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Spring 1998

The University of Colorado Denver

Volume 1, Number 2

Geriatrics Center of
Excellence News

We are pleased to announce the recipients of the first Center of Excellence stipends and grants. We had many excellent applications for these funds and would like to thank all who applied for their interest in geriatrics.

The Assistant Professor Stipend was awarded to Dr. Marie Johnson who is in the Division of General Internal Medicine at Denver Health Medical Center. Marie is completing the Geriatric Medicine Fellowship at the University of Colorado this year and will use the stipend to fund 50% of her time over the next three years to conduct


The Assistant Professor
Stipend was awarded to Dr.
Marie Johnson.


her project entitled, "The Influence of Physicians' Attitudes and Behaviors on Patient Outcomes at the End of Life."

She will also enroll in the Certificate of Public Health Program in the Department of Preventive Medicine and Biometrics, and play a lead role in program development for geriatrics at Denver Health. Marie has demonstrated a strong interest in geriatrics throughout her medical career, first at the University of California San Francisco, then as a faculty member at Denver Health Medical Center. She plans to build on her stipend activities to continue in academic geriatrics as a clinician, teacher, and researcher.

The Mid-career Stipend was awarded to Dr. Thomas Whitehill, Assistant Professor of Vascular Surgery. His research will focus on outcomes of patients receiving surgery for abdominal aortic aneurysms and he will obtain further clinical training in geriatric medicine. Dr.

Whitehill has demonstrated a strong interest in geriatric medicine throughout his surgical career, and over 90% of his patients are 65 years of age or older.


The Mid-Career Stipend was
awarded to
Dr. Thomas Whitehill.


On the faculty at UCD for the past four and one-half years, he has been productive in basic science research relating to the etiology and progression of atherosclerosis. We believe Tom Whitehill will be a major contributor to geriatric medicine in the Health Sciences Center as he develops his clinical research activities and greater clinical skills in geriatrics with which he plans to begin teaching surgical residents about geriatric care issues.

A grant was awarded to Dr. John Weil, Professor of Medicine and Director of the Cardiovascular Pulmonary Research Laboratory. His project entitled "L-Arginine Levels and Nitric Oxide Activity in the Elderly - Responses to Arginine and Vitamin Supplements" builds on preliminary findings from his lab that L-arginine levels decline with aging and could constitute a reversible contributor to development and progression of vascular dysfunction. They have found that multi-vitamins and possibly anti-oxidants increase L-arginine levels in young, healthy subjects.

Thus, this study involves expanding their work to focus on elderly persons and determining how L-arginine levels can be raised through vitamin supplementation. We are pleased that Dr. Weil and the distinguished research team from the Cardiovascular Research Lab including Drs. Lindenfield and Tyler will be contributors to the Center of Excellence.

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Focus: San Luis Valley
Health and Aging Study

This NIA-funded study, conducted by the Department of Preventive Medicine and Biometrics, focuses on disability and disease among aging Hispanic and non-Hispanic white (NHW) residents of two counties in southern Colorado. The San Luis Valley (SLV) Health and Aging Study, begun in 1992 with 5 years of funding, started with a 4-hour baseline clinic evaluation of 1433 Hispanic and NHW persons.

By 1997, a two-year follow-up assessment of this cohort was completed, with 83% returning. A 3-year, $1.1 million, competing continuation grant to conduct surveillance of the cohort and analyses from the existing data will begin in April 1998.


A central focus of the study is
to assess whether the rates
and risk factors for aging
related outcomes are the
same between Hispanic and
NHW elderly.


Specific Aims:

v To determine the prevalence of functional impairment, physical disability, need for assistance in activities of daily living (ADL), depression, and cognitive impairment by self-report and examination in a cohort of Hispanic and non-Hispanic white subjects in two counties in southern Colorado;

v To measure selected risk factors and disease endpoints in the cohort, including physical activity and nutritional intake, blood pressure, and co-morbid conditions;

v To determine the use of formal and

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