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Department of Psychiatry
Schizophrenia Research Center Publications
Mexal S, Berger R, Adams CE, Ross RG, Freedman R, Leonard S, Brain pH has a significant impact on human postmortem hippocampal gene expression profiles. Brain Research. Jul 2006 [Epub ahead of print] PubMed ID: 16843448
Leonard S, Freedman R, Genetics of chromosome 15q13-q14 in schizophrenia. Biological psychiatry. 60:115-22, Jul 2006 PubMed ID: 16843094
Hall MH, Schulze K, Rijsdijk F, Picchioni M, Ettinger U, Bramon E, Freedman R, Murray RM, Sham P, Heritability and Reliability of P300, P50 and Duration Mismatch Negativity. Behaior Genetics. Jul 2006 [Epub ahead of print] PubMed ID: 16826459
Ross RG, Psychotic and manic-like symptoms during stimulant treatment of attention deficit hyperactivity disorder. The American journal of psychiatry. 163:1149-52, Jul 2006 PubMed ID: 16816217
Olincy A, Harris JG, Johnson LL, Pender V, Kongs S, Allensworth D, Ellis J, Zerbe GO, Leonard S, Stevens KE, Stevens JO, Martin L, Adler LE, Soti F, Kem WR, Freedman R, Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Archives of general psychiatry. 63:630-8, Jun 2006 PubMed ID: 16754836
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reedman R, Leonard S, Waldo M, Gault J, Olincy A, Adler LE, Characterization of allelic variants at chromosome 15q14 in schizophrenia. Genes, brain, and behavior. 5 Suppl 1:14-22, 2006 PubMed ID: 16417613
Yao JK, Leonard S, Reddy R, Altered glutathione redox state in schizophrenia. Disease markers. 22:83-93, 2006 PubMed ID: 16410648
Lewis DA, Michels R, Pine DS, Schultz SK, Tamminga CA, Freedman R, Conflict of interest. The American journal of psychiatry. 163:571-3, Apr 2006 PubMed ID: 16585427
Tanabe J, Tregellas JR, Martin LF, Freedman R, Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia. Biological psychiatry. 59:754-61, Apr 2006 PubMed ID: 16259965
Tregellas JR, Davalos DB, Rojas DC, Effect of task difficulty on the functional anatomy of temporal processing. Neuroimage. 32:307-15, Aug 2006 PubMed ID: 16624580
Gabbard GO, Freedman R, Psychotherapy in the Journal: what's missing? The American journal of psychiatry. 163:182-4, Feb 2006 PubMed ID: 16449467
Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, Rice JP, Cox NJ, Martinez M, Mowry BJ, Amin F, Silverman JM, Black DW, Byerley WF, Crowe RR, Freedman R, Cloninger CR, Levinson DF, Gejman PV, Genomewide Linkage Scan of 409 European-Ancestry and African American Families with Schizophrenia: Suggestive Evidence of Linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the Combined Sample. American journal of human genetics. 78:315-33, Feb 2006 PubMed ID: 16400611
Freedman R, Nancy C. Andreasen, M.D., Ph.D.: editor emeritus perfectus. The American journal of psychiatry. 163:3-4, Jan 2006 PubMed ID: 16390878
Swerdlow NR, Geyer MA, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP, Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 31:506-15, Mar 2006 PubMed ID: 16123772
Davalos DB, Kisley MA, Freedman R, Behavioral and electrophysiological indices of temporal processing dysfunction in schizophrenia. The Journal of neuropsychiatry and clinical neurosciences. 17:517-25, 2005 PubMed ID: 16387992
Freedman R, Ross R, Leonard S, Myles-Worsley M, Adams CE, Waldo M, Tregellas J, Martin L, Olincy A, Tanabe J, Kisley MA, Hunter S, Stevens KE, Early biomarkers of psychosis. Dialogues in clinical neuroscience. 7:17-29, 2005 PubMed ID: 16060593
Peng JH, Fryer JD, Hurst RS, Schroeder KM, George AA, Morrissy S, Groppi VE, Leonard SS, Lukas RJ, High-affinity epibatidine binding of functional, human alpha7-nicotinic acetylcholine receptors stably and heterologously expressed de novo in human SH-EP1 cells. The Journal of pharmacology and experimental therapeutics. 313:24-35, Apr 2005 PubMed ID: 15590768
Ross RG, Heinlein S, Zerbe GO, Radant A, Saccadic eye movement task identifies cognitive deficits in children with schizophrenia, but not in unaffected child relatives. Journal of child psychology and psychiatry, and allied disciplines. 46:1354-62, Dec 2005 PubMed ID: 16313436
Tregellas JR, Tanabe JL, Martin LF, Freedman R, FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia. The American journal of psychiatry. 162:391-3, Feb 2005 PubMed ID: 15677609
Adler LE, Cawthra EM, Donovan KA, Harris JG, Nagamoto HT, Olincy A, Waldo MC, Improved p50 auditory gating with ondansetron in medicated schizophrenia patients. The American journal of psychiatry. 162:386-8, Feb 2005 PubMed ID: 15677607
Olincy A, Martin L, Diminished suppression of the P50 auditory evoked potential in bipolar disorder subjects with a history of psychosis. The American journal of psychiatry. 162:43-9, Jan 2005 PubMed ID: 15625200
Koike K, Hashimoto K, Takai N, Shimizu E, Komatsu N, Watanabe H, Nakazato M, Okamura N, Stevens KE, Freedman R, Iyo M, Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophrenia research. 76:67-72, Jul 2005 PubMed ID: 15927799
Hanlon FM, Miller GA, Thoma RJ, Irwin J, Jones A, Moses SN, Huang M, Weisend MP, Paulson KM, Edgar JC, Adler LE, Cañive JM, Distinct M50 and M100 auditory gating deficits in schizophrenia. Psychophysiology. 42:417-27, Jul 2005 PubMed ID: 16008770
Thoma RJ, Hanlon FM, Moses SN, Ricker D, Huang M, Edgar C, Irwin J, Torres F, Weisend MP, Adler LE, Miller GA, Canive JM, M50 sensory gating predicts negative symptoms in schizophrenia. Schizophrenia research. 73:311-8, Mar 2005 PubMed ID: 15653276
Wu PH, Poelchen W, Proctor WR, Differential GABAB Receptor Modulation of Ethanol Effects on GABA(A) synaptic activity in hippocampal CA1 neurons. The Journal of pharmacology and experimental therapeutics. 312:1082-9, Mar 2005 PubMed ID: 15615867
Edgar JC, Miller GA, Moses SN, Thoma RJ, Huang MX, Hanlon FM, Weisend MP, Sherwood A, Bustillo J, Adler LE, Cañive JM, Cross-modal generality of the gating deficit. Psychophysiology. 42:318-27, May 2005 PubMed ID: 15943686
Hashimoto K, Iyo M, Freedman R, Stevens KE, Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors. Psychopharmacology. 183:13-9, Nov 2005 PubMed ID: 16136299
Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S, Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Brain research. Molecular brain research. 139:317-32, Oct 2005 PubMed ID: 16122832
Freedman R, The choice of antipsychotic drugs for schizophrenia. The New England journal of medicine. 353:1286-8, Sep 2005 PubMed ID: 16172204
Du YP, Saranathan M, Foo TK, An accurate, robust, and computationally efficient navigator algorithm for measuring diaphragm positions. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. 6:483-90, 2004 PubMed ID: 15137332
Yao JK, Leonard S, Reddy RD, Increased nitric oxide radicals in postmortem brain from patients with schizophrenia. Schizophrenia bulletin. 30:923-34, 2004 PubMed ID: 15954198
Davalos DB, Compagnon N, Heinlein S, Ross RG, Neuropsychological deficits in children associated with increased familial risk for schizophrenia. Schizophrenia research. 67:123-30, Apr 2004 PubMed ID: 14984871
Myles-Worsley M, Ord L, Blailes F, Ngiralmau H, Freedman R, P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia. Biological psychiatry. 55:663-7, Apr 2004 PubMed ID: 15038993
Tregellas JR, Tanabe JL, Miller DE, Ross RG, Olincy A, Freedman R, Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study. The American journal of psychiatry. 161:315-21, Feb 2004 PubMed ID: 14754781
Harris JG, Kongs S, Allensworth D, Martin L, Tregellas J, Sullivan B, Zerbe G, Freedman R, Effects of nicotine on cognitive deficits in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 29:1378-85, Jul 2004 PubMed ID: 15138435
Martin LF, Kem WR, Freedman R, Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology. 174:54-64, Jun 2004 PubMed ID: 15205879
Prochazka AV, Kick S, Steinbrunn C, Miyoshi T, Fryer GE, A randomized trial of nortriptyline combined with transdermal nicotine for smoking cessation. Archives of internal medicine. 164:2229-33, Nov 2004 PubMed ID: 15534159
Adler LE, Olincy A, Cawthra EM, McRae KA, Harris JG, Nagamoto HT, Waldo MC, Hall MH, Bowles A, Woodward L, Ross RG, Freedman R, Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. The American journal of psychiatry. 161:1822-8, Oct 2004 PubMed ID: 15465979
Miklowitz DJ, George EL, Axelson DA, Kim EY, Birmaher B, Schneck C, Beresford C, Craighead WE, Brent DA, Family-focused treatment for adolescents with bipolar disorder. Journal of affective disorders. 82 Suppl 1:S113-28, Oct 2004 PubMed ID: 15571785
Proctor WR, Wu PH, Bennett B, Johnson TE, Differential effects of ethanol on gamma-aminobutyric acid-A receptor-mediated synaptic currents in congenic strains of inbred long and short-sleep mice. Alcoholism, clinical and experimental research. 28:1277-83, Sep 2004 PubMed ID: 15365296
Ross RG, Novins D, Farley GK, Adler LE, A 1-year open-label trial of olanzapine in school-age children with schizophrenia. Journal of child and adolescent psychopharmacology. 13:301-9, 2003 PubMed ID: 14642018
Ross RG, Schaeffer J, Compagnon N, Heinlein S, Beresford C, Farley G, Creating school-age versions of semistructured interviews for the prodrome to schizophrenia: lessons from case reviews. Schizophrenia bulletin. 29:729-35, 2003 PubMed ID: 14989410
Freedman R, Electrophysiological phenotypes. Methods in molecular medicine. 77:215-25, 2003 PubMed ID: 12298371
Kisley MA, Polk SD, Ross RG, Levisohn PM, Freedman R, Early postnatal development of sensory gating. Neuroreport. 14:693-7, Apr 2003 PubMed ID: 12692465
Ross RG, Early expression of a pathophysiological feature of schizophrenia: saccadic intrusions into smooth-pursuit eye movements in school-age children vulnerable to schizophrenia. Journal of the American Academy of Child and Adolescent Psychiatry. 42:468-76, Apr 2003 PubMed ID: 12649634
Moxon KA, Gerhardt GA, Adler LE, Dopaminergic modulation of the P50 auditory-evoked potential in a computer model of the CA3 region of the hippocampus: its relationship to sensory gating in schizophrenia. Biological cybernetics. 88:265-75, Apr 2003 PubMed ID: 12690485
Moxon KA, Gerhardt GA, Gulinello M, Adler LE, Inhibitory control of sensory gating in a computer model of the CA3 region of the hippocampus. Biological cybernetics. 88:247-64, Apr 2003 PubMed ID: 12690484
Proctor WR, Poelchen W, Bowers BJ, Wehner JM, Messing RO, Dunwiddie TV, Ethanol differentially enhances hippocampal GABA A receptor-mediated responses in protein kinase C gamma (PKC gamma) and PKC epsilon null mice. The Journal of pharmacology and experimental therapeutics. 305:264-70, Apr 2003 PubMed ID: 12649378
Du YP, Prospective navigator gating with a dual acceptance window technique to reduce respiratory motion artifacts in 3D MR coronary angiography. The international journal of cardiovascular imaging. 19:157-62, Apr 2003 PubMed ID: 12749397
Davalos DB, Kisley MA, Ross RG, Effects of interval duration on temporal processing in schizophrenia. Brain and cognition. 52:295-301, Aug 2003 PubMed ID: 12907174
Edgar JC, Huang MX, Weisend MP, Sherwood A, Miller GA, Adler LE, Cañive JM, Interpreting abnormality: an EEG and MEG study of P50 and the auditory paired-stimulus paradigm. Biological psychology. 65:1-20, Dec 2003 PubMed ID: 14638286
Simosky JK, Stevens KE, Adler LE, Freedman R, Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism. Psychopharmacology. 165:386-96, Feb 2003 PubMed ID: 12459928
Leonard S, Freedman R, Recombination in a schizophrenic proband fails to exclude CHRNA7 at chromosome 15q14. Molecular psychiatry. 8:145-6, Feb 2003 PubMed ID: 12610645
Kisley MA, Olincy A, Robbins E, Polk SD, Adler LE, Waldo MC, Freedman R, Sensory gating impairment associated with schizophrenia persists into REM sleep. Psychophysiology. 40:29-38, Jan 2003 PubMed ID: 12751801
Davalos DB, Kisley MA, Polk SD, Ross RG, Mismatch negativity in detection of interval duration deviation in schizophrenia. Neuroreport. 14:1283-6, Jul 2003 PubMed ID: 12824776
Adams CE, Comparison of alpha7 nicotinic acetylcholine receptor development in the hippocampal formation of C3H and DBA/2 mice. Brain research. Developmental brain research. 143:137-49, Jul 2003 PubMed ID: 12855185
Freedman R, Olincy A, Ross RG, Waldo MC, Stevens KE, Adler LE, Leonard S, The genetics of sensory gating deficits in schizophrenia. Current psychiatry reports. 5:155-61, Jun 2003 PubMed ID: 12685995
Olincy A, Johnson LL, Ross RG, Differential effects of cigarette smoking on performance of a smooth pursuit and a saccadic eye movement task in schizophrenia. Psychiatry research. 117:223-36, Mar 2003 PubMed ID: 12686365
Huang MX, Edgar JC, Thoma RJ, Hanlon FM, Moses SN, Lee RR, Paulson KM, Weisend MP, Irwin JG, Bustillo JR, Adler LE, Miller GA, Canive JM, Predicting EEG responses using MEG sources in superior temporal gyrus reveals source asynchrony in patients with schizophrenia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 114:835-50, May 2003 PubMed ID: 12738429
Gault J, Hopkins J, Berger R, Drebing C, Logel J, Walton C, Short M, Vianzon R, Olincy A, Ross RG, Adler LE, Freedman R, Leonard S, Comparison of polymorphisms in the alpha7 nicotinic receptor gene and its partial duplication in schizophrenic and control subjects. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 123:39-49, Nov 2003 PubMed ID: 14582144
Freedman R, Schizophrenia. The New England journal of medicine. 349:1738-49, Oct 2003 PubMed ID: 14585943
O'Neill HC, Schmitt MP, Stevens KE, Lithium alters measures of auditory gating in two strains of mice. Biological psychiatry. 54:847-53, Oct 2003 PubMed ID: 14550685
O'Neill HC, Rieger K, Kem WR, Stevens KE, DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats. Psychopharmacology. 169:332-9, Sep 2003 PubMed ID: 12759805
Thoma RJ, Hanlon FM, Moses SN, Edgar JC, Huang M, Weisend MP, Irwin J, Sherwood A, Paulson K, Bustillo J, Adler LE, Miller GA, Cañive JM, Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia. The American journal of psychiatry. 160:1595-605, Sep 2003 PubMed ID: 12944333
Tanabe J, Miller D, Tregellas J, Freedman R, Meyer FG, Comparison of detrending methods for optimal fMRI preprocessing. NeuroImage. 15:902-7, Apr 2002 PubMed ID: 11906230
Simosky JK, Stevens KE, Freedman R, Nicotinic agonists and psychosis. Current drug targets. CNS and neurological disorders. 1:149-62, Apr 2002 PubMed ID: 12769624
Leonard S, Gault J, Hopkins J, Logel J, Vianzon R, Short M, Drebing C, Berger R, Venn D, Sirota P, Zerbe G, Olincy A, Ross RG, Adler LE, Freedman R, Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Archives of general psychiatry. 59:1085-96, Dec 2002 PubMed ID: 12470124
Koczat DL, Rogers SJ, Pennington BF, Ross RG, Eye movement abnormality suggestive of a spatial working memory deficit is present in parents of autistic probands. Journal of autism and developmental disorders. 32:513-8, Dec 2002 PubMed ID: 12553588
Adams CE, Broide RS, Chen Y, Winzer-Serhan UH, Henderson TA, Leslie FM, Freedman R, Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation. Brain research. Developmental brain research. 139:175-87, Dec 2002 PubMed ID: 12480132
Tregellas JR, Tanabe JL, Miller DE, Freedman R, Monitoring eye movements during fMRI tasks with echo planar images. Human brain mapping. 17:237-43, Dec 2002 PubMed ID: 12395391
Freedman R, Long-term effects of early genetic influences on behavior. The New England journal of medicine. 347:213-5, Jul 2002 PubMed ID: 12124413
Freedman R, Adler LE, Olincy A, Waldo MC, Ross RG, Stevens KE, Leonard S, Input dysfunction, schizotypy, and genetic models of schizophrenia. Schizophrenia research. 54:25-32, Mar 2002 PubMed ID: 11853975
Schaeffer JL, Ross RG, Childhood-onset schizophrenia: premorbid and prodromal diagnostic and treatment histories. Journal of the American Academy of Child and Adolescent Psychiatry. 41:538-45, May 2002 PubMed ID: 12014786
Harris JG, Young DA, Rojas DC, Cajade-Law A, Scherzinger A, Nawroz S, Adler LE, Cullum CM, Simon J, Freedman R, Increased hippocampal volume in schizophrenics' parents with ancestral history of schizophrenia. Schizophrenia research. 55:11-7, May 2002 PubMed ID: 11955959
Davalos DB, Kisley MA, Ross RG, Deficits in auditory and visual temporal perception in schizophrenia. Cognitive neuropsychiatry. 7:273-82, Nov 2002 PubMed ID: 16571542
Tanabe J, Tregellas J, Miller D, Ross RG, Freedman R, Brain activation during smooth-pursuit eye movements. NeuroImage. 17:1315-24, Nov 2002 PubMed ID: 12414271
Ross RG, Olincy A, Mikulich SK, Radant AD, Harris JG, Waldo M, Compagnon N, Heinlein S, Leonard S, Zerbe GO, Adler L, Freedman R, Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypes. Psychophysiology. 39:809-19, Nov 2002 PubMed ID: 12462508
Sabeti J, Adams CE, Burmeister J, Gerhardt GA, Zahniser NR, Kinetic analysis of striatal clearance of exogenous dopamine recorded by chronoamperometry in freely-moving rats. Journal of neuroscience methods. 121:41-52, Nov 2002 PubMed ID: 12393160
Du YP, Joe Zhou X, Bernstein MA, Correction of concomitant magnetic field-induced image artifacts in nonaxial echo-planar imaging. Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 48:509-15, Sep 2002 PubMed ID: 12210916
Arciniegas DB, Topkoff JL, Rojas DC, Sheeder J, Teale P, Young DA, Sandberg E, Reite ML, Adler LE, Reduced hippocampal volume in association with p50 nonsuppression following traumatic brain injury. The Journal of neuropsychiatry and clinical neurosciences. 13:213-21, 2001 PubMed ID: 11449028
de Bruin NM, Ellenbroek BA, van Luijtelaar EL, Cools AR, Stevens KE, Hippocampal and cortical sensory gating in rats: effects of quinpirole microinjections in nucleus accumbens core and shell. Neuroscience. 105:169-80, 2001 PubMed ID: 11483310
Stevens KE, Bullock AE, Collins AC, Chronic corticosterone treatment alters sensory gating in C3H mice. Pharmacology, biochemistry, and behavior. 69:359-66, Aug 2001 PubMed ID: 11509192
Leonard S, Bertrand D, Neuronal nicotinic receptors: from structure to function. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 3:203-23, Aug 2001 PubMed ID: 11506765
Stevens KE, Bullock AE, Collins AC, Chronic corticosterone treatment alters sensory gating in C3H mice. Pharmacology, biochemistry, and behavior. 69:359-66, Aug 2001 PubMed ID: 11509192
Leonard S, Adler LE, Benhammou K, Berger R, Breese CR, Drebing C, Gault J, Lee MJ, Logel J, Olincy A, Ross RG, Stevens K, Sullivan B, Vianzon R, Virnich DE, Waldo M, Walton K, Freedman R, Smoking and mental illness. Pharmacology, biochemistry, and behavior. 70:561-70, Dec 2001 PubMed ID: 11796154
Freedman R, Leonard S, Olincy A, Kaufmann CA, Malaspina D, Cloninger CR, Svrakic D, Faraone SV, Tsuang MT, Evidence for the multigenic inheritance of schizophrenia. American journal of medical genetics. 105:794-800, Dec 2001 PubMed ID: 11803533
Adams CE, Stitzel JA, Collins AC, Freedman R, Alpha7-nicotinic receptor expression and the anatomical organization of hippocampal interneurons. Brain research. 922:180-90, Dec 2001 PubMed ID: 11743948
Freedman R, Leonard S, Genetic linkage to schizophrenia at chromosome 15q14. American journal of medical genetics. 105:655-7, Dec 2001 PubMed ID: 11803510
Freedman R, Leonard S, Gault JM, Hopkins J, Cloninger CR, Kaufmann CA, Tsuang MT, Farone SV, Malaspina D, Svrakic DM, Sanders A, Gejman P, Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7). American journal of medical genetics. 105:20-2, Jan 2001 PubMed ID: 11424985
Lee MJ, Breese CR, Strook ML, Leonard S, The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain. Brain research. Molecular brain research. 86:115-24, Jan 2001 PubMed ID: 11165378
Kisley MA, Olincy A, Freedman R, The effect of state on sensory gating: comparison of waking, REM and non-REM sleep. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 112:1154-65, Jul 2001 PubMed ID: 11516727
Adler LE, Olincy A, Cawthra E, Hoffer M, Nagamoto HT, Amass L, Freedman R, Reversal of diminished inhibitory sensory gating in cocaine addicts by a nicotinic cholinergic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 24:671-9, Jun 2001 PubMed ID: 11331147
Ross RG, Olincy A, Zerbe G, Radant A, Which duration of postsaccadic slowing identifies anticipatory saccades during smooth pursuit eye movements? Psychophysiology. 38:325-33, Mar 2001 PubMed ID: 11347877
Ross RG, Compagnon N, Diagnosis and treatment of psychiatric disorders in children with a schizophrenic parent. Schizophrenia research. 50:121-9, May 2001 PubMed ID: 11378320
Simosky JK, Stevens KE, Kem WR, Freedman R, Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biological psychiatry. 50:493-500, Oct 2001 PubMed ID: 11600102
Simosky JK, Stevens KE, Kem WR, Freedman R, Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biological psychiatry. 50:493-500, Oct 2001 PubMed ID: 11600102
Harris JG, Filley CM, CADASIL: neuropsychological findings in three generations of an affected family. Journal of the International Neuropsychological Society : JINS. 7:768-74, Sep 2001 PubMed ID: 11575598
Freedman R, Adams CE, Adler LE, Bickford PC, Gault J, Harris JG, Nagamoto HT, Olincy A, Ross RG, Stevens KE, Waldo M, Leonard S, Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia. American journal of medical genetics. 97:58-64, 2000 PubMed ID: 10813805
Arciniegas D, Olincy A, Topkoff J, McRae K, Cawthra E, Filley CM, Reite M, Adler LE, Impaired auditory gating and P50 nonsuppression following traumatic brain injury. The Journal of neuropsychiatry and clinical neurosciences. 12:77-85, 2000 PubMed ID: 10678517
Ross RG, Olincy A, Harris JG, Sullivan B, Radant A, Smooth pursuit eye movements in schizophrenia and attentional dysfunction: adults with schizophrenia, ADHD, and a normal comparison group. Biological psychiatry. 48:197-203, Aug 2000 PubMed ID: 10924662
Weiland S, Bertrand D, Leonard S, Neuronal nicotinic acetylcholine receptors: from the gene to the disease. Behavioural brain research. 113:43-56, Aug 2000 PubMed ID: 10942031
Buervenich S, Carmine A, Arvidsson M, Xiang F, Zhang Z, Sydow O, Jönsson EG, Sedvall GC, Leonard S, Ross RG, Freedman R, Chowdari KV, Nimgaonkar VL, Perlmann T, Anvret M, Olson L, NURR1 mutations in cases of schizophrenia and manic-depressive disorder. American journal of medical genetics. 96:808-13, Dec 2000 PubMed ID: 11121187
Freedman R, Adams CE, Leonard S, The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. Journal of chemical neuroanatomy. 20:299-306, Dec 2000 PubMed ID: 11207427
Waldo MC, Adler LE, Leonard S, Olincy A, Ross RG, Harris JG, Freedman R, Familial transmission of risk factors in the first-degree relatives of schizophrenic people. Biological psychiatry. 47:231-9, Feb 2000 PubMed ID: 10682220
Ross RG, Harris JG, Olincy A, Radant A, Eye movement task measures inhibition and spatial working memory in adults with schizophrenia, ADHD, and a normal comparison group. Psychiatry research. 95:35-42, Jul 2000 PubMed ID: 10904121
Olincy A, Ross RG, Harris JG, Young DA, McAndrews MA, Cawthra E, McRae KA, Sullivan B, Adler LE, Freedman R, The P50 auditory event-evoked potential in adult attention-deficit disorder: comparison with schizophrenia. Biological psychiatry. 47:969-77, Jun 2000 PubMed ID: 10838065
Leonard S, Breese C, Adams C, Benhammou K, Gault J, Stevens K, Lee M, Adler L, Olincy A, Ross R, Freedman R, Smoking and schizophrenia: abnormal nicotinic receptor expression. European journal of pharmacology. 393:237-42, Mar 2000 PubMed ID: 10771019
Yao JK, Leonard S, Reddy RD, Membrane phospholipid abnormalities in postmortem brains from schizophrenic patients. Schizophrenia research. 42:7-17, Mar 2000 PubMed ID: 10706981
Poelchen W, Proctor WR, Dunwiddie TV, The in vitro ethanol sensitivity of hippocampal synaptic gamma-aminobutyric acid(A) responses differs in lines of mice and rats genetically selected for behavioral sensitivity or insensitivity to ethanol. The Journal of pharmacology and experimental therapeutics. 295:741-6, Nov 2000 PubMed ID: 11046113
Breese CR, Lee MJ, Adams CE, Sullivan B, Logel J, Gillen KM, Marks MJ, Collins AC, Leonard S, Abnormal regulation of high affinity nicotinic receptors in subjects with schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 23:351-64, Oct 2000 PubMed ID: 10989262
Benhammou K, Lee M, Strook M, Sullivan B, Logel J, Raschen K, Gotti C, Leonard S, [(3)H]Nicotine binding in peripheral blood cells of smokers is correlated with the number of cigarettes smoked per day. Neuropharmacology. 39:2818-29, Oct 2000 PubMed ID: 11044752
Adams CE, Stevens KE, Kem WR, Freedman R, Inhibition of nitric oxide synthase prevents alpha 7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus. Brain research. 877:235-44, Sep 2000 PubMed ID: 10986337
Nagamoto HT, Adler LE, McRae KA, Huettl P, Cawthra E, Gerhardt G, Hea R, Griffith J, Auditory P50 in schizophrenics on clozapine: improved gating parallels clinical improvement and changes in plasma 3-methoxy-4-hydroxyphenylglycol. Neuropsychobiology. 39:10-7, 1999 PubMed ID: 9892854
Ross RG, Olincy A, Harris JG, Radant A, Hawkins M, Adler LE, Freedman R, Evidence for bilineal inheritance of physiological indicators of risk in childhood-onset schizophrenia. American journal of medical genetics. 88:188-99, Apr 1999 PubMed ID: 10206241
Moxon KA, Gerhardt GA, Bickford PC, Austin K, Rose GM, Woodward DJ, Adler LE, Multiple single units and population responses during inhibitory gating of hippocampal auditory response in freely-moving rats. Brain research. 825:75-85, Apr 1999 PubMed ID: 10216175
Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Compagnon N, Freedman R, The effects of age on a smooth pursuit tracking task in adults with schizophrenia and normal subjects. Biological psychiatry. 46:383-91, Aug 1999 PubMed ID: 10435204
Waldo MC, Freedman R, Neurobiological abnormalities in the relatives of schizophrenics. Journal of psychiatric research. 33:491-5, Dec 1999 PubMed ID: 10628524
Waldo MC, Freedman R, Neurobiological abnormalities in the relatives of schizophrenics. Journal of psychiatric research. 33:491-5, Dec 1999 PubMed ID: 10628524
Olincy A, Leonard S, Young DA, Sullivan B, Freedman R, Decreased bombesin peptide response to cigarette smoking in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 20:52-9, Jan 1999 PubMed ID: 9885785
Svoboda KR, Adams CE, Lupica CR, Opioid receptor subtype expression defines morphologically distinct classes of hippocampal interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19:85-95, Jan 1999 PubMed ID: 9870941
Waldo MC, Schizophrenia in Kosrae, Micronesia: prevalence, gender ratios, and clinical symptomatology. Schizophrenia research. 35:175-81, Jan 1999 PubMed ID: 9988854
Adler LE, Freedman R, Ross RG, Olincy A, Waldo MC, Elementary phenotypes in the neurobiological and genetic study of schizophrenia. Biological psychiatry. 46:8-18, Jul 1999 PubMed ID: 10394470
Ross RG, Olincy A, Radant A, Amplitude criteria and anticipatory saccades during smooth pursuit eye movements in schizophrenia. Psychophysiology. 36:464-8, Jul 1999 PubMed ID: 10432795
Freedman R, Adler LE, Leonard S, Alternative phenotypes for the complex genetics of schizophrenia. Biological psychiatry. 45:551-8, Mar 1999 PubMed ID: 10088045
Stevens KE, Kem WR, Freedman R, Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice. Biological psychiatry. 46:1443-50, Nov 1999 PubMed ID: 10578459
Waldo MC, Co-distribution of sensory gating and impaired niacin flush response in the parents of schizophrenics. Schizophrenia research. 40:49-53, Nov 1999 PubMed ID: 10541007
Myles-Worsley M, Coon H, McDowell J, Brenner C, Hoff M, Lind B, Bennett P, Freedman R, Clementz B, Byerley W, Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families. American journal of medical genetics. 88:544-50, Oct 1999 PubMed ID: 10490714
Staley KJ, Proctor WR, Modulation of mammalian dendritic GABA(A) receptor function by the kinetics of Cl- and HCO3- transport. The Journal of physiology. 519 Pt 3:693-712, Sep 1999 PubMed ID: 10457084
Freedman R, Schizophrenia as a neuronal illness. Biological psychiatry. 46:587-8, Sep 1999 PubMed ID: 10472412
Khakh BS, Proctor WR, Dunwiddie TV, Labarca C, Lester HA, Allosteric control of gating and kinetics at P2X(4) receptor channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. 19:7289-99, Sep 1999 PubMed ID: 10460235
Adler LE, Olincy A, Waldo M, Harris JG, Griffith J, Stevens K, Flach K, Nagamoto H, Bickford P, Leonard S, Freedman R, Schizophrenia, sensory gating, and nicotinic receptors. Schizophrenia bulletin. 24:189-202, 1998 PubMed ID: 9613620
Jensen J, Coon H, Hoff M, Rosenthal J, Reimherr F, Wender P, Myles-Worsley M, Freedman R, Byerley W, Search for a schizophrenia susceptibility gene on chromosome 13. Psychiatric genetics. 8:239-43, 1998 PubMed ID: 9861643
Stevens KE, Kem WR, Mahnir VM, Freedman R, Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology. 136:320-7, Apr 1998 PubMed ID: 9600576
Soldo BL, Proctor WR, Dunwiddie TV, Ethanol selectively enhances the hyperpolarizing component of neocortical neuronal responses to locally applied GABA. Brain research. 800:187-97, Aug 1998 PubMed ID: 9685636
Ross RG, Harris JG, Olincy A, Radant A, Adler LE, Freedman R, Familial transmission of two independent saccadic abnormalities in schizophrenia. Schizophrenia research. 30:59-70, Feb 1998 PubMed ID: 9542789
Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV, Acetylcholine activates an alpha-bungarotoxin-sensitive nicotinic current in rat hippocampal interneurons, but not pyramidal cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 18:1187-95, Feb 1998 PubMed ID: 9454829
Stevens KE, Nagamoto H, Johnson RG, Adams CE, Rose GM, Kainic acid lesions in adult rats as a model of schizophrenia: changes in auditory information processing. Neuroscience. 82:701-8, Feb 1998 PubMed ID: 9483529
Leonard S, Gault J, Moore T, Hopkins J, Robinson M, Olincy A, Adler LE, Cloninger CR, Kaufmann CA, Tsuang MT, Faraone SV, Malaspina D, Svrakic DM, Freedman R, Further investigation of a chromosome 15 locus in schizophrenia: analysis of affected sibpairs from the NIMH Genetics Initiative. American journal of medical genetics. 81:308-12, Jul 1998 PubMed ID: 9674976
Leonard S, Gault J, Moore T, Hopkins J, Robinson M, Olincy A, Adler LE, Cloninger CR, Kaufmann CA, Tsuang MT, Faraone SV, Malaspina D, Svrakic DM, Freedman R, Further investigation of a chromosome 15 locus in schizophrenia: analysis of affected sibpairs from the NIMH Genetics Initiative. American journal of medical genetics. 81:308-12, Jul 1998 PubMed ID: 9674976
Griffith JM, O'Neill JE, Petty F, Garver D, Young D, Freedman R, Nicotinic receptor desensitization and sensory gating deficits in schizophrenia. Biological psychiatry. 44:98-106, Jul 1998 PubMed ID: 9646891
Leonard S, Gault J, Adams C, Breese CR, Rollins Y, Adler LE, Olincy A, Freedman R, Nicotinic receptors, smoking and schizophrenia. Restorative neurology and neuroscience. 12:195-201, Jun 1998 PubMed ID: 12671315
Freedman R, Adler LE, Nagamoto HT, Waldo MC, Selection of digital filtering parameters and P50 amplitude. Biological psychiatry. 43:921-2, Jun 1998 PubMed ID: 9627749
Gilchrist A, Mazzoni MR, Dineen B, Dice A, Linden J, Proctor WR, Lupica CR, Dunwiddie TV, Hamm HE, Antagonists of the receptor-G protein interface block Gi-coupled signal transduction. The Journal of biological chemistry. 273:14912-9, Jun 1998 PubMed ID: 9614095
Olincy A, Ross RG, Young DA, Roath M, Freedman R, Improvement in smooth pursuit eye movements after cigarette smoking in schizophrenic patients. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 18:175-85, Mar 1998 PubMed ID: 9471115
Johnson RG, Stevens KE, Rose GM, 5-Hydroxytryptamine2 receptors modulate auditory filtering in the rat. The Journal of pharmacology and experimental therapeutics. 285:643-50, May 1998 PubMed ID: 9580608
Warren S, Ross RG, Deficient cancellation of the vestibular ocular reflex in schizophrenia. Schizophrenia research. 34:187-93, Nov 1998 PubMed ID: 9850985
Adams CE, Stevens KE, Inhibition of nitric oxide synthase disrupts inhibitory gating of auditory responses in rat hippocampus. The Journal of pharmacology and experimental therapeutics. 287:760-5, Nov 1998 PubMed ID: 9808707
Freedman R, Biological phenotypes in the genetics of schizophrenia. Biological psychiatry. 44:939-40, Nov 1998 PubMed ID: 9821557
Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Freedman R, Anticipatory saccades during smooth pursuit eye movements and familial transmission of schizophrenia. Biological psychiatry. 44:690-7, Oct 1998 PubMed ID: 9798072
Smith DA, Hoffman AF, David DJ, Adams CE, Gerhardt GA, Nicotine-evoked nitric oxide release in the rat hippocampal slice. Neuroscience letters. 255:127-30, Oct 1998 PubMed ID: 9832189
Prochazka AV, Weaver MJ, Keller RT, Fryer GE, Licari PA, Lofaso D, A randomized trial of nortriptyline for smoking cessation. Archives of internal medicine. 158:2035-9, Oct 1998 PubMed ID: 9778204
Gault J, Robinson M, Berger R, Drebing C, Logel J, Hopkins J, Moore T, Jacobs S, Meriwether J, Choi MJ, Kim EJ, Walton K, Buiting K, Davis A, Breese C, Freedman R, Leonard S, Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics. 52:173-85, Sep 1998 PubMed ID: 9782083
Stevens KE, Wear KD, Normalizing effects of nicotine and a novel nicotinic agonist on hippocampal auditory gating in two animal models. Pharmacology, biochemistry, and behavior. 57:869-74, Aug 1997 PubMed ID: 9259018
Stevens KE, Johnson RG, Rose GM, Rats reared in social isolation show schizophrenia-like changes in auditory gating. Pharmacology, biochemistry, and behavior. 58:1031-6, Dec 1997 PubMed ID: 9408210
Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W, Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proceedings of the National Academy of Sciences of the United States of America. 94:587-92, Jan 1997 PubMed ID: 9012828
Gould TJ, Adams CE, Bickford PC, Beta-adrenergic modulation of GABAergic inhibition in the deep cerebellar nuclei of F344 rats. Neuropharmacology. 36:75-81, Jan 1997 PubMed ID: 9144643
Olincy A, Young DA, Freedman R, Increased levels of the nicotine metabolite cotinine in schizophrenic smokers compared to other smokers. Biological psychiatry. 42:1-5, Jul 1997 PubMed ID: 9193735
Breese CR, Marks MJ, Logel J, Adams CE, Sullivan B, Collins AC, Leonard S, Effect of smoking history on [3H]nicotine binding in human postmortem brain. The Journal of pharmacology and experimental therapeutics. 282:7-13, Jul 1997 PubMed ID: 9223534
Boyson SJ, Adams CE, D1 and D2 dopamine receptors in perinatal and adult basal ganglia. Pediatric research. 41:822-31, Jun 1997 PubMed ID: 9167195
Adams CE, Freedman R, Nicotinic antagonist alpha-bungarotoxin binding to rat hippocampal neurons containing nitric oxide synthase. Brain research. 776:111-6, Nov 1997 PubMed ID: 9439802
Breese CR, Adams C, Logel J, Drebing C, Rollins Y, Barnhart M, Sullivan B, Demasters BK, Freedman R, Leonard S, Comparison of the regional expression of nicotinic acetylcholine receptor alpha7 mRNA and [125I]-alpha-bungarotoxin binding in human postmortem brain. The Journal of comparative neurology. 387:385-98, Oct 1997 PubMed ID: 9335422
Dunwiddie TV, Diao L, Proctor WR, Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 17:7673-82, Oct 1997 PubMed ID: 9315889
Olincy A, Ross RG, Youngd DA, Freedman R, Age diminishes performance on an antisaccade eye movement task. Neurobiology of aging. 18:483-9, Sep 1997 PubMed ID: 9390774
Brundege JM, Diao L, Proctor WR, Dunwiddie TV, The role of cyclic AMP as a precursor of extracellular adenosine in the rat hippocampus. Neuropharmacology. 36:1201-10, Sep 1997 PubMed ID: 9364475
Lijam N, Paylor R, McDonald MP, Crawley JN, Deng CX, Herrup K, Stevens KE, Maccaferri G, McBain CJ, Sussman DJ, Wynshaw-Boris A, Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell. 90:895-905, Sep 1997 PubMed ID: 9298901
Leonard S, Adams C, Breese CR, Adler LE, Bickford P, Byerley W, Coon H, Griffith JM, Miller C, Myles-Worsley M, Nagamoto HT, Rollins Y, Stevens KE, Waldo M, Freedman R, Nicotinic receptor function in schizophrenia. Schizophrenia bulletin. 22:431-45, 1996 PubMed ID: 8873294
Young DA, Waldo M, Rutledge JH, Freedman R, Heritability of inhibitory gating of the P50 auditory-evoked potential in monozygotic and dizygotic twins. Neuropsychobiology. 33:113-7, 1996 PubMed ID: 8776738
Breese CR, Logel J, Adams C, Leonard SS, Regional gene expression of the glutamate receptor subtypes GluR1, GluR2, and GluR3 in human postmortem brain. Journal of molecular neuroscience : MN. 7:277-89, 1996 PubMed ID: 8968949
Stevens KE, Luthman J, Lindqvist E, Johnson RG, Rose GM, Effects of neonatal dopamine depletion on sensory inhibition in the rat. Pharmacology, biochemistry, and behavior. 53:817-23, Apr 1996 PubMed ID: 8801583
Stevens KE, Freedman R, Collins AC, Hall M, Leonard S, Marks MJ, Rose GM, Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 15:152-62, Aug 1996 PubMed ID: 8840351
Nagamoto HT, Adler LE, Hea RA, Griffith JM, McRae KA, Freedman R, Gating of auditory P50 in schizophrenics: unique effects of clozapine. Biological psychiatry. 40:181-8, Aug 1996 PubMed ID: 8830951
Flach KA, Adler LE, Gerhardt GA, Miller C, Bickford P, MacGregor RJ, Sensory gating in a computer model of the CA3 neural network of the hippocampus. Biological psychiatry. 40:1230-45, Dec 1996 PubMed ID: 8959288
Freedman R, Adler LE, Myles-Worsley M, Nagamoto HT, Miller C, Kisley M, McRae K, Cawthra E, Waldo M, Inhibitory gating of an evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Human recordings, computer simulation, and an animal model. Archives of general psychiatry. 53:1114-21, Dec 1996 PubMed ID: 8956677
Ross RG, Hommer D, Radant A, Roath M, Freedman R, Early expression of smooth-pursuit eye movement abnormalities in children of schizophrenic parents. Journal of the American Academy of Child and Adolescent Psychiatry. 35:941-9, Jul 1996 PubMed ID: 8768356
Harris JG, Adler LE, Young DA, Cullum CM, Rilling LM, Cicerello A, Intemann PM, Freedman R, Neuropsychological dysfunction in parents of schizophrenics. Schizophrenia research. 20:253-60, Jul 1996 PubMed ID: 8827851
Breese CR, D'Costa A, Rollins YD, Adams C, Booze RM, Sonntag WE, Leonard S, Expression of insulin-like growth factor-1 (IGF-1) and IGF-binding protein 2 (IGF-BP2) in the hippocampus following cytotoxic lesion of the dentate gyrus. The Journal of comparative neurology. 369:388-404, Jun 1996 PubMed ID: 8743420
Ward PB, Hoffer LD, Liebert BJ, Catts SV, O'Donnell M, Adler LE, Replication of a P50 auditory gating deficit in Australian patients with schizophrenia. Psychiatry research. 64:121-35, Sep 1996 PubMed ID: 8912954
Staley KJ, Soldo BL, Proctor WR, Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors. Science. 269:977-81, Aug 1995 PubMed ID: 7638623
Waldo M, Myles-Worsley M, Madison A, Byerley W, Freedman R, Sensory gating deficits in parents of schizophrenics. American journal of medical genetics. 60:506-11, Dec 1995 PubMed ID: 8825886
Adams CE, DeMasters BK, Freedman R, Regional zinc staining in postmortem hippocampus from schizophrenic patients. Schizophrenia research. 18:71-7, Dec 1995 PubMed ID: 8929763
Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV, Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcoholism, clinical and experimental research. 19:226-32, Feb 1995 PubMed ID: 7771653
Harris JG, Cullum CM, Puente AE, Effects of bilingualism on verbal learning and memory in Hispanic adults. Journal of the International Neuropsychological Society : JINS. 1:10-6, Jan 1995 PubMed ID: 9375204
Freedman R, Hall M, Adler LE, Leonard S, Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biological psychiatry. 38:22-33, Jul 1995 PubMed ID: 7548469
Cline EJ, Adams CE, Larson GA, Gerhardt GA, Zahniser NR, Medial dorsal striatum is more sensitive than lateral dorsal striatum to cocaine inhibition of exogenous dopamine clearance: relation to [3H]mazindol binding, but not striosome/matrix. Experimental neurology. 134:135-49, Jul 1995 PubMed ID: 7672034
Breese CR, Freedman R, Leonard SS, Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers. Brain research. 674:82-90, Mar 1995 PubMed ID: 7773698
Khan AS, Freedman R, Byerley W, Leonard S, Temperature gradient gel electrophoresis analysis of the beta-NGF gene in schizophrenia. Journal of psychiatry & neuroscience : JPN. 20:199-209, May 1995 PubMed ID: 7786881
Stevens KE, Meltzer J, Rose GM, Nicotinic cholinergic normalization of amphetamine-induced loss of auditory gating in freely moving rats. Psychopharmacology. 119:163-70, May 1995 PubMed ID: 7659763
Miller CL, Freedman R, The activity of hippocampal interneurons and pyramidal cells during the response of the hippocampus to repeated auditory stimuli. Neuroscience. 69:371-81, Nov 1995 PubMed ID: 8552235
Griffith J, Hoffer LD, Adler LE, Zerbe GO, Freedman R, Effects of sound intensity on a midlatency evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Psychophysiology. 32:460-6, Sep 1995 PubMed ID: 7568640
Griffith JM, Adler LE, Freedman R, Fine motor performance in schizophrenia. Neuropsychobiology. 29:179-84, 1994 PubMed ID: 8047244
Ross RG, Radant AD, Young DA, Hommer DW, Saccadic eye movements in normal children from 8 to 15 years of age: a developmental study of visuospatial attention. Journal of autism and developmental disorders. 24:413-31, Aug 1994 PubMed ID: 7961328
Adams CE, Hoffman AF, Hudson JL, Hoffer BJ, Boyson SJ, Chronic treatment with levodopa and/or selegiline does not affect behavioral recovery induced by fetal ventral mesencephalic grafts in unilaterally 6-hydroxydopamine-lesioned rats. Experimental neurology. 130:261-8, Dec 1994 PubMed ID: 7867755
Ross RG, Hommer D, Breiger D, Varley C, Radant A, Eye movement task related to frontal lobe functioning in children with attention deficit disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 33:869-74, Jul 1994 PubMed ID: 8083144
Spitz MC, Towbin JA, Shantz D, Adler LE, Risk factors for burns as a consequence of seizures in persons with epilepsy. Epilepsia. 35:764-7, Jul 1994 PubMed ID: 8082619
Adler LE, Hoffer L, Nagamoto HT, Waldo MC, Kisley MA, Giffith JM, Yohimbine impairs P50 auditory sensory gating in normal subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 10:249-57, Jul 1994 PubMed ID: 7945735
Waldo MC, Cawthra E, Adler LE, Dubester S, Staunton M, Nagamoto H, Baker N, Madison A, Simon J, Scherzinger A, Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings. Schizophrenia research. 12:93-106, May 1994 PubMed ID: 8043530
Freedman R, Adler LE, Bickford P, Byerley W, Coon H, Cullum CM, Griffith JM, Harris JG, Leonard S, Miller C, Schizophrenia and nicotinic receptors. Harvard review of psychiatry. 2:179-92, Nov 1994 PubMed ID: 9384901
Soldo BL, Proctor WR, Dunwiddie TV, Ethanol differentially modulates GABAA receptor-mediated chloride currents in hippocampal, cortical, and septal neurons in rat brain slices. Synapse (New York, N.Y.) 18:94-103, Oct 1994 PubMed ID: 7839317
Cullum CM, Harris JG, Waldo MC, Smernoff E, Madison A, Nagamoto HT, Griffith J, Adler LE, Freedman R, Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophrenia research. 10:131-41, Aug 1993 PubMed ID: 8398945
Adler LE, Hoffer LD, Wiser A, Freedman R, Normalization of auditory physiology by cigarette smoking in schizophrenic patients. The American journal of psychiatry. 150:1856-61, Dec 1993 PubMed ID: 8238642
Stevens KE, Meltzer J, Rose GM, Disruption of sensory gating by the alpha 2 selective noradrenergic antagonist yohimbine. Biological psychiatry. 33:130-2, Jan 1993 PubMed ID: 8439602
Ross RG, Radant AD, Hommer DW, A developmental study of smooth pursuit eye movements in normal children from 7 to 15 years of age. Journal of the American Academy of Child and Adolescent Psychiatry. 32:783-91, Jul 1993 PubMed ID: 8340299
Lin LH, Leonard S, Harris RA, Enflurane inhibits the function of mouse and human brain phosphatidylinositol-linked acetylcholine and serotonin receptors expressed in Xenopus oocytes. Molecular pharmacology. 43:941-8, Jun 1993 PubMed ID: 8316225
Leonard S, Logel J, Luthman D, Casanova M, Kirch D, Freedman R, Biological stability of mRNA isolated from human postmortem brain collections. Biological psychiatry. 33:456-66, Mar 1993 PubMed ID: 8098224
Johnson MR, Adler LE, Transient impairment in P50 auditory sensory gating induced by a cold-pressor test. Biological psychiatry. 33:380-7, Mar 1993 PubMed ID: 8386006
Browning MD, Dudek EM, Rapier JL, Leonard S, Freedman R, Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biological psychiatry. 34:529-35, Oct 1993 PubMed ID: 8274580
Griffith JM, Waldo M, Adler LE, Freedman R, Normalization of auditory sensory gating in schizophrenic patients after a brief period for sleep. Psychiatry research. 49:29-39, Oct 1993 PubMed ID: 8140180
Hoffer BJ, Leenders KL, Young D, Gerhardt G, Zerbe GO, Bygdeman M, Seiger A, Olson L, Strömberg I, Freedman R, Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Experimental neurology. 118:243-52, Dec 1992 PubMed ID: 1306484
Ross RG, Ward NG, Bromocriptine abuse. Biological psychiatry. 31:404-6, Feb 1992 PubMed ID: 1558903
Larson EW, Olincy A, Rummans TA, Morse RM, Disulfiram treatment of patients with both alcohol dependence and other psychiatric disorders: a review. Alcoholism, clinical and experimental research. 16:125-30, Feb 1992 PubMed ID: 1558293
Dunwiddie TV, Taylor M, Heginbotham LR, Proctor WR, Long-term increases in excitability in the CA1 region of rat hippocampus induced by beta-adrenergic stimulation: possible mediation by cAMP. The Journal of neuroscience : the official journal of the Society for Neuroscience. 12:506-17, Feb 1992 PubMed ID: 1311033
Proctor WR, Allan AM, Dunwiddie TV, Brain region-dependent sensitivity of GABAA receptor-mediated responses to modulation by ethanol. Alcoholism, clinical and experimental research. 16:480-9, Jun 1992 PubMed ID: 1320806
Proctor WR, Soldo BL, Allan AM, Dunwiddie TV, Ethanol enhances synaptically evoked GABAA receptor-mediated responses in cerebral cortical neurons in rat brain slices. Brain research. 595:220-7, Nov 1992 PubMed ID: 1334772
Adler LE, Hoffer LJ, Griffith J, Waldo MC, Freedman R, Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biological psychiatry. 32:607-16, Oct 1992 PubMed ID: 1450287
Miller CL, Bickford PC, Luntz-Leybman V, Adler LE, Gerhardt GA, Freedman R, Phencyclidine and auditory sensory gating in the hippocampus of the rat. Neuropharmacology. 31:1041-8, Oct 1992 PubMed ID: 1436386
Lupica CR, Proctor WR, Dunwiddie TV, Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro. Brain research. 593:226-38, Oct 1992 PubMed ID: 1360320
Lupica CR, Proctor WR, Dunwiddie TV, Presynaptic inhibition of excitatory synaptic transmission by adenosine in rat hippocampus: ana |
