Finkelstein, R.A., Vasil, M.L. and Holmes, R.K. Studies of toxinogenesis in Vibrio cholerae. I. Isolation of mutants with altered toxinogenicity. J. Infect. Dis. 129:117, 1974
Vasil, M.L., Holmes, R.K. and Finkelstein, R.A. Studies on toxinogenesis in Vibrio cholerae. II. An in vitro test for enterotoxin production. Infect. Immun. 9:195, 1974.
Holmes, R.K., Vasil, M.L. and Finkelstein, R.A. Studies on toxinogenesis inVibrio cholerae. III. Characterization of nontoxinogenic mutants in vitro and in experimental animals J. Clin. Invest. 55:551, 1975.
Vasil, M.L., Holmes, R.K. and Finkelstein, R.A. Conjugal transfer of a chromosomal gene determining production of enterotoxin in Vibrio cholerae. Science 187:849, 1975.
Finkelstein, R.A., LaRue, M.K., Vasil, M.L., Johnson, D. and Cho. G. Isolation and properties of heat-labile enterotoxin(s) from enterotoxigenic Escherichia coli (ETEC). J. Infect. Dis. (Suppl.) 133:S120, 1975.
Finkelstein, R.A., Vasil, M.L., Jones, J.R., Anderson, R.A. and Bernard, T. Clinical cholera caused by enterotoxigenic Escherichia coli. J. Clin. Microbiol. 3:382, 1976.
Vasil, M.L., Liu, P.V. and Iglewski, B.H. Characterization of a temperature-dependent inactivating factor of Pseudomonas aeruginosa exotoxin A. Infect. Immun. 13: 1436, 1976.
Vasil, M.L., Kabat, D. and Iglewski, B.H. Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa. Infect. Immun. 16:353, 1977.
Bjorn, M.J., Vasil, M.L., Sadoff, J.C. and Iglewski, B.H. Detection and expression of exotoxin produced by Pseudomonas species Infect. Immun.16:362, 1978
Iglewski, B.H., Bjorn, M.J. and Vasil, M.L. The influence of iron on the production of exotoxin A by Pseudomonas aeruginosa. Infect. Immun., 19:785, 1978.
Vasil, M.L. and Iglewski, B.H. Comparative toxicities of diphtherial and Pseudomonas toxin: Evidence for different cell receptors. J. Gen. Microbiol., 108:333, 1978.
Holmes, R.K., Baine, W.B. and Vasil, M.L. Quantitative measurements of cholera enterotoxin in cultures of toxinogenic wild type and nontoxinogenic mutant strains of Vibrio cholerae using a sensitive and specific reverse passive hemagglutination assay for cholera enterotoxin. Infect. Immun., 19:101, 1978.
Baines, W.B., Vasil, M.L. and Holmes, R.K. Genetic mapping of mutations in independently isolated nontoxinogenic mutants of Vibrio cholerae. Infect. Immun., 19:101, 1978.
Meyers, S.M. and Vasil, M.L. Septic choroditis with serous retinal detachment in dogs from Streptococcus mutans. Infect. Immun., 29:714, 1980.
Hartman, D., Entringer, M.A., Vasil, M.L. and Robinson, W.A. The Effect of Bacterial Infection on Granulopoiesis. Proc. Soc. Exp. Bio. and Med. 167:6, 1981.
Hartman, D., Entringer, M.A., Vasil, M.L. and Robinson, W.A. Reaction of colony stimulating factor and colony forming units in culture in C57/BL mice to infection with three different concentrations of Escherichia coli. J. Cell. Phys. 109:17-24, 1981.
Hartman, D., Entringer, M.A., Vasil, M.L. and Robinson, W.A. Relationship between colony stimulating factor and colony forming unit in culture in non-immunized and immunized C57-BL mice infected with Escherichia coli . Exp. Hematol. 8:1222, 1980.
Gray, G.L. and Vasil, M.L. Isolation, characterization and mapping of mutants deficient in the production of Exotoxin A from Pseudomonas aeruginosa. J. Bacteriol. 147:275, 1981.
Gray, G.L. and Vasil, M.L. Mapping of phospholipase C and alkaline phosphatase deficient mutants in Pseudomonas aeruginosa. Mol & Gen Genet. 183:403, 1981.
Gray, G.L. Berka, R.M. and Vasil, M.L. A mutant of P. aeruginosa non-depressible for orthophosphate-regulated proteins. J. Bacteriol. 147:675, 1981.
Meyers, S.M., Vasil, M.L. and Yamamoto, L. Pathophysiology of multifocal choroiditis with retinal detachment after carotid injection of detachment of Streptococcus mutans and other bacteria in dogs. Invest. Ophthalmol. 22:165, 1982.
Meyers, S.M and Vasil, M.L. Fundus lesions after carotid infection of Streptococcus mutans in monkeys. Infect. Immun. 35:1079, 1982.
Berka, R.M., Gray, G.L. and Vasil, M.L. A Phospholipase C (heat labile hemolysin) from Pseudomonas aeruginosa. Infect. Immun. 34:1071,1981.
Gray, G.L., Berka, R.M. and Vasil, M.L. A phospholipase C regulatory mutation of Pseudomonas aeruginosa which results in the constitutive synthesis of several phosphate repressible proteins. J. Bacteriol. 150:1221, 1982
Vasil, M.L., Berka, R.M., Gray, G.L. and Nakai, H. Cloning of a phosphate-regulated hemolysin gene (Phospholipase C) from Pseudomonas aeruginosa. J. Bacteriol. 152:431, 1982.
Berka, R.M. and Vasil, M.L. Phospholipase C (heat-labile hemolysin) of Pseudomonas aeruginosa: purification and preliminary characterization. J. Bacteriol. 152:239, 1982.
Blaser, M.J., Hopkins, J.A. and Vasil, M.L. Campylobacter jejuni. Outer membrane proteins are antigenic for humans. Infect. Immun. 43:986, 1984.
Blaser, M.J. , Hopkins, J.A., Berka, R.M. and Vasil, M.L. Identification and Characterization of Campylobacter jejuni Outer Membrane Proteins. Infect. Immun. 42: 276-284. 1983.
Gray G.L., Smith, J.S., Vasil, M.L., and Heyneker, H.L. Cloning nucleotide sequence and expression in E. coli of the Exotoxin A structural gene of Pseudomonas aeruginosa . PNAS USA , 81:2645. 1984.
Todd, J.K., Franco-Buff, A., Lawellin, D.W. and Vasil, M.L. Phenotypic distinctiveness of Staphylococcus aureus strains associated with toxic shock syndrome. Infect. Immun. 45:339-344.
Todd, J.K., Lawellin, D.W. and Vasil, M.L. Distinctive protease activity of toxic shock syndrome associated S. aureus, International Congress on Staphylococci, 1984, Warsaw, Poland.
Granstrom, M., Ericsson, A., Standvik, Wretlind, B., Pavlovskis, O.R. and Vasil, M.L. relation between antibody response to Pseudomonas aeruginosa exoproteins and colonization/infection in patients with cystic fibrosis. Acta Ped. Scand. 73:772-777, 1985.
Wretlind, B., Pavlovskis, O.R. and Vasil, M.L. Enzyme-linked Immunosorbent Agent (ELISA) for antibodies in healthy subjects and patients with Pseudomonas Infections, Eur. J. Clin. Microbiol. 4:197-200.
Vasil, M.L., Chamberlin, C. and Grant, C.C.R. Molecular studies of Pseudomonas exotoxin A gene . Infect. Immun. 52:538-548, 1986.
Pritchard, A.E. and Vasil, M.L. Nucleotide sequence and expression of a phosphate-regulated gene encoding a secreted hemolysin of Pseudomonas aeruginosa. J. Bacteriol. 167:291-298, 1986.
Grant, C.C.R. and Vasil, M.L. Analysis of transcription of the Exotoxin A gene of Pseudomonas aeruginosa . J. Bacteriol 168:1112-1119, 1986.
Ogle, J.W., Janda, J.M., Woods, D.E., and Vasil, M.L. Characterization and use of a DNA probe as an epidemiological marker for Pseudomonas aeruginosa. J. Infect . Dis., 1987.
Ostroff, R.M. and Vasil, M.L. Identification of a new Phospholipase C activity by analysis of an insertional mutation in the hemolytic Phospholipase C structural gene of Pseudomonas aeruginosa J. Bacteriol. 169:4597-4601, 1987.
Shen, G.F., Tai, P.C., Pritchard, A.E. and Vasil, M.L. Nucleotide sequences and expression in Escherichia coli of the in-phase overlapping Pseudomonas aeruginosa plc R Genes. J. Bacteriol. 169:4602-4607, 1987.
Ogle, J.W., Reller, L.B. and Vasil, M.L. Development of resistance in Pseudomonas aeruginosa to Imipenem, Norfloxacin, and Ciprofloxacin during therapy proved by typing with a DNA probe. J. Infect. Dis. 157: 743-748 1988.
Hollsing, A.E., Granstrom, M., Vasil, M.L., Wretlind, B. and Strandvik, B. Prospective study of serum antibodies to Pseudomonas aeruginosa exoproteins in cystic fibrosis. J. Clin. Microbiol. 25:1868-1874.1988
Vasil, M.L. Grant ,C.C.R. and Prince, R.W. Regulation of Exotoxin A Synthesis in Pseudomonas aeruginosa : Characterization of toxA-lacZ fusions in wild type and mutant strains. Molecular Microbiology 3:371-381. 1989
Ostroff, R.M. Wretlind, B. and Vasil, M.L. Mutations in the hemolytic phospholipase C operon result in decreased virulence of Pseudomonas aeruginosa grown under phosphate limiting conditions. Infection and Immunity 57:1369-1373, 1989.
Vasil, M.L. Krieg, D. Kuhns, J.S., Shortridge, V. Ogle, J.W. Ostroff, R.M. and Vasil, A.I.. Molecular analysis of hemolytic and phospholipase C activities produced by Pseudomonas cepacia. Infection and Immunity 58:4024-4029. 1990
Pritchard, A.E. and Vasil, M.L. A mosaic genome structure upstream of the exotoxin A gene in Pseudomonas aeruginosa : Possible insertion elements. J. Bacteriol. 172:2020-2028, 1990
Ostroff, R.M., Vasil, A.I., and Vasil, M.L. Molecular comparison of a nonhemolytic and a hemolytic phospholipase C from Pseudomonas aeruginosa J. Bacteriol 172: 5915-5923.1990
Graham, L.M. Vasil, A.I. Vasil, M.L. Voekel, N.F. and Stenmark, K.R. Decreased pulmonary vasoreactivitry in an animal model of chronic Pseudomonas pneumonia Am. Rev. Resp. Dis. 142:221-229. 1990
Anba, J. Bidauf, M. Vasil, M.L. and Lazdunski, A Nucleotide sequence of the Pseudomonas aeruginosa phoB gene, the regulatory gene for the pho regulon. J. Bacteriol. 172:4685-4689. 1990.
Lindgren, V. Ostroff, R.M., Vasil, M.L. and Wretlind, B. Genetic mapping of the structural gene for phospholipase C of Pseudomonas aeruginosa PAO. J. Bacteriol. 172: 1155-1156.1990.
Anderson, D.J , Kuhns, J.S.Vasil, M.L., Gerding, D.N., and Janoff, E.N. Use of DNA fingerprinting and Ribotyping to distinguish Pseudomonas cepacia isolates from a nosocomial outbreak. J. Clin Microbiol. 29:648-649 1991.
Prince, R.W., Storey, D.G. Vasil, A.I. and Vasil, M.L. Regulation of toxA and regA by the Escherichia coli fur gene and identification of a Fur homologue in Pseudomonas aeruginosa PA103 and PA01. Molec. Microbiol.5:2823-2831 1991.
Shortridge, V.D. Pato, M.L. Vasil, A.I. and Vasil, M.L. Physical mapping of virulence associated genes in Pseudomonas aeruginosa by transverse alternating field electrophoresis. Infect and Immun. 59:5915-5924 1991
Wolz, C. Hellstern, E. Haug, M. Galloway, D.R. Vasil, M.L. and Doring, G. Pseudomonas aeruginosa lasB mutant constructed by insertional mutagenesis reveals elastolytic activity due to alkaline proteinase and LasA fragment Molec. Microbiol.5:2125-2131 1991.
Shortridge, V.D. Lazdunski, A. and Vasil, M.L. Osmoprotectants and phosphate regulate expression of phospholipase C in Pseudomonas aeruginosa. Molec. Microbiol 6:863-871 1992
Prince, R.W. Cox, C.D. and Vasil, M.L. Coordinate regulation of siderophore and Exotoxin A production: Molecular Cloning and sequencing of the Pseudomonas aeruginosa fur gene: J. Bacteriol. 175:2589, 1994.
Wiener-Kronish, J.P. Sakuma, T. Kudoh, I. J. Pittet, J. Frank, D. Dobbs, L. Vasil,M.L. and Matthay, M. Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. J. Appl. Physiol.75:1661-1669, 1993.
Hassett, D.J., Woodruff, W.A.,Wozniak, D.J. Vasil, M.L., Cohen, M.S. and Ohman, D.E.Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding iron and manganese-cofactored superoxide dismutase: Demonstration of increased manganese superoxoide dismutase activity in alginate-producing bacteria. J. Bacteriol. 175:7658-7665,1994.
Wolz, C Lehman, R. Vasil, M.L. Bischoff, R. and Doring, G. A new extracellular protein of Pseudomonas aeruginosa PA103 regulated by regA. Microbiology 140: 1755-1761, 1994.
Preston, M.J., Fleiszig, S.M., Zaidi, T.S., goldberg, J.B., Shortridge, V.D., Vasil, M.L., and Pier, G.B. (1995) Rapid and sensitive method for evaluating Pseudomonas aeruginosa virulence factors during corneal infections in mice. Infect. Immun. 63, 3498-3501.
Ochsner, U.A., Vasil, A.I., and Vasil, M.L. (1995) Role of the Ferric Uptake Regulator (FUR) of Pseudomonas aeruginosa in the Regulation of siderophores and Exotoxin A Expression: Purification and Activity on Iron-Regulared Promoters. J. Bacteriol. 177, 7194-7202.
Ochsner UA, and Vasil ML (1996) Gene repression by the "ferric uptake regulator" (FUR) in Pseudomonas aeruginosa Cycle selection of iron-regulated genes. Proc. Natl. Acad. Sci. USA 93, 4409-4414
Hassett, D. J., Sokol, P.A., Howell, M.L., Ma, J.-F., Ochsner, U.A. and Vasil, M.L. (1996) Ferric Uptake Regulator (FUR) Mutants of Pseudomonas aeruginosa Demonstrate Defective Siderophore-Mediated Iron Uptake and altered Aerobid Metabolism. J. Bacteriol. 178, 3996-4003.
Hamood, A.N., Colmer, J.a., Ochsner, U.A., and Vasil, M.L. (1996) Isolation and characterization of a Pseudomonas aeruginosa gene ptxR, which regulates exotoxin A production. Molec. Microbiol. 21, 97-110.
Barton HA, Johnson Z, Vasil AI, and Vasil ML (1996) Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments. Molec. Microbiol. 21, 1001-1017 .
Ochsner UA, Johnson Z, Lamont IL, Cunliffe HE, and Vasil ML (1996) Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated alternative sigma factor PvdS. Molec Microbiol.21, 1019-1028
Johansen KA, Gill RE, and Vasil ML (1996) Biochemical and Molecular Analysis of Phospholipase C and Phospholipase D activity in Mycobacteria. Infection and Immunity 64,3259-3266 .
Hassett, D.J., HJowell, M.L., Sokol, P.A., Vasil, M.L., and Dean, G.E. (1997) Fumerase C activity is elevated in response to iron deprivation and in mucoid, alginate-producing Pseudomonas aeruginosa: Cloning and characterization of fumC and purification of native FumC. J. Bacteriol. 179, 1422-1451.
Hassett, D. J., Howell, M.L., Ochsner, U.A., Vasil, M.L., Johnson, Z., and Dean, G.E. (1997) An operon containing fumC and sodA encoding fumerase C and manganese superoxide dismutase is controlled by the ferric uptake regulator (Fur) in Pseudomonas aeruginosa: fur mutants produce elevatee alginate levels. J. Bacteriol. 179, 14521-459.
Sage, A.E., Vasil, A.I., and Vasil, M.L. (1997) Molecular characterization of mutants in osmoprotectant-dependent induction of phospholipase C in Pseudomonas aeruginosa PAO1. Molec. Microbiol. 23, 43-56.
Sage, A.E., and Vasil, M.L. (1997) Osmoprotectant-dependent expression of plcH, encoding the hemolytic phospholipase C, is subject to novel catabolite repression control in Pseudomonas aeruginosa PAO1. J. Bacteriol. 179, 4874-4881.
Cota-Gomez A, Vasil AI, Kadurugamuwa J, Beveridge TJ, Schweitzer HP, and Vasil ML (1997) PlcR1 and PlcR2 are putative calcium binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa. Infect. and Immun. 65, 2904-2913. .
Konig B, Konig W, and Vasil ML (1997) Role of hemolytic and non-hemolytic phospholipase C from Pseudomonas aeruginosa in interleukin-8 release from human monocytes. J. Med. Microbiol. 46, 471-478 .
Review Articles or Book Chapters
Vasil, M.L., Berka, R.M., Gray, G.L. and Pavlovskis, O.R. Biochemical and genetic studies of iron-regulated (Exotoxin A) and phosphate-regulated (Hemolysin Phospholipase C) virulence factors of Pseudomonas aeruginosa. Antibiot. and Chemother. 36:23-39, 1985.
Vasil, M.L. Pseudomonas aeruginosa --Biology and mechanisms of virulence, epidemiology. J. Pediatr. 108:800-805, 1986.
Vasil, M.L., Ogle, J.W., Grant, C.C.R. and Vasil, M.L. Recombinant DNA approaches to the study of the epidemiology and regulation of Pseudomonas virulence factors. Antibiot. and Chemother. 39:264-278, 1987.
Vasil, M.L. Molecular Biology of Exotoxin A and Phospholipases of Pseudomonas In: A.M. Chakrabarty and S. Silver eds.pp 3-14 Pseudomonas: Biotransformations, Pathogenesis and Evolving Technology American Society for Microbiology. Washington D.C.
Vasil, M.L.,Prince, R.W. and Shortridge, V.D. Exoproducts: Exotoxin A and Phospholipase C in: Pseudomonas aeruginosa the opportunist: Pathogenesis and Disease, Fick, R.B. ed. CRC press Boca Raton, Fla 1992 pp 59-77.
Vasil, M.L., Ostroff, R.M., Shortridge, V.D., Graham, L.M. and Vasil, A.I. Molecular Pathogenesis of hemolysin and phospholipase C of Pseudomonas aeruginosa. Antibiot. and Chemother. 44:34-47
Ogle, J.O. and Vasil, M.L. Molecular Approaches to the epidemiologic typing of Pseudomonas aeruginosa in: Pseudomonas aeruginosa the opportunist: Pathogenesis and Disease, Fick, R.B ed. CRC Boca Raton, Fla, 1992 pp 141-158
Woods, D.E. and Vasil, M.L. Pathogenesis of Pseudomonas aeruginosa infections. in Pseudomonas aeruginosa Infections and Treatment. Baltch, A.L. and Smith, R.P. eds. pp. 21-50
Vasil, M.L., A.I. Vasil, and Shortridge, V.D. Phosphate and osmoprotectants in the pathogenesis of Pseudomonas aeruginosa. in Cellular and molecular biology of phosphate and phosphorylated compounds in microorganisms. Silver, S. and Torriani-gorini, A. eds. ASM press 1994 pp.126-13
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