Department of Psychiatry

Division of Substance Dependence

Christian J. Hopfer, M.D.
Associate Professor

 


UCD, Department of Psychiatry
4200 E. Ninth Avenue; Box C-268-35
Denver, CO 80262
Tel: 303-315-0798
Fax: 303-315-0394
christian.hopfer@uchsc.edu

 

 

 

Major Academic Interests
Honors
  • Behavioral genetics
  • Substance dependence and conduct disorders

  • AACAP Task Force of Substance Abuse Education and Research
  • Urban Peak Service Award, 2004
  • Colorado Child and Adolescent Psychiatric Society Service Award, 2003

Curriculum Vitae

Recent Publications/Presentations

Hopfer CJ, Lessem JM, Hartman CA, Cherny SS, Corley RP, Hewitt JK, Krauter KS, Mikulich-Gilbertson SK, Rhee SH, Smolen A, Young SE, Crowley TJ. A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: Evidence for linkage on chromosomes 3 and 9. Drug and Alcohol Dependence 2007 89 1:34-41.

Hartman CA, Gelhorn H, Crowley TJ, Sakai J, Stallings MC, Young SE, Corley R, Hewitt JK, Hopfer CJ. An Item Response Theory Analysis of DSM-IV Marijuana Abuse and Dependence Criteria in Adolescents. (In Press), Journal of the American Academy of Child and Adolescent Psychiatry.

Hopfer CJ, Young SE, Purcell S, Crowley TJ, Stallings MC, Corley RP, Rhee SH, Smolen A, Krauter K, Hewitt JK, Ehringer MA. Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents. American Journal of Medical Genetics – Neuropsychiatric Genetics 2006; 141B:895-901.

Current & Ongoing Research Support

Title: A Family Study of Substance Use and Conduct Disorder
This is a family study of adjudicated adolescent boys and girls with Substance Use and Conduct Disorder. Its primary aims are to test competing models of the comorbidity between Substance Use and Conduct Disorder and to examine the familial transmission of these disorders.
Role: Principal Investigator
R01 DA015522
NIH/NIDA
Dates: 07/01/2003 - 06/30/2008

Title: The National Longitudinal Study of Adolescent Health
The National Longitudinal Study of Adolescent Health (Add Health) is a longitudinal study of a nationally representative sample of more than 20,000 adolescents in grades 7-12 in the United States in 1994-95 who have been followed through adolescence and the transition to adulthood with three in home interviews. The fourth follow-up interview with the Add Health cohort is being conducted in 2007-08 when survey respondents will be aged 24-32. A series of analytic subprojects represents an interdisciplinary research program entitled "Add Health Wave IV: Social, Behavioral, and Biological Linkages."
Role: Co–Investigator
2P01HD031921-11A1
NIH/NIHCD
Dates: 03/01/1997 - 12/31/2010

Title: NIAAA Institutional Postdoctoral Training Grant: Behavioral Pharmacokinetics of Drug and Alcohol Abuse
The major goal of this project is to produce well-trained independent researchers in the area of alcohol effects, alcoholism, and drug abuse. Dr. Hopfer acts a preceptor for post-doctoral trainees.
Role: Preceptor
5 T32 AA 007464-31
NIH/NIAAA
Dates: 07/1/2007 - 06/30/2011

Title: Development of Maladaptive Behavior
This NIMH Training grant’s primary purpose is to train clinician-scientists in the area of the development of maladaptive behavior. Dr. Hopfer is on the program faculty and acts as a preceptor for post-doctoral trainees.
Role: Preceptor
5 T32 MH15442-29
NIH/NIMH
Dates: 07/1/1978 - 06/30/2011

Completed Research Support

Title: Genetics of Major Depression and Bipolar Disorder
We are currently conducting a pilot study examining the role of adenyl cyclase polymorphisms in the etiology of major depression and bipolar illness.
Banbury Foundation (Tabakoff) / $30,000
2003 - 2006

Title: Contingency Based Treatment and Housing for Young Adults
DHHS, Public Health Service, Substance Abuse and Mental Health Services Administration. Center for Substance Abuse Treatment. Contingency Based Treatment and Housing for Young Adults. Dr. Hopfer is acting as the program evaluator for this model program which provides contingency-based housing for homeless young adults with substance dependence.
5 H79TI14373–03 (Brewster) / CSAT / $504,397
06/01/2003 - 05/30/2006             

Educational Activities

Medical Students:
Tutor, The Big Six Substance Problems in Primary Care Medicine, 8001 elective course for medical students, University of Colorado School of Medicine, 1999 – Present. Present to 1-2, 4th year medical students on “Motivational Interviewing” approximately every 4 weeks.

Mentor, Psychiatry Scholars Program, Division Faculty serve as mentors to medical students wishing to fulfill their independent learning requirement.

Psychiatric Residents:
Adolescent Substance Use Disorders and Comorbidity
, subspeciality clinic and clinical course of PGYIV child psychiatry residents, University of Colorado School of Medicine, 1999 – Present. This course trains PGY-IV residents in the etiology, diagnosis, and management of adolescent substance use Disorders.

Introduction to Substance Dependence, PGYIII course for psychiatric residents, 1999 - Present. This course trains PGYIII residents in the etiology, diagnosis, and management of substance abuse disorders. Annually present one or two lectures of “Motivational Interviewing.” Scheduled Lectures in 2007.

Psychotherapy Curriculum, PGYIII course for psychiatry residents, 1999-Present. Annually present lectures on psychotherapy techniques to engage treatment-resistant clients.

Addiction Fellows:
PGY V residents in addiction psychiatry, ARTS, weekly from: 2001 – 2003 & 2005 – Present.  

Opportunities for Research Participation of Medical Students and Residents:
Medical Students: In the Division’s research elective, Psychiatry 8610, or Psychiatry Scholars Program, students will work on projects currently pursued by Division faculty, or in associated labs on the CU-Boulder campus.

Residents: Residents can arrange individual electives with Dr. Hopfer and become involved in research training at various levels.

 
 

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