PARTICIPATING FACULTY:

image of students in classroom Executive Committee: Paula L. Hoffman (Principal Investigator), Dept. of Pharmacology, University of Colorado Denver Health Sciences Center; Michael D. Browning, Dept. of Pharmacology, University of Colorado Denver Health Sciences Center; John K. Hewitt, Institute for Behavioral Genetics, University of Colorado at Boulder; and Nancy R. Zahniser, Dept. of Pharmacology, University of Colorado Denver Health Sciences Center.

Preceptors

Name and Email Address	Research Interest
Training Directors (Executive Committee)
Paula Hoffman, PhD Principal Investigator	neuropharmacology; neuroadaptation; alcohol tolerance and dependence; glutamate receptors; signal transduction; biochemical/genetic markers of alcohol abuse/dependence
Nancy Zahniser, PhD Co-Investigator	neuropharmacology; drug and alcohol abuse; dopamine transporter; cocaine sensitization; ethanol and NMDA receptors; neurotransmitter release
John Hewitt, PhD Co-Investigator	behavior genetics; twins; family studies; adolescence; substance abuse; development; quantitative trait loci
Training Preceptors
Thomas Beresford, MD	alcoholism; liver transplantation; brain imaging and alcohol; HPA axis and alcohol; treatment adherence; fatty acid ethyl esters and alcohol; cocaine abuse treatment; central pontine myelinolysis treatment; hepatitis C and alcohol
Thomas Crowley, MD	substance dependence; human genetics; functional magnetic resonance imaging; adolescent; conduct disorder; antisocial personality disorder; child abuse and neglect; risk-taking; impulsivity
Mark Dell'Acqua, PhD	signal transduction; phosphorylation; protein kinases; protein phosphatases; cAMP; calcium signaling; scaffold proteins in assembly of localized signaling complexes; glutamatergic synapses; postsynaptic density; NMDA and AMPA receptor localization and trafficking
Marissa Ehringer, PhD	molecular genetics, genomics, and bioinformatics; behavior genetics; alcohol, tobacco, and substance abuse
Robert Freedman, MD
Kim Heidenreich, PhD	neurodegeneration, apoptosis, autophagy, neurotrophic factors, signal transduction, insulin-like growth factors, dopamine neurons, cerebellar neurons
Christian Hopfer, MD	behavior genetics; adolescent substance abuse
Lawrence Hunter, PhD	bioinformatics; computational biology; computational pharmacology; natural language processing; gene expression arrays; knowledge-based systems
Kent Hutchison, PhD	gene, pharmacogenomics, craving, substance abuse, fmri, addiction
Thomas Johnson, PhD	genetics; QTLs; anesthesia; mice; gene mapping; bioinformatics; microarrays; congenics
David Jones, PhD	alcohol; protein structure; protein-alcohol complexes; NMR spectroscopy; x-ray crystallography
Sherry Leonard, PhD	nicotine; nicotinic receptor; schizophrenia; mental illness; nicotine addiction; molecular neurobiology; microarray
Dennis Petersen, PhD	molecular mechanisms of ethanol-induced liver injury; lipid peroxidation; proteomics
Richard Radcliffe, PhD	behavioral genetics; alcoholism; microarrays; mouse; alcohol tolerance; zebrafish; mutagenesis
Paula Riggs, MD	comorbid disorders; adolescents; substance use disorders; integrated treatment of comorbid psychiatric disorders and substance use disorders
James Sikela, PhD	genomics; disease gene identification; human gene; genome evolution
Andrew Smolen, PhD	human behavioral genetics; drug abuse; alcohol abuse; attention deficit hyperactivity disorder; candidate genes; DNA polymorphisms
Michael Stallings, PhD	substance use disorders; developmental psychopathology; quantitative genetics; QTL mapping; family studies
Boris Tabakoff, PhD	neuroscience; molecular biology; intracellular signalling; alcohol abuse; tolerance; humans/animals/cells; dependence; drug abuse; transgenics; genetics
Vasilis Vasiliou, PhD	ethanol/acetaldehyde metabolism; aldehyde dehydrogenases; oxidative stress; pharmacogenetics
Jeanne Wehner, PhD	genetics; ethanol/nicotine interactions; learning and memory
Christine Wu, PhD	quantitative proteomics, mass spectrometry, membrane protein topology, Chlamydia trachomatis
W. Michael Zawada, PhD	alcohol; apoptosis; brain repair; differentiation; dopamine; neurodegeneration; neuroprotection; neurotransplantation; Parkinson's disease; stem cells