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Division of Medical Oncology
University of Colorado Denver
12801 E. 17th Avenue
Aurora, CO  80010
Ph:  (303) 724-3888
Fax:  (303  724-3889
info@deptofmed.edu


 



Lynne T. Bemis, PhD
Associate Professor
University of Colorado Cancer Center

Education:  Ph.D.
University of New Hampshire
Durham, NH – 1989

University of Colorado Denver
School of Medicine
Division of Medical Oncology
Tel: (303) 724-3888
Fax: (303) 724-3889
e-mail: lynne.bemis@uchsc.edu


Bio
Dr. Bemis has been actively conducting research in the Division of Medical Oncology for eight years.  Her research focus is on cancer biomarkers for early detection, diagnosis or prognosis.  Her current research interests include microRNA as biomarkers and the use of Nanotechnology for cancer detection.

Research
Dr. Bemis works closely with the melanoma and lung cancer programs to bring laboratory discoveries to clinical application.  Current projects include studies of microRNA in melanoma and lung cancer. MicroRNAs are small regulatory RNAs that regulate large programs of protein expression in all human cells but can be especially important in regulating pathways in cancer as well as being tissue specific, an advantage when considering their use as biomarkers.  Dr. Bemis is also working in the cutting edge field applying nanotechnology to cancer biomarkers.  Her recent focus in the nanotechnology area applies gold nanoparticles to the detection of point mutations in tumor tissue.  The focus of her program is to develop biomarkers for earlier cancer detection, diagnosis and prognosis.  

 

FACULTY LIST

Lynn Bemis
Virginia Borges
Paul Bunn
David Calverley
Ross Camidge
Dan Chan
Gail Eckhardt
Anthony Elias
Thomas Flaig
Marileila Garcia
L. Michael Glode
Rene Gonzalez
Barb Helfrich
Fred Hirsch
Christopher Hogan
Antonio Jimeno
Madeleine Kane
Choon-Kee Lee
Stephen Leong
Wells Messersmith
Han Myint
Ana Oton
Peter Raich
William Robinson
Pepper Schedin
John Tentler
William Tse
Colin Weekes

Publications
Publications
Bemis LT, Robinson WA, McFarlane R, Buyers E, Kelly K, Varella-Garcia M, Franklin WA. EGFR-mutant lung adenocarcinoma in a patient with Li-Fraumeni syndrome.  Lancet Oncology (2007) 8(6):559-60.

Cappuzzo, F., Varella-Garcia, M. And Bemis LT. HER2 mutation and response to trastuzumab therapy in non-small-cell lung cancer. N Engl J Med. (2006) 354(24):2619-21.

Bemis,L.T., Chen,R., Amato,C.M., Robinson,S.E., Classen,E.H., Coffey,D.G., Erickson,P.F. and Robinson,W.A.  microRNA-137 Targets Microphthalmia-associated Transcription Factor (MITF) Expression in Melanoma Cell Lines.  GenBank accession: EF660891.

Funding
National Science Foundation – Nanotechnology
Harry J. Lloyd Charitable Trust   --  MicroRNAs in Melanoma

PubMed articles

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