University of Colorado Health Sciences Center

Clinical Science

Course Book

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CLSC 6040 Introduction to Database and Web Design Programming Summer/Winter Inter-Sessions 1.0 cr.
J. Huggins – 399-8020 X3096
Min:1/Max:23

This course will provide the student with hands-on training for designing and creating both a database and a Website (and then bringing the two together) page for research project team use. The course will use MS Access to design a relational database that can be attached to a Web-base interface. Database design will primarily focus on tables, relationships and queries. Website design will be based on building pages that are standards-based and Section 508 accessible. A brief introduction connecting a database to the Website will be completed. For students without prior programming experience, this introductory class is a general pre-requisite to all other health information technology classes.

CLSC 6060 Systems Analysis and Design Fall/Spring Semesters 3.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:10

Offered as a collaborative offering with UCD, this course emphasizes information requirements analysis, logical system specification, and detailed system design. Topics include structured system development methodologies, prototyping, file design, systems architecture, system testing and software design strategies. Students will normally use a case tool to develop system specifications.

CLSC 6080 Database Management Systems Fall/Spring Semesters 3.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:10

Offered as a collaborative offering with UCD, this course focuses on the development and management of database systems to support business operations. Important subjects include semantic data modeling, normalization, SQL, fourth generation languages, and client-server database applications.

CLSC 6120 Data Communications Fall/Spring Semesters 3.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:10

Offered as a collaborative offering with UCD, this course introduces the basic concepts of data transmission, principles governing the design and administration of both wide and local area networks, and technical issues pertaining to client server computing and open system interconnection.

CLSC 6250 Introduction to Medical Informatics TBA 2.0 cr.
Dr. D. Lezotte – 315-6873. Prereq: A grad. degree in a clinical science or PRMD 6603 or Consent of Instructor.
Min:5/Max:24

Introductory course in medical informatics, exposing students to the entire spectrum of medical informatics applications and teaching skills to design and manage information systems that use data to promote improved quality and efficiency of clinical care.

CLSC 6300 Scientific Grant Review Process: GCRC Proposals Fall Semester 1.0 cr.
Dr. R. Eckel -- 315-8443. Prereq: BIOS 6601, 6602 (or BIOS 6611-6612), & CLSC 7500
Min:1/Max:3

Intended for second year students. Students will understand and participate in the process of scientific review of human subject research protocols submitted to the University of Colorado Health Science Center’s GCRCs (both Adult and Pediatric GCRCs).

CLSC 6500 Introduction to Pediatric Research Fall Semester 1.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:30

An introduction to the general field of clinical science with a focus on topics relevant to clinical research in the field of pediatrics. Designed for individuals who are interested in learning the fundamentals of how to prepare a scientific research proposal.

CLSC 6501 Introduction to Adult Medicine Research Fall Semester 1.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:23

An introduction to the general field of clinical science with a focus on topics relevant to clinical research in the field of adult medicine. Designed for individuals who are interested in learning the fundamentals of how to prepare a scientific research proposal.

CLSC 6502 Clinical Research Training Program Intensive Fall Semester 4.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:1/Max:70

CRTP Intensive-Part I (This two-part series must be taken as a whole to obtain any credit. Grades are assigned only after part II is completed).

CLSC 6503 Clinical Research Training Program Intensive Spring Semester 4.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:1/Max:70

CRTP Intensive-Part II (This two-part series must be taken as a whole to obtain any credit. Grades are assigned only after part II is completed.)

CLSC 6550 Applications of Biostatistics to Clinical Research Questions Fall Semester 1.0 cr.
Dr. M. O’Brien -- (303) 695-3305
Min:3/Max:30

An introduction to allow clinician-scientists to be critical consumers of the medical literature by improving their ability to discuss statistical issues about their own research and the research of others. A familiarity will be gained with many commonly used statistical methods, and statistical terms. Finally, students will improve their ability to determine when to seek assistance from a statistician.

CLSC 6650 Guided Research Tutorial Summer/Fall/Spring Semesters 1-3 cr.
Dr. L. Shroyer – 399-8020 X2678. Prereq: PRMD 6617, PRMD 6625, CLSC 7200
Min:1/Max:20

This course will expose the CLSC master’s degree students to a “hands-on” research project with which they are not currently familiar. Each student will be assigned to a mentored project and given a specific problem to address and/or a component of the project to complete. A project proposal or manuscript will be the basis for the student/mentor structured learning with an interim progress report and final project term paper to be submitted as the course requirements.

CLSC 6651 Guided Research Tutorial- Pediatric GCRC Research Spring Semester 2.0 cr.
Dr. F. Accurso – Prereq: CLSC 7300, CLSC 7500
Min:1/Max:2

Students perform Pediatric GCRC research projects during rotations under the direction of Pediatric GCRC faculty member(s).

CLSC 6652 Guided Research Tutorial- Adult GCRC Research Spring Semester 2.0 cr.
Dr. M. Garrity – Prereq: CLSC 7300, CLSC 7500>
Min:1/Max:2

Students perform Adult GCRC research projects during rotations under the direction of Pediatric GCRC faculty member(s).

CLSC 6653 Key Concepts in Neurodevelopmental Disabilities I Fall Semester 3.0 cr.
M. J. Rapport – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent)
Min:5Max:16

This course represents part I of a two part interdisciplinary course series focused on systems, options for diagnosis and assessment, as well as alternatives for service provision related to children, youth, and young adults with neurodevelopmental and related disabilities and their families to address this population’s special health care needs.

CLSC 6654 Key Concepts in Neurodevelopmental Disabilities II Spring Semester 3.0 cr.
M. J. Rapport – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent) and completion of CLSC 6653
Min:5/Max:16

This course represents part II of a two part interdisciplinary course series focused on systems, options for diagnosis and assessment, as well as alternatives for service provision related to children, youth, and young adults with neurodevelopmental and related disabilities and their families to address this population’s special health care needs.

CLSC 6657 Cultural Factors in Healthcare Summer/Fall/Spring Semesters 1.0 cr.
Dr. S. Manson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent)
Min:1/Max:Unlimited

This online course will introduce the subject of cultural and social determinants of maternal and child health in the present society, including world views on health perspectives (wellness versus illness), and address the impact of emerging demographic changes on systems of care. Participatory exercises will assist in understanding one’s own ethnic identity to better understand others, assessing regional and national demographic changes and their implications for practice, and cultural competence skill building.

CLSC 6658 An Interdisciplinary Approach to Promoting Early Parent Child Relationships- Part 1 Fall Semester 3.0 cr.
Dr. C. Robinson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent)
Min:1/Max:25

This is Part 1 of a two part course series that will examine the theory and research relevant to the assessment of early parent-child relationships as well as the clinical application for interventions across disciplines that are intended to promote and improve child health outcomes.

CLSC 6659 An Interdisciplinary Approach to Promoting Early Parent Child Relationships- Part 2 Spring Semester 3.0 cr.
Dr. C. Robinson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent) and completion of CLSC 6658
Min:1/Max:25

This is Part 2 of a two part course that will examine the research relevant to the assessment of early parent-child relationships, identify intervention strategies by analyzing observational findings, as well as evaluate the effectiveness of interventions across disciplines that are intended to promote and improve child health outcomes.

CLSC 6661 Leadership Dialogues I Fall Semester 1.0 cr.
Dr. C. Robinson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent)
Min:1/Max:15

This interdisciplinary leadership course focuses on leadership strategies needed for providing family centered, culturally competent, community-based services for children with special needs and their families.

CLSC 6662 Leadership Dialogues II Spring Semester 1.0 cr.
Dr. C. Robinson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent) and completion of CLSC 6661
Min:1/Max:15

This interdisciplinary leadership course focuses on becoming change agents to better provide family-centered, culturally competent, community-based services for children with special needs and their families.

CLSC 6666 Transdisciplinary Model of Early Intervention Service Delivery Fall Semester 3.0 cr.
Dr. C. Robinson – 864-5267. Prereq: A degree in health care profession or related field (or instructor consent)
Min:1/Max:25

This course provides instruction about the ENRICH model of community-based, family-driven, transdisciplinary service delivery. The course will target service coordination and collaboration throughout Part C supports and services, best practice implementation of intervention strategies, and techniques for transferring out of Part C. There is an optional practicum (CLSC 6830) that is available for an additional 3 credits. This lab provides hands-on experiences that enhance the coursework.

CLSC 6699 Research in Clinical Science for Masters Students Summer/Fall/Spring Semesters 1-4 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:1/Max:5

Research in the Clinical Science field that is planned to have direct relevance to a Masters Thesis Project where a student is working under a mentor faculty member’s guidance and direction. Class work may also be associated with preparing for the written component of the master’s final exam.

CLSC 6700 Evidence Based Medicine/Health Care Spring Semester 2.0 cr.
Dr. B. Brimhall – 372-0324
Min:1/Max:15

This course is designed to provide a basic introduction to the quickly evolving field of clinical science related to evidence based medicine and health care. Students will learn how to critically appraise the literature, evaluate diagnostic test performance, evaluate alternative therapies, use/design clinical pathways, and implement evidenced based medicine findings in their own clinical practice settings.

CLSC 6800 Introduction to Health Information Technology Spring Semester 3.0 cr.
Dr. D. Lezotte – 315-6873.
Min:3/Max:10

This course is intended as an overview to the dynamic environment of healthcare informatics. The goal of the course is to prepare healthcare professionals to better utilize and manage the emerging communication technologies.

CLSC 6820 Fundamentals of Health Information Technology Management Fall Semester 3.0 cr.
Dr. D. Lezotte – 315-6873.
Min:3/Max:10

This course will provide an introduction to the management of information technology in healthcare. A description of information processing, the origin, content and evolution of healthcare information systems and the methodologies deployed to acquire and manage information requirements will be discussed.

CLSC 6830 Practicum in Developmental Disabilities I Fall Semester 3.0 cr.
M. J. Rapport – 864-5267. Prereq: Instructor Consent
Min:1/Max:20

Practicum in developmental disabilities individually designed to give students and post graduates observational experiences in clinical, teaching, or research service settings and systems for persons with developmental disabilities of all ages.

CLSC 6831 Practicum in Developmental Disabilities II Spring Semester 3.0 cr.
M. J. Rapport – 864-5267. Prereq: Instructor Consent and completion of CLSC 6830
Min:1/Max:20

Practicum in developmental disabilities individually designed to give students and post graduates hands-on experiences in clinical, teaching, or research service settings and systems for persons with developmental disabilities of all ages.

CLSC 6890 Introduction to Telehealth/Telemedicine Summer Semester 2.0 cr.
Dr. J. Grigsby – (303) 756-8350.
Min:3/Max:23

This course will examine different Telemedicine/Telehealth options currently available. A primary goal will be for students to evaluate how clinical outcomes and health care education (e.g., patient education and health care provider education) can be improved using new technologies.

CLSC 6950 Masters Thesis Summer/Fall/Spring Semesters 1-4 cr.
Faculty- 399-8020 X3716

CLSC 7050 Designing and Implementing Clinical Disease Management Programs Spring Semester 2.0 cr.
Dr. D. Tinkelman - 398-1519. Prereq: None, however BIOS 6601,6602 or BIOS 6611,6612, 6613 suggested.
Min:1/Max:16

This course is designed to introduce participants to the new and broadening field of disease management. Students will learn about the positive and negative aspects of varied approaches in the field. The economic and clinical aspects of disease management will be discussed

CLSC 7101 Grant Writing I Spring Semester 1.0 cr.
Dr. J. Crapo – 398-1657. Prereqs: BIOS 6601-, PRMD 6626 or BIOS 6648, and CLSC7150 or CLSC 7151.
Min:3/Max:6

This course will prepare students for subsequent grant submission. Strategies for preparation (including hypothesis generation, experimental design, statistical considerations, and potential problems) will be discussed. At the end of this class, a grant submission will normally occur before a grade is assigned

CLSC 7102 Grant Writing II Spring Semester 1.0 cr.
Dr. J. Crapo – 398-1657. Prereq: CLSC 7101.
Min:3/Max:6

Continuation of CLSC 7101. This course will prepare students for subsequent grant submission. Strategies for preparation (including hypothesis generation, experimental design, statistical considerations, and potential problems) will be discussed. At the end of the course, a KO8, R23, or equivalent grant application will be completed for submission.

CLSC 7150 Ethics and Regulation in Human Subjects Review Spring Semester 1.0 cr.
Dr. A. Prochazka - 399-8020 X2144.
Min:1/Max:10

This course will provide an overview of the field of ethics in clinical research. It is designed for Clinical Science students who will be conducting research involving human subjects. Students will learn the historical background, current regulations, and IRB requirements related to human subjects protection issues. This course requires attendance at IRB sessions for CLSC Ph.D. and Certificate students enrolled.

CLSC 7151 Lectures in Ethics and Regulation in Human Subjects Review Spring Semester 1.0 cr.
Dr. A. Prochazka - 399-8020 X2144.
Min:3/Max:20

This course will provide an overview of the field of ethics in clinical research. It is designed for non-Clinical Science degree students and investigators who will be conducting research involving human subjects. Topics include the historical background, current regulations, and IRB requirements.

CLSC 7155 Advanced Bioethics Spring Semester 1.0 cr.
Dr. A. Prochazka – 303-399-8020 X2144. Prereq: CLSC 7150 or CLSC 7151; or PHSC 7339 or COMIRB 101
Instructor’s consent

This course will provide an in-depth understanding of advanced bioethics – where the frontiers for ethical clinical decision-making currently exist – and also provide a broad-based overview of all aspects of responsible conduct of research according to NIH standards.

CLSC 7200 Clinical Outcomes Assessment Spring Semester 2.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:3/Max:23

This course provides an overview of the field of clinical outcomes assessment. It will prepare students to identify the patient risk factors which may influence outcomes and to select a set of outcomes appropriate to use in a given situation based on critical appraisal of the literature in context of the research project’s goals and objectives. Students also will learn how to develop a project implementation strategy.

CLSC 7300 Scientific Grant Review Process: GCRC Proposals Fall Semester 1.0 cr.
Dr. R. Eckel – 315-8443. Prereq: BIOS 6601, 6602 (or BIOS 6611, 6612), and CLSC 7500.
Min:1/Max:3-6

Intended for second year students. Students will understand and participate in the process of scientific review of human subject research protocols submitted to the University of Colorado Health Science Center’s GCRCs (both Adult and Pediatric GCRCs).

CLSC 7400 Theory and Application of Techniques for the Study of Human Metabolism In Vivo Fall Semester 2.0 cr.
Dr. T. Horton – 399-8020 X3716. Prereq: (CLSC 7150/7151) and [(CLSC 6500/6501) or PRMD 6626 or BIOS 6648]
Min:3/Max:15

This advanced clinical investigation course will critically review lab-based techniques and experimental approaches used to study nutrient metabolism in vivo. Students will learn the theory, appropriate application and limitations of these technique/approaches

CLSC 7450 Biopharmaceutics and Applied Pharmacokinetics Summer Semester 2.0 cr.
Dr. T. Henthorn - 303-372-6351 Prereq: BIOS 6602
Min:3/Max:15

This advanced pharmacokinetics course will provide working knowledge of drug administration, distribution, metabolism and excretion as well as provide practical clinical working examples of pharmacokinetics (drug clearance and distribution).

CLSC 7500 Practical Application of Molecular and Cell Biology Techniques for the Clinical Investigator Summer Semester 3.0 cr.
Dr. A. Bradford – 315-4146.>
Min 8:/Max:60

Designed to teach clinical investigators basic molecular and cellular biology techniques. Format will be hands on with lectures designed to illustrate significance and clinical application of techniques. Weekly special topics lectures will cover cutting-edge technologies and their application.

CLSC 7650 Guided Research Tutorial - General Summer/Fall/Spring Semesters 1-3 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:1/Max:20

Students perform research projects during rotations under the direction of a mentor. Required of graduate students in the Clinical Sciences Ph.D. program.

CLSC 7651 Guided Research Tutorial – Pediatric GCRC Research Spring Semester 2.0 cr.
Dr. F. Accurso – 837-2522. Prereq: CLSC 7300 and CLSC 7500
Min:1/Max:2

Students perform Pediatric GCRC research projects during rotations under the direction of Pediatric GCRC faculty member(s).

CLSC 7652 Guided Research Tutorial – Adult GCRC Research Fall/Spring Semesters 2.0 cr.
Dr. M. Garrity – 315-7361. Prereq: CLSC 7300 and CLSC 7500
Min:1/Max:2

Students perform Adult GCRC research projects during rotations under the direction of an Adult GCRC faculty member(s).

CLSC 7700 Evidence Based Medicine/Health Care Spring Semester 2.0 cr.
Dr. B. Brimhall – 372-0324
Min:1/Max:15

This course is designed to provide a basic introduction to the quickly evolving field of clinical science related to evidence based medicine and health care. Doctoral students will learn how to critically appraise the literature, evaluate diagnostic test performance, evaluate alternative therapies, use/design clinical pathways, and implement evidenced based medicine findings in their own clinical practice settings. Doctoral students will also write a manuscript to be submitted related to a critical appraisal of the literature on a topic of their choice.

CLSC 7890 Research in Clinical Sciences for Doctoral Students Summer/Fall/Spring Semesters 1.0–5.0 cr.
Dr. L. Shroyer – 399-8020 X2678.
Min:1/Max:5

Research in clinical science field that is planned to have direct relevance to a Ph.D. dissertation project where the doctoral student is working under mentor faculty member’s guidance and direction. Class work may also be associated with preparing for the written component of the Ph.D. comprehensive exam and/or for the oral comprehensive exam component.

CLSC 8990 Doctoral Thesis Summer/Fall/Spring Semesters 1-10 cr. (Note: Graduate School approval required for more than 10 credits - contact Dr. Laurie Shroyer for authorization.)
Faculty
Min:1/Max:20