Xin-sheng Deng, MD

Instructor

Education:

  • MD. Xi'an Medical University (1985)

  • MSc. Xi'an Medical University (1988)

  • Subspecialty: Cancer Biology

Postdoctoral Education:

  • Department of Pharmacology, Panum Institute, University of Copenhagen, Denmark (1996-1997)

  • Department of Forensic Medicine, University of Dundee, UK(1997-1998)

  • Department of Clinical Pharmacology, Danish National Hospital. Denmark (1998-1999)

  • Department of Anesthesiology, School of Medicine, University of Colorado Health Sciences Center(1999-2001).

 

 

 

 

 

 

 

       Xin-sheng Deng, MD

Sub Specialty:

Cancer Biology

Research Activities:

  • Breast cancer prevention and treatment, and association with obesity and diabetes.

PUBLICATIONS:

 

1 Deng XS, Hu BW. Degradation kinetics of aconitine in the specimens of rabbits poisoned by aconite. Journal of Xi’an Medical University. 1989;71(2):132-136.

2. Zhang HY, Deng XS, Xiong X. Application of pharmacokinetics to the field of forensic toxicology. Journal of Xi’an Medical University. 1995;16(Suppl.);275-276.

3. Deng XS, Wang Y. High-performance liquid chromatographic analysis of morphine in hair. Journal of Xi’an Medical University. 1995;16(Suppl.) 258-261.

4. Huang J, Deng XS. Methodology improvement: determination of arsenic with hydrogen arsenic-mercury bromine method. Journal of Xi’an Medical University. 1995; 16(Suppl.); 265-266.

5. Zheng HB, Yang YX, Deng XS. Determination of organophosphate pesticides in formalin-fixed post-mortem tissues. Journal of Xi’an Medical University. 1995; 16(Suppl.); 262-263.

6. Deng XS, Hu BW, Zheng HB. A few words about integrating toxicological analysis with forensic toxicology and teaching experience. Journal of North West Medical Education. 1996;14(1):60-61.

7. Deng XS, Hu BW. The role of formalin in the preservation of post-mortem specimens related to poisoning. Journal of Chinese Forensic Medicine. 1996;16(1):26-28

8. Deng XS, Tuo J, Poulsen HE, Loft S. 2-Nitropropane-induced DNA damage in rat bone marrow. Mutat Res. 1997.14;391(3):165-9.

9. Deng XS, Tuo J, Poulsen HE, Loft S. Prevention of oxidative DNA damage in rats by Brussels sprouts. Free Radic Res. 1998; 28(3):323-33.

10. Loft S, Deng XS, Tuo J, Wellejus A, Sorensen M, Poulsen HE. Experimental study of oxidative DNA damage. Free Radic Res. 1998;29(6):525-39.

11. Tuo J, Deng X, Loft S, Poulsen HE. Dexamethasone ameliorates oxidative DNA damage induced by benzene and LPS in mouse bone marrow. Free Radic Res. 1999;30(1):29-36.

12. Deng XS, Kurosu A, Pounder DJ. Detection of anabolic steroids in head hair.

J Forensic Sci. 1999;44(2):343-6.

13. Deng XS, Pounder DJ. Detection of endogenous sex hormones in human hair by GC-MS. Problems of Forensic Sciences (Poland) 1998. 37; 111-121.

14. Deng XS, Simpson VJ. Gas chromatographic-mass spectrometric determination of mice brain etomidate. Journal of Pharmacological and Toxicological methods. 2000 ;43:73-77.

15. Sorensen M, Jensen BR, Poulsen HE, Deng X, Tygstrup N, Dalhoff K and Loft S.

Increase in oxidative DNA damage after administration of a Brussels sprouts extract. Food Chem Toxicol 2001; 39(6):533-40.

16. Deng XS, Simpson VJ. Determination of the volatile anesthetics enflurane and isoflurane in mouse brain by head-space GC-MS. Journal of Pharmacological and Toxicological methods. 2004;49(2):131-6.

17. DENG XS, BLUDEAU P and DEITRICH RA. Formation of ethyl nitrite in mice and humans following ethanol administration. Alcoholism: clinical and experimental research.2003; 27(5)supplement:158A(Abstract).

18. Radcliffe RA, Hoffmann SE, Deng XS, Asperi W, Fay T, Bludeau P, Erwin VG, Deitrich RA. Behavioral characterization of alcohol-tolerant and alcohol-nontolerant rat lines and an f (2) generation. Behav Genet. 2004;34(4):453-63.

19. Radcliffe RA, Erwin VG, Draski L, Hoffmann SE, Edwards J, Deng XS, Bludeau P, Fay T, Lundquist K, Asperi W, and Deitrich RA. QTL mapping for ethanol sensitivity and neurotensin receptor density in and F2 intercross derived from inbred high and low alcohol sensitivity selectively bred rat lines. Alcohol Clin Exp Res. 2004;28(12): 1796-804.

20. Deng XS, Bludeau P and Deitrich RA. Formation of ethyl nitrite in mice and humans following ethanol administration. Alcohol. 2004; 34(2-3):217-223.

21. Radcliffe RA, Bludeau P, Asperi W, Fay T, Deng XS, Erwin VG, Deitrich RA. Confirmation of quantitative trait loci for ethanol sensitivity and neurotensin receptor density in crosses derived from the inbred High and Low Alcohol Sensitive selectively bred rat lines. Psychopharmacology (Berl). 2006;

188(3):343-54.

22. Radcliffe RA, Bludeau P, Deng XS, Erwin VG, Deitrich RA. Short-term selection for acute ethanol tolerance and sensitization from an F2 polulation derived from the high and low alcohol sensitive selectively bred rat lines. Alcohol; 2007 41(8):557-66.

23. Deng XS, Deitrich RA. Ethanol Metabolism and effects: Nitric oxide and its reaction. Current Clinical Pharmacology. 2007.2(2):145-53. Review.

24. Deng XS, Deitrich RA. Putative role of brain acetaldehyde in ethanol addiction. Current Drug Abuse Reviews. 2008.1(1).3-8.Review

25. Radcliffe RA, Bludeau P, Deng XS, Erwin VG, Deitrich RA. A Major QTL for Acute Ethanol Sensitivity in the Alcohol Tolerant and Non-Tolerant Selected Rat Lines. Genes, Brain and Behavior. 2009 (in press).

 

Office Location:

RC1 S, Room # L18-5403D

Contact Information:

Phone: (303) 724-3748

Fax:    (303) 724-3712

Email:  xin-sheng.deng@ucdenver.edu

Mailing Address:

University of Colorado Denver

School of Medicine, Anschutz Medical Campus

Department of Pathology, Mail Stop 8104

12801 E. 17th Ave. RC1 S, Room # L18-5403D

P.O. Box 6511 Aurora, CO 80045-6511