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Developmental and Behavioral Pediatrics
Research
The Child
Development Unit (CDU) at The Children’s Hospital was awarded a grant by Autism Speaks to become an Autism Treatment Network (ATN) site in January 2008. We are part of a multisite network of fifteen programs dedicated to improving medical care for children with autism spectrum disorders (ASD). As part of the ATN, our patients with ASD are eligible to be entered into a registry designed to track co-occurring medical and psychiatric conditions and treatments. Over the next year we will begin two new studies in collaboration with four other sites as part of ATN: one study will evaluate nutrition in children with ASD, and one will compare two methods of education about sleep hygiene in children with ASD. We also participate in a multisite, case-cohort study of the etiology of autism, which is funded by the CDC.
The eXtraordinarY Kids Clinic has a grant to evaluate genotype-phenotype correlations in individuals with sex chromosome aneuploidy and will establish a repository of DNA for future genetic studies. We will also study the behavioral and motor effects of testosterone replacement therapy in adolescent males with XXY and XXYY syndromes.
We are a member of the National Fragile X Foundation’s Fragile X Clinical and Research Consortium, which was recently funded by the CDC to develop a registry of subjects with Fragile X for the purpose of tracking medical and behavioral features and to facilitate future clinical trials.
Drs. Reynolds and Tartaglia are also members of the Intellectual and Developmental Disabilities Research Center (IDDRC) faculty.
Faculty Research Interests
Dr. William Campbell has interests in early identification, diagnosis, and treatment of developmental disorders, particularly autism and related disorders. He serves as medical consultant for Early Intervention Colorado within the Colorado Department of Human Services, Division for Developmental Disabilities. Dr. Edward Goldson has interests in the clinical care of children with special health care needs. His research focus most recently has been in the area of autism and Down syndrome. In the past, although these are continued interests, he has done work in Fragile X and newborn follow-up. Dr. Ann Reynolds has interests in research related to sleep, nutrition, and gastrointestinal disorders in children with autism spectrum disorders. Dr. Nicole Tartaglia has ongoing research projects addressing the clinical phenotype of children with sex chromosome variations and will begin a project in the next year to evaluate the impact of testosterone replacement on executive function and behavior in individuals with Klinefelter’s syndrome.
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