Department of Psychiatry

Developmental Research

Cheek Swab

Genetics and environment both play a role in how our brains work. The role that genetics plays is complex—it is the combination of several genes that is important, with no single gene alone making a major difference. We are trying to understand how different genes interact and contribute to how a brain grows and functions, and, eventually, how genes create a vulnerability to psychiatric illnesses. To study the roles of various genes, we obtain a DNA sample from our research participants. We use a soft brush, similar to a soft-headed toothbrush, and gently swab the inside of the infant's cheeks to obtain the DNA sample.

The DNA sample will not be used to determine paternity or to find genetic defects. Only with your permission will some of the DNA be sent to a federally funded repository where this information can be used by scientists all over the world. These repositories provide a great service for researchers as they contain quantities of information that each researcher alone would not have the resources or time to collect. The repository gives the researcher a larger sample size and access to comparison group samples that they would not have if not for the repository. When your information is entered into the repository, it is stripped of all personal identifiable information, meaning that the scientists accessing the information can never trace the DNA back you or your child. In other words, you and your child's identity will remain anonymous.

Although this procedure is harmless to your child, some babies are uncomfortable with something being put inside their mouths. Some babies may cry during this short procedure. However, the procedure is not painful and and only lasts a few seconds.

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