CLSC 7500

Practical Application of Molecular and Cell Biology Techniques for the Clinical Investigator

Bradford and Tentler

Summer

3

This course is designed to teach clinical investigators basic molecular and cellular biology techniques. The format will be hands-on lectures designed to illustrate significance and clinical application of techniques. Weekly special topics lectures will cover cutting edge technologies and their application.

CLSC 6300

Scientific Grant Review Process: GCRC Proposals

Eckel, Sokol

Fall

1

Intended for second year students. Students will understand and participate in the process of scientific review of human subject research protocols submitted to the UCD GCRCs (both Adult and Pediatric GCRC).

CLSC 6651

GCRC Core Laboratory: Pediatrics

Accurso

Spring

1-2

This course is designed to provide students with an understanding of laboratory methodologies as they relate to the design and execution of clinical research protocols.  

CLSC 6652

GCRC Core Laboratory: Adult

Garrity

Spring

1-2

This course is designed to provide students with an understanding of laboratory methodologies as they relate to the design and execution of clinical research protocols.  

CLSC 6650

Guided Research Tutorial

Shroyer with Assigned Mentor

All

1-3

Students will perform research projects during rotations under the direction of a mentor writing a manuscript, book chapter, or gathering pilot data for a peer-reviewed grant application. A minimum of one rotation through this course is required. Individuals wishing to gain exposure to additional research areas may take this course three times for a total of nine credit hours.

BIOS 6601

Biostatistics Methods I

Faculty

Fall/Spring

4

This course designed primarily to provide graduate students with a practical knowledge of the quantitative methods most frequently used in applied research. This semester deals with elementary probability and parametric methods for handling one- and two-sample estimation and testing problems with continuous data. The content includes the chi-squared statistics, linear and logistic regression, parametric and nonparametric correlation, an introduction to analysis of variance, life table methodology, and miscellaneous topicsThis course also includes an introduction to computer statistical packages.

BIOS 6611

Computer Oriented Statistical Methods I

Faculty

Fall

3

This is the first of an accelerated three Semester sequence designed primarily to equip graduate students with a practical knowledge of the quantitative methods most frequently used in medical research. This Semester deals with elementary probability, and parametric and nonparametric methods for handling one and two sample estimationemphasizing linear and nonlinear regression differential calculus, matrix algebra, and the SAS statistical package. This course is a prerequisite for BIOS 6612.

CLSC 6550

Applied Biostatistics

O'Brien

Fall/Spring

1

An introduction to allow clinician-scientists to be critical consumers of the medical literature by improving their ability to
discuss statistical issues about their own research and the research of others. A familiarity will be gained with many commonly used statistical methods, and statistical terms. Finally, students will improve their ability to determine when to seek assistance from a statistician.

BIOS 6648

Design of Clinical Trials and Experiments

Kittelson

Spring

2

This course covers the theory and methodology of design techniques applied to medical research. Topics include sample size determination, blocking, randomization, and replication.

PRMD 6626

Research Methods in Community Health

Lezotte

Spring

3

With a follow-up of more advanced statistical techniques commonly used in observational study designs, this research methods topics include: clinical trials, medical care evaluation, and survey research. Lectures and discussions cover problem statement and hypothesis formulation, study design, data collection and analysis. Students will gain practical experience through analysis of large data sets available at state agencies.

CLSC 6501

Introduction to Adult Medicine Research

Shroyer

Fall

1

An introduction to the general field of clinical science with a focus on topics relevant to clinical research in the field of
adult medicine. Designed for individuals who are interested in learning the fundamentals of how to prepare a scientific research proposal.

CLSC 6500

Introduction to Pediatric Research Methods

Shroyer

Fall

An introduction to the general field of clinical science with a focus on topics relevant to clinical research in the field of
pediatrics. Designed for individuals who are interested in learning the fundamentals of how to prepare a scientific research proposal.

CLSC 6040

Introduction to Database and Web Design Programming

Huggins

Intersessions

Pre-Fall
Pre-Spring

1

This course will provide the student with hands-on training for designing and creating both a database and a Website (and then bringing the two together) page for research project team use. The course will use MS Access to design a relational database that can be attached to a Web-based interface. Database design will primarily focus on tables, relationships and queries. Website design will utilize Macromedia Dreamweaver. Website design will be based on building pages that are standards-based and Section 508 accessible. A brief introduction connecting a database to the Website will be completed. For students without prior programming experience, this introductory class is a general pre-requisite to all other health information technology classes for students without database programming or web design experience.

CLSC 7150

Ethics and Regulation in Human Subjects Research

Prochazka, Shroyer, Milgrom

Fall/Spring

1

This course will provide an overview of the field of ethics in clinical research. It is designed for investigators who will be conducting research on human subjects. Students will learn the historical background, current regulations, and IRB requirements related to human subjects protection issues. Students will attend at least two National Jewish Center IRB sessions to learn how to become IRB members.

CLSC 7155

Advanced Bioethics

Yarborough, Prochazka, Shroyer, and Fennessey

Intersession
Pre-Spring

1

This course will provide an in-depth understanding of advanced bioethics – where the frontiers for ethical clinical decision-making currently exist related to informed clinical decisions, as well as also provide a broad-based overview of all aspects of responsible conduct of research according to NIH standards.

CLSC 7101

Grant Writing I

Crapo and Shroyer

Spring

1

This course will prepare students for subsequent grant submission. Strategies for preparation (including hypothesis generation, experimental design, statistical considerations and potential problems) will be discussed. By course end, a fellowship grant application (or equivalent) will be completed.

CLSC 6700

Evidence Based Medicine

Brimhall, Shroyer

Spring

2

This course is designed to provide a basic introduction to the quickly evolving field of clinical science related to evidence based medicine and health care. Students will learn how to critically appraise the literature, evaluate diagnostic test performance, evaluate alternative therapies, use/design clinical pathways, and implement evidenced based medicine findings in their own clinical practice settings.

PRMD 6630

Epidemiology

Hamman

Fall

4

This course offers an introduction to:  1) the approaches and methods used in describing the natural history of disease in the community and for locating clues to the causes of disease, and 2) analytical epidemiology (study design, bias, confounding and measures of excess risk) used in the study of disease etiology and the critical review of the medical literature. Lectures/discussions are supplemented with problem-solving exercises. For four credits, a term paper is required in addition to other work.