Our laboratory works on structure and enzyme dynamics, and we are very good at purifying proteins.
Representative Publications:
Eisenmesser EZ, Thai V, Renesto, P, Fowler A, Brown D, Davis T, Gu W, Pollock DD, Kern D, Raoult D, "Structure and Dynamics of Pin1 During Catalysis by NMR." J Mol Biol. 2007
Labeikovsky W, Eisenmesser EZ, Bosco DA, Kern D., "Structure and Dynamics of Pin1 During Catalysis by NMR." J Mol Biol. 2007
Eisenmesser EZ, Millet O, Labeikovsky W, Korzhnev DM, Wolf-Watz M, Bosco DA, Skalicky JJ, Kay LE, Kern D., "Intrinsic dynamics of an enzyme underlies catalysis." Nature. 2005
Eisenmesser EZ, Bosco DA, Akke M, Kern D., "Enzyme dynamics during catalysis." Science. 2002
Eisenmesser EZ, Horita DA, Altieri AS, Byrd RA., "Solution structure of interleukin-13 and insights into receptor engagement." J Mol Biol. 2001
Eisenmesser EZ, Post CB., "Insights into tyrosine phosphorylation control of protein-protein association from the NMR structure of a band 3 peptide inhibitor bound to glyceraldehyde-3-phosphate dehydrogenase" Biochemistry. 1998
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