I'm working on host-pathogen interactions, specifically subversion of early innate immune responses by intracellular bacteria. Our lab uses Listeria monocytogenes as a model pathogen. I am interested in how bacterial virulence factors influence pathogen growth and the production of innate cytokines (specifically NK cell IFN-gamma), and which cell types and signaling molecules are involved in this process.
Awards/Publications:
NIAID/NIH Institutional Training Grant, pre-doctoral (2004-2007)
American Society for Microbiology Student Travel Grant (2007 ASM General Meeting)
Humann, J., Bjordahl, R., Andreasen, K., Lenz, L. L. 2007. Expression of the p60 autolysin enhances NK cell activation and is required for Listeria monocytogenes expansion in IFNγ-responsive mice. J Immunol. 178: 2407-2414.
Liu, S., Velez, M. G., Humann, J., Rowland, S., Conrad, F. J., Halverson, R., Torres, R. M., Pelanda, R. 2005. Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens. J Immunol. 175: 5067-5076.
Lab:Laurel Lenz Starting Year: 2004 e-mail:jessica.humann@uchsc.edu
Lab Phone: 303-398-1317 Undergrad: University of Puget Sound Home Town: Springville, CA Social Network/Website:
Jessica Humann
Department Website
Student Website
- Message Board
2007-2008 All rights reserved. University of Colorado Denver - Integrated Department of Immunology