Celia Sladek

Curriculum vitae

Celia D. Sladek, Ph.D.

Professor
Department of Physiology and Biophysics
UCD at Fitzsimons

RC-1 North Tower, P18-7127. PO Box 6511, Mail Stop F8307. Tel (303) 724-4526. Fax (303) 724-4501.
Email celia.sladek@UCHSC.edu

CONTENTS

| Education | Academic Appointments | Honors | Service | Research Funding | Trainees
| Invited Presentations | Symposia and Meetings Organized | Publications | Selected Reviews |

EDUCATION:
B.A.: Hastings College, Hastings, Nebraska (Biology),1966
Cum Laude with high distinction in Biology
M.S.: Northwestern University Medical School (Physiology), 1969
Ph.D.: Northwestern University Medical School (Physiology), 1970

CONTENTS

ACADEMIC APPOINTMENTS:
Professor of Physiology, University of Colorado Health Science Center, 2002-present
Chair, Department of Physiology and Biophysics, The Chicago Medical School, 2001 - 2002
Acting Chair, Department of Physiology and Biophysics, The Chicago Medical School, 2000 - 2001
Vice Chair, Department of Physiology and Biophysics, The Chicago Medical School, 1993 - 2000
Professor of Physiology and Biophysics and Neurology, The Chicago Medical School, North Chicago, Illinois, 1991 - 2002.
Professor of Neurology, and Neurobiology and Anatomy, University of Rochester School of Medicine & Dentistry, Rochester, New York. 1988 - 1991.
Associate Professor of Neurology, and Neurobiology and Anatomy, University of Rochester School of Medicine & Dentistry, Rochester, New York. (with unlimited tenure, l983), 1980 - 1988
Assistant Professor of Neurology and Anatomy, University of Rochester School of Medicine & Dentistry, Rochester, New York, 1976 - 1980.
Research Associate, Department of Neurology, and Neurobiology and Anatomy, University of Rochester School of Medicine & Dentistry, Rochester, New York. 1974 - 1976
Assistant Professor of Biological Sciences, State University of New York, Brockport, New York, 1973 - 1974
Assistant Professor of Physiology, University of Illinois, College of Medicine,Chicago,IL, 1970 - 1973.

CONTENTS

HONORARY:
Alpha Chi
Buswell Fellow, University of Rochester, 1976-1977
Research Career Development Award, 1977-1982
Morris Parker Award for Excellence in Research - Chicago Medical School, 1994
Elected to Alpha Omega Alpha, Honor Medical Society, 2001
Erlanger Distinguished Lecturer, American Physiology Society, 2002

CONTENTS

SERVICE:
Research review committees:
Program project site visitor, National Heart Lung Institute
Special study section, National Institute of Arthritis and Metabolic Diseases
Ad hoc member of Neurological Sciences Study Section, NIH, October, 1986
American Heart Association, Cardiovascular A Research Study Committee, 1986-1990
International Human Frontier Science Program Organization
Ad Hoc Program Project Review Committee for National Institute of Aging, 1992.
Ad Hoc Program Project Review Committee for National Heart Lung Institute, 1993.
American Heart Association of Metropolitan Chicago Grant in Aid Review Committee, January, 1994.
Ad hoc member of Experimental Cardiovascular Sciences Study Section, NIH, October, 1994.
American Heart Association of Metropolitan Chicago Grant in Aid Review Committee, January, 1995.
Ad Hoc member Neurological Sciences 2 Study Section, NIH, March and October 1996.
Member of Neuroendocrinology Panel, NSF, April, 1996.
Member, American Heart Association, Cardiovascular Regulation Study Section, 1996-1999.
Member Neurological Sciences 2 Study Section, NIH, 1997-1998.
Member Integrated, Functional, and Cognitive Neuroscience - 2 Study Section, NIH, 1998-2001.
Member, NIH Special Emphasis Grant Review Panel - November, 1999.
Member, NIH Special Emphasis Grant Review Panel for Centers in Biomedical Research Excellence, June 2000.

Editorial Board Memberships:
Brain Research Bulletin - Editor, 1980-89
Peptides - Editorial Advisory Board, 1980-1985
Experimental Neurology - Editorial Advisory Board, l988-present
Section Editor - Neuroendocrine and Homeostatic Mechanisms, 2001-
Neurobiology of Aging - Editorial Advisory Board, 1990-1994
American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology - Editorial Board, 1994-1999

National Organizations:
Member of Anatomy-Physiology Committee of the College Proficiency Examination Program of the University of New York, 1973-1976.
Member of the Steering Committee for the Central Nervous System Section of The American Physiological Society, 1991-1997.
Secretary-Treasurer of the Steering Committee for the Central Nervous System Section of The American Physiological Society, 1992-1994
Member of Program Advisory Committee, American Physiological Society, 1992-1994.
Chair, Steering Committee for the Central Nervous System Section of The American Physiological Society, 1994-1996
Member of Section Advisory Committee, American Physiological Society, 1994-1996.
Member of Nominating Committee for American Physiological Society, 1994-1995.
Member of Women in Physiology Committee, American Physiological Society, 1995-1996.
Chair, Women in Physiology Committee, American Physiologcial Society, 1995-1996.
FASEB Excellence in Science Award Committee, 1995-1996.
Member, Committee on Committees, American Physiology Society, 1996-1998., Chair, 1999-2000.
Councillor, American Physiology Society, 1996-1999.
Chair of Section Advisory Committee and member of Council, American Physiology Society, 2000-2002.

Home Institution:
Member of Advisory and Admissions Committee for Medical Scientist Training Program (M.D.-Ph.D. program) , University of Rochester, 1984-1989
President of Rochester Chapter of Society for Neuroscience, 1989-1990
Director, Interdepartmental Neuroscience Graduate Program, University of Rochester, 1989-1991.
Senator, Faculty Senate, FUHS/Chicago Medical School, 1993-1995
Director, Graduate Program in Physiology, Chicago Medical School, 1993-1994.
Chair, Faculty Appointments, Promotions, and Tenure Committee, Chicago Medical School, 1997-2000.

CONTENTS

RESEARCH FUNDING:

Current Funding:
NIH: RO1 - NS27975 Principal investigator, Regulation of Vasopressin mRNA, 40% effort, 4/1/91 - 6/30/03, direct costs for '01-'02 $154,616.
NIH: R01-NS44835-01 Principal investigator, Neuropeptide Regulation of Vasopressin/Oxytocin Secretion. 30% effort, 3/02-2/07, direct costs for '02-'03, $190,000.

Previous Funding:
NIH:
RO1 - AG12701, Principal Investigator, 25% effort. Regulation of vasopressin mRNA during aging. 12/1/94 - 11/30/98. $299,271 total direct costs.
Minority Research Supplement to RO1 - AG12701. 8/95-11/97, Provided support for Judith Catudioc-Vallero (Ph.D./M.D. student) to perform Ph.D. research. $47,000 total direct costs.
Minority Research Supplement to RO1 - NS27975. 2/93-6/94, Provided support for Kirsten Fisher (medical student) to perform research in my laboratory.
PO1 - NS24032, Co-investigator, 10% effort (John R. Sladek's subcomponent of program project grant to Eugene Redmond, Yale University, Neural Grafts in a Primate Model of Parkinson's Disease. 7/1/89-6/30/00, yearly direct costs for my subcomponent, $10,000.
RO1-AM19761. Neurological Mechanisms Controlling Vasopressin Secretion, principal investigator; 40% effort; Continuous funding from 5/1/77 - 4/30/91; total direct cost 5/1/87 - 4/30/91, $261,081.
R35 - AG09016. Principal investigator on subcomponent of LEAD award to Paul Coleman, 10% effort, Gene regulation in vasopressin neurons during aging, 4/1/90 - 3/31/92, total direct costs $84,000.
RO1 - HL28172, Regulation of Vasopressin in Hypertension, principal investigator, 30% effort; continuous funding from 1/1/82 - 12/31/89; total direct cost 1/1/85 - 12/31/89, $245,231.
K04 - NS00259, Research Career Development Award, 7/77-6/82, total direct cost, $135,000.
R29 - NS24661, Co-investigator, 5% effort (Dave Earnest, principal investigator). Neural Control of Suprachiasmatic Function 4/1/87 - 3/31/92, $340,000.
RO1 - DA07080, Co-investigator, 5% effort (Carol Kellogg, principal investigator) Drug-stress interactions in pregnancy and development. 8/1/90-7/31/93, annual direct costs $102,694
RO1 - NS15109, Co-investigator, 5% effort (Don Gash, principal investigator) Neural Transplants: Growth, Reinnervation in the Brain 3/1/79 - 2/92 (Javitz Award), total direct costs, $797,000.
R21 - AG01456, Co-investigator (Robert J. Joynt, principal investigator) Aging and the Magnocellular Neurosecretory System 5/1/79 - 4/30/82, $180,000.
RO1 - NS15816, Co-investigator, 5% effort, (John R. Sladek, Jr., principal investigator) Neuronal Interactions: Vasopressin-Norepinephrine, 7/1/81 - 6/30/88; total direct costs, 7/1/84 - 6/30/88, $306,000.
PO1 - AG03644, Co-investigator, 5% effort, (Robert Joynt, prinicpal investigator) Clinicopathologic Correlates of Alzheimer's Disease, 4/1/84 - 3/87.
RO1 - HL22728. Co-investigator, 5% effort, (Martha Blair, principal investigator) Neural Control of Renin Secretion, 7/84 - 6/88; total direct costs, $256,311.
RO1 - HD18418,Co-investigator, 10% effort, (Gloria Hoffman, principal investigator) LHRH: pituitary and non-pituitary actions, 12/84 - 8/88, $236,100.

VA Merit Award (Collaborator), P.I.: Janet Amico, M.D., University of Pittsburgh Sch. Med. "Oxytocin Gene Expression and Secretion" 4/1/96-3/31/99.

NSF: BNS-79-24767, Co-principal investigator (Robert J. Joynt, principal investigator) Neurochemistry Multiuser Laboratory 2/80-1/81, $70,000.

CONTENTS

TRAINEES:

Medical Student Research Fellows:
Patrice Langston, 1992
Marie Brister, 1992
Karen K. L. Gin, 1993
Sandeep Chaudhary, 1994
Ben Cohen, 1995-1997 (rec'd John J. Sheinin Research Award)
Shenon Badre, 1996-1998
Khanh Nguyen, 1998, 1999, (rec'd award for summer research poster)
Syed A. Mehmood, 1999
Angeline Roman, 2000
Yigit Guner, 2000
Prabhjot Uppal, 2001
Eleanora Maries, 2001

Graduate Students:
Henry Khachaturian, Ph.D., 1979, currently Director of Extramural Studies, NIMH
Robert Elfont, M.D.-Ph.D., 1990, University of Rochester
Rita Gosh; Ph.D., 1994, Chicago Medical School. Awards: Best Poster Presentation Minisymposium on Reproductive Biology, Northwestern Univeristy, 1992; Graduate Student Award, Chicago Chapter of Soc. Neuroscience, 1993. Current position: Resident in Ob-Gyne, Southern Illinois Univ. Springfield, IL
Kerry Swenson; M.D./Ph.D.,1996, Dept. of Physiology and Biophysics, Chicago Medical School. Awards: Best Student presentation, Midwest Physiology Society Meeting, 1996; Dean's Award from Chicago Medical School. Current position: Resident in OB/Gyne at John Hopkins Hospital
Judith Catudiac-Vallero, M.D./Ph.D., 1997 Chicago Medical School. Current position: Pediatric Resident, Univ. Calif. at Davis
Zhilin Song, Ph.D., 1999, Chicago Medical School. Awards: Best Student presentation, Midwest Physiology Society. Current position: Postdoctoral Fellow, Dept. Neuroscience, UCRiverside.
Del Morsette, M.D./Ph.D., 1999, Chicago Medical School. Awards: Ben Blivass Travel Award. Current position: Resident, Neurosurgery, Univ. Texas San Antonio
John Kapoor, M.D./Ph.D., 2000, Chicago Medical School. Awards: Runner-up, Sigma Xi Graduate Student Poster Competition, Chicago Medical School, 1999. American Physiology Society Proctor and Gamble Professional Opportunity Award, 1999, 2000, and 2001.Sigma Xi Grant-in-Aid award, 1999. Current position: Resident, Neurosurgery, University of Chicago.

Postdoctoral fellows:
William E. Armstrong, Ph.D., 1979-80, Supported by NIH postdoctoral fellowship NS-06290. Current position: Professor of Anatomy and Neurobiology, Univ Tenn Sch Med
Paul Aravich, Ph.D., 1982-84. Supported by NIMH postdoctoral fellowship MH08872. Current position: Assoc. Prof. Anatomy and Neurobiol., East Virginia Med Sch.
Barbara Davis, Ph.D., 1982-84. Supported by NIMH postdoctoral fellowship MH08811. Current position: Assoc Dean Students, NY Chiropractic College
Richard Clough, Ph.D., 1983-87. Supported by NIMH postdoctoral fellowship MH09136. Current position: Prof. of Anatomy, Southern Illinois Univ Sch. Med.
David Earnest, Ph.D., 1984-87. Supported by NIMH postdoctoral fellowship MH09129. Current position: Assoc Prof Human Anatomy and Medical Neurobiology, Texas A & M Univ College Med, College Station, Texas
Chana Yagil, DMD, M.S., 1987-88. Supported by Kidney Foundation of Upstate New York, Am Heart Assoc. Grant-In-Aid, N.Y. Affiliate. Current position: Member, Lab Mol Med, Barzilai Med Ctr, Ashkelon, Israel
Joanne Mathiasen, Ph.D., 1992-96. Supported by NINDS postdoctoral fellowship NS09721 from 1994-96. Current position: Senior staff scientist, Cephalon
Suwit (Jack) Somponpun, Ph.D., 2000-present Supported by AHA Midwest Affiliate postdoctoral fellowship, 2001-2003

Undergraduate students:
Roger Kapoor, summer research fellow 1999, 2000, 2001. Supported by a Summer Research Fellowship from the EndocrineSociety, 2000. Supported by a Summer Research Fellowship from the Am. Physiol. Soc, 2001.

CONTENTS

INVITED PRESENTATIONS:

U.S. - Japan Joint Seminar on Vasopressin. Nikko, Japan; Sept. 1979. U.S. Organizers: Leonard Share and William Sawyer.

Michigan Chapter Meeting of the Society for Neuroscience, East Lansing Michigan, 1979.

Neuroscience Society Workshop on the Brain and the Renin-Angiotensin System. Organized by William Ganong. November, 1979.

Seminar: Department of Biology, Erindale College, Toronto, Canada. "Neural Regulation of Vasopressin Release," March, 1980.

Conference on the Radioimmunoassay of Vasopressin, Marina del Rey, California, April, 1980.

Brain-Endocrine Interaction Symposium IV: "Neuropeptides: Development and Aging." Rochester, New York, September, 1980.

Seminar: Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee. "Regulation of Vasopressin Release: Osmotic and Neurochemical Mechanisms," 1981.

International Conference on the Brattleboro Rat. "The Brattleboro Heterozygote Rat as a Model for Neurohypophyseal Aging: Response to Dehydration." Hanover, New Hampshire, September, 1981.

International Neuroendocrine Symposium. "Effect of Aging on Regulation of Vasopressin Release." Maebishi, Japan, October, 1981.

Fifth International Taniguchi Symposium on Peptidergic and Aminergic Neurons. "Noradrenergic Control of Vasopressin Release." Kyoto, Japan, October, 1981.Gordon Conference on "Cardiovascular Role of Brain Angiotensin and Other Peptide Hormones." Ventura, California, February 8-12, 1982. Presentation: "In vitro Studies on the Control of Vasopressin Release."

Third International Conference on the Neurohypophysis, Babraham, England, September 14-16, 1982. Invited lecture: Interaction of neurotransmitters, neuropeptides and the osmotic pressure in the control of vasopressin release.

Seminar: "Department of Physiology, Dartmouth Medical School. "Noradrenergic Regulation of Vasopressin Release," October, 1982.

Winter Conference on Brain Research, Keystone, Colorado, January 22-29, 1983. Invited participant in Workshop entitled "In vitro and in vivo culture of transmitter identified neurons: experimental models and their utilization."

Seminar: Department of Physiology, University of Texas Health Science Center at Dallas. "Regulation of Vasopressin Release by Neurotransmitters, Neuropeptides, and Osmolality," March, 1983.

Seminar: Cardiovascular Research Seminar, Cleveland Clinic. "Control of Vasopressin Release in Normotensive and Hypertensive Rats: Role of Angiotensin II," September, 1983.

Seminar: Neuroscience Society, Queens University Medical School, Kingston, Ontario. "Characteristics of Hypothalamic and Brainstem Catecholamine Neurons in Culture," May, 1984.

Aspen Conference on Vasopressin, Aspen, Colorado, August, 1984. Invited presentation: "Role of afferent projections to the supraoptic nucleus in the osmotic regulation of vasopressin release."

Winter Conference on Brain Research, Vail, Colorado, 1985. "Regulation of vasopressin release in spontaneously hypertensive rats."

Endocrine-Metabolism Seminar Series, University of Rochester: "Vasopressin release in normotensive and hypertensive rats." May 14, 1985.

Seminar: Department of Biology, Pennsylvania State University, March, 1986.

Seminar: Department of Physiology, University of Texas Health Science Center, Dallas, Texas. "Regulation of Oxytocin Release from Hypothalamo-neurohypophyseal Explants," September, 1986.

Seminar: University Lecture Series, University of Texas Health Science Center at Dallas. "Vasopressin in Hypertension," September, 1986.

Seminar: Department of Pharmacology, University of Texas Health Science Center at San Antonio. "Control of Vasopressin Release by Neurotransmitters and Osmotic Stimuli," September, 1986.

NIH Conference on Mechanisms of Physical and Emotional Stress. Bethesda, Maryland, November, 1986. "Regulation of Vasopressin Secretion in Vitro."

Seminar: Neuroscience Seminar Program. Bowman Gray School of Medicine. "Neural Control of Vasopressin and Oxytocin Release," December, 1986.

Seminar: Neuroscience Program. Northwestern University. "In Vitro Approaches to Studying the Hypothalamus," April, 1987.

Seminar: Physiology Department, State University of New York at Buffalo. "Regulation of Vasopressin and Oxytocin Release by Neurotransmitters and Osmotic Stimulation; May, l987.

Second International Vasopressin Conference. Smugglers Notch, Vermont, August, l987. "Comparison of vasopressin and oxytocin release in response to osmotic and cholinergic stimulation."

Seminar: Physiology Department, West Virginia University Medical School, Morgantown, WV, "Vasopressin in Hypertension", September, 1987.

Guest Lecturer: Physiology Department West Virginia University Medical School, Morgantown, WV, "Control of Vasopressin Release by Neurotransmitters and Osmotic Stimuli," September, 1987.

Seminar: Neurobiology and Behavior Series, University of Illinois, Urbana, Ill. "Regulation of vasopressin and oxytocin release by neurotransmitters and osmotic stimuli," December, 1987.

Antidiuretic Hormone: Satellite Conference to the International Endocrine Meeting, Hakone, Japan. July, l988. "The vasopressin response to osmotic stimulation is rate sensitive."

Neuroscience Symposium sponsored by the Local Chapter of the Society for Neuroscience, Emory University, Atlanta, Georgia, June, 1988.

Seminar: Nephrology Unit of the Department of Medicine, University of Rochester, Rochester, NY. "Regulation of Vasopressin Release by Neurotransmitters and Osmotic Stimuli." January, l989.

Seminar: Neuroscience Program, Michigan State University, East Lansing, Michigan. "Control of Vasopressin Releaseby Neurotransmitters and Osmotic Stimuli," March, l989.

Seminar: Mental Health Research Institute, University of Michigan, Ann Arbor, Michigan. "Control of Vasopressin Release by Neurotransmitters and Osmotic Stimuli," March, l989.

Third International Vasopressin Conference, Montpellier, France, August, 1990. Effects of vasopressin analogues in hypertension.

Seminar: Department of Physiology and Biophysics, University of Health Sciences/The Chicago Medical School, North Chicago, IL. "Regulation of Vasopressin Gene Expression," April, 1991.

Seminar: Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin. "Regulation of Vasopressin Gene Expression," October 1991.

Neuroendocrine/Neuropeptide Workshop, Fall meeting of Chicago Chapter of Society for Neuroscience, Chicago, IL, "Regulation of Vasopressin Gene Expression," December, 1991.

Seminar: Department of Physiology, University of Illinois School of Medicine, Chicago, Illinois. "Regulation of Vasopressin Gene Expression," February 1992.
Seminar: Neuroscience Seminar Series, Loyola Universtiy School of Medicine, Maywood, Illinois. "Regulation of Vasopressin Gene Expression," March 1992.

Satellite Symposium of the N.I.C.E. 1992: Neurohypophysial Peptide Systems, Spa-Liege, Belgium, September, 1992.

Symposium: Society for Neuroscience. Anaheim, Calif, Symposium: Regulation of Neuronal Peptide Gene Expression: Lessons from the Neurohypophyseal System, October, 1992.

Seminar: Department of Biological Science, Northwestern University, Evanston, IL. "Regulation of Vasopressin Gene Expression," November, 1992.

Seminar: Department of Molecular Biology and Pharmacology, Chicago Medical School, North Chicago, IL, "Regulation of Vasopressin Gene Expression," January 13, 1993.

Seminar: Department of Microbiology and Immunology, Chicago Medical School, North Chicago, IL. "Regulation of Vasopressin Gene Expression," April 6, 1993.

Seminar: Neuroscience Program, Iowa State University, Ames, Iowa, "Regulation of Vasopressin Gene Expression," April 30, 1993.

Seminar: Physiology Department, Dartmouth Medical School, Hanover, New Hampshire, "Regulation of Vasopressin Gene Expression," May 20, 1993.

Presentation in Poster Discussion Session at IV. International Vasopressin Conference, Berlin, Germany, May 1993. "Dehydration fails to increase vasopressin mRNA in the supraoptic nucleus of aged rats."

Symposium: "Mapping Neuroendocrine Regulatory Systems" at the Canadian Federation of Biological Societies meeting, June 1993.

1993 FASEB Summer Research Conference on Circumventricular Organs, Saxtons River, Vermont, July 17-22, 1993.

Seminar: Department of Physiology and Biophysics, Chicago Medical School, North Chicago, IL, "Quantitation of Vasopressin mRNA: Effect of Aging, Osmotic stimulation, and Neurotransmitters." October, 1993.

1994 Northwestern Symposium on Women in Science. "Women and Men in Science: Are we approaching equality?" October 31, 1994.

Seminar: Department of Physiology and Biophysics, Chicago Medical School, North Chicago, IL. "Mechanism of Osmotic Regulation of Vasopressin mRNA." November 10, 1994.

Symposium: Sladek, C.D. Neurochemical control of peptide synthesis and secretion using a hypothalamic tissue culture model. Winter Neuropeptides Conference, January 1995.

Seminar: Neuroscience Program, University of Tennessee, Memphis, "Osmotic Regulation of Vasopressin mRNA: Effect of Aging and Neurotransmitters" November 7, 1995.

Seminar: Department of Pharmacology, University of Iowa, Iowa City, "Osmotic Regulation of Vasopressin mRNA: Effect of Aging and Neurotransmitters" November 1, 1995.

Seminar: Department of Neuroscience, Chicago Medical School, "Osmotic Regulation of Vasopressin mRNA: Effect of Aging and Neurotransmitters" December 5, 1995.

European Winter Conference Brain Research. "Role of excitatory amino acids in osmotic regulation of vasopressin release and mRNA. Serre Chevalier, France, March 16-23, 1996.

European Winter Neuropeptide Conference. "Regulation of Vasopressin Release by Glutamate: Role of NMDA and non-NMDA Receptors in Osmotically Stimulated Release, Kitzbuhel, Austria, February, 1997.

Seminar: Department of Biological Sciences, DePaul University, "Osmotic Regulation of Vasopressin Release: Effect of Aging and Neurotransmitters. February 20, 1997.

Seminar: Department of Pharmacology, University of Texas, San Antonio, "Osmotic Regulation of Vasopressin mRNA: Interaction of steroid hormones and neurotransmitters." April 23, 1997.

Seminar: Pierce Laboratory, Yale University, "Osmotic Regulation of Vasopressin Secretion: Effect of Aging and Steroid Hormones". October 6, 1997.

Seminar: Department of Physiology, University of Kansas, Kansas City, Kansas. "Osmotic Regulation of Vasopressin Release and mRNA: Effect of Neurotransmitters and Steroid Hormones". March, 1998.

Seminar: Department of Physiology, West Virginia University, Morgantown, West Virginia. "Osmotic Regulation of Vasopressin Release and mRNA: Glutamate and Gonadal Steroid Interactions." June, 1998.

Seminar: Department of Physiology, Robert Wood Johnson Medical School, Piscataway, NJ. "Osmotic Regulation of Vasopressin Release and mRNA: Glutamate and Gonadal Steroid Interactions." January, 1999.

Seminar: Department of Physiology, University of Illinois, Champaign/Urbana, IL. "Osmotic Regulation of Vasopressin Release and mRNA: Glutamate and Gonadal Steroid Interactions." February, 1999.

European Winter Neuropeptide Conference. "Gonadal steroids modify vasopressin secretion to osmotic stimulation" In session: "Salt, the brain, and cardiovascular regulation. La Plagne, France, March 6-13, 1999.

Seminar: Department of Physiology, University of Nebraska, Omaha, Nebraska."Osmotic Regulation of Vasopressin Release and mRNA: Glutamate and Gonadal Steroid Interactions." May, 1999.

Neuroendocrine Perspectives Symposium: Department of Neuroscience, Chicago Medical School. "Effect of Steroid hormones on Neurohypophysial Hormone Secretion. August 10, 1999.

World Congress on Neurohypophyseal Hormones. Plenary Speaker: "Osmotic Regulation of Vasopressin Release and mRNA: Glutamate and Gonadal Steroid Interactions". Edinburgh, Scotland. August 28-September 2, 1999.

Seminar: Department of Physiology, Southern Illinois University, Carbondale, IL. "Regulation of Vasopressin Release and mRNA: Autoregulation, Steroid Hormones, and Neurotransmitter Interactions. October 8, 1999.

Seminar: Department of Physiology, Queen's University, Kingston, Ontario. "Regulation of Vasopressin Release and mRNA: Osmoregulation, Steroid Hormones, and Neurotransmitter Interactions". March 27, 2000.

Seminar: Department of Physiology, University of Illinois, Rockford, "Regulation of Vasopressin Release and mRNA: Osmoregulation, Steroid Hormones, and Neurotransmitter Interactions." March 20, 2001.

Seminar: Department of Physiology, University of Florida, Gainesville. "Neurotransmitter and neuropeptide interactions in the regulation of vasopressin and oxytocin secretion." April 19, 2001.

Seminar: NINDS, NIH, "Neurotransmitter and neuropeptide interactions in the regulation of vasopressin and oxytocin secretion." June 13, 2001.

Seminar: University of Colorado, Department of Medicine, Denver, Colorado. "Neurotransmitter and neuropeptide interactions in the regulation of vasopressin and oxytocin secretion." June 25, 2001.

Seminar: University of Colorado School of Medicine, Department of Physiology, Denver, Colorado. "Neurotroansmitter, neuropeptide, and steroid hormone interactions in the regulation of vasopressin and oxytocin secretion." September 26, 2001.

Seminar: University of Wyoming, Department of Physiology, Laramie, Wyoming. "Regulation of the Neurohypophyseal System: Neurotransmitter, Neuropeptide, and Steroid Hormone Interactions", December 6, 2001.

Erlanger Distinguished Lecturer, Central Nervous System Section of the American Physiology Society. "Regulation of the Neurohypophyseal System: Neurotransmitter, Neuropeptide and Steroid Hormone Interactions." Experimental Biology '02, New Orleans, LA., April 20-24, 2002.

CONTENTS

SYMPOSIA AND MEETINGS ORGANIZED:

Aspen Conference on Vasopressin, Aspen, Colorado, August, 1984. Co-organizer for the session on Neural Control of Vasopressin Release.

Winter Conference on Brain Research, Vail, Colorado, January 27-February 1, 1985. Organized session on Hypothalamic Control of Cardiovascular Function.

Fall meeting of the Chicago Chapter of the Society for Neuroscience, December, 1991. Organized workshop entitled Regulatory Mechanisms in Neuroendocrine Systems.

Society for Neuroscience. Anaheim, Calif, October, 1992. Organized symposium: Regulation of Neuronal Peptide Gene Expression: Lessons from the Neurohypophyseal System.

1993 FASEB Summer Research Conference on Circumventricular Organs, Saxtons River, Vermont, July 17-22, 1993. Session title: "Pituitary Neural Lobe"

Fall meeting of Chicago Chapter of Society for Neuroscience. December 3, 1993.

Winter Conference on Brain Research, Snowmass, Colorado, January 23-30, 1999. Session title: Magnocellular Neurons: Bigger is Better!.
Annual meeting of the Midwest Physiological Societies, June 5th and 6th, 2000. Chicago Medical School.

Experimental Biology 2001. March 31-April 4, 2001, Orlando, Florida. Symposium co-organizer with J. Thomas Cunningham entitled Vasopressin: Integrative and Cellular Mechanisms of Release and Actions.

International Union Physiological Sciences 2001. August 26-31, 2001, Christchurch, New Zealand. Co-organizer of with Glenn Hatton of a Poster Focus Discussion Section entitled "Hypothalamic Involvement in Neuroendocrine, Circadian, and Autonomic Regulation".

CONTENTS

PUBLICATIONS:

Sladek, C.D. and J.F. Snarr. Effect of the exogenous amino acid concentration on the rate of gluconeogenesis in liver slices. Proc. Soc. Exp. Biol. Med. 138:181-185, 1971.

Sladek, C.D. and J.F. Snarr. Concentration dependent inhibition of hepatic gluconeogenesis by insulin. Proc. Soc. Exp. Biol. Med. 146:194-199, 1974.

Hakim, A.A., C.D. Sladek and S.R. Rosenthal. Thermal injury: Action of acute burn serum on rat heart papillary muscles. Proc. Soc. Exp. Biol. Med. 144:359-363, 1973.

Hakim, A.A., C.D. Sladek and R. Lucke. Thermal injury: Lympho-cyte mediated immunological reactions. Internat. Res. Commun., May, 1973.

Sladek, C. D. and A.A. Hakim. Thermal injury: Effect of a glyco-protein from scalded human skin on gluconeogenesis. Internat. Res. Commun., August, 1973.

Sladek, C.D. Gluconeogenesis and hepatic glycogen formation in relation to the rat estrous cycle. Horm. Metab. Res. 6:217-221, 1974.

Sladek, C.D. The effect of human chorionic somatomammotropin and estradiol on gluconeogenesis and hepatic glycogen formation in the rat. Horm. Metab. Res. 7:50-54, 1975.

Van Alstyne, E.L., C.D. Sladek and D.C. Smith. The effect of thermal injury on plasma carnitine in rats. Experentia 33:863, 1977.

Scott, D.E., J.R. Sladek, Jr., K.M. Knigge, G. Krobisch-Dudley, D.L. Kent and C.D. Sladek. Localization of dopamine in the endocrine hypothalamus of the rat. Cell Tiss. Res. 166:461-473, 1976.

Joynt, R.J., J.H. Feibel and C.D. Sladek. Elevated antidiuretic hormone levels after cerebrovascular accidents. Trans. Am. Neurol. Assoc. 101:164-166, 1976.

Sladek, C.D. and K.M. Knigge. Cholinergic stimulation of vasopressin release from the rat hypothalamo-neurohypophyseal system in organ culture. Endocrinology 101:411-420, 1977.

Sladek, C.D. and K.M. Knigge. Osmotic control of vasopressin release by organ cultured hypothalamo-neurohypophyseal explants from the rat. Endocrinology 101:1834-1838, 1977.

Sladek, J.R. and C.D. Sladek. Localization of serotonin within tanycytes of the rat median eminence. Cell and Tissue Research 186:465-474, 1978.

Sladek, C.D. and R.J. Joynt. Osmotic stimulation of vasopressin release: Inhibition by tetrodotoxin. Brain Research 151: 424-429, 1978.

Sladek, C.D. and R.J. Joynt. Angiotensin stimulation of vaso-pressin release from the rat hypothalamo-neurohypophyseal system in organ culture. Endocrinology 104:148-153, 1979.

Sladek, C.D. and R.J. Joynt. Characterization of cholinergic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system. Endocrinology 104:659-663, 1979.

Sladek, C.D. and R.J. Joynt. Cholinergic involvement in osmotic control of vasopressin release by the organ cultured rat hypothalamo-neurohypophyseal system. Endocrinology, 105:367-371, 1979.

Sladek, C.D. and R.J. Joynt. Role of angiotensin in the osmotic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system. Endocrinology 106:173-178, 1980.

Gash, D., C.D. Sladek and D.E. Scott. Cytodifferentiation of the supraoptic nucleus correlated with vasopressin synthesis in the rat. Brain Research 181:345-355, 1980.

Gash, D., J.R. Sladek, Jr. and C.D. Sladek. Functional development of grafted peptidergic neurons. Science 210:1367-1369, 1980.

Sladek, C.D., D.M. Gash, H. Khachaturian, D.E. Scott and J.R. Sladek, Jr. Maturation of the supraoptic nucleus: A multidisciplinary analysis. Peptides 1: Suppl 1:51-67, 1980.

Gash, D., C. Sladek and J.R. Sladek, Jr. Functional capability of normal fetal hypothalamic implants in the third ventricle of adult Brattleboro rats. Peptides 1: Suppl 1:125-134, 1980.

Joynt, R.J., J.H. Feibel and C.D. Sladek. Antidiuretic hormone levels in stroke patients. Ann. Neurology 9:182-184, 1981.

Sladek, C.D., T.H. McNeill, C.M. Gregg, M.L. Blair and R.B. Baggs. Vasopressin and renin response to dehydration in aged rats. Neurobiology of Aging 2:293-302, 1981.

Armstrong, W.E., C.D. Sladek and J.R. Sladek, Jr. Noradrenergic involvement in the control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system. Endocrinology, 111:273-279, 1982.

Armstrong, W.E. and C.D. Sladek. Spontaneous "phasic-firing" in supraoptic neurons recorded from hypothalamo-neurohypophysial explants in vitro. Neuroendocrinology 34:405-409, 1982.

Sladek, C.D., M.L. Blair and D.J. Ramsay. Further studies on the role of angiotensin in the osmotic control of vasopressin release by the organ cultured rat hypothalamo-neurohypophyseal system. Endocrinology, 111:599-607, 1982.

Sladek, C.D. and T.H. McNeill. The Brattleboro-heterozygote rat as a model for neurohypophyseal aging: Vasopressin response to dehydration. Annals of New York Acad. Sci., 394:173-176, 1982.

Sladek, J.R. and C.D. Sladek. Anatomical reciprocity between magnocellular peptides and noradrenalin in putative cardiovascular pathways. Progress in Brain Research, 60:437-443, 1983.

Sladek, C.D. and A.K. Johnson. The effect of anteroventral third ventricle lesions on vasopressin release by organ cultured hypothalamo-neurohypophyseal explants. Neuroendocrinology, 37:78-84, 1983.

Notter, M.F.D., D.M. Gash, C.D. Sladek, and S.L. Scharoun. Vasopressin in reaggregated cell cultures of the developing hypothalamus. Brain Res. Bull., 12:307-313, 1984.

Gregg, C.M. and C.D. Sladek. A compartmentalized, organ-cultered hypothalamo-neurohypophysial system for the study of vasopressin release. Neuroendocrinology, 38:397-402, 1984.

Sladek, C.D. and M.L. Blair. Cholinergic stimulation of vasopressin release in spontaneously hypertensive rats. Hypertension, 6:855-860, 1984.

Armstrong, W.E. and C.D. Sladek. Evidence for excitatory actions of histamine on supraoptic neurons in vitro: Mediation by an H1-type receptor. Neuroscience 16:307-322, 1985.

Sladek, C.D., M.L. Blair, Y.H. Chen, and R.W. Rockhold. Vasopressin and renin response to plasma volume loss in spontaneously hypertensive rats. Am. J. Physiol: Heart Circ. Physiol., 250:H443-H452, 1986.

Sladek, J.R., B.J. Davis and C.D. Sladek. Localization of vasopressin-neurophysin and norepinephrine in the supraoptic nucleus of spontaneously hypertensive rats. Brain Research 365:293-304, 1986.

Herman, J.P., C.D. Sladek, C.T. Hansen and D.M. Gash. Characterization of a new rodent model of diabetes insipidus: The Roman high avoidance rat homozygous for diabetes insipidus. Neuroendocrinology 43:340-347, 1986.

Aravich, P.F. and C.D. Sladek. Vasopressin and glucoprivic-feeding behavior: A new perspective on an old peptide. Brain Research, 385:245-252, 1986.

Armstrong, W.E., M.J. Gallagher, and C.D. Sladek. Noradrenergic stimulation of supraoptic neuronal activity and vasopressin release in vitro: Mediation by an alpha-1-receptor. Brain Res., 365:192-197, 1986.

Clough, R.W., P.F. Aravich, and C.D. Sladek. Neonatal monosodium glutamate: Effects on vasopressin, urine output, and systolic blood pressure in male and female rats. Brain Res. Bull. 17:51-58, 1986.

Earnest, D.J. and C.D. Sladek. Model for studying circadian mechanisms: Vasopressin rhythms in suprachiasmatic cultures. Brain Res., 382:129-133, 1986.

Davis, B.J., M.L. Blair, J.R. Sladek, Jr. and C.D. Sladek. Effects of lesions of central catecholamine pathways on blood pressure, fluid balance, and vasopressin and renin responses to blood volume depletion in the rat. Brain Research, 405:1-15, 1987.

Sladek, C.D., M.L. Blair and M. Mangiapane. Evidence against a pressor role for vasopressin in spontaneous hypertension. Hypertension, 9:332-338, 1987.

Sladek, C.D. and W.E. Armstrong. GABA antagonists stimulate vasopressin release from organ-cultured hypothalamo-neurohypophyseal explants. Endocrinology, 120:1576-1580, 1987.

Collier, T.J., D.E. Redmond, Jr., C.D. Sladek, M. Gallagher, R.H. Roth and J.R. Sladek, Jr. Intracerebral grafting and culture of cryopreserved primate dopamine neurons. Brain Research, 436:363-366, 1987

Sladek, C.D., Y.-H. Chen, P.F. Aravich and M.L. Blair. Osmotic regulation of vasopressin and renin release in spontaneously hypertensive rats. Hypertension, 10: 476-483, 1987.

Earnest, D.J. and C.D. Sladek. Circadian vasopressin release from perifused rat suprachiasmatic explants in vitro: Effects of acute stimulation. Brain Research, 422: 398-402, 1987.

Sladek, C.D., M.A. Devine, S.Y. Felten, P.F. Aravich and M.L. Blair. Abnormalities in hypothalamic and neurohypophysial vasopressin content are not a consequence of hypertension in the spontaneously hypertensive rat. Brain Research, 445:39-46, 1988.

Clough, R.W., G.E. Hoffman and C.D. Sladek. Peripuberal development of noradrenergic stimulation of luteinizing hormone-releasing hormone neurosecretion in vitro. Brain Research 446:121-132, l988.

Chen, Y.-H., H. Hisa, K.J. Radke, J.L. Izzo, C.D. Sladek and M.L. Blair. Adrenergic control of renin in euhydrated and water-deprived conscious dogs. Am J. Physiol. 255:E793-E800, 1988.

Stone, C.K., C-S. Liang, N. Imai, S. Sakamoto, C.D. Sladek and W.B. Hood. Short-term hemodynamic effects of vasopressin V1 receptor inhibition in chronic right-sided congestive heart failure. Circulation 78:1251-1259, l988.

Sladek, C.D., M.L. Blair, C. Sterling, and M.L. Mangiapane. Attenuation of spontaneous hypertension in rats by a vasopressin antagonist. Hypertension 12:506-512,l988.

Redmond, D.E., Jr., F. Naftolin, T.J. Collier, C. Leranth, R. Robbins, C.D. Sladek, R.H. Roth, and J.R. Sladek, Jr.. Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys. Science 242:768-771, l988.

Leibowitz, S.F., C.D. Sladek, L. Spencer, and D. Tempel. Endocrine and feeding responses induced by paraventricular nucleus injection of neuropeptide Y, epinephrine and norepinephrine. Brain Res. Bull. 21:905-912, 1988.

Mangiapane, M.L., K.M. Skoog, P. Rittenhouse, M.L. Blair and C.D. Sladek. Lesion of the area postrema region attenuates hypertension in spontaneously hypertensive rats. Circ. Res. 64:129-135, l989.

Elfont, R.M., P.R. Sundaresan, and C.D. Sladek. Adrenergic receptors on cerebral microvessels: Pericyte contribution. Am. J. Physiol. 256:R224-R230, l989.

Armstrong, W.E., C.J. Wilson, M.J. Gallagher, and C.D. Sladek. Quantitative comparisons between the electrical activity of supraoptic neurons and vasopressin release in vitro. J Neuroendo. 1:215-226,1989.

Herman, J.P., M. K.-H. Schafer, C.D. Sladek, R.Day, E.A. Young, H. Akil , and S.J. Watson. Chronic electroconvulsive shock treatment elicits up-regulation of CRF and AVP mRNA in select populations of neuroendocrine neurons. Brain Research 501:235-246, 1989.

Earnest, D.J., C.D. Sladek, D.M. Gash, and S.J. Wiegand. Specificity of circadian function in transplants of the fetal suprachiasmatic nucleus. J. Neuroscience 9:2671-2677, 1989.

Hisa, H., Y.-H. Chen, K.J. Radke, J.L. Izzo, Jr., C.D. Sladek, and M.L. Blair. Adrenergic component of elevated plasma renin activity during dietary sodium restriction in conscious dogs. Am J. Physiol. 256:E863-E871, l989.

Phelps, C.J., S.W. Carlson, and C.D. Sladek. Vasopressin in Aged Rats: Longitudinal studies of vasopressin excretion in Sprague-Dawley and Fischer 344 Strains. Neurobiology of Aging 10:233-239, 1989.

Phelps, C.J., S.W. Carlson, and C.D. Sladek. Effect of surgical deafferentation of the hypothalamic supraoptic nucleus on urinary vasopressin levels in aged rats. Neurobiology of Aging 11:95-104, 1990.

Yagil, Chana and C.D. Sladek. Osmotic stimulation of vasopressin and oxytocin release is rate sensitive. Am J. Physiol. 258 (Regulatory Integrative Comp. Physiol. 27): R492-R500, 1990.

Sladek, C.D. and C. Yagil. Modulation of noradrenergic control of vasopressin release by hypotonicity in organ-cultured hypothalamo-neurohypophyseal explants. J. Neuroendocrinology 2:363-367, 1990.

Zhang, D., M. Gallagher, C.D. Sladek, and H.H. Yeh. Postnatal development of croticotropin releasing factor-like immunoreactive amacrine cells in the rat retina. Dev. Brain Research 51:185-194, 1990.

Clough, R.W., G.E. Hoffman, and C.D. Sladek. Synergistic interaction between opioid receptor blockade and alpha-adrenergic stimulation on luteinizing hormone-releasing hormone (LHRH) secretion in vitro. Neuroendocrinology 51:131-138, 1990.

Silverman, W.F., P.A. Aravich, J.R. Sladek, Jr., and C.D. Sladek. Physiological and biochemical indices of neurohypophyseal function in the aging Fischer rat. Neuroendocrinology 52:181-190, 1990.

Skoog, K.M., M.L. Blair, C.D. Sladek, W.M. Williams and M.L. Mangiapane. Area postrema is essential for maintenance of arterial pressure following hemorrhage in the rat. Am J. Physiology 258:R1472-R1478, 1990.

Powell, K.R., L. Sugarman, A. Eskenazi, K. Woodin, M. Kays, K. McCormick, M. Miller, and C.D. Sladek. Normalization of plasma antidiuretic hormone concentrations in children with meningitis following 24 hours of fluid replacement therapy. J. Pediatrics 117:515-522, 1990.

Stone, C.K., N. Imai, C.D.Sladek, and C.-S. Liang. Attenuation of the pressor response to arginine vasopressin in right-sided congestive heart failure. Am. J. Physiol. 258:H1882-H1888, 1990.

Collier, T.J., C.D. Sladek, M.J. Gallagher, R.W. Gereau IV, and J.E. Springer. A diffusible factor(s) from adult rat sciatic nerve increases the number and neurite outgrowth of cultured embryonic dopamine neurons. J. Neurosci. Res. 27:394-399, 1990.

Steece-Collier, K., T.J. Collier, C.D. Sladek, and J.R. Sladek, Jr. Chronic levodopa impairs morphological development of grafted embryonic dopamine neurons. Exp. Neurology 110:201-208,1990.

Yagil, C. and C.D. Sladek. Effect of extended exposure to hypertonicity on vasopressin mRNA content of hypothalamo-neurohypophyseal explants. Endocrinology 127:1428-1435, 1990.

Leibowitz, S.F., D. Eidelman, J.S. Suh, S. Diaz and C.D. Sladek. Mapping study of noradrenergic stimulation of vasopressin release. Exp. Neurol. 110:298-305, 1990.

Parker, S.L., W.E. Armstrong, C.D. Sladek, C.E. Grosvenor, and W.R. Crowley. Prolactin stimulates the release of oxytocin in lactating rats: Evidence for a physiological role and an action at the neural lobe. Neuroendocrinology 53:503-510, 1991.

Powell, K.R. and C. Sladek. Letter to Editor: Secretion of antidiuretic hormone in children with meningitis. J. Pediatrics 118:996-998, 1991.

Blair, M.L., H. Hisa, C.D. Sladek, K.J. Radke, J.L. Izzo, Jr., and F.M. Gengo. Dual adrenergic control of renin during non-hypotensive hemorrhage in conscious dogs. Am. J. Physiol. 260:E910-E919, 1991.

Earnest, D.J., S.M. Digiorgio, and C.D. Sladek. Effects of tetrodotoxin on the circadian pacemaker mechanism in suprachiasmatic explants in vitro. Brain Res. Bull., 12:677-682, 1991.

Sladek, C.D. and M.J. Gallagher. Vasopressin gene expression in explant and dispersed hypothalamic cultures. Regulatory Peptides 45:47-52, 1993.

Collier, T.J., M.J. Gallagher, and C.D. Sladek. Cryopreservation and storage of embyonic rat mesencephalic dopamine neurons for one year: Comparison to fresh tissue in culture and neural grafting. Brain Research 632:249-256, 1993.

Sladek, C.D. and M.J. Gallagher. The Stimulation of Vasopressin Gene Expression in Cultured Hypothalamic Neurons by Cyclic AMP is Reversible. Endocrinology, 133:1320-1330, 1993.

Sladek, C.D. and J.A. Olschowka. Dehydration Induces Fos, But Not Increased Vasopressin mRNA in the Supraoptic Nucleus of Aged Rats. Brain Research 652:207-215, 1994.

Ghosh, R. and C.D. Sladek. Role of Prolaction and Gonadal Steroids in the Regulation of Oxytocin mRNA during Lacation. Am. J. Physiology: Endocrinology and Metabolism 269:E76-E84, 1995.

Kim, D., C.D. Sladek, C. Aguado-Velasco, and J.R. Mathiasen. Arachidonic acid activates a distinct family of K+channels in cultured neuronal cells. J. Physiology 484:643-660, 1995.

Ghosh, R. and C.D. Sladek. Prolactin modulates oxytocin mRNA during lactation by its action on the hypothalamo-neurohypophyseal axis. Brain Research 672:24-28, 1995.

Sladek, C.D., K.Y. Fisher, H.E. Sidorowicz, J.R. Mathiasen. Osmotic stimulation of vasopressin mRNA content in the supraoptic nucleus requires synaptic activation. Am. J. Physiology: Regulatory, Integrative, and Comparative, 268:R1034-R1039, 1995.

Mathiasen, J.R., E.R. Larson, M.A. Ariano, and C.D. Sladek. Neurophysin expression is Stimulated by Dopamine D1 Agonist in Dispersed Hypothalamic Cultures. Am. J. Physiology: Regulatory, Integrative, and Comparative 270:R404-R412, 1996.

Sladek, C.D., K.Y. Fisher, H.E. Sidorowicz, J.R. Mathiasen. cAMP regulation of vasopressin mRNA content in hypothalamo-neurohypophyseal explants. Am. J. Physiology: Regulatory, Integrative, and Comparative 271:R554-R560, 1996.

Mathiasen, J.R., D. Maciejewski-Lenoir, F.E. Bloom, and C.D. Sladek. Increased vasopressin secretion from hypothalamic cultures following administration of exogenous vasopressin mRNA. Experimental Neurology 141:165-172, 1996.

Papanek, P.E., C.D. Sladek, and H. Raff. Corticosterone inhibition of osmotically-stimulated vasopressin release from hypothalamic-neurohypophysial explants. Am. J. Physiology: Regulatory, Integrative, and Comparative 272:R158-R162, 1997.

Ludwig, M., M. Morris, and C.D. Sladek. Antisense oligodeoxynucleotides block osmotic, but not KCl stimulated vasopressin and oxytocin release from hypothalamo-neurohypophyseal explants. Am. J. Physiology: Regulatory, Integrative, and Comparative 272:R1441-1446, 1997.

Swenson, K.L. and C.D. Sladek. Gonadal steroid modulation of vasopressin secretion in response to osmotic stimulation. Endocrinology 138:2089-2097, 1997.

Alexander,T., C.E. Sortwell, C.D. Sladek, R.H. Roth, and K. Steece-Collier. Comparison of neurotoxicity following repeated administration of L-dopa, D-dopa, and dopamine to embryonic mesencephalic dopamine neurons in cultures derived from Fisher 344 and Sprague-Dawley donors. Cell Transplantation 6:309-315, 1997.

Swenson, K.L., J. M. Sands, J.D. Jacobs, and C.D. Sladek. Effect of aging on the vasopressin and aquaporin responses to dehydration in Fischer 344/Brown-Norway F1 Rats. Am. J. Physiology: Regulatory, Integrative, and Comparative, 273:R35-R40, 1997

Cohen, B.R. and C.D. Sladek. Expression of floor plate in dispersed mesencephalic cultures: Role in differentiation of tyrosine hydroxylase neurons. Exp. Neurology, 147:525-531, 1997.

Swenson, K.L., S.E. Badre, D.J. Morsette, and C.D. Sladek. N-methyl-D-aspartic acid (NMDA) stimulated vasopressin release and its modulation by gonadal steroids. J. Neuroendocrinology 10:679-685, 1998.

Sladek, C.D., S. E. Badre, and H.E. Sidorowicz. Role of non-NMDA receptors in osmotic and glutamate stimulation of vasopressin release: Effect of rapid receptor desensitization. J. Neuroendocrinology 10:897-903, 1998.

Catudioc-Vallero, J., J.M. Sands, J.D. Klein, H.E. Sidorowicz, and C.D. Sladek. Effect of age and testosterone on the vasopressin and aquaporin responses to dehydration in Fischer 344/Brown-Norway F1 Rats. J. Gerontology:Biological Sciences 55A:B26-B34, 2000.

Sladek, C.D., K.L. Swenson, R. Kapoor, and H.E. Sidorowicz. Role of steroid hormones in regulation of vasopressin and oxytocin release and mRNA expression in hypothalamo-neurohypophyseal explants. Experimental Physiology 85S:171-178, 2000.

Kapoor, J.R. and C.D. Sladek, Purinergic and Adrenergic Agonists Synergize in Stimulating Vasopressin and Oxytocin Release. J. Neuroscience 20: 8868-8875, 2000.

Song, Z., H.E. Sidorowicz, and C.D. Sladek. cAMP Stimulation of Vasopressin and Oxytocin Release and Regulation of Vasopressin mRNA Stability: Role of Auto-Facilitation. J. Neuroendocrinol.13:158-165, 2001.

Morsette D.L., H.E. Sidorowicz, and C.D. Sladek. Role of Non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophyseal explants. Am. J. Physiol.Reg. Integrative Comp. Physiol. 280:R313-R322, 2001.

Kapoor, J.R. and C.D. Sladek, Substance P and NPY differentially potentiate ATP and Adrenergic Stimulated Vasopressin and Oxytocin Release. Am. J. Physiol. 280:R69-R78, 2001.

Morsette, D.L., H.E. Sidorowicz, and C.D. Sladek. Role of Metabotropic Glutamate Receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophyseal explants. Am. J. Physiol. 281:R452-R45, 2001.

Song, Z. and C.D. Sladek. Effect of Forskolin and Exogenously Administered Oxytocin mRNA on Oxytocin Release by Dispersed Hypothalamic Cultures. Experimental Neurology 171:246-254, 2001.

Somponpun, S. and C.D. Sladek. Role of Estrogen Receptor-b (ER-b) in Regulation ofVasopressin and Oxytocin Release in Vitro. Submitted, 1/18/02.

CONTENTS

SELECTED REVIEWS:

Sladek, C.D. Regulation of vasopressin release by neurotransmitters, neuropeptides, and osmotic stimuli. Progress in Brain Research, 60:71-90, 1983.

Sladek, C.D., and W.E. Armstrong. "Osmotic Control of Vasopressin Release." Trends in Neuroscience, 8:166-169, 1985.

Sladek, C.D. and W.E. Armstrong. Effect of neurotransmitters and neuropeptides on vasopressin release. In: Vasopressin: Principles and Properties, ed: D.M. Gash and G.J. Boer, Plenum Publ. Co., pp. 275-333, 1987.

Sladek, C.D. In Vitro Approaches to Neuroendocrinology. In: Methods in Neuroendocrinology. Ed: Louis Van de Kar, CRC Press, pp 69-93, 1998.
Sladek, C.D. Antidiuretic Hormone: Synthesis and Release. In: Handbook of Physiology Section 7: Endocrinology Volume III: Hormonal Regulation of Water and Electrolyte Balance. Ed: John C.S. Fray, Oxford University Press, pp 436-495, 2000.

Sladek, J.R. and C.D. Sladek. Morphology of the endocrine brain, hypothalamus, and neurohypophysis. In: Principles and Practice of Endocrinology and Metabolism. Editor in chief: K.L. Becker, Lippincott Co., 3rd edition, 2000.

Sladek, C.D. and J.R. Kapoor. Neurotransmitter interactions in the hemodynamic regulation of vasopressin release. Experimental Neurology 171:200-209, 2001.