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The Children's Hospital Research Institute
RESEARCH FUNDING
Internal Grants
RESEARCH SCHOLAR AWARDS
Nutrient Regulation of Skeletal Muscle Signal Transduction in an Ovine Model of Intrauterine Growth Restriction (IUGR)
Principal Investigator: Laura D. Brown, MD
Source: TCH Research Institute
Amount: $12,191
Term: 2008 - 2009
Nutrient Regulation of Skeletal Muscle Signal Transduction in an Ovine Model of IUGR
Principal Investigator: Laura D. Brown, MD
Source: TCH Research Institute
Amount: $70,000/yr
Term: 2007 - 2008
Mechanisms Responsible for Increased Rho-Kinase Activity and Impaired Angiogenesis in PPHN
Principal Investigator: Jason Gien, MD
Source: TCH Research Institute
Amount: $69,290
Term: 2008 - 2009
Cardiac Cell-Specific Determinants of Reovirus Myocarditic Potential
Principal Investigator: Shelley D. Miyamoto, MD
Source: TCH Research Institute
Amount: $70,000
Term: 2006 - 2009
Combined Influence of Puberty and Obesity on Insulin Resistance in Adolescents
Principal Investigator: Megan Moriarty, MD
Source: TCH Research Institute
Amount: $70,000
Term: 2008 - 2009
Construction and Phenotypic Assessment of Mycobacterial Phospholipase A Deletion Mutants
Principal Investigator: Sarah K. Parker, MD
Source: TCH Research Institute
Amount: $70,000
Term: 2007 - 2009
Mechanism of Reduced Pancreatic Beta-Cell Mass and Insulin Secretion in Intrauterine Growth-Restricted Fetuses and Therapeutic Correction by Glucose and Amino Acids
Principal Investigator: Paul J. Rozance, MD
Source: TCH Research Institute
Amount: $70,000
Term: 2007 - 2009
Endothelial Function and Its Relationship to Cardiovascular Disease Risk Factors in Lean and Overweight Pre- and Early-Pubertal Children
Principal Investigator: Teresa A. Sharp, PhD
Source: TCH Research Institute
Amount: $70,000
Term: 2008 - 2009
Shear Stress Effects in Pulmonary Circulation
Principal Investigator: Wei Tan, PhD
Source: TCH Research Institute
Amount: $70,000
Term: 2007 - 2008
PILOT GRANT AWARDS
Quantification and Analysis of Endothelial Progenitor Cells in Term and Preterm Umbilical Cord Blood
Principal Investigator: Vivek Balasubramaniam, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
Pharmacologic Treatment of Congenital Nephrogenic Diabetes Insipidus
Principal Investigator: Melissa A. Cadnapaphornchai, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
Rhythmic Auditory Stimulation as a Gait Intervention for Children with Cerebral Palsy
Principal Investigator: James J. Carollo, PhD, PE
Source: TCH Research Institute
Amount: $29,950
Term: 2007 - 2008
Idiopathic Pulmonary Arterial Hypertension in Children: A Proteomic Approach to Identify Novel Diagnostic and Prognostic Biomarkers
Principal Investigator: Neil John Davie, PhD
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
Effects of Acute Exercise Epidemiology and Pathogenesis of Novel Coronaviruses
Principal Investigator: Samuel R. Dominguez, MD, PhD
Source: TCH Research Institute
Amount: $30,000
Term: 2007 - 2008
Preliminary Investigation of Proteomics of Pediatric Liver Diseases
Principal Investigators: Mark W. Duncan, PhD, and Ronald J. Sokol, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
Target Validation of the Mer Tyrosine Kinase in the Treatment of Pediatric Astrocytomas
Principal Investigator: Douglas K. Graham, MD, PhD
Source: TCH Research Institute
Amount: $30,000
Term: 2007 - 2008
Recipient Age as a Prognostic Factor in Pediatric Renal Transplantation
Principal Investigator: D. Jane Gralla, PhD
Source: TCH Research Institute
Amount: $19,758
Term: 2006 - 2007
Recipient Age as a Prognostic Factor in Pediatric Renal Transplantation
Principal Investigator: D. Jane Gralla, PhD
Source: TCH Research Institute
Amount: $5,416
Term: 2008 - 2009
Mer Receptor Tyrosine Kinase as a Novel Treatment Target for Pediatric Myeloid Leukemia
Principal Investigator: Amy K. Keating, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2008 - 2009
End-Expired Alveolar (N20) in the Posterior Nasophaynx in 4-9-Year-Old-Children Compared to Flow Meter Settings
Principal Investigator: Ulrich Klein, DDS
Source: TCH Research Institute
Amount: $5,900
Term: 2006 - 2007
Impaired Angiogenic Signaling in Bronchopulmonary Dysplasia
Principal Investigator: Peter M. Mourani, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
Novel Approach to the Pediatric Research Assent Process: Improving Comprehension
Principal Investigator: Theresa A. O’Lonergan, MA
Source: TCH Research Institute
Amount: $29,755
Term: 2008 - 2009
Novel Directions in CBS Deficiency
Principal Investigator: Karl H. Pfenninger, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2008 - 2009
Anterior Knee Pain in Adolescents
Principal Investigator: John Polousky, MD
Source: TCH Research Institute
Amount: $29,801
Term: 2008 - 2009
Pilot Study to Define Nutritional Interrelationships of COQ10, Riboflavin, and Magnesium in the Evaluation and Treatment of Childhood Migraine Headaches
Principal Investigator: Tonia M. Sabo-Graham, MD
Source: TCH Research Institute
Amount: $30,000
Term: 2007 - 2008
Postprandial Lipemia in Obese Compared to Lean Children
Principal Investigator: Teresa A. Sharp, PhD
Source: TCH Research Institute
Amount: $30,000
Term: 2007 - 2008
Measuring Functional Motor Development of Infants and Young Children with the Movement Assessment of Children
Principal Investigator: Linda Sholar, BS, PT
Source: TCH Research Institute
Amount: $29,249
Term: 2006 - 2007
Assessing a Violence-Risk Screening Tool Longitudinally for Primary Care
Principal Investigator: Eric J. Sigel, MD
Source: TCH Research Institute
Amount: $27,966
Term: 2007 - 2008
Isoprostanes: A Marker of Oxidative Injury in Non-Alcoholic Fatty Liver Disease
Principal Investigator: Shikka S. Sundaram, MD, MSCI
Source: TCH Research Institute
Amount: $30,000
Term: 2008 - 2009
Measurement of Voluntary Motor Control in the Affected Upper Extremity of the Child with Hemiplegic Cerebral Palsy
Principal Investigator: Joanne Valvano, PhD, PT
Source: TCH Research Institute
Amount: $30,000
Term: 2006 - 2007
BRIDGE FUND AWARDS
Cerebral Impact of Childhood Sleep Apnea
Principal Investigator: Ann C. Halbower, MD
Source: TCH Research Institute
Amount: $58,514
Term: 2008 - 2009
Bridge Funding for the Colorado Intellectual and Developmental Disabilities Research Center
Principal Investigator: Karl H. Pfenninger, MD
Source: TCH Research Institute
Amount: $122,000
Term: 2008 - 2009
Emergency Department Overcrowding and Quality of Acute Asthma Care for Children
Principal Investigator: Marion R. Sills, MD, MPH
Source: TCH Research Institute
Amount: $25,000
Term: 2008 - 2009
Mechanisms of Hepatic Injury in Cholestasis
Principal Investigator: Ronald J. Sokol, MD
Source: TCH Research Institute
Amount: $77,763
Term: 2006 - 2007
Fostering Healthy Futures Program
Principal Investigator: Heather N. Taussig, PhD
Source: TCH Research Institute
Amount: $62,000
Term: 2006 - 2007
Special Research Emphasis
Clinical Trials Organization
Principal Investigator: Mark J. Abzug, MD
Source: TCH Research Institute
Amount: $50,000/yr
Term: 1990 - ongoing
Children's Outcome Research Program
Principal Investigator: Allison Kempe MD, MPH
Source: TCH Research Institute
Amount: $347,124
Term: 2008 - 2009
Children's Outcome Research Program
Principal Investigator: Allison Kempe MD, MPH
Source: TCH Research Institute
Amount: $299,715
Term: 2007 - 2008
Children's Outcome Research Program
Principal Investigator: Allison Kempe MD, MPH
Source: TCH Research Institute
Amount: $236,336
Term: 2006 - 2007
Developmental Biology
Principal Investigator: Lee Niswander, PhD
Source: TCH Research Institute
Amount: $500,000
Term: 2004 - 2008
External Grants
Colorado Clinical and Translational Sciences Institute
Principal Investigator: Ronald J. Sokol, MD
Co-Directors: William W. Hay, Jr., MD, Michael G. Kahn, MD, PhD, Robert H. Eckel, MD, Mark W. Geraci, MD, Marc Moss, MD, and Andrew Kramer, MD
Consultants: Dexiang Gao, PhD, D. Jane Gralla, PhD, Jeri E. Forster Harwood, PhD, and Zhaoxing Pan, MD, PhD
Source: NCRR, NIH - UL1RR025780, KL2RR025779, TL1RR025778
Amount: $76,155,655
Term: 2008 - 2013
Pediatric Clinical Translational Research Center
Principal Investigator: Richard D. Krugman, MD
Program Director: Ronald J. Sokol, MD
Associate Program Directors: William W. Hay, Jr., MD, and Philip S. Zeitler, MD, PhD
Assistant Program Director: Nancy F. Krebs, MD
Consultants: Dexiang Gao, PhD, D. Jane Gralla, PhD, Jeri E. Forster Harwood, PhD, and Zhaoxing Pan, MD, PhD
Source: NCRR, NIH - MO1 RR00069
Amount: $19,434,966
Term: 2006 - 2008
Pediatric General Clinical Research Center
Principal Investigator: Richard D. Krugman, MD
Program Director: Ronald J. Sokol, MD
Associate Program Directors: William W. Hay, Jr., MD, and Philip S. Zeitler, MD, PhD
Assistant Program Director: Nancy F. Krebs, MD
Consultants: Dexiang Gao, PhD, D. Jane Gralla, PhD, Jeri E. Forster Harwood, PhD, and Zhaoxing Pan, MD, PhD
Source: NCRR, NIH - MO1 RR00069
Amount: $16,884,197
Term: 2001 - 2006
Cancer Center Core Grants - Biostatistics and Bioinformatics Core
Principal Investigator: Paul Bunn, Jr., MD
Consultant: Dexiang Gao, PhD
Source: National Cancer Institute - 5 P30 CA046934-22
Amount: $20,650/yr
Term: 2006 - 2011
SPORE in Lung Cancer - Biostatistics and Informatics Core
Principal Investigator: Paul Bunn, Jr., MD
Consultant: Dexiang Gao, PhD
Source: National Cancer Institute - 2 P50 CA58187-14
Amount: $20,453/yr
Term: 2008 - 2013
Maximizing Protein Growth in the Early Neonatal Period
Consultant: D. Jane Gralla, PhD
Source: NICHD, NIH - R01 HD046752-01A1
Amount: $202,264/yr
Term: 2005 - 2010
Recipient Age as Prognostic Factor in Pediatric Renal Transplantation
Principal Investigator: D. Jane Gralla, PhD
Source: TCH Research Institute
Amount: $33,760/yr
Term: 2006 - 2009
Tacrolimus in Combination with Sirolimus vs. Tacrolimus in Combination with Mycophenolate Mofetil as Maintenance Immunosuppression in Adult Renal Transplantation: Time Trend Analysis
Principal Investigator: D. Jane Gralla, PhD
Source: Wyeth Pharmaceuticals, Inc.
Amount: $30,000
Term: 2007 - 2009
Comparing the Effectiveness of an Anesthetic Continuous-Infusion Device to Oral Analgesia in Orthopedic Post-Operative Pain Control of Children with Cerebral Palsy
Principal Investigator: Frank Chang, MD
Consultant: D. Jane Gralla, PhD
Source: TCH Research Institute
Term: 2005 - 2009
A Double-Blind Placebo-Controlled Study of Risperidone for the Treatment of Anorexia Nervosa
Principal Investigator: Jennifer Hagman, MD
Co-Investigators: D. Jane Gralla, PhD, and Eric J. Sigel, MD
Source: NCRR, NIH - M01 RR00069
Amount: $30,000
Term: 2004 - 2009
Critical Aspects of Successful Management of HIV Infection during Pregnancy: Retrospective Analysis of 150 Pregnancies
Consultant: Jeri E. Forster Harwood, PhD
Source: Abbott Laboratories
Amount: $28,550/yr
Term: 2005 - 2008
Fetal Velocimetry and Amino Acid Transport in Pregnancy
Consultant: Jeri E. Forster Harwood, PhD
Source: NICHD, NIH - 5 R01 1H034837-10
Amount: $250,000/yr
Term: 2003 -2008
Mental Illness Research, Education and Clinical Centers (MIRECC): MIRECC of the VA Rocky Mountain Network
Director: Larry Adler, MD
Consultant: Jeri E. Forster Harwood, PhD
Source: Department of Veteran Affairs
Amount: $32,270/yr
Term: 2008 - 2010
Competency Training, Staff Performance, and Family Outcomes
Consultant: Zhoaxing Pan, MB, PhD
Source: Office of the Director, CDC - 1-U49 CE 300 316
Amount: $35,460
Term: 2004 - 2009
Statistical Support to Gait Research
Consultant: Zhoaxing Pan, MB, PhD
Source: Gait Lab, TCH
Amount: $50,488
Term: 2005 - 2009
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