VAN PELT, Rachael E., PhD       Geriatric Medicine      Center on Aging, B179      303-315-4693      rachael.vanpelt@UCHSC.edu

• Endocrine regulation of tissue metabolism
• Whole body energy metabolism and body weight regulation
• Regional fat distribution and disease risk
• Aging
• Exercise

• Microdialysis for the assessment of interstitial tissue metabolism in vivo
• Hyperinsulinemic, euglycemic clamps and isotope kinetics for the assessment of whole body and regional metabolism

• Van Pelt R.E., E.M. Evans, K.B. Schechtman, A.A. Ehsani, and W.M. Kohrt. Contributions of total and regional fat mass to risk for cardiovascular disease in older women.  Am J Physiol Endocrinol Metab 282: E1023-1028, 2002.

• Fisher, J.S., R.E. Van Pelt, Zinder, O., Landt, M. and Kohrt, W.M.  Acute exercise effect on postabsorptive serum leptin. J Appl Physiol 91(2):680-686, 2001.

• Evans, E.M., R.E. Van Pelt, E.F. Binder, D.B. Williams, A.A. Ehsani and W.M. Kohrt.  Effects of HRT and exercise training on body composition, glucose tolerance, and insulin action in older women J Appl Physiol 90:2033-2040, 2001.

• Van Pelt, R.E., K.P. Davy, E.T. Stevenson, P.P. Jones, Teresa M. Wilson, C.A. DeSouza and D.R. Seals.  Smaller differences in total and regional adiposity with age in regularly exercising compared with sedentary women.  Am J Physiol Endocrinol Metab 275(4 pt 1): E626-E634, 1998.

• Van Pelt, R.E., P.P. Jones, K.P. Davy, C.A. DeSouza, H. Tanaka, B.M. Davy and D.R. Seals.  Regular exercise and the age-related decline in resting metabolic rate in women.  J Clin Endrocrinol  Metab  82:3208-3212, 1997.

Increases in body fat that occur aging and inactivity lead to a number of common metabolic diseases such as obesity, diabetes mellitus and poor cholesterol. Research is carried out to study how metabolism differs in various regions of the body; also, how aging, exercise and hormones affect metabolism and body composition.

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