Dr. Shroyer is Board Certified in Anatomic and Clinical Pathology (1991), with subspecialty certification in Cytopathology (1995).  Research interests include the application of novel molecular markers as a diagnostic adjunct in the analysis of surgical pathology and cytopathology clinical specimens.  Dr. Shroyer’s research laboratory has extensive experience in the application of molecular assays, including HPV detection and telomerase analysis to clinical specimens.  His laboratory is nationally recognized for translational studies regarding the development and application of novel tumor markers in premalignant and malignant lesions of the female genital tract.

Publications:  (partial list from a total of 75 original manuscripts):

1. R. Lehner, E. Jarboe, R. Gianani, S. Lucia, J.A. McGregor, A.L. Shroyer, and K. R. Shroyer. Localization of inhibitor of apoptosis protein-survivin in normal transitional cell epithelium and in carcinoma. Appl. Immunohistochem. Molec. Morphol. 10:134-138, 2002.
2. R. Lehner, T. Enomoto, J.A. McGregor, A.L. Shroyer, and K. R. Shroyer. Quantitative analysis of telomerase hTERT mRNA and telomerase activity in endometrioid adenocarcinoma and in normal endometrium. Gynecol. Oncol. 84: 120-25, 2002.
3. R. Lehner, T. Enomoto, J.A. McGregor, A.L. Shroyer, B.R. Haugen, U. Pugazhenthi, and K. R. Shroyer. Correlation of survivin mRNA detection with histologic diagnosis in normal endometrium and endometrial carcinoma. Acta Obstetricia et Gynecologica Scandinavica 81: 162-7, 2002.
4. M. Frost, E.A. Jarboe, R. Gianani, L.C. Thompson, T. Enomoto, D. Uribe-Lopez, K. R. Shroyer. Immunohistochemical localization of survivin in benign cervical mucosa, cervical dysplasia, and invasive squamous cell carcinoma. Am. J. Clin. Path. 117: 738-44, 2002.
5. L. Bonds, P. Baker, C.J. Gupp, K. R. Shroyer. Analysis of Cdc6 expression in cervical neoplasia and carcinoma. Arch. Path. Lab. Med. 126: 1163-68, 2002.
6. T. Enomoto, H. Sun, K. R. Shroyer, K. Ozaki, M. Fujita, C. Kuragaki, Y. Ueda, R. Nakashima, G. Ueda, Y. Murata. Analysis of clonality and mutations of PTEN and the K-ras genes in endometrial hyperplasia. Diag Molec Path. 11: 204-11, 2002.
7. K. R. Shroyer. Immunohistochemical markers of cell immortality. Hum. Pathol. 33: 683-85, 2002.
8. E.A. Jarboe, K.-L. Liaw, C. Thompson, D. Heinz, P. Baker, J.A. McGregor, T. Dunn, J.E. Woods, and K. R. Shroyer. Analysis of Telomerase as a Diagnostic Biomarker of Cervical Dysplasia and Carcinoma. Oncogene, 21: 664-673, 2002.
9. K. Trieb, R. Lehner, T. Stulnig, I. Sulzbacher, and K. R. Shroyer. Survivin expression in human osteosarcoma is a marker for survival. Eur. J. Surg. Oncol. 29: 379-82, 2003.
10. B.K. Kleinschmidt-DeMasters, D. Heinz, P.J. McCarthy, J.B. Bobak, K.O. Lillehei, and K. R. Shroyer. Survivin in glioblastomas: protein and mRNA expression and comparison with telomerase levels. Arch Pathol Lab Med. 127: 826-33, 2003.
11. J.E. Barrera, M. Miller, S. Said, B. Jafek, J. Campana, K. R. Shroyer. Detection of micrometastasis using immunohistochemistry of pancytokeratin in neck dissection specimens from patients with head and neck squamous cell cancer. Laryngoscope 113:892-6, 2003.
12. S. Prindiville, T. Byers, F.R. Hirsch, W.A. Franklin, Y.E. Miller, K.O. Vu, H.J. Wolf, A.E. Baron, K. R. Shroyer, C Zeng, T.C. Kennedy, and P.A. Bunn. Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction. In Press, Cancer Epidem., Biomarkers, Prevention.
13. J.H. Willman , D. Heinz, L.E. Golitz , K. R. Shroyer. p16 and pRb expression in Bowen's disease with correlation of HPV detection by PCR. In press, J. Cutaneous Path.
14. E.A. Jarboe, L.C. Thompson, D. Heinz, J.A. McGregor, K.R. Shroyer. Telomerase and HPV as Diagnostic Adjuncts for Cervical Dysplasia and Carcinoma. In press, Human Pathology.
15. Y. Ueda, T. Enomoto, T. Miyatake, K. Ozaki, T. Yoshizaki, H. Kanao, Y. Ueno, R. Nakashima, K. R. Shroyer, Y. Murata. Monoclonal expansion triggered by integration of high-risk type HPVs is an initial step for cervical carcinogenesis. In press, Laboratory Investigation.
16. R. Lehner, B. Tringler, A.L. Shroyer, and K. R. Shroyer. Immunohistochemical localization of survivin in serous tumors of the ovary. In press, Applied Immunohistochemistry and Molecular Morphology.