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Evgenia V. Gerasimovskaya, PhD
Assistant Professor of Pediatrics
Evgenia V. Gerasimovskaya, PhD, received her doctoral degree in Biochemistry from the Institute of Experimental Cardiology at the Russian Cardiology Research Center in 1994. Dr. Gerasimovskaya was a Research Scholar with the Pulmonary and Critical Care Division of the University of Pennsylvania in 1997. She completed her first postdoctoral fellowship in the Department of Cellular and Molecular Physiology at Yale University School of Medicine in 1998. In 2001, she completed an additional postdoctoral fellowship in the Department of Pediatrics at the University of Colorado School of Medicine and joined the Department of Pediatrics faculty as a Research Associate.
Dr. Gerasimovskaya’s long-standing research interests involve investigation of molecular and cellular pathways through which extracellular adenine nucleotides and injurious stimuli, as hypoxia, regulate gene expression and phenotypic changes in vascular cells. Specifically, by using biochemical, immunological, pharmacological and genetic approaches she is studying (i) intracellular pathways, which mediate ATP release from vascular cells in response to hypoxia; (ii) metabolism of extracellular adenine nucleotides by membrane ecto-NTPDase(s) to adenosine (ATP->ADP->AMP->Adenosine) and alterations of these pathways under conditions of chronic and acute hypoxia; (iii) purinergic receptors and coupled intracellular signaling pathways underlying transcriptional control of gene expression in vascular cells; and (iv) molecular mechanisms of ligand-independent activation of heterotrimeric G proteins and G protein-coupled receptors by hypoxia.
Dr. Gerasimovskaya is widely published and is an invited reviewer for national medical journals. She is a member of the American Thoracic Society, the American Association for the Advancement of Science, the American Society for Biochemistry and Molecular Biology, the American Society for Cell Biology, and the North American Vascular Biology Organization.
For additional information, please see the column above right.
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Further Information
about
Dr. Gerasimovskaya
Departmental Affiliation:
Publications in PubMed - click for a list of publications with links to abstracts, at the National Library of Medicine PubMed website
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