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Katherine Rennie, Ph.D.

Assistant Professor
Department of Otolaryngology
University of Colorado Health Science Center

Academic phone: 303-315-2923
Email: Katie.Rennie@uchsc.edu


Research Interests:
Ion channels in type I and type II vestibular hair cells.
Synaptic transmission in the vestibular periphery.

Education:
1987 B.Sc. Hons., Physiology, University of Leeds, U.K.
1991 Ph.D., Physiology, University of Bristol, U.K.
1991-1997 Post-doctoral Fellowship, Otolaryngology, University of Texas Medical Branch, Galveston, Texas.

Honors and Awards:
1988 Dale and Rushton Fund (Physiological Society) travel award.
1988 NATO travel award
1994-1997 NRSA Post-doctoral Fellowship (NIDCD).
1997 R03 Small Grant Award (NIDCD).
1998 FIRST Award (NIDCD).
2000-2001 Deafness Research Foundation Award.

Ad Hoc reviewer for the Journal of Physiology and the Journal of Vestibular Research.

Grant reviewer for the National Science Foundation and the Wellcome Trust.

Professional Experience:
1991-1997 Post-doctoral Fellow,
Department of Otolaryngology,
UTMB, Galveston, TX.

1995-1996 Research Associate,
Department of Physiology
University of Bristol, U.K.

1997-2002 Research Assistant Professor,
Department of Otolaryngology,
UTMB, Galveston, TX.

2002 Assistant Professor,
Department of Otolaryngology,
UCD, Denver, CO.

Membership in Scientific Societies:
1993-present Sigma Xi Scientific Research Honors Society.
1995-present Association for Research in Otolaryngology.
2000-present American Physiological Society.
2001-present Society for Neuroscience.

Selected Publications:
Rennie, K. J. and Ashmore, J. F. Ionic currents in isolated vestibular hair cells from the guinea-pig crista ampullaris. Hear. Res. 51:279-292, 1991.

Rennie, K. J. and Ashmore, J. F. Effects of extracellular ATP on hair cells isolated from the guinea-pig semicircular canals. Neuroscience Letts. 160:185-189, 1993.

Rennie, K. J. and Correia, M. J. Potassium currents in mammalian and avian isolated type I semicircular canal hair cells. J. Neurophysiol. 71: 317-329, 1994.

Ricci, A. J., Rennie, K. J. and Correia, M. J. A delayed rectifier conductance shapes the voltage response of type I hair cells. In: New Frontiers of Vestibular Research. B. Cohen and S. Highstein (Eds.) Ann. N. Y. Acad. Sci. 781:690-692, 1996.

Correia, M. J., Ricci, A. J. and Rennie, K. J. Filtering properties of vestibular hair cells: an update. In: New Frontiers of Vestibular Research. B. Cohen and S. Highstein (Eds.) Ann. N. Y. Acad. Sci. 781:138-149, 1996.

Rennie, K. J., Ricci, A. J. and Correia, M. J. Electrical filtering in gerbil isolated type I semicircular canal hair cells. J. Neurophysiol. 75: 2117-2123, 1996.

Ricci, A. J., Rennie, K. J. and Correia, M. J. The delayed rectifier, IKI, is the major conductance in type I vestibular hair cells across vestibular end organs. Pflügers Arch. 432:34-42, 1996.

Ricci, A. J., Rennie, K. J., Cochran, S. L., Kevetter, G. A. and Correia, M. J. Vestibular type I and type II hair cells. 1: Morphological identification in the pigeon and gerbil. J. Vestib. Res. 7:393-406, 1997.

Ricci, A. J., Cochran, S. L., Rennie, K. J. and Correia, M. J. Vestibular type I and type II hair cells. 2: Morphometric comparisons of dissociated pigeon hair cells. J. Vestib. Res. 7:407-420, 1997.

Rennie, K. J., Ashmore, J. F. and Correia, M. J. Evidence for a Na+-K+-Cl- cotransporter in
mammalian type I vestibular hair cells. Am. J. Physiol. Cell Physiol. 273:C1972-C1980, 1997.

Rennie, K. J. and Correia, M. J. Effects of cationic substitutions on delayed rectifier current in type I vestibular hair cells. J. Membr. Biol. 173:139-148, 2000.

Rennie, K. J., Weng, T. X., and Correia, M. J. Effects of KCNQ channel blockers on K+ currents in vestibular hair cells. Am. J. Physiol. Cell Physiol. 280:C473-C480, 2001.

Correia, M. J, Rennie, K. J. and Koo, P. Return of potassium ion channels in regenerated hair cells: Possible pathways and the role of intracellular calcium signaling. In: Vestibular labyrinth in health and disease. J. A. Goebel and S. M. Highstein (Eds.) Ann. N. Y. Acad. Sci. Vol. 942:228-240, 2001.

Rennie, K. J. Modulation of the resting potassium current in type I vestibular hair cells by cGMP. In: Hair cell micromechanics and otoacoustic emissions. C. I. Berlin, L. J. Hood and A. Ricci (Eds.) Singular Press 79-89, 2002.


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