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Child Neurology
Research Funding
(listed alphabetically by Principal Investigator or by Section faculty member involved)

2006-2008

Autism Treatment Network-Sponsored Multidisciplinary Clinic
Consultant: Timothy A. Benke, MD, PhD
Source: Autism Treatment Network
Amount: $50,000/yr
Term: 2008 - 2010

Impact of Early-Life Seizures on Glutamate Receptors and Synaptic Function
Principal Investigator: Timothy A. Benke, MD, PhD
Source: Klingenstein Fellowship
Amount: $75,000/yr
Term: 2008 - 2011

Impact of Early-Life Seizures on Glutamate Receptors and Synaptic Function
Principal Investigator: Timothy A. Benke, MD, PhD
Source: NINDS, NIH - 1 K02 NS056090-01A1
Amount: $187,380
Term: 2007 - 2012

Impact of Early-Life Seizures on Synaptic Plasticity
Principal Investigator: Timothy A. Benke, MD, PhD
Source: NINDS, NIH - K08 NS41267-02
Amount: $522,720
Term: 2002 - 2006

Neurotransmission at the Vestibular Calyx Synapse
Principal Investigator: Katherine J. Rennie, PhD
Co-Principal Investigator: Timothy A. Benke, MD, PhD
Source: National Institute on Deafness and Other Communication Disorders, NIH - 5R01DC008297-02
Amount: $170,000/yr
Term: 2007 - 2012

Validation of the Pediatric NIH Stroke Scale in Children
Principal Investigator: Rebecca Ichord, MD
Co-Investigator: Timothy J. Bernard, MD
Source: NINDS, NIH - C007-1060
Amount: $10,000/yr
Term: 2008 - 2009

A 16-Week, Randomized, Double-Blind, Placebo-Controlled Evaluation of the Efficacy, Tolerability, and Safety of Memantine Hydrochloride on Enhancing the Cognitive Abilities of Young Adults with Down Syndrome
Principal Investigator: Alberto Costa, MD, PhD
Co-Principal Investigator: Richard Boada, PhD
Source: Forest Laboratories, Inc.
Amount: $200,000/yr
Term: 2008 - 2009

The Linguistic Phenotype in Familial Dyslexia
Principal Investigator: Bruce F. Pennington, PhD
Co-Principal Investigator: Richard Boada, PhD
Source: NICHD, NIH - HD049027
Amount: $57,109/yr
Term: 2004 - 2009

GABA(A) Receptor Subunit Regulation in Epileptogenesis
Principal Investigator: Amy R. Brooks-Kayal, MD
Source: NINDS, NIH - R01 NS051710-05
Amount: $235,350
Term: 2005 - 2009

GABA(A) Receptors in Developmental Epileptogenesis
Principal Investigator: Amy R. Brooks-Kayal, MD
Source: NINDS, NIH - R01 NS38595-11
Amount: $180,653
Term: 2004 - 2009

Molecular Determinants of GABAR Gene Regulation
Principal Investigator: Shelley J. Russete
Co-Principal Investigator: Amy R. Brooks-Kayal, MD
Source: NINDS, NIH - R01 NS050393-03
Amount: $242,578
Term: 2006 - 2011

NICHQ (National Initiative for Children’s Healthcare Quality): Improving the System of Care for Children and Youth with Special Health Care Needs: Epilepsy and the Newborn Hearing Screening Programs Learning Collaborative
Consultant: Carolyn L. Green, MD
Source: Maternal and Child Health Bureau and Epilepsy Foundation of America
Amount: $25,000
Term: 2009

Pathologic Drooling in Pediatric Patients 3 to 18 Years of Age with Cerebral Palsy or Other Neurologic Conditions
Principal Investigator: Carolyn L. Green, MD
Source: Sciele Pharmaceuticals - SC-GLYCO-06-01/HZ1604/OCR6071
Amount: $13,000
Term: 2006 - 2008

Early Identification of Cognitive Deficits in Children with Neurofibromatosis Type I
Principal Investigators: Kathryn North, MD, and Jennifer Janusz, PsyD
Source: Department of Defense Grant - NF030015
Amount: $1,101,272
Term: 2004 - 2008

Cerebral Impact of Childhood Sleep Apnea
Principal Investigator: Ann Halbower, MD
Co-Principal Investigator: Jennifer Janusz, PsyD
Source: NIH - K23 RR024257
Amount: $750,000
Term: 2007 - 2012

Outcome Measurement of mTBI in Children and Adolescents
Principal Investigator: Gerard Gioia, PhD
Co-Investigator: Jennifer Janusz, PsyD
Source: CDC - U17/CCU323352-01
Amount: $2,000,000
Term: 2003 - 2007

Functional Magnetic Resonance Imaging in Children with Attention-Deficit Hyperactivity Disorder and Neurofibromatosis Type 1: A Pilot Study
Principal Investigator: Tena Rosser, MD
Co-Investigator: Jennifer Janusz, PsyD
Source: Research Advisory Council, Children’s National Medical Center
Amount: $30,000
Term: 2004 - 2006

Childhood Absence Epilepsy: Rx, PK-PD-Pharmacogenetics
Principal Investigator: Paul M. Levisohn, MD
Source: NIH - R01 NS045911-01A1 and NS045803
Amount: $134,000
Term: 2003 - 2008

Double-Blind Study of Clobazam for Lennox Gastaut Syndrome
Principal Investigator: Paul M. Levisohn, MD
Source: Ovation Pharmaceuticals, Inc.
Amount: Per patient enrolled
Term: 2008 - present

The Tuberous Sclerosis Natural History Database Project
Principal Investigator: Paul M. Levisohn, MD
Co-Principal Investigator: Dee A. Daniels, MSN, RN, CPNP
Source: National Tuberous Sclerosis Association
Amount: $30,000/yr
Term: 2008 - 2009

Axert Adolescent Migraine Study (CAPPS Migraine)
Principal Investigator: Tonia M. Sabo-Graham, MD
Source: Ortho McNeil
Amount: $10,654/yr
Term: 2007 - 2008

Depakote ER Migraine Study
Principal Investigator: Tonia M. Sabo-Graham, MD
Source: Abbott Laboratories
Amount: $2,492/yr
Term: 2006 - 2007

Pilot Study to Define Nutritional Interrrelationships of COQ10 and Magnesium in the Evaluation and Treatment of Childhood Migraine Headaches
Principal Investigator: Tonia M. Sabo-Graham, MD
Source: TCH Research Institute; TCH Clinical Translational Research Center - M01-RR 00069
Amount: Per patient enrolled
Term: 2008 - 2010

TXA-Adolescent Headache Study
Principal Investigator: Tonia M. Sabo-Graham, MD
Source: GlaxoSmithKline
Amount: $31,705/yr
Term: 2007 - 2009

Development of Positive Feedback During Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: NINDS, NIH - R01 NS34360-06
Amount: $1,270,668
Term: 2005 - 2009

Linking Synaptic Properties to Neural Network Operation
Principal Investigator: Kevin J. Staley, MD
Source: NINDS, NIH - R01 NS34700-11
Amount: $1,424,624
Term: 2004 - 2008

Mechanisms of Neuronal Chloride Accumulation
Principal Investigator: Kevin J. Staley, MD
Source: NINDS, NIH - R01 NS40109-04
Amount: $1,666,653
Term: 2005 - 2010

Progression of Temporal Lobe Epilepsy
Principal Investigator: F. Edward Dudek, MD
Co-Principal Investigator: Kevin J. Staley, MD
Source: NINDS, NIH - R01 NS045144-01
Amount: $103,950
Term: 2005 - 2006

Neuroprotection in an Animal Model of Neonatal Hypoxia-Ischemia
Principal Investigator: Andrew M. White, MD, PhD
Source: NINDS, NIH - 5 K08 NS053610-02
Amount: $173,340/yr
Term: 2006 - 2011

Children's Absence Epilepsy
Consultant: Greta N. Wilkening, PsyD
Source: NINDS, NIH - U01 N54591
Amount: $10,000/yr
Term: 2006 - 2015

Longitudinal Follow-Up of Children and Adults with Urea Cycle Disorders
Principal Investigator: Renata Gallagher, MD, PhD
Co-Principal Investigator: Greta N. Wilkening, PsyD
Source: Rare Disease Research Center and TCH Research Institute
Amount: $5,000
Term: 2008 - 2009

Antidepressant Effects on Spontaneous CA3 Population Bursts
Principal Investigator: Audrey S. Yee, MD
Source: Epilepsy Foundation of America - 200702-227
Amount: $50,000
Term: 2007 - 2008

Cellular Mechanisms of PLEDS
Principal Investigator: Audrey S. Yee, MD
Source: NINDS, NIH - 5 K08 NS047215-05
Amount: $798,250
Term: 2004 - 2008

Epilepsy and the Wnt-Signaling Pathway
Principal Investigator: Audrey S. Yee, MD
Co-Principal Investigator: Amy S. Yee, PhD
Source: Citizens United for Research in Epilespy (CURE)
Amount: $100,000/yr
Term: 2008 - 2009


2005

Impact of Early-Life Seizures on Synaptic Plasticity
Principal Investigator: Timothy A. Benke, MD, PhD
Source: National Institutes Health, National Institute of Neurological Disorders and Stroke - K08 NS41267-02
Amount: $522,720
Term: 2002-2006

Childhood Absence Epilepsy: Rx, PK-PD-Pharmacogenetics (Protocol No. R01NS045911-01A1)
Principal Investigator: Paul M. Levisohn, MD
Source: National Institutes of Health - NS 045911 and NS045803
Term: 2003-2008

A Multicenter, Open-Label, Long-Term, Follow-Up Study of the Safety and Efficacy of Levetiracetam in Children with Partial Onset Seizures (Protocol No. N01148)
Principal Investigator: Paul M. Levisohn, MD
Source: UCB Pharma, Inc.
Term: 2004-2005

A 19-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Safety Study to Evaluate the Cognitive and Neurophychological Effects of Levetiracetam 20-60 mg/kg/day, Divided in Twice Daily Dosing, as Adjunctive Treatment in Children 4-16 Years Old, Inclusive, with Refractory Partial Onset Seizures (Protocol No. N01103)
Principal Investigator: Paul M. Levisohn, MD
Source: UCB Pharma, Inc.
Term: 2004-2005

An Open-Label Multicenter Study of the Long-Term Safety of Depakote Sprinkle Capsules in the Treatment of Partial Seizures in Children (Protocol No. M04-714)
Principal Investigator: Paul M. Levisohn, MD
Source: Abbott Laboratories
Term: 2005

A Randomized, Double-Blind, Placebo-Controlled, Fixed Dose-Ranging Study to Assess the Safety, Tolerability, and Efficacy of Topirimate Oral Liquid and Sprinke Formulations as an Adjuct to Concurrent Anticonvulsant Therapy for Infants 1 to 23 Months of Age (Protocol No. TOPMAT-PEP-3001)
Principal Investigator: Paul M. Levisohn, MD
Source: Johnson & Johnson Pharmaceutical Research & Development, LLC
Term: 2005

The Linguistic Phenotype in Familial Dyslexia
Principal Investigator: Bruce F. Pennington, PhD
Co-Investigator: Richard Boada, PhD
Source: National Institutes of Child Health and Human Development - HD049027
Amount: $57,781/yr
Term: 2005-2009

Development of Positive Feedback During Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institutes of Neurological Disorders and Stroke - R01 NS34360-06
Amount: $1,270,668
Term: 2005-2009

Progression of Temporal Lobe Epilepsy
Principal Investigator: F. Edward Dudek, MD
Co-Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institutes of Neurological Disorders and Stroke - R01 NS045144-01
Amount: $103,950
Term: 2005-2006

Linking Synaptic Properties to Neural Network Operation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institutes of Neurological Disorders and Stroke - R01 NS34700-11
Amount: $1,424,624
Term: 2004-2008

Mechanisms of Neuronal Chloride Accumulation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institutes of Neurological Disorders and Stroke - R01 NS40109-04
Amount: $1,666,653
Term: 2005-2010

Bike for Hope
Principal Investigator: Brian S. Tseng, MD, PhD
Source: Sharp Family
Amount: $5,000
Term: 2005

Hike for Hope
Principal Investigator: Brian S. Tseng, MD, PhD
Source: Sharp Family
Amount: $25,000
Term: 2005

Cellular Mechanisms of PLEDS
Principal Investigator: Audrey S. Yee, MD
Source: National Institutes of Neurological Disorders and Stroke
Amount: $172,422/yr
Term: 2004-2009


2003-2004

Impact of Early-Life Seizures on Synaptic Plasticity
Principal Investigator: Timothy A. Benke, MD, PhD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - K08 NS41267-02
Amount: $522,720
Term: 2002-2006

Childhood Absence Epilepsy Treatment, PK-PD Pharmacogenetics
Principal Investigator: Paul M. Levisohn, MD
Source: National Institutes of Health, National Institute of Neurologic Disease and Stroke
Amount: $37,932/yr
Term: 2003-2008

Effect of Vagus Nerve Stimulator on Health-Related Quality of Life in Children with Medically Uncontrolled Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: Cyberonics
Amount: $20,000/yr
Term: 2000-2003

Development of Positive Feedback During Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - 3 R01 NS 34360
Amount: $403,297/yr
Term: 1996-2005

Linking Synaptic Properties to Neuronal Network Operation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - 5 R01 NS 34700
Amount: $345,653/yr
Term: 1995-2004


2001-2002

Impact of Early-Life Seizures on Synaptic Plasticity
Principal Investigator: Timothy A. Benke, MD, PhD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - K08 NS41267-02
Amount: $522,720
Term: 2002-2006

Double-Blind, Placebo-Controlled Trial of Vitamin E as Add-On Therapy for Children with Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: The Children's Hospital Research Institute Pilot Grant
Amount: $30,000
Term: 2000-2001

Effect of Vagus Nerve Stimulator on Health-Related Quality of Life in Children with Medically Uncontrolled Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: Cyberonics
Amount: $20,000/yr
Term: 2000-2003

Development of Positive Feedback During Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - 3 R01 NS 34360
Amount: $403,297/yr
Term: 1996-2005

Fellowship Training for Andrew White, MD
Principal Investigator: Kevin J. Staley, MD
Source: Epilepsy Foundation
Amount: $40,000
Term: 2000-2001

Linking Synaptic Properties to Neuronal Network Operation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - 5 R01 NS 34700
Amount: $345,653/yr
Term: 1995-2004


1999-2000

A Double-Blind Study of Valpiroate vs. LAMICTAL
Principal Investigator: Paul M. Levisohn, MD
Source: Glaxo-Wellcome, Inc.
Amount: $48,636
Term: 1996-1999

Effect of Topiramate on Spike-Wave Activity on the EEG in Patients with Primary Generalized Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: Ortho-McNeil Pharmaceutical, Inc.
Amount: $15,876
Term: 2000

Double-Blind Placebo-Controlled Trial of Vitamin E as Add-On Therapy for Children with Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: The Children's Hospital Research Institute Pilot Grant
Amount: $30,000
Term: 2000-2001

Effect of Vagus Nerve Stimulator on Health-Related Quality of Life in Children with Medically Uncontrolled Epilepsy
Principal Investigator: Paul M. Levisohn, MD
Source: Cyberonics
Amount: $20,000
Term: 2000-2001

Establishment of the Ketogenic Diet Center at The Children's Hospital
Principal Investigator: Paul M. Levisohn, MD
Source: The Children's Hospital Foundation and The Campbell Family and Friends
Amount: $150,000
Term: 1998-2000

Neuronal Signaling in HSV Latency
Principal Investigator: Roderic L. Smith, MD, PhD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke
Amount: $406,306
Term: July 1994-June 1999

Developmental Epilepsy and Conditional GABAa Function
Principal Investigator: Roderic L. Smith, MD, PhD
Source: National Institutes of Health
Amount: $295,880
Term: 2000-2004

Development of Positive Feedback during Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke - 3 R01 NS 34360
Amount: $403,297
Term: 1996-2005

Neuronal Ionic Homeostasis and Synaptic Inhibition
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke
Amount: $650,000
Term: 1996-2000

Presypnaptic Mechanisms of Epileptogenesis
Principal Investigator: Kevin J. Staley, MD
Source: Epilepsy Foundation of America, Postdoctoral Research Fellowship for Audrey Yee, MD
Amount: $160,000
Term: 1998-2000

Fellowship Training
Principal Investigator: Kevin J. Staley, MD
Source: Epilepsy Foundation
Amount: $40,000
Term: 2000-2001

Gating and Regulation of the Neuronal C1C-2 Chloride Channel
Principal Investigator: Kevin J. Staley, MD
Source: Human Science Frontier Program Organization for Jaideep Bains
Amount: $106,200
Term: 1998-2000

Ionic Basis of GABA-Mediated Neuronal Excitation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke
Amount: $350,000
Term: 1995-2000

Linking Synaptic Properties to Neuronal Network Operation
Principal Investigator: Kevin J. Staley, MD
Source: National Institutes of Health, National Institute of Neurological Disorders and Stroke
Amount: $345,653
Term: 1995-2004


 
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