Graduate Student
Program in Cell and Developmental Biology
MS Room #3803. Campus Box C-240. Tel (303) 315-8145. Fax (303) 315-8110.
Email Jenifer.Monks@UCHSC.edu

| Education | Employment & Experience | Publications & Presentations | Professional Societies | Research Interests |

• Bachelor of Science in General Chemistry, Harvey Mudd College, 1991
  
• Currently working on Doctorate in Cell and Developmental Biology, University of Colorado Denver
  

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• June 1994-present, Graduate Assistanship, Dr. Margaret Neville, University of Colorado Denver. Dissertation Research. Developed in vivo techniques to study transport of extra-alveolar proteins by the mammary epithelial cells in the lactating mouse mammary gland. Utilizing these techniques, dissected the transport pathways for transcytosed substances, recycled materials, and secreted components of mouse milk, characterizing sorting mechanisms and organelles involved. Discovered a possible fluid-phase component of transcytosed materials.
  
• June 1992-December 1993, Graduate Assistantship, Dr. Claude Selitrennikoff, University of Colorado Denver, Graduate Research. Purified zeamatin, an antifungal protein, from corn seed. Tested its antifungal activity against various strains of fungi. Began elucidating zeamatin's mechanism of action against these fungi.
  
• January 1991-August 1991, Senior Research and Summer Research Assistantship, Dr. David Sadava, Joint Sciences Center, Harvey Mudd College. Studied the effects of a Vitamin E deficient diet on the intestinal growth and morphology of mice using 3H-thymidine incorporation, autoradiography and microscopy.
  
• June-August 1990, Summer Research Assistantship, Dr. Philip Myhre, Harvey Mudd College. Furthered the synthetic protocol of 13C-labeled compounds for solid-state NMR analysis of carbon-carbon bonding in reaction intermediates.
  

CONTENTS

• 1. Monks, J. and M.C. Neville. 1995. LPL Transport in the Lactating Mammary Gland. Gordon Research Conference on Mammary Gland Biology. New London, NH.
  
• 2. Monks, J., Gavigan, S., and M.C. Neville. 1996. LDL is transported whole, as is Albumin, across the Lactating Mammary Epithelium. Gordon Research Conference on Lipid Metabolism. Meriden, NH.
  
• 3. Monks, J. and M.C. Neville. 1997. Transport of Extra-Alveolar Proteins into Mouse Milk. Gordon Research Conference on Mammary Gland Biology. Plymouth, NH.
  
• 4. Zhang, P., Sawicki, V., Lewis, A., Hanson, L., Monks, J., Nuijens, J.H., and M.C. Neville. 1997. Iron transfer from plasma to mouse milk: insight from effect of low iron diet. International Symposium: Iron in Biology and Medicine. Saint-Malo, France
  
• 5. Neville, M.C., Chatfield, K., Hanson, L., Lewis, A., Monks, J., Nuijens, J., Ollivier-Bousquet, M., Schanbacher, F., Sawicki, V., Zhang, P. Lactoferrin secretion into mouse milk: development of secretory activity, the localization of lactoferrin in the secretory pathway and interactions of lactoferrin with milk iron. in Lactoferrin: Structure and Function. Adv. Exp. Med. Biol. In Press.
  
• 6. Zhang, P., Sawicki, V., Lewis, A., Hanson, L., Monks, J. and Neville, M.C. 1998. The Effect of Low Iron Diets on Iron Secretion into Mouse Milk. Submitted to J. Nutr.
  
• 7. Monks, J. and M.C. Neville. Vesicular Transport of Soluble Substances into Mouse Milk. Proceedings of International Society for Research in Human Milk and Lactation. (in press)
  
• 8. Monks, J. and M.C. Neville. April 1998. Elucidating Albumin Transcytosis across the Mammary Epithelium of the Lactating Mouse. Intracellular Transports in Mammary Epithelial Cells, COST conference, INRA, Jouy-en-Josas, France.
  
• 9. Neville, M.C., Madina, D., Monks, J. and R.C. Hovey. 1998. The Mammary Fat Pad. J. Mamm. Gland Biol. and Neoplasia. 3(2):109-116.
  
• 10. Monks, J., Hanson, L., Uelman-Huey, P., Eckel, R., Neville, M.C. and S. Gavigan. Low density lipoprotein remnants are transferred across the mammary epithelium into the milk of lactating mice. (in preparation)
  
• 11. Monks, J., Lewis, A. and M.C. Neville. Albumin Transport into Mouse Milk is via Transcytosis across the Mammary Epithelium. (in preparation)
  

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• Association for Women in Science
  
• The American Society for Cell Biology
  

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I am interested in continuing my studies of the lactating mammary gland. I would like to use the skills I acquired in Dr. Neville's laboratory to gain a deeper understanding of the cell biology of the mammary epithelial cell in vivo.

Main areas of research interest include:

• 1) continuing to study the secretory/transport mechanisms of this cell,
• 2) cell-cell interactions and/or functioning of the stromal cells,
• 3) transport into milk of substances important to the developing immune system of the neonate,
• 4) apoptosis in involution.
  

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