Tabakoff, Boris Molecular pharmacology; pharmacogenetics; neuroadaptation and neurotransmitter metabolism/enzymology; CNS receptor molecular pharmacology and genetics/genomics of addiction
Bayer, K. Ulrich Molecular memory mechanisms in cellular signal transduction and neuronal function; CaMKII and Ca2+ signaling
Benke, Timothy A. Mechanisms of synaptic plasticity and impacts of development and epilepsy
Browning, Michael D. Molecular mechanisms of neuronal function with particular emphasis on protein phosphorylation
Churchill, Mair E. A. Structure and mechanism in gene regulation; biophysical and structural studies of protein-nucleic acid and protein-protein complexes in chromatin and bacterial pathogenesis
Dell’Acqua, Mark L. Organization of signaling complexes by protein kinase and phosphatase anchoring proteins; mechanisms regulating neuronal second messenger signaling in synaptic plasticity
Eisenmesser, Elan Viral protein/host protein interactions, enzyme dynamics, and ligand/receptor interactions involved in cancer progression
Fennessey, Paul V. Solutions to clinical problems using stable isotopes and mass spectrometry
Freed, Curt R. The dynamic role of dopamine in movement; neural transplantation for Parkinson’s disease
Freedman, Robert M. D. Central nervous system physiology and pharmacology and its application to clinical psychiatry
Heasley, Lynn E. Investigating the role of MAP kinases and specific receptor tyrosine kinases in normal and transformed growth of lung epithelial cells using techniques of molecular and cell biology in lung epithelial cells and human lung cancer cell lines
Heidenreich, Kim A. Signal transduction pathways that regulate neuronal survival and apoptosis
Henson, Peter M. Inflammatory process as a paradigm of complex interacting cell networks and communication molecules and as a component of human diseases
Hodges, Robert S. Structure-function studies of multi-protein complexes; de novo design of model proteins to test our understanding of protein folding and structure and to design proteins with the desired biological/immunological activities; synthetic peptide vaccines and antimicrobial therapeutics
Hoffman, Paula L. Neuropharmacology; mechanisms of alcohol tolerance, dependence, and craving; genetic aspects of alcohol dependence and affective disorders; biochemical/molecular biological/genetic analysis of CNS receptors and signal transduction systems
Hunter, Lawrence Computational biology, bioinformatics, gene expression array analysis, natural language processing, biomedical ontologies, machine learning
Jones, David N. M. Molecular mechanism of alcohols and anesthetic actions; structure and function of biomolecules; NMR spectroscopy, x-ray crystallography, biophysics and molecular biology
Kappler, John W. The study of the interaction between the T cell receptor and its signal ligands
Krushel, Leslie A. Mechanisms and regulation of protein synthesis in the nervous system with a focus on the understanding of translation in learning and memory and disease states
Kutateladze, Tatiana G. Biochemistry and structural biology, NMR and crystal structures of proteins implicated in cancer, structure based drug design
Leonard, Sherry S. Molecular neurobiology of nicotine addiction in mental illness
Leslie, Christina C. Signal transduction mechanisms regulating phospholipase A2 activation and the production of lipid mediators of inflammation
Li, Chuan-Yuan Molecular mechanisms of tumor response to therapy; roles of stem cells in tumor response to therapy
Malkinson, Alvin M. Genetics of susceptibility to lung tumors in mice; mechanisms of lung tumor promotion; signal transduction
Maller, James L. Biochemistry of cell division and early development; cell cycle control; protein phosphorylation and oncogene action
Murphy, Robert C. Pharmacology and biochemistry of leukotrienes and bioactive lipids, lipid mediators of cellular response using biochemical mass spectrometry
Nemenoff, Raphael A. Signaling pathways controlling growth and differentiation of vascular smooth muscle cells; Role of eicosanoids in lung cancer
Petersen, Dennis R. Molecular mechanisms of chemical and drug toxicity
Port, J. David G-protein linked receptors and their regulation; regulation of mRNA stability
Sather, William A. Structural basis of calcium channel function, including selective ion permeability and neuromodulation of channel gating
Schiemann, William P. Mechanisms of TGF-β-mediated tumor suppression and tumor promotion; cloning and characterization of TFG-β-regulated signaling molecules and secretory proteins; expression proteomics and genomics, biochemistry, and cell biology
Serkova, Natalie J. Magnetic Resonance Spectroscopy (MRS) based metabonomics; Magnetic Resonance Imaging (MRI); immunosuppressive drug toxicodynamics and toxicokinetics; ischemia/reperfusion in transplantation; MRI/MRS in oncology
Sikela, James M. Neurogenomics; disease gene discovery; human genome evolution and variation
Sorkin, Alexander D. Endocytosis, intracellular trafficking and signaling of growth factor receptors, dopamine transporter, dopaminergic neurons
Thorburn, Andrew M. Understanding the signaling mechanisms that control apoptosis in cancer development and during the response of tumor cells to cancer therapeutics
Traystman, Richard J. Neuroscience, cerebrovascular physiology, stroke, cardiac arrest/CPR, respiration, cardiopulmonary physiology
Wu, Christine C. Proteomic analysis of membrane proteins from complex biological samples using mass spectrometry; molecular mechanisms of intracellular trafficking and organellar biogenesis
Zahniser, Nancy R. Regulation of dopamine transporters; mechanisms underlying cocaine’s actions; neurotransmitter receptors and release in brain
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