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Pediatric Heart Lung Center
Research Funding
(listed alphabetically by Principal Investigator)

2006-2009

Academic Training in Pediatric Pulmonary Diseases: National Institutional Research Service Award* **
Principal Investigator: Steven H. Abman, MD
Source: NHLBI, NIH - HL07670-19
Amount: $1,878,079
Term: 1999 - 2009

Genetic Basis for Impaired Angiogenic Signaling in BPD*
Principal Investigator: Steven H. Abman, MD
Source: NHLBI, NIH - RO1 HL085703-01A1
Amount: $3,401,283
Term: 2008 - 2013

Novel Strategies for the Prevention and Treatment of Chronic Lung Disease in Premature Newborns*
Principal Investigator: Steven H. Abman, MD
Source: Thrasher Foundation - PN200601-194
Amount: $441,786
Term: 2006 - 2009

Role of VEGF in Perinatal Pulmonary Hypertension*
Principal Investigator: Steven H. Abman, MD
Source: NHLBI, NIH - RO1 HL68702-06
Amount: $1,084,201
Term: 2007 - 2011

Clinical Proteomics Center in Lung Disease*++***
Principal Investigator: Frank J. Accurso, MD
Source: NHLBI, NIH - U01HL081335-01
Amount: $4,216,147
Term: 2005 - 2009

  • Core A: Administrative
    Principal Investigator: Frank J. Accurso, MD
    Amount: $453,886

  • Core B: Clinical
    Principal Investigator: Steven H. Abman, MD
    Co-Investigators: John P. Kinsella, MD, and D. Dunbar Ivy, MD
    Amount: $862,397

  • Core C: Data Management
    Principal Investigator: Gary O. Zerbe, PhD
    Amount: $884,826

  • Core D: Laboratory
    Principal Investigator: Mark W. Duncan, PhD
    Amount: $1,251,968

  • Core E: Educational
    Principal Investigator: Laurie A. Shroyer, PhD
    Co-Investigator: Robin R. Deterding, MD
    Amount: $604,993

Nonresident Lung Angiogenic Precursor Cells in Bronchopulmonary Dysplasia*
Principal Investigator: Vivek Balasubramaniam, MD
Source: NHLBI, NIH - HL089262-01A1
Amount: $1,250,000
Term: 2008 - 2013

Quantification and Analysis of Endothelial Progenitor Cells in Term and Preterm Umbilical Cord Blood*
Principal Investigator: Vivek Balasubramaniam, MD
Source: TCH Research Institute
Amount: $30,000/yr
Term: 2007 - 2008

Role of Endothelial Progenitor Cells in the Development of BPD*
Principal Investigator: Vivek Balasubramaniam, MD
Source: American Thoracic Society - ATS-06-060
Amount: $100,000
Term: 2007 - 2008

Role of Nitric Oxide in Lung Vascular Development*
Principal Investigator: Vivek Balasubramaniam, MD
Source: INO Therapeutics, Inc. - BALAV2
Amount: $225,000
Term: 2006 - 2009

Role of Vascular Endothelial Growth Factor and Nitric Oxide in Lung Vascular Development*
Principal Investigator: Vivek Balasubramaniam, MD
Source: NHLBI, NIH - K08 HL073893-05
Amount: $653,400
Term: 2003 - 2008

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: Pulmonary Hypertension Association - PN 200305-120
Amount: $312,500
Term: 2004 - 2009

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: NIH Mentored Clinical Scientist Development Award - K08 HL072916
Amount: $130,680/yr
Term: 2004 - 2009

Inhaled Nitric Oxide in the Prevention of Chronic Lung Disease***+
Principal Investigator: John P. Kinsella, MD
Co-Investigators: Steven H. Abman, MD, and Adam A. Rosenberg, MD
Source: NHLBI, NIH - R01 HL64857
Amount: $7,080,990
Term: 2000 - 2008

SOD Treatment of PPHN* ***
Principal Investigator: John P. Kinsella, MD
Co-Investigator: Steven H. Abman, MD
Source: NHLBI, NIH - R21 HL085782-01A1
Amount: $250,000/yr
Term: 2006 - 2011

Pathogenetic Mechanisms of Brochopulmonary Dysplasia**
Principal Investigator: Peter M. Mourani, MD
Co-Investigator: Kurt R. Stenmark, MD
Source: NCRR, NIH - K23 RR021921-03
Amount: $688,148
Term: 2005 - 2010

SCCOR Grant: Lung Vascular Disease in Infants and Children: Mechanisms and Treatment+++****
Principal Investigator: Kurt R. Stenmark, MD
Source: NHLBI, NIH - P50 HL084923
Amount: $12,345,967
Term: 2006 - 2011
  • Project 1: Noninvasive Inhaled NO in Premature Newborns
    Principal Investigator: John P. Kinsella, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $2,457,532
  • Project 3: Advanced Imaging and Diagnostics for Pediatric Pulmonary Hypertension
    Principal Investigators: Robin Shandas, PhD, and D. Dunbar Ivy, MD
    Amount: $2,271,467
  • Project 4: Circulating Fibrocytes in Hyperoxic Lung Vascular Remodeling
    Principal Investigator: Kurt R. Stenmark, MD
    Co-Investigators: Maria Frid, PhD, and Eva N. Grayck, MD
    Amount: $2,038,122
  • Project 5: Hypoxia-Inducible Factors in Neonatal Pulmonary Hypertension
    Principal Investigator: Carl W. White, MD
    Co-Investigators: Aftab Ahmad, PhD, Steven H. Abman, MD, and Theresa R. Grover, MD
    Amount: $2,686,424
  • Core A: Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $531,250
  • Core B: Noninvasive Inhaled Nitric Oxide in Premature Newborns
    Principal Investigator: Ling-Yi, Chang, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $795,448
  • Core C: Clinical Research Skills Development Core
    Principal Investigator: Steven H. Abman, MD
    Amount: $531,222
SCOR Grant: The Impact of Injury on the Immature Pulmonary Circulation+++
Principal Investigator: Kurt R. Stenmark, MD
Source: NHLBI, NIH - P50 HL 57144
Amount: $6,415,929
Term: 2001 - 2006
  • Project I: G-Proteins in Hypoxic Pulmonary Vascular Remodeling
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $2,076,662
  • Project II: Inhaled NO and the Prevention of BPD
    Principal Investigator: Steven H. Abman, MD
    Co-Investigator: John P. Kinsella, MD
    Amount: $1,860,606
  • Project III: Prx Homeobox Genes in Pulmonary Vascular Homeostasis
    Principal Investigator: Peter L. Jones, PhD
    Amount: $1,456,087
  • Clinical Core
    Principal Investigator: John P. Kinsella, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $481,196
  • Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $446,045

2005


Academic Training in Pediatric Pulmonary Diseases: National Institutional Research Service Award*
Principal Investigator: Steven H. Abman, MD
Source: National Institutes of Health - HL07670-17
Amount: $1,878,079
Term: 1999-2009

Effects of High Frequency Oscillatory Ventilation and Inhaled Nitric Oxide in Acute Respiratory Failure in Pediatrics**
Principal Investigator: Emily L. Dobyns, MD
Source: National Institutes of Health, National Center for Research Resources - 5 K23RR16178-03
Amount: $640,190
Term: 2000-2005

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: National Institutes of Health Mentored Clinical Scientist Development Award - K08 HL072916
Amount: $130,680/yr
Term: 2004-2009

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: Pulmonary Hypertension Association
Amount: $62,500/yr
Term: 2004-2009

The Effects of Estrogen on Perinatal Pulmonary Blood Flow***+
Principal Investigator: Thomas A. Parker, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - 1 K08 HL04206
Amount: $590,750
Term: 2000-2005

Inhaled NO for the Prevention of BPD***+
Principal Investigator: John P. Kinsella, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - HL081335-01
Amount: $1,770,000
Term: 2000-2006

SCOR Grant: The Impact of Injury on the Immature Pulmonary Circulation+++
Principal Investigator: Kurt R. Stenmark, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - P50 HL 57144
Amount: $6,415,929
Term: 2001-2006
  • Project I: G-Proteins in Hypoxic Pulmonary Vascular Remodeling
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $2,076,662
  • Project II: Inhaled NO and the Prevention of BPD
    Principal Investigator: Steven H. Abman, MD
    Co-Investigator: John P. Kinsella, MD
    Amount: $1,860,606
  • Project III: Prx Homeobox Genes in Pulmonary Vascular Homeostasis
    Principal Investigator: Peter L. Jones, PhD
    Amount: $1,456,087
  • Clinical Core
    Principal Investigator: John P. Kinsella, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $481,196
  • Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $543,369
Clinical Proteomic Program in Lung Disease*++***
Principal Investigator: Frank J. Accurso, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - HL081335-01
Amount: $930,057
Term: 2005-2009


2003-2004

Academic Training in Pediatric Pulmonary Diseases: National Institutional Research Service Award*
Principal Investigator: Steven H. Abman, MD
Source: National Institutes of Health - HL07670-16
Amount: $1,878,079
Term: 2004-2008

Academic Training in Pediatric Pulmonary Diseases: National Institutional Research Service Award*
Principal Investigator: Steven H. Abman, MD
Source: National Institutes of Health - HL07670-12
Amount: $1,605,925
Term: 1999-2004

Role of Nitric Oxide in the Regulation of Fetal Pulmonary Vasoreactivity and Growth*+
Principal Investigator: Steven H. Abman, MD
Source: March of Dimes Birth Defects Foundation - 6-FY00-124
Amount: $289,740
Term: 2000-2003

SCOR Grant: The Impact of Injury on the Immature Pulmonary Circulation+++
Principal Investigator: Kurt R. Stenmark, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - P50 HL 57144
Amount: $6,415,929
Term: 2001-2006
  • Project I: G-Proteins in Hypoxic Pulmonary Vascular Remodeling
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $2,076,662
  • Project II: Inhaled NO and the Prevention of BPD
    Principal Investigator: Steven H. Abman, MD
    Co-Investigator: John P. Kinsella, MD
    Amount: $1,860,606
  • Project III: Prx Homeobox Genes in Pulmonary Vascular Homeostasis
    Principal Investigator: Peter L. Jones, PhD
    Amount: $1,456,087
  • Clinical Core
    Principal Investigator: John P. Kinsella, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $481,196
  • Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $543,369
Effects of High Frequency Oscillatory Ventilation and Inhaled Nitric Oxide in Acute Respiratory Failure in Pediatrics**
Principal Investigator: Emily L. Dobyns, MD
Source: National Institutes of Health, National Center for Research Resources - 5 K23RR16178-03
Amount: $640,190
Term: 2000-2005

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: National Institutes of Health Mentored Clinical Scientist Development Award - K08 HL072916
Amount: $130,680/yr
Term: 2004-2009

Role of Vascular Endothelial Growth Factor in Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: Pulmonary Hypertension Association
Amount: $62,500/yr
Term: 2004-2009

Vascular Endothelial Growth Factor (VEGF) Treatment for the Prevention of Neonatal Pulmonary Hypertension***+
Principal Investigator: Theresa R. Grover, MD
Source: American Heart Association - National Center Research Program
Amount: $260,000 (only utilized for the first quarter of 2004)
Term: 2004-2007

Role of Endothelium in Perinatal Pulmonary Vasoregulation++
Principal Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health - 5K08 HL03823
Amount: $508,432
Term: 1999-2003

Inhaled Nitric Oxide in the Prevention of Chronic Lung Disease* ***
Principal Investigator: John P. Kinsella, MD
Co-Investigators: Steven H. Abman, MD, and Adam A. Rosenberg, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - R01 HL64857-01A1
Amount: $7,080,990
Term: 2000-2004

The Effects of Estrogen on Perinatal Pulmonary Blood Flow+***
Principal Investigator: Thomas Parker, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - 1 K08 HL04206-01
Amount: $590,750
Term: 2000-2005

2001-2002

Academic Training in Pediatric Pulmonary Diseases: National Institutional Research Service Award*
Principal Investigator: Steven H. Abman, MD
Source: National Institutes of Health - HL07670-12
Amount: $1,605,925
Term: 1999-2004

Home Care Program for Chronic NO Therapy*
Principal Investigator: Steven H. Abman, MD
Source: INO Therapeutics
Amount: $260,000
Term: 2000-2002

Role of Abnormal Lung Growth in the Development of Pulmonary Hypertension*
Principal Investigator: Steven H. Abman, MD
Source: American Heart Association National Grant-In-Aid - 9950265-N
Amount: $165,000
Term: 1999-2001

Role of NO in the Regulation of Fetal Pulmonary Vasoreactivity and Growth*+
Principal Investigator: Steven H. Abman, MD
Source: March of Dimes Birth Defects Foundation - 6-FY00-124
Amount: $289,740
Term: 2000-2003

Role of VEGF in Perinatal Pulmonary Hypertension*+
Principal Investigator: Steven H. Abman, MD
Source: National Institutes of Health - HL68702-01
Amount: $377,500
Term: 2001-2002

Effects of HFOV and iNO in Acute Respiratory Failure in Pediatrics**
Principal Investigator: Emily L. Dobyns, MD
Source: National Institutes of Health, National Center for Research Resources - 5 K23RR16178-03
Amount: $640,190
Term: 2000-2005

Role of Endothelium in Perinatal Pulmonary Vasoregulation++
Principal Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health - 5K08 HL03823
Amount: $508,432
Term: 1999-2003

Inhaled Nitric Oxide in the Prevention of Chronic Lung Disease* ***
Principal Investigator: John P. Kinsella, MD
Co-Investigators: Steven H. Abman, MD, and Adam A. Rosenberg, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - R01 HL64857-01A1
Amount: $7,080,990
Term: 2000-2004

The Effects of Estrogen on Perinatal Pulmonary Blood Flow+***
Principal Investigator: Thomas Parker, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - 1 K08 HL04206-01
Amount: $590,750
Term: 2000-2005

SCOR Grant: The Impact of Injury on the Immature Pulmonary Circulation+++
Principal Investigator: Kurt R. Stenmark, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - P50 HL 57144
Amount: $6,415,929
Term: 2001-2006
  • Project I: G-Proteins in Hypoxic Pulmonary Vascular Remodeling
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $2,076,662
  • Project II: Inhaled NO and the Prevention of BPD
    Principal Investigator: Steven H. Abman, MD
    Co-Investigator: John P. Kinsella, MD
    Amount: $1,860,606
  • Project III: Prx Homeobox Genes in Pulmonary Vascular Homeostasis
    Principal Investigator: Peter L. Jones, PhD
    Amount: $1,456,087
  • Clinical Core
    Principal Investigator: John P. Kinsella, MD
    Co-Investigator: Steven H. Abman, MD
    Amount: $481,196
  • Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $543,369
SCOR Grant: The Impact of Injury on the Immature Pulmonary Circulation+++
Principal Investigator: Kurt R. Stenmark, MD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - P50 HL 57144
Amount: $7,145,567
Term: 1996-2001
  • Project I: SMC Heterogeneity in the Pulmonary Vasculature
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $1,324,572
  • Project II: Perlecan Heparan Sulfates: Molecular Mechanisms Underlying the Control of Vascular Smooth Muscle Cell Replication and Gene Expression During Normal Development and in Neonatal Pulmonary Hypertension
    Principal Investigator: Kurt R. Stenmark, MD
    Co-Investigator: Mary C. M. Weiser-Evans, PhD
    Amount: $962,228
  • Project III: NO-cGMP Cascade in Neonatal Pulmonary Hypertension
    Principal Investigator: Steven H. Abman, MD
    Co-Investigator: John P. Kinsella, MD
    Co-Investigators Clinical Core: John P. Kinsella, MD, and Steven H. Abman, MD
    Amount: $1,960,576
  • Project IV: Oxidants, Energy and Pulmonary Vascular Development
    Principal Investigator: Carl W. White, MD
    Amount: $657,184
  • Clinical Core
    Principal Investigator: Adam A. Rosenberg, MD
    Amount: $1,376,432
  • Administrative Core
    Principal Investigator: Kurt R. Stenmark, MD
    Amount: $371,168

* Supporting research funding in Pulmonology
** Supporting research funding in Critical Care Medicine
*** Supporting research funding in Neonatology
**** Supporting research funding in the Center for Bioengineering and Cardiology
+ Supporting research funding in the Perinatal Research Center
++ Supporting research funding in Cardiology
+++ Supporting research funding in Critical Care Medicine, Neonatology, the Perinatal Research Center and Pulmonology



 
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