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Pediatric Research
  Pediatric research in Colorado reflects the combined efforts of the pediatric faculty who are primarily located at the adjacent campuses of The Children's Hospital (TCH) at Fitzsimons and the University of Colorado Denver (UCD) Anschutz Medical Campus.
In 2008, the Department of Pediatrics ranked first in NIH grant funding for Departments of Pediatrics within U.S. Medical Schools, with a total of $42.4M.
At multiple levels, the affiliation between our institutions has translated into more funding and more "muscle" for the research programs underway at UCD, TCH, and the combined Fitzsimons and Anschutz Medical Campus.
The Clinical Translational Research Center of The Children's Hospital (TCH CTRC) is one of the premier Child Health clinical research centers in North America. TCH CTRC is part of the newly funded Colorado Clinical Translational Sciences Institute (CCTSI), supported by the NIH as part of the nationwide Clinical and Translational Science Award (CTSA) program. The goals of this innovative new program are to transform clinical and translational research and training throughout Colorado in order to speed the application of discoveries into clinical practice. At the TCH CTRC, research is focused on improving child health and understanding disease processes and health issues that specifically affect infants, children, and adolescents. The Center has been continuously funded since 1962 by the NIH and is currently in a five-year funding cycle beginning in 2008.
The Children's Hospital Research Institute (TCH RI) was established in 1992 as a means of increasing the role of The Children's Hospital and community philanthropy in research. At present, support is directed toward funding promising pediatric scientists and pioneering new ideas. The intent is to achieve maximum return on what is a small but growing investment in pediatric research. The TCHRI supports new research initiatives in all disciplines found at TCH (for example nursing and pathology). A Clinical Trials Organization was established at The Children's Hospital to provide additional support to physicians on the medical staff who participate in and supervise clinical trials.
One example of the broad impact of research conducted by the Department of Pediatrics at Children's is the pioneering work of pulmonologist Steven Abman, MD, and neonatologist John Kinsella, MD. Their work on the life-saving impact of inhaled nitric oxide for premature babies with pulmonary hypertension has led to a multicenter, $7.0 million study of the clinical effect of nitric oxide. Another example is the increasing number of intellectual property (IP) disclosures that are being processed by the Technology Transfer Office (TTO), including those by Drs. D. Graham, R. Garcea, B. Tseng, M. Duncan and R. Shandas.
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