
Robert H. Allen
M.D.
Professor of Medicine
Co-Head Division of Hematology
Go To Full Curriculum Vitae
- Medical School:
- Washington University School of Medicine, St. Louis, Missouri
- Postgraduate training:
- 1966-1967 Intern in Medicine, Parkland Memorial Hospital, Dallas, Texas
1967-1969 Staff Associate, National Institute of Arthritis, Metabolism
and Digestive Diseases, Bethesda, Maryland
1969-1970 Senior Resident in Medicine, Barnes Hospital, St. Louis, Missouri
1970-1972 Fellow in Hematology/Oncology, Washington University School of
Medicine, St. Louis, Missouri
- When arrived at UCD:
- 1977
- Past and current professional positions:
- 1972-1975 Assistant Professor of Medicine, Washington University School of
Medicine, St. Louis, Missouri
1975-1977 Associate Professor of Medicine, Washington University School
of Medicine, St. Louis, Missouri
1977-Present Professor of Medicine, University of Colorado Denver, Denver, Colorado
1977-1998 Director, Division of Hematology, University of Colorado Denver, Denver, Colorado
1992-Present Cleo Meador and George Ryland Scott Professor of Hematology
Research,
University of Colorado Denver, Denver, Colorado
1998-Present Co-Director, Division of Hematology, University of Colorado Denver, Denver, Colorado
- Memberships and other information:
- American Society of Hematology
American Society of Biological Chemists
American Society for Clinical Investigation
Association of American Physicians
- Board Certification:
- Internal Medicine, 1974
Hematology, 1976
- Awards received:
- Alpha Omega Alpha
1974-1978 American Cancer Society Faculty Research Award
1986 MERIT Award, National Institute of Diabetes and Digestive and
Kidney
Diseases, NIH
1994 Chairman, FASEB Summer Research Conference on Folic Acid, Vitamin
B12
and One Carbon Metabolism, Copper Mountain, Colorado
- Major Scientific Interest:
- Absorption, transport and metabolic role of
cobalamin and cobalamin analogues.
- Major Clinical Interest:
- Diagnosis and clinical manifestations of cobalamin
and folate deficiencies.
- Representative Publications:
-
- Allen, Robert H., and Majerus, Philip W. Isolation of vitamin B12-binding
proteins using affinity chromatography. III. Purification and properties
of human plasma transcobalamin II. J Biol Chem 247:7709-7717, 1972.
- Kolhouse,
J. Fred, Kondo, Haruki, Allen, Nancy C., Podell, Elaine R. and Allen,
Robert H. Cobalamin analogues are present in human plasma and
can mask cobalamin deficiency because current radioisotope dilution assays
are
not specific for true cobalamin. New Engl J Med 299:785-792, 1978.
- Kondo,
Haruki, Kolhouse, J. Fred and Allen, Robert H. Presence of cobalamin
analogues in animal tissues. Proc. Natl. Acad. Sci. U. S. A.
77:817-821, 1980.
- Kovachy, Robin J., Copley, Shelley D. and Allen,
Robert H. Recognition, isolation, and characterization of rat liver
D-methylmalonyl coenzyme
A hydrolase. J Biol Chem 258:11415-11421, 1983.
- Stabler, Sally
P., Marcell, Paul D., Podell, Elaine R., Allen, Robert H., Savage,
David and Lindenbaum, John. Elevation of total
homocysteine in the serum of patients with cobalamin or folate deficiency
detected
by capillary gas chromatography-mass spectrometry. J Clin Invest
81:466-474,
1988.
- Lindenbaum, John, Healton, Edward B., Savage, David G,
Brust, John C.M., Garrett, Thomas J., Podell, Elaine R., Marcell, Paul
D., Stabler,
Sally
P. and Allen, Robert H. Neuropsychiatric disorders caused by
cobalamin deficiency in the absence of anemia or macrocytosis. New Engl
J
Med 318:1720-1728, 1988.
- Allen, Robert H., Stabler, Sally P.,
Savage, David G. and Lindenbaum, John. Metabolic abnormalities in cobalamin
(vitamin
B12) and folate
deficiency. FASEB J 7:1344-1353, 1993.
- Niyikiza, Clet, Baker,
Sharyn, Seitz, David E., Walling, Jackie M., Nelson, Katrina, Rusthoven,
James J., Stabler, Sally
P.,
Paoletti, Paolo,
Calvert, A. Hilary and Robert H. Allen. Homocysteine and
methylmalonic acid: Markers to predict and avoid toxicity from pemetrexed
therapy. Mol Cancer Ther 1:545-552, 2002.
- Wright, Clinton B., Paik, Myunghee C., Brown, Truman R., Stabler, Sally P., Allen,
Robert H., Sacco, Ralph L., DeCarli, Charles. Total homocysteine is associated with white
matter hyperintensity volume: the Northern Manhattan Study. Stroke 36:1207-11, 2005.