|
|
Critical Care Medicine
Publications
Banks MF, Gerasimovskaya EV, Tucker DA, Frid MG, Carpenter TC, Stenmark KR. Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts. J Appl Physiol. 2005 Feb;98(2):732-8. [PubMed]
Carpenter TC, Dobyns EL, Mateev SN, Mourani PM, Ferguson MA, Stenmark KR. Critical care. In: Hay WW Jr., Hayward AR, Levin ML, Sondheimer JM, Deterding RR, editors. Current pediatric diagnosis and treatment. 17th ed. New York: McGraw Hill; 2005.
Carpenter TC, Schomberg S, Stenmark KR. Endothelin-mediated increases in lung VEGF content promote vascular leak in young rats exposed to viral infection and hypoxia. Am J Physiol Lung Cell Mol Physiol. 2005 Dec;289(6):L1075-82. [PubMed]
Frid MG, Brunetti JA, Burke DL, Carpenter TC, Davie NJ, Stenmark KR. Circulating mononuclear cells with a dual, macrophage-fibroblast phenotype contribute robustly to hypoxia-induced pulmonary adventitial remodeling. Chest. 2005 Dec;128(6 Suppl):583S-584S. [PubMed]
Gerasimovskaya EV, Davie NJ, Ahmad S, Tucker DA, White CW, Stenmark KR. Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling. Chest. 2005 Dec;128(6 Suppl):608S-610S. [PubMed]
Gerasimovskaya EV, Tucker DA, Stenmark KR. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation. J Appl Physiol. 2005 Feb;98(2):722-31. [PubMed]
Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR. Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways. J Biol Chem. 2005 Jan 21;280(3):1838-48. [PubMed]
Liu E, MacKenzie T, Dobyns EL, Parikh CR, Karrer FM, Narkewicz MR, Sokol RJ. Characterization of acute liver failure and development of a continuous risk of death staging system in children. J Hepatol. 2006 Jan;44(1):134-41. [PubMed]
Narkewicz MR, Kasaragod A, Lucia MS, Pflummer S, Sokol RJ, Stenmark KR. Connective tissue growth factor expression is increased in biliary epithelial cells in biliary atresia. J Pediatr Surg. 2005 Nov;40(11):1721-5. [PubMed]
Reeves JT, Linehan JH, Stenmark KR. Distensibility of the normal human lung circulation during exercise. Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L419-25. [PubMed]
Short M, Fox S, Stenmark KR, Das M. Hypoxia-induced alterations in protein kinase C zeta signaling result in augmented fibroblast proliferation. Chest. 2005 Dec;128(6 Suppl):582S. [PubMed]
Stenmark KR, Abman SH. Lung vascular development: implications for the pathogenesis of bronchopulmonary dysplasia. Annu Rev Physiol. 2005;67:623-61. [PubMed]
Stenmark KR, Balasubramaniam V. Angiogenic therapy for bronchopulmonary dysplasia: rationale and promise. Circulation. 2005 Oct 18;112(16):2383-5. [PubMed]
Stenmark KR, Davie NJ, Reeves JT, Frid MG. Hypoxia, leukocytes, and the pulmonary circulation. J Appl Physiol. 2005 Feb;98(2):715-21. [PubMed]
Stenmark KR, McMurtry IF. Vascular remodeling versus vasoconstriction in chronic hypoxic pulmonary hypertension: a time for reappraisal? Circ Res. 2005 Jul 22;97(2):95-8. [PubMed]
2004
Bailey M, Pillarisetti S, Jones PL, Xiao H, Simionescu D, Vyavahare N. Involvement of matrix metalloproteinases and tenascin-C in elastin calcification. Cardiovasc Pathol. 2004 May-Jun;13(3):146-55. [PubMed]
Bemis L, Chan DA, Finkielstein CV, Qi L, Sutphin PD, Chen X, Stenmark K, Giaccia AJ, Zundel W. Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5. Genes Dev. 2004 Apr 1;18(7):739-44. [PubMed]
Carpenter T. Novel approaches in conventional mechanical ventilation for paediatric acute lung injury. Paediatr Respir Rev. 2004 Sep;5(3):231-7. [PubMed]
Carpenter TC, Stenmark KR. Predisposition of infants with chronic lung disease to respiratory syncytial virus-induced respiratory failure: a vascular hypothesis. Pediatr Infect Dis J. 2004 Jan;23(1 Suppl):S33-40. [PubMed]
Davie NJ, Crossno JT Jr, Frid MG, Hofmeister SE, Reeves JT, Hyde DM, Carpenter TC, Brunetti JA, McNiece IK, Stenmark KR. Hypoxia-induced pulmonary artery adventitial remodeling and neovascularization: contribution of progenitor cells. Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L668-78. [PubMed]
Frid MG, Aldashev AA, Crossno JT, Jorgensen JM, Kale VA, Stenmark KR. Yin and Yang of an endothelial cell: from normal to the extreme in growth, secretion, and transdifferentiation capabilities. Paediatr Respir Rev. 2004;5 Suppl A:S253-7. [PubMed]
Frid MG, Davie NJ, Stenmark KR. Heterogeneity in hypoxia-induced pulmonary artery smooth muscle cell proliferation. In: Yuan JX-J, editor. Hypoxic pulmonary vasoconstriction: cellular and molecular mechanisms. Boston: Kluwer Academic Publishers; 2004.
Garl PJ, Wenzlau JM, Walker HA, Whitelock JM, Costell M, Weiser-Evans MC. Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN. Circ Res. 2004 Feb 6;94(2):175-83. [PubMed]
Gupta VK, Grayck EN, Cheifetz IM. Heliox administration during high-frequency jet ventilation augments carbon dioxide clearance. Respir Care. 2004 Sep;49(9):1038-44. [PubMed]
Hogbom M, Stenmark P, Voevodskaya N, McClarty G, Graslund A, Nordlund P. The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass. Science. 2004 Jul 9;305(5681):245-8. [PubMed]
Holmfeldt P, Stenmark S, Gullberg M. Differential functional interplay of TOGp/XMAP215 and the KinI kinesin MCAK during interphase and mitosis. EMBOJ 2004 Feb 11;23(3):627-37. [PubMed]
Humbert M, Morrell NW, Archer SL, Stenmark KR, MacLean MR, Lang IM, Christman BW, Weir EK, Eickelberg O, Voelkel NF, Rabinovitch M. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol. 2004 Jun 16;43(12 Suppl S):13S-24S. [PubMed]
Ihida-Stansbury K, McKean DM, Gebb SA, Martin JF, Stevens T, Nemenoff R, Akeson A, Vaughn J, Jones PL. Paired-related homeobox gene Prx1 is required for pulmonary vascular development. Circ Res. 2004 Jun 11;94(11):1507-14. [PubMed]
Mamo LB, Suliman HB, Giles BL, Auten RL, Piantadosi CA, Nozik-Grayck E. Discordant extracellular superoxide dismutase expression and activity in neonatal hyperoxic lung. Am J Respir Crit Care Med. 2004 Aug 1;170(3):313-8. [PubMed]
Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation. 2004 Mar 16;109(10):1299-306. [PubMed]
Mourani PM, Ivy DD, Gao D, Abman SH. Pulmonary vascular effects of inhaled nitric oxide and oxygen tension in bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2004 Nov 1;170(9):1006-13. [PubMed]
Short M, Nemenoff RA, Zawada WM, Stenmark KR, Das M. Hypoxia induces differentiation of pulmonary artery adventitial fibroblasts into myofibroblasts. Am J Physiol Cell Physiol. 2004 Feb;286(2):C416-25. [PubMed]
2003
Ahmad S, Ahmad A, Gerasimovskaya E, Stenmark KR, Allen CB, White CW. Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase. Am J Respir Cell Mol Biol. 2003 Feb;28(2):179-87. [PubMed]
Carpenter T, Schomberg S, Steudel W, Ozimek J, Colvin K, Stenmark K, Ivy DD. Endothelin B receptor deficiency predisposes to pulmonary edema formation via increased lung vascular endothelial cell growth factor expression. Circ Res. 2003 Sep 5;93(5):456-63. [PubMed]
Carpenter TC, Dobyns EL, Lane J, Mourani PM, Robinson A, Ferguson MA, Stenmark KR. Critical Care. In: Hay WW Jr., Hayward AR, Levin MJ, Sondheimer JM, editors. Current pediatric diagnosis and treatment. 16th ed. New York: McGraw-Hill; 2003.
Carpenter TC, Schomberg S, Nichols C, Stenmark KR, Weil JV. Hypoxia reversibly inhibits epithelial sodium transport but does not inhibit lung ENaC or Na-K-ATPase expression. Am J Physiol Lung Cell Mol Physiol. 2003 Jan;284(1):L77-83. [PubMed]
Carpenter TC. Corticosteroids in the treatment of severe Mycoplasma encephalitis in children. Infect Dis 2003; 2:8-9.
Cuevas BD, Abell AN, Witowsky JA, Yujiri T, Johnson NL, Kesavan K, Ware M, Jones PL, Weed SA, DeBiasi RL, Oka Y, Tyler KL, Johnson GL. MEKK1 regulates calpain-dependent proteolysis of focal adhesion proteins for rear-end detachment of migrating fibroblasts. EMBO J. 2003 Jul 1; 22(13): 3346-55. [PubMed]
Elliot J, Woodward J, Jones PL, Plant A. Thin films of collagen affect smooth muscle cell morphology. Langmuir. 2003 Mar 4;19(5):1506-14.
Gebb SA, Jones PL. Hypoxia and lung branching morphogenesis. Adv Exp Med Biol. 2003; 543: 117-25. [PubMed]
Jones PL. Homeobox genes in pulmonary vascular development and disease. Trends Cardiovasc Med. 2003 Nov; 13(8): 336-45. [PubMed]
Kaplan-Albuquerque N, Garat C, Desseva C, Jones PL, Nemenoff RA. Platelet-derived growth factor-BB-mediated activation of Akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor. J Biol Chem. 2003 Oct 10; 278(41): 39830-8. [PubMed]
Kinsella MG, Tran PK, Weiser-Evans MC, Reidy M, Majack RA, Wight TN. Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):608-14. [PubMed]
Leon-Velarde F, McCullough RG, McCullough RE, Reeves JT; CMS Consensus Working Group. Proposal for scoring severity in chronic mountain sickness (CMS). Background and conclusions of the CMS Working Group. Adv Exp Med Biol. 2003;543:339-54. [PubMed]
Mateev S, Sillau AH, Mouser R, McCullough RE, White MM, Young DA, Moore LG. Chronic hypoxia opposes pregnancy-induced increase in uterine artery vasodilator response to flow. Am J Physiol Heart Circ Physiol. 2003 Mar;284(3):H820-9. [PubMed]
Mazzeo RS, Reeves JT. Adrenergic contribution during acclimatization to high altitude: perspectives from Pikes Peak. Exerc Sport Sci Rev. 2003 Jan;31(1):13-8. [PubMed]
McKean DM, Sisbarro L, Ilic D, Kaplan-Alburquerque N, Nemenoff R, Weiser-Evans M, Kern MJ, Jones PL. FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003 Apr 28; 161(2): 393-402. [PubMed]
Perlstein I, Connolly JM, Cui X, Song C, Li Q, Jones PL, Lu Z, DeFelice S, Klugherz B, Wilensky R, Levy RJ. DNA delivery from an intravascular stent with a denatured collagen-polylactic-polyglycolic acid-controlled release coating: mechanisms of enhanced transfection. Gene Ther. 2003 Aug; 10(17): 1420-8. [PubMed]
Stenmark KR, Gebb SA. Lung vascular development: breathing new life into an old problem. Am J Respir Cell Mol Biol. 2003 Feb;28(2):133-7. [PubMed]
Stiebellehner L, Frid MG, Reeves JT, Low RB, Gnanasekharan M, Stenmark KR. Bovine distal pulmonary arterial media is composed of a uniform population of well-differentiated smooth muscle cells with low proliferative capabilities. Am J Physiol Lung Cell Mol Physiol. 2003 Oct;285(4):L819-28. [PubMed]
Tock J, Van Putten V, Stenmark KR, Nemenoff RA. Induction of SM-alpha-actin expression by mechanical strain in adult vascular smooth muscle cells is mediated through activation of JNK and p38 MAP kinase. Biochem Biophys Res Commun. 2003 Feb 21;301(4):1116-21. [PubMed]
Walker HA, Whitelock JM, Garl PJ, Nemenoff RA, Stenmark KR, Weiser-Evans MC. Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling. Mol Biol Cell. 2003 May;14(5):1941-52. [PubMed]
2002
Ahmad S, Ahmad A, Gerasimovskaya E, Stenmark K, White CW. Hypoxia promotes survival of HLMVEC and A549 cells in hyperoxia by activating PI3K. FASEB J. 2002;16:A1169.
Ahmad S, Ahmad A, Gerasimovskaya E, Stenmark KR, White CW. Hypoxic preexposure enhances survival of lung epithelial cells in hyperoxia via PI3-K dependent pathway. Am J Resp Crit Care Med. 2002;165(8):A72.
Carpenter TC, Stenmark KR. Effects of hypoxia on the developing pulmonary circulation. In: Abman SH, Cherniak R, Haddad G, editors. Basic mechanisms of pediatric respiratory disease. Hamilton, Ont: BC Decker; 2002.
Carpenter TC. Corticosteroids in the treatment of severe mycoplasma encephalitis in children. Crit Care Med. 2002 Apr;30(4):925-7. [PubMed]
Das M, Dempsey EC, Reeves JT, Stenmark KR. Selective expansion of fibroblast subpopulations from pulmonary artery adventitia in response to hypoxia. Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L976-86. [PubMed]
Davie ND, Crossno JT Jr., Frid MG, Hofmeister SE, Gerasimovskaya EV, Hydes DM, McNiece I, Brunetti JA, Reeves JT, Stenmark KR. Adventitial neovascularization in hypoxic pulmonary hypertension: potential contribution of bone marrow-derived vascular progenitor cells. Mol Biol Cell. 2002:L283.
Dobyns EL, Anas NG, Fortenberry JD, Deshpande J, Cornfield DN, Tasker RC, Liu P, Eells PL, Griebel J, Kinsella JP, Abman SH. Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. Crit Care Med. 2002 Nov;30(11):2425-9. [PubMed]
Frid MG, Kale VA, Stenmark KR. Mature vascular endothelium can give rise to smooth muscle cells via endothelial-mesenchymal transdifferentiation: in vitro analysis. Circ Res. 2002 Jun 14;90(11):1189-96. [PubMed]
Gerasimovskaya E, Ahmad S, Ahmad A, White CW, Marusyk V, Stenmark KR. Phosphatidylinositol 3'-kinase (PI3-K) and mediates ATP-and hypoxia- induced proliferation of pulmonary artery adventitial fibroblasts. Am J Resp Crit Care Med. 2002;165(8):A361.
Gerasimovskaya E, Ahmad S, White C, Marusyk V, Stenmark K. Extracellular ATP plays an autocrine/paracrine role in hypoxia-induced adventitial fibroblasts growth. Am J Resp Crit Care Med. 2002,165(8):A361.
Gerasimovskaya EV, Ahmad S, White CW, Jones PL, Carpenter TC, Stenmark KR. Extracellular ATP is an atocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth. Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor. J Biol Chem. 2002 Nov 22;277(47):44683-50. [PubMed]
Gerasimovskaya EV, Ahmad S, White CW, Stenmark KR. P2Y and P2X purinoceptor activation is involved in an autocrine/paracrine loop of hypoxia-induced fibroblasts proliferation. Mol Biol Cell. 2002;13:15a.
Grover RF, Cruz JC, Grover EB, Reeves JT. Exercise-dependent ventilatory sensitivity to hypoxia in Andean natives. Respir Physiol Neurobiol. 2002 Oct 23;133(1-2):35-41. [PubMed]
Jones FS, McKean DM, Meech R, Edelman DB, Oakey RJ, Jones PL. Regulation of vascular smooth muscle cell growth and adhesion by paired-related homeobox genes. Chest. 2002 Mar;121(3 Suppl):S89-90. [PubMed]
Jones PL, Chapados R, Baldwin HS, Raff GW, Vitvitsky EV, Spray TL, Gaynor JW. Altered hemodynamics controls matrix metalloproteinase activity and tenascin-C expression in neonatal pig lung. Am J Physiol Lung Cell Mol Physiol. 2002 Jan;282(1):L26-35. [PubMed]
Li QY, Jones PL, Lafferty RP, Safer D, Levy RJ. Thymosin beta4 regulation, expression and function in aortic valve interstitial cells. J Heart Valve Dis. 2002 Sep;11(5):726-35. [PubMed]
Reeves JT. High adventure in pulmonary hypertension: acute and chronic hypoxia are not the same. Am J Respir Crit Care Med. 2002 Dec 15;166(12 Pt 1):1537-8. [PubMed]
Stenmark KR, Gerasimovskaya E, Namenoff RA, Das M. Hypoxic activation of adventitial fibroblasts: role in vascular remodeling. Chest. 2002 Dec;122(6 Suppl):326S-34. [PubMed]
Twite M. Intensive care of critically ill and injured children. In: Southall D, editor. International child health care: a practical manual for hospitals worldwide. London: BMJ Books; 2002.
Weir EK, Reeve HL, Reeves JT. Interactions of blood and the pulmonary circulation. Armonk, NY: Futura; 2002.
Young AJ, Reeves JT. Human adaptation to high terrestrial altitude. In: Pandolf KB, Burr RE, editors. Medical aspects of harsh environments. Washington DC: Borden Institute; 2002.
2001
Balasubramaniam V, Wagener JS. Review of Kendig's disorders of the respiratory tract in children. Respir Care. 2001 January;46(1):68-9.
Carpenter TC, Stenmark KR. Hypoxia decreases lung neprilysin expression and increases pulmonary vascular leak. Am J Physiol Lung Cell Mol Physiol. 2001 Oct;281(4):L941-8. [PubMed]
Das M, Bouchey DM, Moore MJ, Hopkins DC, Nemenoff RA, Stenmark KR. Hypoxia-induced proliferative response of vascular adventitial fibroblasts is dependent on g protein-mediated activation of mitogen-activated protein kinases. J Biol Chem. 2001 May 11;276(19):15631-40. [PubMed]
Jian B, Jones PL, Li Q, Mohler ER 3rd, Schoen FJ, Levy RJ. Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis. Am J Pathol. 2001 Jul;159(1):321-7. [PubMed]
Jones FS, Meech R, Edelman DB, Oakey RJ, Jones PL. Prx1 controls vascular smooth muscle cell proliferation and tenascin-C expression and is upregulated with Prx2 in pulmonary vascular disease. Circ Res. 2001 Jul 20;89(2):131-8. [PubMed]
Jones PL. Extracellular matrix and tenascin-C in pathogenesis of breast cancer. Lancet. 2001 Jun 23;357(9273):1992-4. [PubMed]
Kasaragod AB, Lucia MS, Cabirac G, Grotendorst GR, Stenmark KR. Connective tissue growth factor expression in pediatric myofibroblastic tumors. Pediatr Dev Pathol. 2001 Jan-Feb;4(1):37-45. [PubMed]
Klemm DJ, Watson PA, Frid MG, Dempsey EC, Schaack J, Colton LA, Nesterova A, Stenmark KR, Reusch JE. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J Biol Chem. 2001 Dec 7;276(49):46132-41. [PubMed]
Reeves JT, Stenmark KR. The pulmonary circulation at high altitude. In: Hornbein T, Schoene RB, editors. High altitude. An exploration of human adaptation. Lung biology in health and disease, v. 161. New York: Marcel Dekker; 2001.
Reeves JT, Zamudio S, Dahms TE, Asmus I, Braun B, Butterfield GE, McCullough RG, Muza SR, Rock PB, Moore LG. Erythropoiesis in women during 11 days at 4,300 m is not affected by menstrual cycle phase. J Appl Physiol. 2001 Dec;91(6):2579-86. [PubMed]
Robinson A, Fellows KE, Bridges ND, Rome JJ. Effectiveness of pharmacomechanical thrombolysis in infants and children. Am J Cardiol. 2001 Feb 15;87(4):496-9, A8. [PubMed]
Stenmark KR. Cell-, age-, and phenotype-dependent differences in the control of gene expression. Am J Physiol Lung Cell Mol Physiol. 2001 Oct;281(4):L762-5. [PubMed]
Upton PD, Wharton J, Coppock H, Davie N, Yang X, Yacoub MH, Ghatei MA, Polak JM, Bloom SR, Smith DM, Morrell NW. Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations. Am J Respir Cell Mol Biol. 2001 Feb;24(2):170-8. [PubMed]
Upton PD, Wharton J, Davie N, Ghatei MA, Smith DM, Morrell NW. Differential adrenomedullin release and endothelin receptor expression in distinct subpopulations of human airway smooth-muscle cells. Am J Respir Cell Mol Biol. 2001 Sep;25(3):316-25. [PubMed]
1999-2000
Abman SH, Dobyns EL, Kinsella JP. Role of inhaled nitric oxide in the treatment of children with severe acute hypoximic respiratory failure. New Horiz. 1999;7:386.
Belknap JK, Weiser-Evans MC, Grieshaber SS, Majack RA, Stenmark KR. Relationship between perlecan and tropoelastin gene expression and cell replication in the developing rat pulmonary vasculature. Am J Respir Cell Mol Biol. 1999 Jan;20(1):24-34. [PubMed]
Carpenter TC, Stenmark KR. Endothelin receptor blockade decreases lung water in young rats exposed to viral infection and hypoxia. Am J Physiol Lung Cell Mol Physiol. 2000 Sep;279(3):L547-L554. [PubMed]
Das M, Dempsey EC, Bouchey D, Reyland ME, Stenmark KR. Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes. Am J Respir Cell Mol Biol. 2000 Jan;22(1):15-25. [PubMed]
Dobyns EL. Pleural effusions and hypoxemia. Crit Care Med. 1999 Mar;27(3):472. [PubMed]
Dobyns EL, Cornfield DN, Anas NG, Fortenberry JD, Tasker RC, Lynch A, Liu P, Eells PL, Griebel J, Baier M, Kinsella JP, Abman SH. Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure. J Pediatr. 1999 Apr;134(4):406-12. [PubMed]
Dobyns EL, Durmowicz AG, Henry D, Loftness SL, Stenmark KR. Critical care. In: Hay WW Jr., Hayward AR, Levin MJ, Sondheimer JM, editors. Current pediatric diagnosis and treatment. 14th ed. Stamford, CT: Appleton and Lange; 1999. p. 316-40.
Dobyns EL, Eells PL, Griebel JL, Abman SH. Elevated plasma endothelin-1 and cytokine levels in children with severe acute respiratory distress syndrome. J Pediatr. 1999 Aug;135(2 Pt 1):246-9. [PubMed]
Dobyns EL, Griebel J, Kinsella JP, Abman SH, Accurso FJ. Infant lung function after inhaled nitric oxide therapy for persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 1999 Jul;28(1):24-30. [PubMed]
Durmowicz AG, Stenmark KR. Mechanisms of structural remodeling in chronic pulmonary hypertension. Pediatr Rev. 1999 Nov;20(11):e91-e102. [PubMed]
Frid MG, Aldashev AA, Nemenoff RA, Higashito R, Westcott JY, Stenmark KR. Subendothelial cells from normal bovine arteries exhibit autonomous growth and constitutively activated intracellular signaling. Arterioscler Thromb Vasc Biol. 1999 Dec;19(12):2884-93. [PubMed]
Gimbrone MA Jr, Anderson KR, Topper JN, Langille BL, Clowes AW, Bercel S, Davies MG, Stenmark KR, Frid MG, Weiser-Evans MC, Aldashev AA, Nemenoff RA, Majesky MW, Landerholm TE, Lu J, Ito WD, Arras M, Scholz D, Imhof B, Aurrand-Lions M, Schaper W, Nagel TE, Resnick N, Dewey CF, Gimbrone MA, Davies PF. Special communication of the critical role of mechanical forces in blood vessel development, physiology and pathology. J Vasc Surg. 1999 Jun;29(6):1104-51. [PubMed]
Guldemeester A, Stenmark KR, Brough GH, Stevens T. Mechanisms regulating cAMP-mediated growth of bovine neonatal pulmonary artery smooth muscle cells. Am J Physiol. 1999 Jun;276(6 Pt 1):L1010-7. [PubMed]
Higenbottam T, Stenmark K, Simonneau G. Treatments for severe pulmonary hypertension. Lancet. 1999 Jan 30;353(9150):338-40. [PubMed]
Kasaragod A, Lucia MS, Cabirac G, Grotendorst GR, Stenmark KR. Connective tissue growth factor expression in pediatric myofibroblastic tumors. Ped Devel Pathol. 2000. In press.
Kasaragod AB, Lucia MS, Lum GM, Caldwell S, Stork L, Stenmark KR. Solitary renal myofibromatosis: an unusual cause of infantile hypertension. Pediatrics. 1999 May;103(5):e66. [PubMed]
Kirchner K, Dobyns EL, Stenmark KR. Lung cell biology. In: Taussig LM, Landau LI, editors. Pediatric respiratory medicine. St. Louis: Mosby; 1999. p. 37-56.
Lane J, Khongphatthanayothin A, Luna C, Wong PC, Acherman R. Reverse aortic arch flow secondary to severe pulmonary hypertension. Am J Perinatol. 1999;16(3):143.
Lane J, Wong PC, Hohn A. Atrioventricular septal defects. In: Moller JH, Hoffman JIE, editors. Peditric cardiovascular medicine. New York: Churchill Livingstone; 2000.
Lemler MS, Bies RD, Frid MG, Sastravaha A, Zisman LS, Bohlmeyer T, Gerdes AM, Reeves JT, Stenmark KR. Myocyte cytoskeletal disorganization and right heart failure in hypoxia-induced neonatal pulmonary hypertension. Am J Physiol Heart Circ Physiol. 2000 Sep;279(3):H1365-76. [PubMed]
Leon-Velarde F, Reeves JT. International consensus group on chronic mountain sickness. Adv Exp Med Biol. 1999;474:351-3. [PubMed]
Morrell NW, Weiser MCM, Stenmark KR. Development of the pulmonary vasculature. In: Gaultier C, Bourbon JR, Post M, editors. Lung development. New York: Oxford University Press; 1999. p. 152-95.
Reeves JT. John Sutton and altitude research - A study in high energy, 1941-1996. In press.
Reeves JT. Lung arteriolar endothelial cell proliferation at birth: possible roles of stretch and hypoxia. In: Weir EK, Archer SL, Reeves JT, editors. The fetal and neonatal pulmonary circulations. Armonk, NY: Futura; 2000. p. 215-38.
Reeves JT. Why does the exercise cardiac output fall during altitude residence and is it important? Adv Exp Med Biol. 1999;474:335-50. [PubMed]
Reeves JT, Grover RF. High minded medical scientist. In press.
Rock PB, Muza SR, Fulco CS, Beidleman BA, Cymerman A, Braun B, Zamudio S, Mawson JT, Dominick SB, Reeves JT, Butterfield GE, Moore LG. Effect of menstrual cycle on incidence of acute mountain sickness in women: preliminary results for two studies. In press.
Schwarz MA, Zhang F, Lane J, Schachtner S, Jin Y, Deutsch G, Starnes V, Pitt BR. Angiogensis and morphogenesis of murine fetal distal lung in an allograft model. Am J Physiol Lung Cell Mol Physiol. 2000;278:L100.
Simoes EA, Hayward AR, Ponnuraj EM, Straumanis JP, Stenmark KR, Wilson HL, Babu PG. Respiratory syncytial virus infects the Bonnet monkey, Macaca radiata. Pediatr Dev Pathol. 1999 Jul-Aug;2(4):316-26. [PubMed]
Stenmark KR. New hope for the treatment of pulmonary hypertension: novel approaches to a complex disease. Ped Res. 2000;48:421.
Stenmark KR, Bouchey D, Nemenoff R, Dempsey EC, Das M. Hypoxia-induced pulmonary vascular remodeling: contribution of the adventitial fibroblasts. Physiol Res. 2000;49(5):503-17. [PubMed]
Stenmark KR, Frid M, Nemenoff R, Dempsey EC, Das M. Hypoxia induces cell-specific changes in gene expression in vascular wall cells: implications for pulmonary hypertension [review]. Adv Exp Med Biol. 1999;474:231-58. [PubMed]
Tomlinson LA, Carpenter TC, Baker EH, Bridges JB, Weil JV. Hypoxia reduces airway epithelial sodium transport in rats. Am J Physiol. 1999 Nov;277(5 Pt 1):L881-6. [PubMed]
Weir EK, Archer SL, Reeves JT, editors. The fetal and neonatal pulmonary circulations. Armonk, NY: Futura; 2000.
Weiser-Evans MC, Quinn BE, Burkard MR, Stenmark KR. Transient reexpression of an embryonic autonomous growth phenotype by adult carotid artery smooth muscle cells after vascular injury. J Cell Physiol. 2000 Jan;182(1):12-23. [PubMed]
Weiser-Evans MC, Schwartz PE, Grieshaber NA, Quinn BE, Grieshaber SS, Belknap JK, Mourani PM, Majack RA, Stenmark KR. Novel embryonic genes are preferentially expressed by autonomously replicating rat embryonic and neointimal smooth muscle cells. Circ Res. 2000;87:608-15.
Weiser-Evans MC, Stenmark KR. Perlecan heparan sulfates in the control of vascular smooth muscle cell proliferation. In: Weir EK, Archer SL, Reeves JT, editors. The fetal and neonatal pulmonary circulations. Armonk, NY: Futura; 2000. p. 149-70.
1997-1998
Aldashev AA, Frid MG, Nemenoff RA, Stenmark KR. Secretion of a novel mitogenic factor by a unique population of bovine arterial smooth muscle cells. ATS: Am J Respir Crit Care Med 1997;155(4):A636.
Arnold M, Holcomb S, Reeves CS, Reeves JT, Zaremba EF. Patients in the L'viv Oblast want health education: a potential role for family physicians. Pract Med 1997;3-4:114-8.
Arnold M, Holcomb S, Reeves CS, Reeves JT, Zaremba EF. Emotional health in the L'viv Oblast: a potential role for family physicians. Pract Med 1997. In press.
Asano K, Mazzeo RS, McCullough RE, Wolfel EE, Reeves JT. Relation of sympathetic activation to ventilation in man at 4,300 m altitude. Aviat Space Environ Med 1997;68:104-10.
Belknap JK, Orton EC, Ensley B, Stenmark KR. Hypoxia increases romodeoxyuridine labeling indices in bovine neonatal pulmonary arteries. Am J Respir Cell Mol Biol 1997;16:366-71.
Brooks GA, Butterfield GE, Roberts AC, Wolfel EE, Reeves JT. Substrate utilization at altitude. In press.
Cabirac GF, Frid MG, Aldashev AA, Grotendorst GF, Mecham RP, Stenmark KR. Expression of connective tissue growth factor by specific cell populations of the pulmonary arterial media. ATS: Am J Respir Crit Care Med 1998;157(3):A210.
Carpenter TC, Niermeyer S, Durmowicz AG. Altitude-related illness in children. Curr Probl Pediatr 1998;28:177-204.
Carpenter TC, Reeves JT, Durmowicz AG. Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema. J Appl Physiol 1998;84:1048-54.
Carpenter TC, Reeves JT, Durmowicz AG. Lung neutral endopeptidase activity is reduced in young rats exposed to viral infection and hypoxia. Am J Respir Crit Care Med 1998;157:A529.
Carpenter TC, Reeves JT, Durmowicz AG. Respiratory viral infection increases susceptibility to hypoxia-induced pulmonary interstitial edema in young rats. Am J Respir Crit Care Med 1997;155:A684.
Carpenter TC, Reeves JT, Durmowicz AG. Respiratory viral infection increases susceptibility to hypoxia-induced pulmonary interstitial edema in young rats. J Appl Physiol 1998;84:1048-54.
Carpenter TC, Stenmark KR. Lack of benefit from high-dose epinephrine in pediatric in-hospital cardiopulmonary arrest. Pediatrics 1997;99:403-8.
Das M, Bouchey D, Dempsey EC, Stenmark KR. Pulmonary hypertension-induced changes in growth properties of adventitial fibroblasts. ATS: Am J Respir Crit Care Med 1998;157(3):A589.
Das M, Dempsey EC, Stenmark KR. Selective subpopulations of pulmonary artery adventitial fibroblasts exhibit unique proliferative and apoptotic capabilities. FASEB J 1998;12(4):A339.
Das M, Dempsey EC, Stenmark KR. Vascular wall remodeling during hypoxia-induced pulmonary hypertension is determined by a balance between proliferation and apoptosis. Presented at: The Xth International Vascular Biology Meeting; 1998; Australia.
Das M, Stenmark KR, Ruff LJ, Dempsey EC. Selected isozymes of PKC contribute to Das augmented growth of fetal and neonatal bovine pulmonary artery. Am J Physiol 1997;273:L1276-L1284.
Das M, Stenmark KR, Dempsey EC. Hypoxia stimulates growth of selective subsets of pulmonary artery adventitial fibroblasts. FASEB J 1997;11:A557.
Das M, Stenmark KR, Ruff LJ, Dempsey EC. Enhanced growth of immature bovine pulmonary artery adventitial fibroblasts is dependent on the calcium-regulated a and bII isozymes of protein kinase C. Am J Respir Crit Care Med 1997;155:A637.
Das M, Stenmark KR, Ruff LJ, Dempsey EC. The Ca2+-dependent isozymes of protein kinase C are uniquely important in the enhanced growth of immature adventitial fibroblasts isolated from the bovine pulmonary arterial wall at a time of heightened susceptibility to vascular injury. Chest 1998;114:68S-69S.
Das M, Stenmark KR, Dempsey EC. Hypoxia stimulates growth of selective subsets of pulmonary artery adventitial fibroblasts. FASEB J 1997;11(3):A557.
Das M, Stenmark KR, Ruff LJ, Dempsey EC. Selected isozymes of PKC contribute to augmented growth of fetal and neonatal bovine pulmonary artery fibroblasts. Am J Physiol: Heart Lung 1997;273:L1276-L1284.
Das M, Stenmark KR, Ruff LJ, Dempsey EC. Enhanced growth of immature bovine pulmonary artery adventitial fibroblasts is dependent on the calcium-regulated a and bII isozymes of protein kinase C. ATS: Am J Resp Crit Care Med 1997;155(4):A637.
Dempsey EC, Das M, Frid MG, Xu Y, Stenmark KR. Hypoxic growth of bovine pulmonary artery smooth muscle cells is dependent on synergy, heterogeneity, and injury-induced phenotypic change. Chest 1998; 114:29S-30S.
Dempsey EC, Frid MG, Aldashev AA, Stenmark KR. Heterogeneity in the proliferative response of bovine pulmonary artery smooth muscle cells to mitogens and hypoxia: importance of protein kinase C-a1. Can J Physiol Pharmacol 1997;75:936-44.
Dobyns EL, Durmowicz AG, Henry D, Loftness SL, Stenmark KR. Critical care. In: Hay WW Jr., Groothuis JR, Hayward AR, Levin MJ, editors. Current pediatric diagnosis and treatment. 13th ed. Norwalk: Appleton and Lange; 1997.
Durmowicz AG, Chetham PM, Carpenter TC, Weil JV. Quabain augments hypoxia induced pulmonary edema in young rats. FASEB J 1997;11:A560.
Durmowicz AG, Frid MG, Stenmark KR. Regulation of pulmonary vascular elastogenesis. Presented at: The Critical Care Symposium 1997, Society for Critical Care Medicine; 1997; Anaheim CA.
Durmowicz AG, Noordeweir E, Nicholas R, Reeves JT. Inflammatory processes may predispose children to develop high altitude pulmonary edema. J Pediatr 1997;30:838-40.
Durmowicz AG, Stenmark KR. Acute respiratory failure. In: Chernick V, Boat TF, editors. Kendig's disorders of the respiratory tract in children. 6th ed. Philadelphia: W.B. Saunders; 1998. p. 265-83.
Frid MG, Aldashev AA, Dempsey EC, Stenmark KR. Smooth muscle cells isolated from discrete compartments of the mature vascular media exhibit unique phenotypes and distinct growth capabilities. Circ Res 1997;81:940-52.
Frid MG, Aldashev AA, Cabirac GF, Dempsey EC, Stenmark KR. Hypoxia stimulates proliferation of a unique cell population isolated from the bovine vascular media. Chest 1998;114:28S-29S.
Frid MG, Dempsey EC, Durmowicz AG, Stenmark KR. Smooth muscle cell heterogeneity in pulmonary and systemic vessels: importance in vascular disease. Arterioscler Thromb Vasc Biol 1997;17:1203-9.
Frid MG, Higashito R, Nemenoff RA, Stenmark KR. Unique arterial smooth muscle cell subpopulations exhibit heightened proliferative response to hypoxia via activation of mitogen-activated protein kinase signaling pathway(s). Presented at: The Xth International Vascular Biology Meeting; 1998; Cairns Australia.
Frid MG, Higashito R, Nemenoff RA, Stenmark KR. Hypoxia induces proliferation in specific arterial cell subpopulations via activation of mitogen activated protein kinase (MAPK) signaling pathway(s). ATS: Am J Respir Crit Care Med 1998;157(3):A208.
Grover RF, Reeves, JT, Selland MA, McCullough RG, Dahms TE, Wolfel EE, Greenleaf JE. b-adrenergic blockade does not prevent polycythemia or decrease in plasma volume in men at 4300 m altitude. Europ J Appl Physiol 1997;77:264-70.
Guldemeester HA, Babal P, Stenmark KR, Brough G, Stevens T. Expression pattern of adenylyl cyclase isoforms unmasks different cell populations in the pulmonary artery media of neonatal lung. ATS: Am J Respir Crit Care Med 1998;157(3):A211.
Morrell NW, Danilov SM, Satyan KR, Morris KG, Stenmark KR. Right ventricular angiotensin converting enzyme activity and expression is increased during hypoxic pulmonary hypertension. Cardiovasc Res 1997;34:393-403.
Morrell NW, Stenmark KR. Angiotensin II stimulates proliferation of rat pulmonary microvascular smooth muscle cells. ATS: Am J Respir Crit Care Med 1997;155(4):A636.
Morrell NW, Weiser MCM, Stenmark KR. Developmental aspects of pulmonary arterial endothelial and smooth muscle cells. In: Gaultier C, Post M, editors. Lung development. New York: Oxford University Press; 1998.
Reeves JT. Literary gems. Lincoln Center MA: The Cottage Press; 1998.
Reeves JT, Carl J. Wiggers and the pulmonary circulation: a young man in search of excellence. Am J Physiol 1998;274(18):L467-L474.
Reeves JT, Grover RF. High minded medical scientist. In press.
Reeves JT, Rubin LJ. The pulmonary circulation: snapshots of progress. Am J Respir Crit Care Med 1998;157:S101-S108.
Reeves JT, Sutton J. Altitude research - a study in high energy, 1941-1996. In press.
Reeves JT, Stenmark KR. The pulmonary circulation at high altitude. In: Hornbein T, Schoene R, Lenfant C, editors. High altitude, lung biology in health and disease. New York: Marcel Dekker. In press.
Rock PB, Muza SR, Fulco CS, Beidleman BA, Cymerman A, Braun B, Zamudio S, Mawson JT, Dominick SB, Reeves JT, Butterfield GE, Moore LG. Effect of menstrual cycle on incidence of acute mountain sickness in women: preliminary results for two studies. In press.
Stenmark KR, Frid MG. Smooth muscle cell subpopulations in pulmonary vascular disease: role of specific SMC subpopulations in pulmonary vascular disease. Chest 1998;114:82S-90S.
Stenmark KR, Mecham RP. Cellular and molecular mechanisms of pulmonary vascular remodeling. Ann Rev Physiol 1997;59:89-144.
Stiebellehner, L, Belknap JK, Ensley B, Tucker, A, Orton EC, Reeves JT, Stenmark KR. Lung endothelial cell proliferation in normal and pulmonary hypertensive neonatal calves.
Am J Physiol. 1998 Sep;275(3 Pt 1):L593-600.
Stiebellehner L, Belknap J, Ensley B, Tucker A, Orton EC, Reeves JT, Stenmark KR. Post-natal decrease in arteriolar replication of calves' lung endothelium is inhibited by hypoxia. ATS: Am J Respir Crit Care Med 1998;157(3):A208.
Stiebellehner L, Ferguson MF, Frid MG, Stenmark KR. Comparative analysis of the growth characteristics of smooth muscle cells isolated from the proximal and distal bovine pulmonary artery. ATS: Am J Respir Crit Care Med 1997;155(4):A636.
Stiebellehner L, Gnanasekharan M, Frid M, Low RB, Stenmark KR. Smooth muscle myosin heavy chain SM-B isoform expression is increased in newly muscularized arteries of patients and animals with severe pulmonary hypertension. ATS: Am J Respir Crit Care Med 1998;157(3):A589.
Tottempudi P, Reyland ME, Das M, Hoagland KD, Dempsey EC. Regulation of protein kinase C-a gene expression in bovine pulmonary artery smooth muscle cells. FASEB J 1998;12:2753.
Wang NP, Wan BC, Skelly M, Frid MG, Glukhova MA, Koteliansky VE, Gown, AM. Antibodies to novel myoepithelium-associated proteins distinguish benign lesions and in-situ-carcinoma from invasive carcinoma of the breast. Appl Immunohistochem . 1997; 5:141-51.
Weir EK, Reeves JT. Pulmonary edema. American heart monograph. Armonk, NY: Futura Publishing Company; 1998. Weiser MCM. Transient reiteration of autonomous growth capabilities in adult smooth muscle cells following experimental vascular injury. Circulation 1997;96(8):I-667.
Weiser MCM, Schwartz PE, Grieshaber NA, Majack RA. Perlecan heparan sulfates regulate Oct-1 gene expression in vascular smooth muscle cells. Mol Biol Cell 1997;8:999-1011.
Weiser MCM, Quinn BE, Stenmark KR. SMC: Basement membrane interactions suppress integrin-activated growth-promoting intracellular signaling pathways. ATS: Am J Respir Crit Care Med 1998;157(3):A268.
Weiser MCM, Quinn BE, Stiebellehner L, Belknap JK, Stenmark KR. Hypoxia exposure interrupts the expression of the SMC growth inhibitor, perlecan, by PA SMC. ATS: Am J Respir Crit Care Med 1998;157(3):A268.
Weiser-Evans MCM, Quinn BE, Stenmark KR. Integrin-activated growth-promoting signaling pathways are suppressed by perlecan-rich basement membranes in non-autonomously, but not in autonomously, replicating SMC. Presented at: The Xth International Vascular Biology Meeting; 1998; Cairns Australia.
White MM, Horan MP, Le Cras TD, Weiser MCM, Stenmark KR, Abman SH, Perryman B, Moore LG. Pregnancy increases and chronic hypoxia decreases endothelial nitric oxide synthase (eNOS) protein expression in guinea pig uterine arteries (UA). FASEB J 1997;11(3):A479.
Xu Y, Stenmark KR, Das M, Walchak SJ, Ruff LJ, Dempsey EC. Pulmonary artery smooth muscle cells from chronically hypoxic neonatal calves retain fetal-like and acquire new growth properties. Am J Physiol 1997;273(17):L234-L245.
Yu AY, Frid MG, Shimoda LA, Siener CM, Stenmark KR, Semenza GA. Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor1 in the lung. Am J Physiol. Am J Physiol 1998 Oct;275(4 Pt 1):L818-26.
|
|
