RESEARCH INTERESTS:
Obesity
Energy metabolism
Exercise
Body composition
Body weight regulation
UNIQUE TECHNIQUES/EQUIPMENT:
- Live-in whole room calorimeter for human subjects
- Rodent calorimeters
- Techniques for body composition analysis
- Techniques for insulin clamps in rodents
- Assessment of muscle and adipocyte metabolism
RECENT REPRESENTATIVE RESEARCH PUBLICATIONS:
- Horton TJ, Pagliassotti MJ, Hobbs K and Hill JO. Fuel metabolism in
males and females during and following long duration exercise. Journal of
Applied Physiology 85:1823-1835, 1998.
- Hill JO
. Genetic and environmental contributions to obesity. American
Journal of Clinical Nutrition 68:991-992, 1998.
- Sidney S, Lewis CE, Hill JO, Quesenberry CP, Jr., Stamm ER,
Scherzinger A, Tolan K, and Ettinger B. Association of total and central
adiposity measures with fasting insulin in a biracial population of young
adults with normal glucose tolerance: the CARDIA Study. Obesity Research
7:265-272, 1999.
- Kriketos AD, Sharp TA, Seagle HM, Grunwald G. and Hill JO. Effects
of aerobic physical fitness on fat oxidation and body fatness. Medicine
& Science in Sports & Exercise 32:805-811, 2000.
- Commerford SR, Wei Y, Pagliassotti MJ, and Hill JO. Fat oxidation,
lipolysis, and free fatty acid cycling in obesity prone and obesity
resistant rats. American Journal of Physiology, in press 2000.
- Hill JO
. An overview of the etiology of obesity. In: Eating Disorders
and Obesity: A Comprehensive Handbook, 2nd Edition. C. Fairburn and
K. Brownell, eds. Guilford, New York, 2001.
RELATED ACTIVITIES:
Editorial Boards:
- American Journal of Physiology
- Obesity Research
Member NIH Taskforce on Prevention and Treatment of Obesity
Chair, Education Committee and council member of North American Association
for the Study of Obesity
Member, Nominating Committee, American Society for Clinical Nutrition, 1993
- present
LAY SUMMARY OF RESEARCH OBJECTIVES:
The focus of this laboratory is to identify mechanisms of body weight
regulation. Studies in human subjects and in rodents are aimed at identifying
the way in which energy metabolism is regulated at the whole body, tissue/organ
and molecular levels.
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