorkin |
Molecular basis of endocytosis
and trafficking of growth factor receptors |

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