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Neonatology
Research
The research interests and expertise of various faculty have fostered programmatic areas of excellence in pulmonary hypertension of the newborn at The Children's Hospital and in the study of metabolism of the very premature infant at University of Colorado Hospital. New areas of research interest include the use of stable isotopes and indirect calorimetry to study glucose and amino acid utilization in the premature infant, use of nitric oxide in the term and preterm infant and cardiopulmonary adaptation to altitude.
Faculty are also involved in basic research at the molecular, cellular, organ and whole animal levels. Areas of excellence include research on carbohydrate and amino acid metabolism and on organ blood-flow regulation. In vivo studies emphasizing chronically catheterized animals take place at the University of Colorado School of Medicine Perinatal Research Center. Areas of research interest include placental, cerebral, hepatic and muscle metabolism in normal, growth-retarded and hypoxic fetal lambs. Studies requiring stable isotopic analysis are completed in collaboration with Dr. Paul V. Fennessey in the Mass Spectrometry Core Laboratory. In vitro studies currently focus on growth-factor regulation and placental development under conditions of placental insufficiency.
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