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Cardiology
Research Funding
(listed alphabetically by Principal Investigator or by Section faculty member involved)
Infant Heart Transplantation from Non-Heart Beating Donors: A Strategy to Reduce Waiting Mortality
Principal Investigator: Mark M. Boucek, MD
Co-Investigators: Biagio A. Pietra, MD, David N. Campbell, MD, D. Dunbar Ivy, MD, and Shelley D. Miyamoto, MD
Source: US Department of Health and Human Services, Health Resources and Services Administration - 1R38OT01314-01-00
Amount: $591,009
Term: 2003-2006
Molecular Epidemiology of Dilated Cardiomyopathy
Principal Investigator: Luisa Mestroni, MD
Co-Investigators: Mark M. Boucek, MD, and Jean L. Cavanaugh, MS, PA-C
Source: National Institutes of Health - 1R01 HL96071-01
Amount: $494,290
Term: 2001-2005
Adventitial Vasa Vasorum Neovascularization Contributes to the Pathogenesis of Pulmonary Hypertension
Principal Investigator: Neil Davie, PhD
Source: American Heart Association - 0560061Z
Amount: $132,000
Term: 2005-2006
Antihypertensive Therapy in Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Robert W. Schrier, MD
Co-Investigator: Curt G. DeGroff, MD
Source: National Institutes of Health - 5 RO1 DK058793
Amount: $1,493,027
Term: 2001-2006
Study of Dexamethasone in Neonatal Lupus CHB
Principal Investigator: Jill Buyon, MD
Collaborator: Karrie L. Dyer, MD
Source: National Institutes of Health - 5R01AR046265-05
Amount: $1,978,608
Term: 2000-2006
Development of a Hospital-Based Home Program for the Use of Inhaled Nitric Oxide in the Chronic Management of Severe Cardiopulmonary Diseases
Co-Investigator: D. Dunbar Ivy, MD
Source: I-NO Therapeutics
Term: 2001-present
A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study of Intravenous Sildenafil in the Treatment of Children, Age 0 to 17 Years with Pulmonary Hypertension After Corrective Cardiac Surgery
Co-Investigator: D. Dunbar, Ivy, MD
Source: Pfizer, Inc.
Term: 2003-present
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study of Oral Sildenafil in the Treatment of Children, Age 1-16 Years, with Pulmonary Arterial Hypertension
Co-Investigator: D. Dunbar Ivy, MD
Source: Pfizer, Inc.
Term: 2003-present
A Phase III Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Sitaxsentan Sodium Treatment with an Open-Label Bosentan Arm in Patients with Pulmonary Arterial Hypertension
Co-Investigator: D. Dunbar Ivy, MD
Source: Encysive Pharmaceuticals, Inc.
Term: 2003-present
A Double-Blind Safety and Efficacy Study of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension Who Have Failed Bosentan Therapy
Co-Investigator: D. Dunbar Ivy, MD
Source: Encysive Pharmaceuticals, Inc.
Term: 2003-present
A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension
Co-Investigator: D. Dunbar Ivy, MD
Source: Encysive Pharmaceuticals, Inc.
Term: 2003-present
A Double-Blind Placebo Controlled Study to Evaluate the Efficacy and Safety of Iloprost in Combination with Bosentan in Subjects
Co-Investigator: D. Dunbar Ivy, MD
Source: Exhale Therapeutics, Inc.
Term: 2003-present
Clinical Proteomics Center in Lung Disease (Core B)
Principal Investigator: Frank J. Accurso, MD
Co-Investigators: D. Dunbar Ivy, MD, and John P. Kinsella, MD
Source: National Institutes of Health, National Heart, Blood and Lung Institute - U01-HL081335
Amount: $908,829
Term: 2005-2009
Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)
Principal Investigator: Joseph D. Kay, MD
Co-Investigator: D. Dunbar Ivy, MD
Source: Sanofi-Synthelabo
Term: 2005-2006
Carvedilol Study
Principal Investigator: Biagio A. Pietra, MD
Co-Investigator: Shelley D. Miyamoto, MD
Source: University of Utah - SB105517-321
Amount: $100,000
Term: 2000-2005
The Mechanism of CD4 T-Cell Dependent Acute Cardiac Allograft Rejection
Principal Investigator: Biagio A. Pietra, MD
Source: National Institutes of Health - 5 R01 HL067976-03
Amount: $1,125,000
Term: 2001-2005
Noninvasive Assessment of Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Co-Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health, National Heart, Blood and Lung Institute - 5R01-HL067399-03
Amount: $900,000
Term: 2001-2006
T32 Graduate Training in Cardiovascular Biomechanics and Imaging
Principal Investigator: Robin Shandas, PhD
Faculty Collaborator: Curt DeGroff, MD
Source: National Institutes of Health, National Heart Lung and Blood Institute - T32 HL 72738
Amount: $850,000
Term: 2003-2008
Sodium Restriction and Arterial Compliance in Older Humans
Principal Investigator: Doug Seals, PhD
Co-Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Institute on Aging - RO1
Amount: $300,000
Term: 2000-2005
Real Time Blood Flow Velocimetry Using Ultrasound
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - R21
Amount: $175,000
Term: 2004-2006
Development of an Ultrasound-Based Micro-Flow Imaging System for Biomedical Applications
Principal Investigator: Robin Shandas, PhD
Source: National Science Foundation - EECS-0225405
Amount: $150,000
Term: 2002-2005
Acquisition of a Particle Image Velocimetry System
Principal Investigator: Jean Herztberg, PhD
Co-Investigator: Robin Shandas, PhD
Source: National Science Foundation
Amount: $150,000
Term: 2002-continuing
Development of a Noninvasive Flow Velocimetry System for Opaque Flows
Principal Investigator: Robin Shandas, PhD
Source: National Science Foundation, Major Research Instrumentation (MRI) Development Award
Amount: $138,000
Term: 2004-2007
Advanced Pulse Sequence Development for Cardiovascular Flow Quantitation Using MRI
Principal Investigator: Robin Shandas, PhD
Source: Siemens MRI Imaging Inc.
Amount: $100,000
Term: 2004-continuing
Effect of Flow on TGF Expression from Endothelial Cells
Principal Investigator: Kristina Rinker, PhD
Co-Investigator: Robin Shandas, PhD
Source: The Whitaker Foundation
Amount: $73,000
Term: 2002-2005
Multi-Scale Modeling and Imaging in Pediatric PHT
Principal Investigator: Robin Shandas, PhD
Collaborators: Neil Davie, PhD, Karrie Dyer, MD, Ruchira Garg, MD, D. Dunbar Ivy, MD, and Lilliam M. Valdes-Cruz, MD
Source: National Institutes of Health, National Heart, Lung, and Blood Institute, Bioengineering Research Partnerships
Amount: $2,762,414
Term: 2005-2010
Development of SMPs for Cardiovascular Application
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering - R21
Amount: $150,000
Term: 2005-2007
Nanoparticles and Nanobubbles for Molecular Imaging in Diabetes
Principal Investigator: Conrad Stoldt, PhD
Co-Investigator: Robin Shandas, PhD
Source: The Butcher Foundation
Amount: $76,000
Term: 2005-2006
Shape Memory Polymers for Endovascular Stents
Principal Investigator: Robin Shandas, PhD
Source: University of Colorado Technology Transfer Office
Amount: $10,000
Term: 2006-2006
Cardiac Synagis/Numax Study
Co-Investigator: Henry M. Sondheimer, MD
Study Coordinator: Kristy Rahimi-Alangi, MS
Source: MedImmune, Inc.
Amount: $100,000
Term: 2005-2006
Assessment of the Effect of Sildenafil on Aerobic Capacity and Pulmonary Artery Pressure Estimates in Patients with Cystic Fibrosis and Pulmonary Hypertension
Principal Investigator: Steven H. Abman, MD
Co-Investigator: Angela T. Yetman, MD
Source: Pfizer, Inc.
Amount: $43,496
Term: 2004-2005
Endothelial Function in Patients with Marfan's Syndrome: A Pilot Investigation
Principal Investigator: Angela T. Yetman, MD
Study Coordinator: Amy L. Taylor, MS
Source: The Children's Hospital Research Institute
Amount: $26,300
Term: 2003-2007
2003-2004
Infant Heart Transplantation from Non-Heart-Beating Donors: A Strategy to Reduce Waiting Mortality
Principal Investigator: Mark M. Boucek, MD
Source: US Department of Health and Human Services, Health Resources and Services Administration - 1R38OT01314-01-00
Amount: $590,000
Term: 2003-2006
Molecular Epidemiology of Dilated Cardiomyopathy
Principal Investigator: Luisa Mestroni, MD
Co-Investigators: Mark M. Boucek, MD, and Jean Lascor, MS, PA-C
Source: National Institutes of Health - 1R01 HL96071-01
Amount: $494,290
Term: 2001-2006
Carvedilol Study
Principal Investigator: Mark M. Boucek, MD
Co-Investigator: Jean Lascor, MS, PA-C
Source: University of Utah - SB105517-321
Amount: $100,000
Term: 2000-2005
Prospective Study of Dexamethasone in Neonatal Lupus Congenital Heart Block - Aim 1, Aim 2, Aim 2a
Principal Investigator: Jill Buyon, MD
Co-Investigator: Curt G. DeGroff, MD
Source: Hospital for Joint Diseases - 1R01Ar046265-10A1
Amount: $1,978,608
Term: 2002-2003
Antihypertensive Therapy in Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Robert W. Schrier, MD
Co-Investigator: Curt G. DeGroff, MD
Source: National Institutes of Health - 5 R01 DK058793
Amount: $1,493,027
Term: 2001-2006
Development of a Cardiac Screening Device Using Artificial Neural Networks
Principal Investigator: Curt G. DeGroff, MD
Source: American Heart Association - 0256013Z
Amount: $110,000
Term: 2002-2004
Phase I: Development of a Cardiac Screening Device
Consultant: Curt G. DeGroff, MD
Source: National Institutes of Health, Small Business Innovative Research
Amount: $100,000
Term: 2003-2004
Role of Endothelium in Perinatal Pulmonary Vasoregulation*
Principal Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health - 5K08 HL03823
Amount: $508,432
Term: 1999-2003
Development of a Hospital-Based Home Program for the Use of Inhaled Nitric Oxide in the Chronic Management of Severe Cardiopulmonary Diseases
Co-Investigator: D. Dunbar Ivy, MD
Source: iNO Therapeutics
Term: 2001-present
A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study of Intravenous Sildenafil in the Treatment of Children, Aged 0 to 17 Years with Pulmonary Hypertension After Corrective Cardiac Surgery
Principal Investigator: D. Dunbar, Ivy, MD
Source: Pfizer, Inc.
Term: 2003-present
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Parallel Group Study of Oral Sildenafil in the Treatment of Children, Aged 1-16 Years, with Pulmonary Arterial Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: Pfizer, Inc.
Term: 2003-present
A Phase III Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Sitaxsentan Sodium Treatment with an Open-Label Bosentan Arm in Patients with Pulmonary Arterial Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: Encysive
Term: 2003-present
A Double-Blind Safety and Efficacy Study of Sitaxsentan Sodium Treatment in Patients with Pulmonary Hypertension Who Have Failed Bosentan Therapy
Principal Investigator: D. Dunbar Ivy, MD
Source: Encysive
Term: 2003-present
A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: Encysive
Term: 2003-present
A Double-Blind Placebo Controlled Study to Evaluate the Efficacy and Safety of Iloprost in Combination with Bosentan in Subjects
Principal Investigator: D. Dunbar Ivy, MD
Source: Exhale Therapeutics
Term: 2003-present
The Mechanism of CD4 T Cell Dependent Acute Cardiac Allograft Rejection
Principal Investigator: Biagio A. Pietra, MD
Source: National Institutes of Health - 5 R01 HL067976-03
Amount: $1,125,000
Term: 2001-2005
Prospective Assessment After Pediatric Cardiac Ablation (PAPCA)
Principal Investigator: Michael S. Schaffer, MD
Source: National Heart, Blood and Lung Institute - R01-HL58620-01A1
Amount: $28,500
Term: 1999-2003
Noninvasive Assessment of Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Heart, Blood and Lung Institute - 5R01-HL067399-03
Amount: $900,000
Term: 2001-2005
T32 Graduate Training in Cardiovascular Biomechanics and Imaging
Principal Investigator: Robin Shandas, PhD
Faculty Collaborator: Curt G. DeGroff, MD
Source: National Institutes of Health, National Heart, Blood and Lung Institute
Amount: $850,000
Term: 2003-2008
Sodium Restriction and Arterial Compliance in Older Humans
Principal Investigator: Doug Seals, PhD
Co-Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Institute on Aging - R01
Amount: $250,000
Term: 2000-2004
Development of a Noninvasive Method to Estimate Pulmonary Vascular Resistance in Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association, National Chapter - 0151364Z
Amount: $225,000
Term: 2001-2003
Real-Time Blood Flow Velocimetry Using Ultrasound
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - R21
Amount: $175,000
Term: 2004-2006
Development of an Ultrasound-Based Micro-Flow Imaging System for Biomedical Applications
Principal Investigator: Robin Shandas, PhD
Source: National Science Foundation - EECS-0225405
Amount: $150,000
Term: 2002-2004
Acquisition of a Particle Image Velocimetry System
Principal Investigator: Jean Herztberg, PhD
Co-Investigator: Robin Shandas, PhD
Source: National Science Foundation
Amount: $150,000
Term: 2002-ongoing
Development of a Noninvasive Flow Velocimetry System for Opaque Flows
Principal Investigator: Robin Shandas, PhD
Source: National Science Foundation, Major Research Instrumentation (MRI) Development Award
Amount: $138,000
Term: 2004-2007
Noninvasive Assessment of Prosthetic Heart Valve Function
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association, Desert/Mountain Affiliate
Amount: $110,000
Term: 2001-2003
Advanced Pulse Sequence Development for Cardiovascular Flow Quantitation Using MRI
Principal Investigator: Robin Shandas, PhD
Source: Siemens MRI Imaging Inc.
Amount: $100,000
Term: 2004-ongoing
Effect of Flow on TGF Expression from Endothelial Cells
Principal Investigator: Kristina Rinker, PhD
Co-Investigator: Robin Shandas, PhD
Source: The Whitaker Foundation
Amount: $73,000
Term: 2002-2005
Biomechanics of Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: March of Dimes Birth Defects Foundation
Amount: $70,000
Term: 2001-2004
Development of a Remote Telemetry System for Noninvasive Evaluation of Prosthetic Heart Valve Function In Vivo
Principal Investigator: Robin Shandas, PhD
Source: Colorado Commission on Higher Education/Colorado Alliance for Bioengineering
Amount: $56,000
Term: 2002-2003
Development of Noninvasive Methods to Quantify Prosthetic Valve Function: In Vitro Studies
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association, Desert/Mountain Affiliate
Amount: $50,000
Term: 2001-2003
Pulmonary Reactivity in the Neonatal Hypoxic Calf Model
Principal Investigator: Janice Bright, DVM
Co-Investigator: Robin Shandas, PhD
Source: Colorado State University Research Program
Amount: $34,000
Term: 2002-2003
Filtration Efficiency of a Depth Distal-Protection Filter
Principal Investigator: Robin Shandas, PhD
Source: POSSIS Inc.
Amount: $20,000
Term: 2004
Synagis Prophylaxis Against RSV Infections for Infants with Congenital Heart Disease
Principal Investigator: Henry M. Sondheimer, MD
Source: MedImmune, Inc.
Amount: $120,000
Term: 1998-2003
Assessment of the Effect of Sildenafil on Aerobic Capacity and Pulmonary Artery Pressure Estimates in Patients with Cystic Fibrosis and Pulmonary Hypertension
Principal Investigator: Steven H. Abman, MD
Co-Investigator: Angela T. Yetman, MD
Source: Pfizer, Inc.
Amount: $43,496
Term: 2004-2005
2001-2002
Molecular Epidemiology of Dilated Cardiomyopathy
Principal Investigator: Luisa Mestroni, MD
Co-Investigators: Mark M. Boucek, MD, and Jean Lascor, MS, PA-C
Source: National Institutes of Health - 1RO1 HL96071-01
Amount: $494,290
Term: 2001-2006
Carvedilol Study
Principal Investigator: Mark M. Boucek, MD
Co-Investigator: Jean Lascor, MS, PA-C
Source: University of Utah - SB105517-321
Amount: $55,000
Term: 2000-2003
Development of a Cardiac Screening Device Using Artificial Neural Networks
Principal Investigator: Curt G. DeGroff, MD
Source: American Heart Association - 0256013Z
Amount: $55,000
Term: 2002-2003
Optimization of the Right Heart Bypass Procedure: A Numerical, In Vitro and In Vivo Investigation
Principal Investigator: Curt G. DeGroff, MD
Co-Investigator: Lilliam M. Valdes-Cruz, MD
Source: American Heart Association, Scientist Development Award - 9730235N
Amount: $260,000
Term: 1998-2001
Characterization Role of Fas/Fas L in Transplantation
Principal Investigator: Richard Duke, PhD
Co-Investigator: Biagio Pietra, MD
Source: National Institutes of Health
Amount: $110,000
Term: 1999-2004
Three-Dimensional Ultrasound Methods for Aortic Stenosis: In Vitro and Prospective Clinical Study
Principal Investigator: Shuping Ge, MD
Co-Investigators: Robin Shandas, PhD, and Lilliam M. Valdes-Cruz, MD
Source: American Heart Association, Postdoctoral Fellowship - 00204592
Amount: $95,000
Term: 2000-2002
A Double-Blind, Randomized, Placebo-Controlled Study to Assess the Effects of RO 47-0203 (Bosentan on Exercise Capacity in Patients with Pulmonary Arterial Hypertension Protocol No. AC-052-352)
Principal Investigator: D. Dunbar Ivy, MD
Source: Sanofi-Synthelabo
Term: 2000-2001
A Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Brevibloc (Esmolol Hydrochloride) for the Treatment of Hypertension in Infants and Children after Surgical Repair of Coarctation of the Aorta
Principal Investigator: D. Dunbar Ivy, MD
Source: Baxter Healthcare Corporation
Term: 2001
A Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: ICOS-Texas Biotechnology
Term: 2001
An Extension Study to Evaluate the Long-Term Safety and Pharmacokinetics of Sitaxsentan Sodium Treatment in Patients with Pulmonary Arterial Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: ICOS-Texas Biotechnology
Term: 2001
An International, Multicenter, Uncontrolled, Open Evaluation of Chronic UT-15 plus Conventional Therapy to Conventional Therapy in Patients with Pulmonary Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: United Therapeutics
Term: 1999-2002
Bosentan Protocol 354
Principal Investigator: D. Dunbar Ivy, MD
Source: Actelion Pharmaceuticals Ltd.
Amount: $80,000
Term: 2001
Pharmacokinetics and Tolerability of Tracleer (Bosentan) in Pediatric Patients with Pulmonary Arterial Hypertension: Single and Multiple Oral Doses
Principal Investigator: D. Dunbar Ivy, MD
Source: Actelion Pharmaceuticals Ltd.
Term: 2001
Prophylactic Use of Primacor® in Patients at High Risk of Developing Low Cardiac Output Syndrome Following Cardiac Surgery (Protocol No. E IV 7867)
Principal Investigator: D. Dunbar Ivy, MD
Source: Sanofi-Synthelabo
Term: 2000-2001
Role of Endothelium in Perinatal Pulmonary Vasoregulation*
Principal Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health - 5K08 HL03823
Amount: $508,432
Term: 1999-2003
Role of the Endothelin B Receptor in Pulmonary Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: American Heart Association, Desert/Mountain Affiliate - 9951441Z
Amount: $80,000
Term: 1999-2001
T32
Principal Investigator: Angela Lorts, MD
Source: Public Health Services - HL-07670-13
Amount: $40,772
Term: 2002-2003
Cellular Cardiac Allograft Rejection
Principal Investigator: Biagio Pietra, MD
Source: National Institutes of Health, National Heart, Blood and Lung Institute, Mentored Clinical Scientist Award - KO825-33569
Amount: $280,800
Term: 1997-2001
Role of C4 in Allograft Rejection
Principal Investigator: Biagio Pietra, MD
Source: National Institutes of Health - 1 R01 HL67976-01
Amount: $950,000
Term: 2001-2005
Prospective Assessment after Pediatric Cardiac Ablation (PAPCA)
Principal Investigator: Michael S. Schaffer, MD
Source: National Institutes of Health, National Heart, Blood and Lung Institute - RO1-HL58620-01A1
Amount: $28,500
Term: 1999-2003
Development of Noninvasive Means of Estimating Pulmonary Vascular Resistance in Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Co-Investigator: Lilliam M. Valdes-Cruz, MD
Source: American Heart Association Colorado Chapter - 99513782
Amount: $80,000
Term: 1999-2001
Development of a Noninvasive Method to Estimate Pulmonary Vascular Resistance in Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association, National Chapter - 0151364Z
Amount: $225,000
Term: 2001-2003
Development of a Remote Telemetry System for Noninvasive Evaluation of Prosthetic Heart Valve Function In Vivo
Principal Investigator: Robin Shandas, PhD
Source: Colorado Commission on Higher Education/ Colorado Alliance for Bioengineering
Amount: $56,000
Term: 2002-2003
Development of an Ultrasound-Based Microflow Imaging System for Biomedical Applications
Principal Investigator: Robin Shandas, PhD
Source: National Science Foundation - EECS-0225405
Amount: $150,000
Term: 2002-2004
Fluid Mechanics of Ventricular Filling
Principal Investigator: Robin Shandas, PhD
Co-Investigator: Lilliam M. Valdes-Cruz, MD
Source: The Whitaker Foundation - RG 98-0162
Amount: $205,587
Term: 1998-2001
Noninvasive Assessment of Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Heart, Blood and Lung Institute - 1RO1-HL673993
Amount: $900,000
Term: 2001-2005
Noninvasive Assessment of Prosthetic Heart Valve Function
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association Colorado Chapter
Amount: $110,000
Term: 2001-2003
T32 Graduate Training in Cardiovascular Biomechanics and Imaging
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health, National Heart, Blood and Lung Institute
Amount: $878,000
Term: 2003-2008
Cardiac Synagis Study
Principal Investigator: Henry M. Sondheimer, MD
Source: Medimmune, Inc. - MI-CP048
Amount: $200,000
Term: 2000-2002
1999-2000
Optimization of the Right Heart Bypass Procedure: A Numerical, In Vitro and In Vivo Investigation
Principal Investigator: Curt DeGroff, MD
Source: American Heart Association, Scientist Development Award
Amount: $260,000
Term: January 1998-December 2001
Development of Intelligent Stethescope
Principal Investigator: Curt DeGroff, MD
Source: The Children's Hospital Research Institute Pilot Grant
Amount: $30,000
Term: January 1999-June 2000
Development of a Non-Invasive Method for Quantitative Assessment of Pulmonary Vascular Resistance in Children by Color Doppler M-Mode Measurement of Velocity Propagation in the Pulmonary Artery
Principal Investigator: Shuping Ge, MD
Co-Investigator: Robin Shandas, PhD
Source: Thorkildsen Fellowship
Amount: $25,000
Term: July 1999-June 2000
Three-Dimensional Ultrasound Methods for Aortic Stenosis: In Vitro and Prospective Clinical Study
Principal Investigator: Shuping Ge, MD
Co-Investigator: Robin Shandas, PhD
Source: American Heart Association, Postdoctoral Fellowship
Amount: $95,000
Term: July 2000-June 2002
Basil O'Connor Starter Scholar Award
Principal Investigator: D. Dunbar Ivy, MD
Source: March of Dimes Birth Defects Foundation
Amount: $80,000
Term: January 1997-January 1999
Role of the Endothelium in Perinatal Pulmonary Hypertension
Principal Investigator: D. Dunbar Ivy, MD
Source: American Heart Association, Desert/Mountain Affiliate
Amount: $80,000
Term: July 1999-June 2001
Role of Endothelium in Perinatal Pulmonary Vasoregulation*
Principal Investigator: D. Dunbar Ivy, MD
Source: National Institutes of Health - K08
Amount: $508,432
Term: September 1999-August 2003
Cellular Cardiac Allograft Rejection
Principal Investigator: Biagio Pietra, MD
Source: National Institutes of Health Mentored Clinical Scientist Award, National Heart, Blood and Lung Institute
Amount: $70,200
Term: January 1997-January 2001
Characterization Role of Fas/FasL in Transplantation
Principal Investigator: Richard Duke, PhD
Co-Investigator: Biagio Pietra, MD
Source: National Institutes of Health
Amount: $110,000
Term: July 1999-June 2004
D,L Sotalol Pharmicokinetics/Pharmicodynamics in Pediatric Patients
Principal Investigator: Michael S. Schaffer, MD
Source: Berlex
Amount: $85,000
Term: 1999
Prospective Assessment After Pediatric Cardiac Ablation
Principal Investigator: George VanHare, MD
Co-Investigator: Michael S. Schaffer, MD
Source: National Lung Heart Blood Institute
Amount: $28,500
Term: 1999
Effective Flow Areas of Bileaflet Mechanical Valves
Principal Investigator: Robin Shandas, PhD
Source: National Institutes of Health
Amount: $140,966
Term: August 1996-July 1999
Fluid Mechanics of Ventricular Filling
Principal Investigator: Robin Shandas, PhD
Source: The Whitaker Foundation
Amount: $205,587
Term: September 1998-August 2001
Three-Dimensional Ultrasound Imaging and Finite Element Analysis of a Bioprosthetic Heart Valve: Animal Studies
Principal Investigator: Robin Shandas, PhD
Source: St. Jude Medical Inc.
Amount: $39,000
Term: August 1998-July 1999
Development of Non-Invasive Means of Estimating Pulmonary Vascular Resistance in Pediatric Pulmonary Hypertension
Principal Investigator: Robin Shandas, PhD
Source: American Heart Association Colorado Chapter
Amount: $80,000
Term: September 1999-August 2001
Development of a Remote Telemetry System to Sense Prosthetic Valve Function
Principal Investigator: Robin Shandas, PhD
Source: The Children's Hospital Research Institute Pilot Grant
Amount: $30,000
Term: November 1999-November 2000
Cardiac Synagis Study
Principal Investigator: Henry Sondheimer, MD
Source: MedImmune, Inc.
Amount: $100,000
Term: August 1998-May 1999
Cardiac Synagis Study
Principal Investigator: Henry Sondheimer, MD
Source: Medimmune, Inc.
Amount: $35,000
Term: September 1999-May 2000
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