Moshe
Levi, M.D.
Professor of Medicine, Physiology and Biophysics
Vice Chair of Medicine for Research
Head Division of Renal Diseases and
Biomedical
Campus
Tel (303) 315-1541. Lab Tel (303) 315-0466. Fax (303) 315-0189.
EDUCATION
· Northwestern University,
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POST-DOCTORAL TRAINING
· Cornell University Medical College, North Shore University Hospital, Manhasset, NY, and Memorial Sloan Kettering Hospital, New York, NY, Internal Medicine Internship and Residency, 1977-1980
· University of Colorado Health Sciences Center, Denver, CO, Nephrology Clinical and Research Fellowship, 1980-1983
FACULTY POSITIONS
· University of Colorado Health Sciences Center Denver, CO, Instructor in Medicine, July-December 1983
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· University of Zurich Physiology Institute (Professor Heini Murer) Visiting Scientist, June -September 1993
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· University of Colorado Health Sciences
Center,
· University of Colorado Health Sciences
Center,
· Dept. of
· Dept. of
· Dept. of
· Dept of Veterans Affairs Medical Center, Denver, CO, Chief, Nephrology Section, August 2002 - present
BOARD CERTIFICATION
American Board of Internal Medicine:
· Internal Medicine, September 1980
· Nephrology, November 1984
MEMBERSHIPS
· American Association for the Advancement of Science
· American Society of Nephrology
· National Kidney Foundation
· International Society of Nephrology
· American Heart Association
· American Diabetes Association
· Juvenile Diabetes Research Foundation
· American Federation for Clinical Research
· American Physiological Society
· Biophysical Society
· American Society for Biochemistry and Molecular Biology
· American Society for Cell Biology
NATIONAL ADVISORY COMMITTEES
· NIH/NIA: Biology of the Aging Kidney, January 2003
NATIONAL AND LOCAL COMMITTEES
· Member, Long Range Planning Committee, Council on the Kidney in Cardiovascular Disease, American Heart Association, January 2002 - present
· Member, American Heart Association,
Nominating and Awards Committee,
· Member, American Heart Association, High Blood Pressure Research Council, Program Committee, July 1, 1999-present
· President, Region IV, National Kidney Foundation, 1998 – 1999
· Editor-in-Chief, NKF MD, January 1999-2002
· Fellowship Recruitment and Selection, Nephrology Training Program, The University of Texas Southwestern Medical School and Affiliated Programs, July 1, 1995-2002
· Chair, VISN 17 Research Conference,
2000-20018) Member, Search Committee for Chief of Rheumatology, The
· Chairman, Medical Advisory Board, National
Kidney Foundation of
· Member, Medical Advisory Board and Board of
Directors, National Kidney Foundation of
· Member, Research and Development Committee, Dallas VA Medical Center, April 1992 - 2002 Member, VISN 17, Research Committee, July 1, 1996 - 2002
· Chairman, VISN 17, Dialysis Advisory
Committee,
· Chairman, Biomedical Ethics Committee,
· Chairman, Animal Studies Subcommittee,
· Member, Research Space Committee,
· Member, Search Committee for Associate Chief
of Staff for Research,
EDITORIAL BOARD
· American Journal of Physiology: Renal Physiology, 2001-present
· Kidney International, 1997 – present
· American Journal of Kidney Diseases, 2001 – 2002
· American Journal of Physiology: Endocrinology and Metabolism, 1997 - 2002
· American Journal of Physiology: Renal Fluid and Electrolyte Physiology, 1991 to 1996
ABSTRACT REVIEW COMMITTEES
· Abstract Review Committee, 22nd Annual Meeting of the American Society of Nephrology, December 1989
· Abstract Review Committee, 27th Annual Meeting of the American Society of Nephrology, October 1994
· Abstract Review Committee, 30th Annual Meeting of the American Society of Nephrology, November 1997
· Abstract Review Committee, 35th Annual Meeting of the American Society of Nephrology, November 2002
· Abstract Review Committee, 36th Annual Meeting of the American Society of Nephrology, November 2003
GRANT REVIEW COMMITTEES
· Grant Review Committee, National Kidney Foundation, Young Investigator Award Review Committee, December 1991 - 1994.
· Review grants for VA Merit Review.
· Review grants for Swiss National Science Foundation.4) Review grants for Israel Research Foundation.
· Review grants for NIH.
MANUSCRIPT REVIEW
· American Journal of Physiology: Renal
· European Journal of Physiology
· Journal of Clinical Investigation
· Kidney International
· Biochimica & Biophysica Acta
· Endocrinology
· Photochemistry and Photobiology
· American Journal of Gerontology
· Journal of Lipid Research
· Journal of Cell Biology
· Journal of Membrane Biology
· Biochemistry
· American Journal of Physiology: Endocrinology and Metabolism
· Journal of the American Society of Nephrology
· Biophysical Journal
· American Journal of Kidney Diseases
· Journal of Biological Chemistry
· Journal of Laboratory Investigation
INVITED SPEAKER
· University of Zürich, Irchel, Physiology Institute, September 1991
· University of
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· University of Zurich, Irchel, Physiology Institute, July 1995
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· University of Zürich, Irchel, Physiology Institute, July 1996
·
· University of
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·
·
·
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· Hebrew University, Hadassah Medical School, Jerusalem, Israel, Department of Medicine, June 1998
· The
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· Nephrology Forum, Kidney International, Tufts
·
· University of
·
·
· University of
· University of
· University of
· National Institutes of Health, Jan 2003
· National Institute of Aging, Jan 2003
INVITED SPEAKER: NATIONAL AND INTERNATIONAL MEETINGS
· Symposium on Molecular Aspects of Renal Phosphate Transport: Role of Membrane Lipids and Fluidity in Regulation of Renal Phosphate Transport. Annual Meeting of Federation of American Societies for Experimental Biology, April 1991
· Symposium on Renal Phosphate Transport, XIIth International Congress of Nephrology, June 1993
· Forefront Meeting on Phosphate, International Society of Nephrology, September 1995
· Symposium on Regulation of Renal Function by Calcium, National Kidney Foundation Spring Clinical Meeting, April 1999
· Symposium on Regulation of Renal Function in Aging, XVth International Congress of Nephrology, May 1999
· Regulation of Lipid Domains, 4th International Symposium on Innovative Methodologies in Biochemistry and Medicine, June 1999
· Symposium on the Aging Kidney, National Kidney Foundation Spring Clinical Meeting, April 2000
CHAIR SCIENTIFIC SESSIONS NATIONAL AND INTERNATIONAL MEETINGS
· 22nd Annual meeting of the American Society of Nephrology, December 1989: Vitamin D.
· 2nd International Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, September 1991
· XIIth International Congress of Nephrology, June 1993: Symposium on Renal Phosphate Transport.
· 27th Annual meeting of the American Society of Nephrology, October 1994: Calcium-sensing Receptors.
· 3rd International Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, August 1995: Role of cholesterol in regulation of Na/Pi
· 30th Annual meeting of the American Society of Nephrology, November 1997: lycosphingolipids.
· 4th International Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, June 1999: Role of glycosphingolipids in regulation of Na/Pi
· 32nd Annual meeting of the American Society of Nephrology, November 1999: Calcium and Phosphate Metabolism and the Kidney.
· 5th International Symposium on Innovative Fluorescence Methodologies in Biochemistry and Medicine, June 2002: Role of lipid rafts in regulation of Na/Pi transport
RESEARCH INTERESTS
Regulation of Renal Phosphate Transport:
a) Cellular mechanisms of post-translational regulation of Na/Pi by trafficking
and lipid rafts
b) Coordinate regulation of brain and renal Na/Pi (in collaboration with Susan
Mulroney at Georgetown University)
Role of Lipids in Regulation of Cell Function:
a) Role of cholesterol and glycosphingolipids in regulation of membrane
microdomains, lipid rafts and Na/Pi
Pathogenesis and Prevention of Diabetic Renal Disease:
a) Role of lipids and lipotoxicity in the pathophysiology of diabetic
nephropathy
b) Role of sterol regulatory element binding proteins (SREBP-1 and SREBP-2) and
peroxisome proliferator-activated receptors (PPAR-alpha and PPAR-gamma in
diabetic nephropathy
Pathogenesis and Prevention of Age-Related Renal Disease
a) Role of lipids and lipotoxicity in the pathophysiology of diabetic
nephropathy
b) Role of sterol regulatory element binding proteins (SREBP-1 and SREBP-2) and
peroxisome proliferator-activated receptors (PPAR-alpha and PPAR-gamma in
diabetic nephropathy
Clinical Application of Near Infrared Spectroscopy
a) Peripheral Vascular Disease (in collaboration with Enrico Gratton and
Beniamino Barbieri)
b) Brain Imaging (in collaboration with Enrico Gratton)
INVESTIGATIVE REPORTS
1. Levi M, Peterson L, Berl T: Mechanism of Concentrating Defect in
Hypercalcemia: Role of Polydipsia and Prostaglandins. Kidney Int 23:489-497,
1983
2. Levi M, Ellis M, Berl T: Control of Renal Hemodynamics and Glomerular
Filtration Rate in Chronic Hypercalcemia: Role of Prostaglandins,
Renin-Angiotensin System and Calcium. J Clin Invest 71:1624-1632, 1983
3. Burke TJ,
4. Berl T, Levi M, Chaimovitz C, Ellis M: Mechanism of Acute Hypercalcemic
Hypertension in the Conscious Rat: Role of Vasoactive Hormones and Calcium.
Hypertension 7: 923-930, 1985
5. Levi M, Molitoris BA, Burke TJ, Schrier RW, Simon FR: Effects of Vitamin D
induced-Hypercalcemia on Rat Renal Cortical Brush Border and Basolateral
Membranes and Mitochondria. Am J Physiol 252 (Renal Fluid and Electrolyte
Physiol 21): F267-275, 1987.
6. Levi M, Jameson DM, van der Meer BW: Role of Brush Border Membrane Lipid
Composition and Fluidity in Impaired Renal Phosphate Transport in the Aged Rat.
Am J Physiol 256 (Renal Fluid and Electrolyte Physiol 25): F85-F94, 1989.
7. Levi M: Clinical Disorders of Renal Tubular Phosphate Transport. Am J Med
Sci 298: 194-205,1989
8. Levi M, Baird B, Wilson P: Cholesterol Modulates Rat Renal Brush Border
Membrane Phosphate Transport. J Clin Invest 85:231-237, 1990
9. Levi M, Cronin RE: Early Selective Effects of Gentamicin on Renal Brush
Border Membrane Na-Pi Cotransport and Na/H Exchange. Am J Physiol 258 (Renal
Fluid and Electrolyte Physiol 27): F1379-F1387, 1990.
10. Levi M: Heterogeneity of Phosphate Transport by Brush Border Membranes From
Superficial and Juxtamedullary Cortex of the Rat. Am J Physiol 258 (Renal Fluid
and Electrolyte Physiol 27): F1616-F1624, 1990.
11. Levi M: Primary Hyperaldosteronism. Am J Med Sci 300:189-202,1990
12. Moe OW, Tejedor A, Levi M, Seldin DW, Preisig PA, Alpern RJ: Dietary NaCl
Modulates Na/H Antiporter Activity in Renal Cortical Apical Membrane Vesicles.
Am J Physiol 260 (Renal Fluid and Electrolyte Physiol (29): F130-F137, 1991.
13. Henrich WL, Levi M: Ontogeny of Renal Renin Release in the Spontaneously
Hypertensive and Wistar Kyoto Rat. Am J Physiol 260 (Renal Fluid and
Electrolyte Physiol 29): F530-F535, 1991.
14. Levi M, Henrich WL: Dietary Calcium Modulates Renal BBM Angiotensin II
Binding and Na/H Antiporter Activity in SHR. Am J Physiol 260 (Renal Fluid and
Electrolyte Physiol 29): F567-F662, 1991.
15. Levi M, McDonald LA, Preisig PA, Alpern RJ: Chronic K Depletion Stimulates
Rat Renal Brush-Border Membrane Na-Citrate Cotransporter. Am J Physiol 261
(Renal Fluid and Electrolyte Physiol 30): F767-F773, 1991.
16. Levi M: The Molecular Mechanisms of Regulation of Renal Phosphate Transport
by Dietary Phosphate, Parathyroid Hormone, and Vitamin D. In Goldfarb S and
Ziyadeh FN: Hormones Autacoids and the Kidney, Contemporary Issues in
Nephrology Volume 23,
17. Levi M,
18. Loghman-Adham M, Levi M: Phosphonoformic Acid Blunts the Adaptive Response
of Renal and Intestinal Pi Transport. Am J Physiol 265 (Renal Fluid and
Electrolyte Physiol 34): F756-F763, 1993.
19. Levi M, Arar M, Kaissling B, Murer H, Biber J: Low Pi Diet Increases the
Abundance of an Apical Protein Related to Na-Pi Cotransport in Rat Proximal
Tubular S3 Segments. European Journal of Physiology (Molecular and Cellular
Physiology) 426:5-11, 1994
20. Arar M, Levi M, Baum M: Maturational Effects of Glucocorticoids on Neonatal
Brush Border Membrane Phosphate Transport. Pediatric Research 35:474-478, 1994
21. Loghman-Adham M, Motock G, Levi M: Enhanced Bioavailability of
Phosphonoformic Acid by Dietary Phosphorus Restriction. Biochemical
Pharmacology 48: 1455-1458, 1994
22. Levi M, Lötscher M, Sorribas V, Custer M, Arar M, Kaissling B, Murer H,
Biber J: Cellular Mechanisms of Acute and Chronic Adaptation of Rat Renal
Phosphate Transporter to Alterations in Dietary Phosphate. Am J Physiol 267
(Renal Fluid Electrolyte Physiol 36): F900-F908, 1994.
23. Arar M, Baum M, Biber J, Murer H, Levi M: Epidermal Growth Factor Inhibits
Na-Pi Cotransport and mRNA in OKP Cells. Am J Physiol 268 (Renal Fluid
Electrolyte Physiol 37): F309-F314, 1995.
24. Kempson SA, Lötscher M, Kaissling B, Biber J, Murer H, Levi M: Effect of
Parathyroid Hormone on Phosphate Transporter mRNA and Protein in Rat Renal
Proximal Tubules. Am J Physiol 268 (Renal Fluid Electrolyte Physiol 37):
F784-791, 1995.
25. Loghman-Adham M, Motock GT, Wilson P, Levi M: Characterization of
Na-Phosphate Cotransporters in Renal Cortical Endosomes. Am J Physiol 269
(Renal Fluid Electrolyte Physiol. 38): F93-F102, 1995.
26. Levi M, Shayman J, Abe A, McCluer RH, Gross SK, Biber J, Murer H, Lötscher
M, Cronin RE: Dexamethasone Modulates Rat Renal Brush Border Membrane Phosphate
Transporter mRNA and Protein Abundance and Glycosphingolipid Composition. J Clin
Invest 96: 207-216, 1995
27. Maier JS, Barbieri B, Chervu A, Chervu I, Fantini S, Franceschini MA, Levi
M, Mantulin WW, Rosenberg A, Walker SA, Gratton E: In Vivo Study of Human
Tissues With a Portable Near-Infrared Tissue Spectrometer. Proc. of SPIE 2387:240-248,
1995
28. Lötscher M, Kaissling B, Biber J, Murer H, Kempson SA, Levi M: Regulation
of Rat Renal Na/Pi-Cotransporter by Parathyroid Hormone: Immunohistochemistry.
Kidney Int. 49:1010-1011, 1996
29. Lötscher M, Nguyen S, Wilson P, Kaissling B, Biber J, Mürer H, Levi M: New
Aspects In The Regulation of Renal Phosphate Transport by Dietary Phosphate.
Kidney Int. 49:1012-1018, 1996
30. Murer H, Lötscher M, Kaissling B, Levi M, Kempson SA, Biber J: Renal Brush
Border Membrane Na/Pi-Cotransport: Molecular Aspects in PTH-Dependent and
Dietary Regulation: Kidney Int. 49:1769-1773, 1996.
31. Sorribas V, Lötscher M, Loffing J, Biber J, Kaissling B, Murer H, Levi M:
Cellular Mechanisms of the Age-Related Decrease in Renal Phosphate
Reabsorption. Kidney Int. 50: 855-863, 1996
32. Levi M, Kempson SA, Lötscher M, Biber J, Murer H: Molecular Regulation of
Renal Phosphate Transport. J. Membrane Biol. 154:1-9, 1996.
33. Prabu S, Levi M, Dwarakanath V, Arar M, Biber J, Murer H, Baum M: Effect of
Glucocorticoids on Neonatal Rabbit Renal Cortical Na/Pi mRNA and Protein
Abundance. Pediatric Research 42:20-24, 1997
34. Wang H, Zajicek H, Kumar V, Wilson P, Levi M: Role of Cholesterol in the
Regulation of Renal Phosphate Transport. Frontiers in Bioscience 2:43-48, 1997
35. Parasassi T, Gratton E, Yu W, Wilson P, Levi M: Two-Photon Fluorescence
Microscopy of LAURDAN GP-Domains in Model and Natural Membranes. Biophysical J
72: 2413-2429, 1997
36. Levi M, Wilson P, Nguyen S, Iorio E, Sapora O, Parasassi T: In K562 and
HL60 Cells Membrane Ageing During Cell Growth is Associated with Changes in
Cholesterol Concentration. Mech Aging and Development 97: 109-119, 1997
37. Lötscher M, Biber J, Murer H, Kaissling B, Levi M: Role of Microtubules in
the Rapid Upregulation of Rat Renal Proximal Tubular Na-Pi Cotransport
Following Dietary Pi Restriction. J Clin Invest 99: 1302-1312, 1997
38. Zajicek H, Wang, H, Kumar V, Wilson P, Levi M: Role of Glycosphingolipids
in the Regulation of Renal Phosphate Transport. Kidney Int. Vol. 52, Suppl. 61:
S32-S35, 1997.
39. Shimabukuro M, Zhou Y, Levi M, Unger R: Fatty Acid-Induced (-cell
Apoptosis: A Link Between Obesity and Diabetes. Proc. Natl Acad. Sci,
40. Ambühl P, Zajicek HK, Wang H, Puttaparthi K, Levi M: Regulation of Renal
Phosphate Transport by Acute and Chronic Metabolic Acidosis in the Rat. Kidney
Int. 53:1288-1298, 1998
41. Markovich D, Biber J, Murer H, Sakhaee K, Pak C, Levi M: Dietary Sulfate
Regulates Rat Renal Sulfate Transport. J Am Soc Nephrol 9:1568-1573, 1998.
42. Loffing J, Lötscher, Kaissling B, Biber J, Murer H, Seikaly M, Alpern R,
Levi M, Baum M, Moe O: Renal Na/H Exchanger NHE-3 and Na-PO4 Cotransporter
NaPi-2 Protein Expression in Glucocorticoid Excess and Deficient States. J Am
Soc Nephrol 9:1560-1567, 1998.
43. Arar M, Zajicek HK, Levi M: Epidermal Growth Factor Inhibits Na-Pi
Cotransport in Weaned and Suckling Rats. Am J Physiol 276: 72-78,1999
44. Markovich D, Wang H, Puttaparthi K, Zajicek HK, Rogers T, Murer H, Biber J,
Levi M: Chronic K Depletion Inhibits the Rat Renal Brush-Border Membrane
Na/Sulfate Cotransporter NaSi-1. Kidney International 55:244-251, 1999
45. Alcalde AI, Sarasa M, Morales R, Aramayona U, Biber J, Murer H, Levi M,
Sorribas V: Role of Thyroid Hormone in Regulation of Renal Phosphate Transport
in Young and Aged Rats. Endocrinology 140:1544-1551, 1999
46. Puttaparthi K, Markovich D, Halaihel N, Wilson P, Zajicek HK, Wang H, Biber
J, Murer H, Rogers T, Levi M: Metabolic Acidosis Regulates Rat Renal
Na/Si-Cotransport Activity. American Journal of Physiology 276 (Cell Physiol
45): C1398-C1404, 1999
47. Choudhury D, Michener B, Fennelly P, Levi M: Near Infrared Spectroscopy in
the Early Detection of Peripheral Vascular Disease. J Vascular Technology, 23:
109-113, 1999
48. Choudhury D, Michener B, Fennelly P, Levi M: Near Infrared Spectroscopy in
the Evaluation of Lower Limb Ischemia in Hemodialysis Patients. J Vascular
Technology,
49. Parasassi T, Gratton E, Zajicek H, Levi M, Yu W: Detection of Membrane
Lipid Microdomains by Two-Photon Fluorescence Microscopy. IEEE Engineering in
Medicine and Biology 18: 92-99, 1999
50. Wallace M, Michener B, Choudhury D, Levi M, Fennely P, Hueber DM, Barbieri
B: Summary of the Results of a 95 Subject Human Clinical Trial for Diagnosis of
Peripheral Vascular Disease Using a Near Infrared Frequency Domain Hemoglobin
Spectrometer. Proc of SPIE, 3597: 300-316, 1999
51. Lötscher M, Scarpetta Y, Levi M, Halaihel N, Wang H, Zajicek HK, Biber J,
Murer H, Kaissling B: Rapid Downregulation of Rat Renal Na/Pi-Cotransporter in
Response to Parathyroid Hormone involves Microtubule Rearrangement. J Clin
Invest 104: 483-494, 1999
52. Raj DSC, Choudhury D, Welbourne TC, Levi M: Advanced Glycation End
Products: A Nephrologist’s Perspective. Am J Kid Dis 35:365-380, 2000
53. Levi M: Journal Club Review: Npt2 Is the Major Mediator of Renal Phosphate
Transport. Am J Kid Dis 36:1276-1280, 2000.
54. Woda C, Mulroney SE, Halaihel N, Sun L, Wilson P, Levi M, Haramati A: Renal
Tubular Sites of Increased Phosphate Transport and NaPi-2 Expression in the
Juvenile Rat. Am J Physiol Regul Integr Comp Physiol 280:R1524-1533, 2001
55. Sorribas V, Halaihel N, Alcalde AI, Morales RM, Sarasa M, Zajicek HK, Wang
H, Rogers T, Puttaparthi K, Cronin RE, Levi M: Gentamicin causes endocytosis of
Na/Pi cotransporter protein (NaPi-2). Kidney Intl 59:1024-1036, 2001
56. Dietrich C, Bagatolli L, Thompson N, Levi M, Jacobson K, Gratton E. Lipid
rafts reconstituted in model membranes. Biophysical Journal 80: 1417-1428, 2001
57. Haviv YS, Wald H, Levi M, Dranitzki-Elhalel M, Popovtzer MM. Late onset
down-regulation of NaPi-2 in experimental Fanconi’s syndrome. Pediatric
Nephrology 16:412-416, 2001
58. Levi M: Nephrology Forum: Posttransplant Hypophosphatemia. Kidney
International 59:2377-2387, 2001
59. Friedlaender MM, Wald H, Dranitzki-Elhalel M, Zajicek H, Levi M, Popovtzer
MM. Vitamin D reduces renal NaPi-2 in PTH-infused rats: Complexity of vitamin D
action on renal Pi handling. Am J Physiol, 281:428-433, 2001
60. Zajicek H, Wang H, Puttaparthi K, Halaihel N, Markovich D, Shayman J,
Beliveau R, Wilson, P, Rogers T, Levi M: Glycosphingolipids Modulate Renal
Phosphate Transport in Potassium Deficiency. Kidney International, 60:694-704,
2001
61. Green J, Debby H, Lederer E, Levi M, Zajicek HK, Bick T. Evidence for
PTH-independent humoral mechanism in post-transplant hypophosphatemia and
phosphaturia. Kidney International, 60:1182-1196, 2001
62. Dietrich C, Volovyk ZN, Levi M, Thompson NL, Jacobson K: Partitioning of
Thy-1, GM1 and cross-linked phospholipid analogs into lipid rafts reconstituted
in model membrane monolayers. Proc Natl Acad Sci USA 98:10642-10647, 2001.
63. Raj D, Vincent B, Simpson K, Sato E, Jones KL, Welbourne TC, Levi M, Shah
V, Blandon P, Zage P, Robbins RA. Hemodynamic changes during hemodialysis: Role
of nitric oxide and endothelin. Kidney International 61:697-704, 2002
64. Sun L, Halaihel N, Zhang W,
65. Sadjadi J, Puttaparthi K, Li L, Welborn MB, Rogers TE, Moe O, Clagett GP,
Turnage RH, Levi M, Modrall JG. Upregulation of autocrine-paracrine
renin-angiotensin systems in chronic renovascular hypertension. J Vasc Surgery,
36: 386-392, 2002
66. Wolf U, Wolf M, Choi J, Levi M, Choudhury D, Hull S, Coussirat D, Paunescu
A, Safanove LP, Michalos A, Mantulin WW, Gratton E. Localized irregularities in
hemoglobin flow and oxygenation in the calf muscle in patients with peripheral vascular
disease detected by near-infrared spectrophotometry. J Vascular Surgery, in
press
67. Amanzadeh J, Gitomer WL, Zerwekh JE, Preisig PA, Moe OW, Pak CYC, Levi M.
Effect of high protein diet on stone-forming propensity and bone loss in rats.
Kidney International, in press
68. Friedlaender MM, Wald H, Rubinger D, Levi M, Popovtzer MM. IGF-1 increases
renal cortex NaPi-2 mRNA expression and protein content in intact rats but not
after ischemic ARF. Am J Physiol, Submitted for publication (in revision)
69. Woda C, Halaihel N, Haramati A, Levi M, Mulroney SE: Regulation of NaPi-2
expression and tubular phosphate reabsorption by growth hormone in the juvenile
rat. Submitted for publication (in revision)
70. Mulroney SE, Woda CB, Halaihel N, Louie B, McDonnell K, Schulkin J,
Haramati A, Levi M. Regulation of Type-II Sodium-Phosphate (NaPi-2)
Transporters in the Brain: Central Control of Renal NaPi-2 Transporters:
Submitted for Publication (in revision)
71. Elhalel-Dranitzki M, Wald H, Rubinger D, Gai-Moscovici A, Levi M, Popovtzer
MM. Regulation of NaPi-2 mRNA and Transporter Protein in Chronic Renal Failure:
Role of Parathyroid Hormone (PTH) and Dietary Phosphate (Pi): Submitted for
Publication (in revision)
72. Sun L, Zhang W, Halaihel N, Wilson P, Levi M. Free Fatty Acids Stimulate
Proliferation of Mouse Mesangial Cells through a PKC and MAPK-dependent
pathway: Submitted for publication (in revision)
73. Zajicek H, Halaihel N, Sun L, Zhang W, Wilson P, Mirzaei S, Rogers T, Levi
M. Troglitazone modulates renal phosphate transport and type II Na/Pi
cotransporter protein in Zucker Diabetic Fatty rats: Submitted for publication
(in revision)
74. Halaihel N, Sun L, Rogers T, Zajicek H, Wilson P, Zhou Y-T, Levi M.
Troglitazone modulates lipid composition and glomerulosclerosis in Zucker
Diabetic Fatty Rats. Submitted for publication
75. Zajicek HK, Halaihel N, Sun L, Mirzaei S, Green J, Penfield J, Levi M.
Acute upregulation of Npt2 in proximal tubular BBM is associated with increased
excretion of Npt2 in the urine. Submitted for publication (in revision)
76. Zajicek H, Halaihel N, Parasassi T, Gratton E, Lederer E, Levi M:
Cholesterol Modulates Na/Pi Cotransport Activity and Na/Pi protein expression
in OK Cells. Submitted for publication (in revision)
77. Rubinger D, Wald H, Gimelreich D, Halaihel N, Rogers T, Levi M, Popovtzer
MM. Acute Renal Failure Due to Ischemia and Reperfusion Modulates Renal
Phosphate Transport and Expression of Npt2 mRNA and Protein: Submitted for
publication (in revision)
78. Halaihel N, Traebert M, Zajicek HK, Kaissling B, Levi M: Gentamicin causes
rapid lysosomal targeting of the Type II NaPi cotransport protein: Submitted
for publication (in revision)
79. Zajicek H, Wang H, Halaihel N, Sun L, Lederer E, Levi M: Ceramide and
Sphingosine-1-phosphate Regulate Na/Pi Cotransport Activity in OK Cells: In
preparation
BOOK CHAPTERS
1. Levi M, Berl T: Water Metabolism. In Gonick HC (Ed.): Current Nephrology
Vol. 5,
2. Levi M, Bichet DG, Berl T: Treatment of Hypoosmolar and
3. Bichet DG, Levi M, Schrier RW: Polyuria, Dehydration, Overhydration. In
Seldin DW, Giebisch G (eds.): The Kidney, Physiology and Pathophysiology,
4. Levi M, Berl T: Water Metabolism. In Gonick HC (ed.): Current Nephrology
Vol. 9,
5. Levi M, Rowe JW: Aging and the Kidney. In Schrier RW and Gottschalk CW
(ed.): Diseases of the Kidney, 4th ed.,
6. Diamond SM, Levi M: Renal and Genitourinary Complications from the Treatment
of Hodgkin’s Disease. In Lacher MJ and Redman JR (Eds.): Hodgkin’s Disease: The
Consequences of Survival,
7. Levi M, Knochel JP: The Management of Disorder of Phosphate Metabolism. In
Massry SG and Suki WN (Eds.): Therapy of Renal Diseases and Related Disorders.
8. Levi M, Schrier RW: Renal Disease in the Elderly. In Schrier RW (Ed.):
Geriatric Medicine: The Care of the Elderly. WB Philadelphia, Saunders Co.,
1990.
9. Levi M, Rowe JW: The Pathophysiology of the Aging Kidney. In Seldin DW and
Giebisch G (Eds.): The Kidney: Physiology and Pathophysiology, 2nd Ed.
10. Levi M, Cronin E, Knochel JP: Disorders of Phosphate and Magnesium
Metabolism. In
11. Rowe JW, Minaker KL, Levi M: Pathophysiology and Management of Electrolyte
Disturbances in the Elderly. In Martinez-Maldonado M. (ed.): Hypertension and
Renal Disease in the Elderly.
12. Levi M, Rowe JW: Aging and the Kidney. In Schrier RW and Gottschalk CW
(eds): Diseases of the Kidney, 5th ed.,
13. Levi M: Aging in the Kidney. In Regenbogen LS and Eliahou HE (Eds): Disease
Affecting the Eye and the Kidney,
14. Agarwal R, Levi M: Selection of Therapy for End Stage Renal Disease
Patient. In Henrich W L (ed.): The Principles and Practice of Nephrology,
15. Palmer BF, Levi M: Kidney Disease in the Elderly. In: R. Schrier, D
Jahnigen, (Eds.), Geriatric Medicine. 3rd edition,
16. Palmer BF, Levi M: Effect of Aging on Renal Function and Disease. In: BM
Brenner, FC Rector, (Eds.), The Kidney. 5th Edition, WB Saunders, 1996.
17. Levi M, Peterson LN: Disorders of Potassium Metabolism. In Schrier RW (Ed):
Renal and Electrolyte Disorders, 5th Edition,
18. Palmer BF, Levi M: Aging and the Kidney. In Schrier RW and Gottschalk CW
(Eds.): Diseases of the Kidney, 6th Ed,
19. Levi M, Popovtzer M: Phosphate Metabolism – In Atlas of Diseases of the
Kidney. Schrier RW and Berl T (Eds.), Disorders of Water, Electrolytes, and
Acid Base, 1999
20. Dev D, Palmer BF, Levi M: The Pathophysiology of the Aging Kidney. In
Seldin DW and Giebisch G (Eds): The Kidney: Physiology and Pathophysiology, 3rd
Ed.
21. Dev D, Raj D, Palmer BF, Levi M: Effect of Aging on Renal Function and
Disease. In BM Brenner (Ed): The Kidney. 6th Edition, WB Saunders, 2000
22. Penfield J, Dev D, Cronin E, Knochel JP and Levi M: Disorders of Phosphate
and Magnesium Metabolism. In Favus and Coe (Eds.): Disorders of Bone and
Mineral Metabolism, 2nd Edition, Raven Press, 2000
23. Choudhury D and Levi M: Renal Function and Dysfunction in Aging. In:
Schrier RW (ed): Diseases of the Kidney, 6th Ed,
24. Parasassi T, Bagatolli L, Gratton E, Levi M, Ursini F, Yu W, Zajicek HK.
Two-Photon Excitation Fluorescence Microscopy for Imaging of Lipid Dynamics of
Tissues, Cells, Organelles and Lipid Vesicles while in Physiological
Conditions. In: Confocal and Two-Photon Microscopy: Foundations, Applications
and Advances, Alberto Diaspro Ed., John Wiley & Sons, Inc., In Press
25. Levi M, Zajicek HK, Parasassi T. Spectroscopy and Microscopy of Membrane
Systems. In: Biophotonics, a 2-Volume Issue in Methods in Enzymology. In Press
26. Levi M,
ABSTRACTS PRESENTED AT NATIONAL AND INTERNATIONAL
MEETINGS
1. Goldberg J, Aisenbrey G, Levi M, Berl T, Schrier RW: Common Pathway for Vasoconstrictor
Properties of Angiotensin (AII), Norepinephrine (NE), and Vasopressin (VP). Am
Soc Nephrol (13), 60A, 1980
2. Berl T, Ellis M, Levi M: Mechanism of Hypertension in Acute Hypercalcemia.
Clin Res 29:43A, 1981.
3. Levi M, Ellis M, Berl T: Studies on the Mechanism of the Renal Concentrating
Defect in Chronic Hypercalcemia. Clin Res 29:73A, 1981.
4. Berl T, Ellis M, Goldberg J, Levi M: Mechanism of Hypertension in Acute
Hypercalcemia. Clin Res 29:469A, 1981.
5. Levi M, Ellis M, Goldberg J, Berl T: Studies on the Mechanism of the Renal
Concentrating Defect in Chronic Hypercalcemia. Clin Res 29:469A, 1981.
6. Levi M, Ellis M, Peterson L, Berl T: Studies on the Mechanism of the Renal
Concentrating Defect (RCD) in Chronic Hypercalcemia (HCa). Int Cong Nephrol
(8), RH 059, 1981.
7. Berl T, Chaimovitz C, Ellis M, Goldberg J, Levi M: Mechanism of Hypertension
in Acute Hypercalcemia. Int Cong Nephrol (8), HK 090, 1981.
8. Levi M, Ellis M,
9. Levi M, Ellis M, Berl T: Angiotensin (AII) and Prostaglandin (PG) in the
Control of Renal Hemodynamics in Chronic Hypercalcemia (HCa). Am Soc Nephrol
(14), 117A, 1981.
10. Levi M, Ellis M, Berl T: Prostaglandin (PG) - Angiotensin (AII) Interaction
in the Control of Renal Hemodynamics During Chronic Hypercalcemia (HCa) in
Conscious Rats. Clin Res 30:79A, 1982.
11. Levi M, Ellis M, Berl T: Control of Renal Hemodynamics (RH) in the
Conscious Rat with Chronic Hypercalcemia (HCa). Clin Res 30:456A, 1982.
12. Levi M,
13. Levi M,
14. Burke TJ, Levi M,
15. Shapiro MD, Levi M, Kuruvila KC: High Bicarbonate Peritoneal Dialysis in
Treatment of Severe Metabolic Acidosis Due to Septic Shock. NKF: Clin Dialysis
and Transplant Forum, 1982, p 30.
16. Schrier RW,
17. Levi M, Ellis M, Chaimovitz C, Berl T: Mechanism of Acute Hypercalcemic
(HCa) Hypertension in the Conscious Rat: Role of Vasoactive Hormones and
Calcium. Am Soc Nephrol (16) 66A, 1983.
18. Levi M, Arnold PE, Burke TJ, Schrier RW: Dissociation of Tubular and
Mitochondrial (Mito) Dysfunction in Hypercalcemic (HCa) Acute Renal Failure
(ARF). Int Cong Nephrol (9), 329A, 1984.
19. Levi M, Molitoris B, Burke TJ, Schrier RW, Simon FR: Acute Renal Failure
During Prostaglandin Synthesis Inhibition in Hypercalcemia: Cellular and
Hemodynamic Factors. Int Cong Nephrol, Satellite Symposium on Acute Renal
Failure, 1984.
20. Levi M, Molitoris BA, Schrier RW, Simon FR: Effects of Hypercalcemia on Rat
Renal Cortical Brush Border, Basolateral Membrane and Mitochondria. Clin Res
32, 859A, 1984.
21. Levi M, Molitoris BA, Simon FR: Effects of Hypercalcemia on Renal Cortical
Brush Border and Basolateral Membrane Function and Phospholipid Metabolism.
Clin Res 33:490A, 1985.
22. Levi M, Jameson D, van der Meer W: Impairment of Tubular Reabsorption of
Phosphate by Chronic Hypercalcemia in the Rat. Am Soc Nephrol (18), 14A, 1985.
23. Marconi J, Wilson P, Levi M: Renal Cortical Brush Border and Basolateral
Membrane Phospholipid Compositional Alterations in the Spontaneously
Hypertensive Rat. Am Soc Nephrol (18), 103A, 1985.
24. Wilson P, Marconi J, Levi M: Effects of Dietary Calcium on Blood Pressure
and Na,K-ATPase in the Spontaneously Hypertensive Rat. Am Soc Nephrol (18),
113A, 1985.
25. van der Meer W, Marconi J, Wilson P, Levi M: Effects of Aging on Renal
Cortical Brush Border Membrane Enzyme Activity and Lipid Composition. Am Soc
Nephrol (18), 211A, 1985.
26. Levi M, Marconi J, Wilson P, van der Meer W: Vitamin D-Induced Chronic
Hypercalcemia Impairs Tubular Reabsorption of Phosphate in the Rat. Clin Res
34:205A, 1986.
27. van der Meer W, Wilson P, Marconi J, Levi M: Dietary Calcium Loading
Enhances Tubular Reabsorption of Phosphate in the Rat. Clin Res 34:229A, 1986.
28. Levi M, Wilson P, van der Meer R, Marconi J, van der Meer W: Alterations in
Urinary Calcium Excretion and Cortical Brush Border Membrane Phospholipid
Composition and Fluidity in the Spontaneously Hypertensive Rat. Clin Res
34:481A, 1986.
29. Levi M, Marconi J, van der Meer R, Wilson P, van der Meer W: Effects of
Urinary Calcium on Tubular Reabsorption of Phosphate in the Rat. Clin Res
34:611A, 1986.
30. van der Meer W, Marconi J, Wilson P, van der Meer R, Levi M: Mechanisms of
Impaired Tubular Reabsorption of Phosphate in the Aged Rat. Clin Res 34:611A,
1986.
31. Levi M, Eisenberg S, van der Meer W: Mechanisms of Impaired Tubular
Function in the Aged Rat Kidney. The Gerontologist 26:76A-77A, 1986.
32. van der Meer R, Wilson P, Levi M: The Role of Parathyroid Hormone in the
Enhanced Renal Tubular Calcium Transport in the Spontaneously Hypertensive Rat.
Am Soc Nephrology (19) 155A, 1986.
33. Wilson P, Levi M: The Role of Dietary Calcium and Parathyroid Hormone in
the Control of Arterial Blood Pressure in the Spontaneously Hypertensive Rat.
Am Soc Nephrol (19) 155A, 1986.
34. Levi M, Marconi J, van der Meer W: The Effects of Chronic Hypercalcemia on
Renal Phosphate Metabolism. Am Soc Nephrol (19) 197A, 1986.
35. Levi M, Baird B, Marconi J, Wilson P: The Effects of Dietary Calcium on
Renal Phosphate Transport. Int Cong Nephrol (10) 435, 1987.
36. Baird B, Marconi J, Levi M: Effects of Vitamin D-Induced Hypercalcemia on
Renal Phosphate Transport. Int Cong Nephrol (10) 434, 1987.
37. Levi M, Baird B, Wilson P, Zhu M: In Vivo and In Vitro Hypercalcemia
Modulates Renal Brush Border Membrane Phosphate Transport and Fluidity. Clin
Res 36:522A, 1988.
38. Levi M, Baird B, Wilson P: Dietary Calcium Modulates Renal Brush Border
Membrane Vesicle Na+/H+ Exchange. Clin Res 36:429A, 1988.
39. Baird B, Wilson P, Levi M: In Vitro Cholesterol (Chol) Modulates Renal
Brush Border Membrane (BBM) Fluidity and Phosphate (Pi) Transport. Am Soc
Nephrology 21:2, 1988.
40. Wilson P, Baird B, Levi M: The Role of Brush Border Membrane (BBM)
Phospholipid Composition and Fluidity in the Axial Heterogeneity of Rat Renal
Phosphate (Pi) Transport. Am Soc Nephrology 21:240, 1988.
41. Levi M, Cronin RE, Baird B, Griggs M, Wilson P: Early and Selective Effects
of Gentamicin (G) on Rat Renal Brush Border Membrane (BBM) Sodium-Phosphate
Cotransport (Na-Pi) and Sodium-Hydrogen Exchange (Na/H). Am Soc Nephrology
21:263, 1988.
42. Levi M, Baird B, Wilson P, Griggs M, Cronin RE: Dietary Calcium Protects
Against Gentamicin Nephrotoxicity by Modulating Brush Border Membrane
Sodium-Phosphate Cotransport Activity and Phosphatidylinositol Content. Clin
Res 37:495A 1989.
43. Baird B, Wilson P, Levi M: Mechanism of Gentamicin-Induced Decrease in
Renal Brush Border Membrane Sodium-Phosphate Co-cotransport Activity. Clin Res
37:484A 1989.
44. Moe O, Tejedor A, Levi M, Seldin D, Preisig P, Alpern R: Decreased Dietary
NaCl Increase Na/H Antiporter in Rat Cortical Brush Border Membranes. Clin Res
37:583A 1989.
45. Baird B, Wilson P, Levi M: Mechanism of Regulation of Brush Border Membrane
Na-Pi Cotransport in Chronic Metabolic Acidosis. Am Soc Nephrology 22:265A,
1989.
46. Levi M, Cronin RE: Mechanism of the Axial Heterogeneity of Gentamicin
Toxicity Along the Proximal Tubule. Am Soc Nephrology 22:299A, 1989.
47. Henrich W, McAllister E, Griggs M, Wilson P, Levi M: Renal Renin Release is
Enhanced in the Prehypertensive SHR. Clin Res 38:429A, 1990.
48. Levi M, Wilson P, Griggs M, McAllister E, Henrich W: Dietary Calcium
Modulates Renal Brush Border Membrane Angiotensin II Binding and Na/H
Antiporter Activity in the Prehypertensive SHR. Clin Res 38:428A, 1990.
49. Levi M, McDonald LA, Preisig PA, Alpern RJ: Low Dietary K Stimulates the
Rat Renal Brush Border (BBM) Na/Citrate Cotransporter. J Am Soc Nephrology
1:654, 1990.
50. Arar M, Wilson P, Cooper J, Levi M: Phosphonoformic Acid (PFA) Inhibits Rat
Renal Brush Border Membrane (BBM) Na-Sulfate (Na-SO4) Cotransport activity. J
Am Soc Nephrology 1: 574, 1990.
51. Henrich WL, Levi M: Ontogeny of Renin Secretion (RS) in the Rapp
Salt-Sensitive (SS) and Salt-Resistant (SR) Rat. J Am Soc Nephrology 1: 492,
1990.
52. Levi M, Wilson P, Cooper J: Role of Membrane Fluidity in Adaptation of
Na-Pi Cotransport in Phosphate-Deprived Renal Tubular Cells. Biophysical J
59:651a, 1991.
53. Bansal N, Germann MJ, Cooper J, Levi M, Malloy CR: Effects of Dietary
Phosphate Deprivation on Intracellular Phosphates, Mg+ and pH in the Renal
Cortex. J Magnetic Resonance Imaging, 1991.
54. Arar M, Baum M, Levi M: EGF Inhibits Na-Pi Cotransport in OKP Cells by
Activation of Protein Kinase C and Endocytosis. J Am Soc Nephrology 2:771,
1991.
55. Levi M, Wilson P, Cooper J: Membrane Cholesterol is Decreased and Fluidity
is Increased in MCT Cells Adapted to a Low Phosphate Medium. J Am Soc
Nephrology 2:775, 1991.
56. Loghman-Adham M, Levi M, Motock GT, Scherer SA, Totzke MT: Mechanism of
Blunting of the daptive Response of Na+-Pi Cotransporter by Phosphonoformic
Acid (PFA). J Am Soc Nephrology 3: 686, 1992.
57. Arar M, Levi M, Baum M: Maturation of Na-Pi Transport in Rabbit Proximal
Tubules (PT) - Role of Dexamethasone (DEX). J Am Soc Nephrology 3: 679, 1992.
58. Cooper O, Scott S, Wilson P, Arar M, and Levi M: Chronic K Depletion
Inhibits Rat Renal Brush Border Membrane (BBM) Na-Pi Cotransporter. J Am Soc
Nephrology 3: 682, 1992.
59. Wilson P, Cronin RE, Gross SK, McCluer RH, and Levi M: Glucocorticoids
Modulate Rat Renal Brush Border Membrane (BBM) Na-Pi Cotransporter and BBM
Glycosphingolipid Composition and Fluidity. J Am Soc Nephrology 3: 691, 1992.
60. Levi M, Arar M, Kaissling B, Murer H, and Biber J: Low Pi Diet Increases an
Apical Protein Related to Na-Pi Cotransporter in Rat Proximal Tubule. J Am Soc
Nephrology 3: 839, 1992.
61. Levi M, Jameson D, Wilson P, Cooper J: Effect of Lipid-Protein and
Lipid-Lipid Interactions on Lipid Dynamics and Lipid Phases in Renal Apical
Membranes. Biophysical J. 64: A165, 1993.
62. Levi M, Moe OW, McAllister E, Eskue A, Henrich W: Effect of Urine
nephrectomy (UNX) on The Intrarenal Renin-Angiotensin System (RAS) in the Rat.
J Am Soc Nephrology 4:443, 1993.
63. Chervu I, Scott S, Levi M: Testosterone Increases Kidney Size and
Glycosphingolipid (GSL) in the Female Rat. J Am Soc Nephrology 4:463, 1993.
64. M. Loghman-Adham, M Levi, GT Motock, P Wilson: Difference in Na+-Pi
Cotransporters of Renal Endosomes (EV) and Brush Border Membrane (BBM) 4:710,
1993.
65. Lötscher M, Levi M, Mürer H, Biber J, Kaissling B: Cellular Mechanisms of
Adaptation of Rat Renal Na/Pi-Cotransport to Dietary Phosphate. J Am Soc
Nephrology, 5:869, 1994
66. Levi M, Shayman JA, Biber J, Mürer H, Chervu I: Glycosphingolipids Modulate
Na-Pi Cotransport in Dietary Potassium Deficient (KD) Rats. J Am Soc
Nephrology, 5:868, 1994.
67. Kempson SA, Lötscher M, Kaissling B, Biber J, Mürer H, Levi M: Action of
Parathyroid Hormones on Phosphate Transporter mRNA and Protein in Rat Renal
Proximal Tubules. J Am Soc Nephrology, 5:865, 1994.
68. Arar M, Baum M, Biber J, Mürer H, Levi M: Cellular Mechanisms of Regulation
of Na-Pi Cotransport by Epidermal Growth Factor (EGF) in OK Cells. J Am Soc
Nephrology, 5:858, 1994.
69. Loghman-Adham M, Levi M, Motock GT, Wilson P: Na+-Pi Cotransporter
(NaPi-COT) Abundance in Renal Brush Border Membranes (BBM) and Endosomes (EV).
J Am Soc Nephrology, 5:868, 1994.
70. Chervu I, Shayman JA, Scott SA, Wilson PV: Role of Glycosphingolipids (GSL)
in the Renal Hypertrophy (RH) on The Potassium Depleted (KD) Rat. J Am Soc
Nephrology, 5:690, 1994.
71. Lötscher M, Biber J, Kaissling B, Murer H, Levi M: Dexamethasone Modulates
Rat Renal Na-Pi Cotransporter mRNA and Abundance. J Investigative Med, 43:352A,
1995.
72. Sorribas V, Lötscher M. Loffing J. Biber J, Kaissling B, Murer H, Levi M:
Cellular Mechanisms of the Age-Related Decrease in Renal Phosphate Transport. J
Investigative Med, 43:352A, 1995.
73. Lötscher M, Biber J, Murer H, Kaissling B, Levi M: Role of Microtubules in
the Rapid Upregulation of Rat Renal Proximal Tubular Na-Pi Cotransport
Following Dietary Pi Restriction. J Am Soc Nephrol, 6:951, 1995.
74. Markovich D, Biber J, Murer H, Levi M: Dietary K Deficiency Impairs Rat
Renal Proximal Tubular Sulfate Transport. J Am Soc Nephrol, 6:952, 1995.
75. Arar M, Elshihabi I, Levi M: Epidermal Growth Factor Inhibits Na-Pi
Transport in Rat Brush Border Membrane Vesicles. J Am Soc Nephrol, 6:941, 1995.
76. Sorribas V, Lötscher M, Loffing J, Biber J, Kaissling B, Murer H, Levi M:
Role of Impaired NaPi-2 Expression in the Age-Related Decrease in Renal Pi
Transport. J Am Soc Nephrol, 6:955, 1995.
77. Lötscher M, Kaissling B, Kempson S, Biber J, Murer H, Levi M: Parathyroid
Hormone Induces Rapid Endocytosis of a Rat Renal Type II Na-Pi cotransporter.
Molecular Biology of the Cell, 1995.
78. Levi M, Giusti AM, Cruz CJ, Wilson P, Nguyen S, Gratton E, Sapora O,
Parasassi T: Cell Membrane Reversible "Aging" Detected by Laurdan GP
is Associated With An Increase in Cholesterol Content. Biophysical J, 70:A95,
1996.
79. Cruz CJ, Giocondi MC, Wilson P, Le Grimellec C, Levi M: The Role of
Cholesterol in Modulating Renal Brush Border Membrane Lipid Fluidity and Phase
Transitions. Biophysical J., 70:A29, 1996.
80. Sorribas V, Alcalde AI, Morales RM, Sarasa M, Biber J, Murer H, Levi M:
Gentamicin Inhibits Na/Phosphate Cotransport Activity. J. Am Soc Nephrol 7:1846
(A2999), 1996.
81. Nguyen S, Markovich D, Wilson P, Biber J, Murer H, Sakhaee K, Levi M:
Metabolic Acidosis Modulates Rat Renal Proximal Tubular Sulfate Transport
Activity. J. Am Soc Nephrol 7:1258 (A0050), 1996.
82. Wilson P, Sorribas V, Nguyen S, Lötscher M, Biber J, Murer H, Levi M: Acute
and Chronic Metabolic Acidosis Inhibits Rat Renal Na/Pi Cotransport Activity.
J. Am Soc Nephrol 7:1809 (A2814), 1996.
83. Lötscher M, Levi M, Biber J, Murer H, Kaissling B: Parathyroid Hormone
Induces Rapid Endocytosis of Renal Type II Na/Pi Cotransporter. J. Am Soc
Nephrol 783:1804 (A2787), 1996.
84. Puttaparthi K, Berry N, Mia A, Gessel M, Rogers T, Levi M: Dietary
Phosphate Modulates the Intrarenal Expression of Epidermal Growth Factor
Receptor, Molecular Biology of Cell, 1996.
85. Parasassi T, Levi M, Yu W, Gratton E: Two-photon Fluorescence Microscopy of
LAURDAN GP Domains in Biological Membranes Using Polarized Laser Excitation.
Biophysical J, 1997.
86. Kumar V, Wilson P, Parasassi T, Gratton E, Levi M: Influence of
Sphingomyelin on Lipid Dynamics as Detected by LAURDAN Fluorescence.
Biophysical J, 1997.
87. Gratton E, Levi M, Yu W, Parasassi T: Two-Photon Fluorescence Microscopy of
Laurdan GP Domains in Multilamellar Phospholipid Vesicles Using Polarized Laser
Excitation. Biophysical J, 1997.
88. Kumar V, Dev D, Levi M: Application of Near-Infrared Tissue Spectrometer
(Oxygen Sensor) For Diagnosis of Peripheral Vascular Disease in ESRD. J Am Soc
Nephrol, A0344, 1997.
89. Zajicek H, Wang H, Wiederkehr M, Levi M: Cholesterol Modulates Na+ -Pi
Cotransport in OK Cells. J Am Soc Nephrol, A2653, 1997.
90. Levi M, Gratton E, Parasassi T: Two-Photon Fluorescence Microscopy of
Laurdan GP Domains in OK Cells in Rat Renal Brush Border and Basolateral
Membranes Using Polarized Laser Excitation. J Am Soc Nephrol, A2627, 1997.
91. Wang H, Zajicek H, Lederer E, Levi M: Endogenous and Exogenous Ceramides
Regulate Na/Pi Cotransport Activity in OK Cells. J Am Soc Nephrol, A2649, 1997.
92. Wang H, Puttaparthi K, Rogers T, Zajicek H, Levi M: Dietary Potassium
Deficiency Modulates Renal Phosphate Transport and Glycosphingolipid
Composition. Molecular Biology of the Cell, 1997.
93. Alcalde AI, Sarasa M, Morales R, Aramayona U, Biber J, Murer H, Levi M,
Sorribas V: Thyroid Hormone Modulates Renal Inorganic Phosphate Reabsorption by
Enhancing the Rate of NPT-2 Gene Transcription. Molecular Biology of the Cell,
1997.
94. Zajicek H, Yu W, Wang H, Gratton E, Parasassi T, Levi M: Spatial Resolution
of the Effects of Cholesterol Deprivation and/or Enrichment on OK Cell
Membranes by LAURDAN GP Two-Photon Fluorescence Microscopy. Biophysical J,
1998.
95. Wang H, Zajicek HK, Levi M: Ceramide and Sphingosine-1-Phosphate Modulate
Na/Pi Cotransport in OK Cells. J Am Soc Nephrol, A2865, 1998.
96. Michener B, Levi M, Choudhury D: Dialysis Volume Removal May Result in
Lower Extremity Ischemia. J Am Soc Nephrol, A1329, 1998.
97. Elhalel-Dranitzki M, Rubinger D, Moscovici A, Wald H, Sorribas V, Levi M,
Popovtzer M: Reduced NaPi-2 Gene Expression in Chronic Renal Failure (CRF):
Underlying Mechanism of Tubular Phosphaturic Adaptation. J Am Soc Nephrol,
A2827, 1998.
98. Lai L-W, Wang H, Levi M, Lien YH: Down-Regulation of Renal Na/Pi-2
Cotransporter in Carbonic Anhydrase II Deficient Mice. J Am Soc Nephrol, A2844,
1998.
99. Choudhury D, Levi M, Fennelly P. Evaluation of Vascular Steal with Near
Infrared Spectroscopy. J Am Soc Nephrol, A1028, 1999
100. Halaihel N, Zajicek HK, Wilson PV, Levi M. Gentamicin Causes Rapid
Endocytoiss of Na/Pi Cotransporters in the Rat, J Am Soc Nephrol, A3085, 1999.
101. Elhalel-Dranitzki M, Rubinger D, Moscovici A, Wald H, Levi M, Popovtzer
MM. Reduced NaPi-2 Gene Expressio in Chronic Renal Failure: Role of Parathyroid
Hormone (PTH) and Dietary Phosphate (Pi). J Am Soc Nephrol, A3080, 1999.
102.
103. Woda CB, Mulroney SE, Levi M, Halaihel N, Haramati A. Nephron Sites of
Phosphate (Pi) Reabsorption in the Juvenile Rat. J Am Soc Nephrol, A3112, 1999.
104. Zajicek HK,
105. Friedlaender MM, Wald H, Elhalel-Dranitsky M, Levi M, Popovtzer MM.
Chronic Administration of 1,25 (OH)2D3 Decreases Renal NaPi2 mRNA Expression in
PTH-Infused PTX Rats. J Am Soc Nephrol, A3132, 1999.
106. Friedlaender MM, Wald H, Levi M, Popovtzer MM. IGF-1 Incrreases NaPi2 mRNA
Expression in Intact Rat Kidneys but not after Ischemic ARF. J Am Soc Nephrol,
A3273, 1999.
107. Haviv YS, Wald H, Levi M, Elhalel-Dranitzki M, Popovtzer MM. Dysfunction
of Apical Na/Pi-Cotransproters Is Not the Mechanism of Phopshaturia in Fanconi
Synddrome (FS). J Am Soc Nephrol, A3278, 1999.
108. Halaihel N, Sun L, Puttaparthi K,
109. Rubinger D, Gimelreich D, Friedlaender MM, Elhalel-Dranitzki M, Wald H,
Halaihel N, Levi M, Popovtzer MM. Renal Phosphate Trnasport During Ischemic
Reperfusion Injury (IRI) in the Kidney. J Am Soc Nephrol, A3105, 1999.
110. Raj DSC, Harrell A, Juang J, Choudhury D, Levi M, Depner T, Work J. Small
Molecular Weight Solute Clearance with High and Low Flux Dialysis. J Am Soc
Nephrol, A1347, 1999.
111. Raj DSC, Konstantinides F, San Pedro G, Vincent B, Levi M, Simpson K, Sato
E, Jones KL, Welbourne TC, Work J, Robbins RA. Does Nitric Oxide Mediate
Dialysis Induced Hypotension. J Am Soc Nephrol, A1517, 1999.
112. Halaihel N, Sun L, Zajicek H, Puttaparthi K, Zhou Y-T, Wilson P,
113. Sun L, Levi M. Free Fatty Acids Induce Cell Proliferation and Inhibition
of TGF-( Expression in Cultured Mesangial Cells. Diabetes, 2000.
114. Halaihel N, Zajicek H, Sun L, Wilson P, Zhou Y-T, Levi M. Troglitazone
Modulates Type II Renal Na/Pi Cotransport Protein in Zucker Diabetic Fatty
Rats. Diabetes, 2000
115. Raj DSC, Jain SK, Lim G, Sheeba SD, Hsiao G, Choudhury D, Levi M,
Welbourne TC. Influence of renal replacement therapies on oxidant stress. Am
Soc Nephrol , 2000.
116. Elhalel-Dranitzki M, Wald H, Rubinger D, Gal-Moscovici A, Levi M,
Popovtzer MM. Regulation of NaPi-2 mRNA and Transporter Protein in Chronic
Renal Failure: Role of Parathyroid Hormone (PTH) and Dietary Phosphate (Pi). Am
Soc Nephrol, 2000
117. Haviv YS, Wald H, Levi M, Dranitzki-Elhalel M, Popovtzer MM. Late-Onset
Down-Regulation of NaPi-2 in Experimental Fanconi’s Syndrome. Am Soc Nephrol,
2000.
118. Choudhury D, Ahmed Z, Ranganna K, Choudhury A, Levi M. ACE-Inhibitors
Prolong PTFE Graft Survival in Hemodialysis Patients. Am Soc Nephrol, 2000.
119. Sun L, Halaihel N, Levi M. Free Fatty Acids Regulate Mesangial Cell
Proliferation by Activating p42/44 MAP Kinase. Am Soc Nephrol, 2000.
120. Halaihel N, Sun L, Zajicek H, Wilson P, Levi M. Role of Obesity and
Lipotoxicity in Diabetic Nephropathy in ZDF Rats. Am Soc Nephrol, 2000.
121. Zajicek HK, Wilson P, Halaihel N, Levi M. Acute Upregulation of NaPi-2 in
Proximal Tubular BBM is Associated with Increased Excretion of NaPi-2 in the
Urine. Am Soc Nephrol, 2000.
122. Halaihel N, Loui B, DeJesus M, Haramati A, Levi M, Mulroney SE. Rapid
Internalization of Brain and kidney NaPi-2 Transporters After Central Injection
of Phosphate (Pi). Am Soc Nephrol, 2000
123. Cheng M, Bagatolli L, Zajicek H, Halaihel N, Levi M, Gratton E, Mantulin
W. Characterization of giant unilamellar vesicles of integral membrane extracts
from rat kidney brushborder and basolateral membranes using two photon
fluorescence microscopy. Biophys Society, 2001.
124. Sun L, Zhang W, Halaihel N, Zajicek HK, Rogers T, Levi M. Role of sterol
regulatory element binding protein in diabetic nephropathy. J Am Soc Nephrol
12:A3047, 2001.
125. Backenroth R, Parnas M, Wald H, Popovtzer MM, Levi M. Mutant opossum
kidney cells (OK) with spontaneously elevated cAMP Levels. Evidence for a key
role of cAMP in modulating Na coupled pathway. J Am Soc Nephrol 12:A3912, 2001.
126. Zajicek HK, Halaihel N, Zhang W, Sun L, Levi. Dynamic assocation of Na/Pi
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