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PROFESSIONAL EXPERIENCE
1992-1996
Postdoctoral Research Associate, Webb-Waring Institute for Biomedical Research, University of Colorado Denver, Denver, CO
1993-present
Guest Researcher, National Institute of Standards and Technology, Department of Commerce, Boulder, CO
1996-present
Assistant Professor, Webb-Waring Institute for Biomedical Research, Department of Medicine, Division of Pulmonary and Critical Care Medicine, School of Medicine, University of Colorado Denver, Denver, CO
HONORS
Reviewer, Veterans Health Administration, 1998
Parker B. Francis Foundation Fellowship, 1993-1996
The Oxygen Society Young Investigators Award, 1993
Colorado Doctoral Fellowship, 1986
Phi Beta Kappa, 1985
SELECTED PUBLICATIONS
- B. M. Hybertson, J. E. Repine, C. J. Beehler, K. Suchari Rutledge, A. F. Lagalante, and R. E. Sievers, Pulmonary Drug Delivery of Fine Aerosol Particles from Supercritical Fluids, Journal of Aerosol Medicine 6, 275-286 (1993).
- J. A. Leff, C. P. Wilke, B. M. Hybertson, P. F. Shanley, C. J. Beehler, and J. E. Repine, Post-Insult Treatment with N-Acetylcysteine Decreases IL-1-Induced Neutrophil Influx and Lung Leak in Rats, American Journal of Physiology 265, L501-L506 (1993).
- B. M. Hybertson, A. J. Dunham, D. C. Thompson, L. S. Terada, and J. E. Repine, Flow Injection Analysis of Nitrite Generated by Neutrophils and Endothelial Cells, Analytical Letters 27 (15), 3081-3093 (1994).
- B. M. Hybertson, J. A. Leff, C. J. Beehler, P. C. Barry, and J. E. Repine, Effect of Vitamin E Deficiency and Supercritical Fluid Aerosolized Vitamin E Supplementation on Interleukin-1-Induced Oxidative Lung Injury in Rats, Free Radical Biology & Medicine 18, 537-542 (1995).
- Y. Koh, B. M. Hybertson, E. K. Jepson, O. J. Cho, and J. E. Repine, Cytokine-Induced Neutrophil Chemoattractant is Necessary for Interleukin-1-Induced Lung Leak in Rats, Journal of Applied Physiology 79, 472-478 (1995).
- D. M. Guidot, M. J. Repine, B. M. Hybertson, and J. E. Repine, Inhaled Nitric Oxide Prevents Neutrophil-Mediated, Oxygen Radical-Dependent Leak in Isolated Rat Lungs, American Journal of Physiology 269, L2-L5 (1995).
- B. M. Hybertson, J. A. Leff, and J. E. Repine, Interleukin-1, Oxidant-Antioxidant Balance, and Acute Lung Injury. In: The Oxygen Paradox (Davies, K. J. A. and Ursini, F., eds.) CLEUP University Press, Padova, Italy, pp. 763-772 (1995).
- B. M. Hybertson, A. S. Lampey, J. H. Clarke, Y. Koh, and J. E. Repine, N-Acetylcysteine Pretreatment Attenuates Paraquat-Induced Lung Leak in Rats, Redox Report 1, 337-342 (1995).
- B. M. Hybertson, E. K. Jepson, J. H. Clarke, R. J. Spelts, and J. E. Repine, Interleukin-1 Stimulates Rapid Release of Cytokine-Induced Neutrophil Chemoattractant (CINC) in Rat Lungs, Inflammation 20, 471-483 (1996).
- D. M. Guidot, B. M. Hybertson, R. G. Kitlowski, and J. E. Repine, Inhaled NO Prevents IL-1-Induced Neutrophil Accumulation and Associated Edema in Isolated Rat Lungs, American Journal of Physiology 271, L225-L229 (1996).
- Y. Koh, B. M. Hybertson, E. K. Jepson, and J. E. Repine, Tumor Necrosis Factor Induced Acute Lung Leak in Rats: Less Than With Interleukin-1, Inflammation 20 461-469 (1996).
- B. M. Hybertson and J. E. Repine, Interleukin-1-Mediated Acute Lung Injury. In: Yearbook of Intensive Care and Emergency Medicine 1997 (Vincent, J.-L., ed.) Springer-Verlag, Heidelberg, Germany, 74-82 (1997).
- B. M. Hybertson, S. L. Bursten, J. A. Leff, Y. M. Lee, E. K.. Jepson, C. R. DeWitt, J. Zagorski, H. G. Cho, and J. E. Repine, Lisofylline Prevents Leak, but Not Neutrophil Accumulation, in Lungs of Rats Given IL-1 Intratracheally, Journal of Applied Physiology 82, 226-232 (1997).
- L. S. Terada, B. M. Hybertson, K. G. Connelly, D. Weill, D. Piermattei, and J. E. Repine, Xanthine Oxidase Increases Neutrophil Adherence to Endothelial Cells by a Dual ICAM-1 and P-Selectin-Mediated Mechanism, Journal of Applied Physiology 82, 866-873 (1997).
- L. S. Terada, J. E. Repine, D. Piermattei, and B. M. Hybertson, Endogenous Nitric Oxide Decreases Xanthine Oxidase-Mediated Neutrophil Adherence. Role of P-Selectin, Journal of Applied Physiology 82, 913-917 (1997).
- Y. M. Lee, B. M. Hybertson, L. S. Terada, A. J. Repine, H. G. Cho, and J. E. Repine, Mepacrine Decreases Lung Leak in Rats Given IL-1 Intratracheally, American Journal of Respiratory and Critical Care Medicine 155, 1624-1628 (1997).
- B. M. Hybertson, Y. M. Lee, E. K. Jepson, O. J. Cho, J. H. Clarke, and J. E. Repine, TNF Mediates Lung Leak, but Not Neutrophil Accumulation, in Lungs of Rats Given IL-1 Intratracheally, American Journal of Respiratory and Critical Care Medicine 155, 1972-1976 (1997).
- D. M. Guidot, S. L. Bursten, G. C. Rice, R. B. Chaney, J. W. Singer, A. J. Repine, B. M. Hybertson, and J. E. Repine, Modulating Phosphatidic Acid Metabolism Decreases Oxidative Injury in Rat Lungs, American Journal of Physiology 273, L957-L966 (1997).
- B. M. Hybertson, Y. M. Lee, and J. E. Repine, Interleukin-1, Phagocytes, and Acute Lung Injury, Annals of the New York Academy of Sciences 832 (Phagocytes: Biology, Physiology, Pathology, and Pharmacotherapeutics, Rodolfo Paoletti, Antonia Notario & Giovanni Ricevuti, Eds.), 266-273 (1997).
- B. M. Hybertson, R. P. Kitlowski, E. K. Jepson, and J. E. Repine, Supercritical Fluid Aerosolized Vitamin E Pretreatment Decreases Leak in Isolated Rat Lungs Perfused with Xanthine Oxidase, Journal of Applied Physiology 84, 263-268 (1998).
- K. A. Stringer, B. M. Hybertson, O. J. Cho, Z. Cohen, and J. E. Repine, Tissue Plasminogen Activator (tPA) Inhibits Interleukin-1 Induced Acute Lung Leak, Free Radical Biology & Medicine 25, 184-188 (1998).
- B. M. Hybertson and J. E. Repine, Interleukin-1, Neutrophils, and Oxidants in Acute Lung Injury. In: Oxygen Radicals and the Disease Process (C.E. Thomas and S. Kalyanaraman, eds.) Harwood Academic Publishers Reading, Amsterdam, The Netherlands, 127-139 (1998).
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