All animals begin life as a single cell, the result of a fusion
between sperm and egg. Through a staggering multitude of molecular,
cellular and tissue level events, a properly organized, multicellular
embryo is formed. In the last decade, our understanding of many
of these processes has expanded dramatically due to the advent of
cellular, molecular biological and genetic approaches. Intriguingly,
many of these processes first recognized in developmental contexts
have also been implicated in human disease. These types of fundamental
studies form the core of cutting edge research in Developmental
Biology by faculty of the Cell Biology, Stem Cells and Development Graduate Program at the University of Colorado Health
Sciences Center.
| Name |
Research Interests |
| Kristin
Artinger |
Molecular, genetic and developmental
mechanisms involved in the patterning of the early spinal cord
(neural plate) during vertebrate embryogenesis |
| Linda
Barlow |
Developmental neurobiology;
patterning and formation of sensory organs |
| Neil Box |
Mouse modeling of ribosomal protein loss |
| Steve
Britt |
Visual system development
and function using molecular/genetic approaches in Drosophila
|
| John
Caldwell |
Functional regulation of
ion channels in plasma membranes and Golgi membranes using electrophysiology
and molecular biology |
| David Clouthier |
Signaling pathways regulating craniofacial and cardiovascular development |
| Thomas
Evans |
Molecular and cellular mechanisms
of early embryonic development in C. elegans using genetic
and biochemical approaches |
| Thomas
Finger |
Development and organization
of taste and smell |
| Eva Grayck |
Hypoxia and pulmonary hypertension |
| Joan
Hooper |
Cell determination, developmental
patterning and hedgehog signaling in drosophila |
| Peter Koch |
Cell adhesion molecules in embryonic development and diseases |
| Maranke Koster |
Signaling pathways that control epidermal development and differentiation |
| Susan Majka |
Mesenchymal stem cells in pulmonary hypertension |
| Margaret
Neville |
Mammary gland biology and
the molecular switch between pregnancy and lactation |
| Lee Niswander |
Genetic mechanisms of limb, lung, and neural development |
| Karl
Pfenninger |
Regulation of pseudopod attachment
in nerve growth cones/cancer cells |
| Dennis Roop |
Skin development and disease |
| Trevor
Williams |
Transcriptional regulation
of mouse embryonic development and the role of transcription
factors in mammary gland development and breast cancer |
| Virginia Winn |
Human Placental Development,
Preeclampsia Pathogenesis |
