Division of Medical Oncology
University of Colorado Denver
12801 E. 17th Avenue
Aurora, CO 80010
Ph: (303) 724-3888
Fax: (303 724-3889 info@deptofmed.edu
Choon-Kee Lee, M.D.
Associate Professor, Medical Oncology
Director, Myeloma and Amyloidosis Program
Education: Chonnam National University
Chonnam, Korea – 1981
University of Colorado Denver
School of Medicine
Division of Medical Oncology
Tel: (720) 848-0713
Fax: (720) 848-0359
e-mail: ChoonKee.Lee@uchsc.edu
Bio
Dr Lee started with the University of Colorado in 2006. His areas of clinical interests and expertise are plasma cell dyscrasia, including multiple myeloma and amyloidosis. Non-myeloablative allogeneic stem cell transplantation and management of graft versus host disease by T lymphocyte manipulation, following allogeneic stem cell transplantation, are other interests.
Research
His research interests include epigenetic modulation on multiple myeloma to reverse resistance to DNA damaging agents. The first phase of the study focuses on laboratory investigations on myeloma cell lines, in collaboration with the Department of Pathology. Clinical investigations based on the laboratory findings will focus on development of innovative therapy for high-dose therapy with transplantation and for apoptotic management. Dr Lee is also developing a new strategy for treating patients with amyloidosis who may not be transplant candidates.
Publications Lee C.K., de Magalhaes-Silverman M., Hohl R.J., Hayashi M., Buatti J., Wen B.C., Schlueter A., Strauss R.G., Gingrich R.D.: Donor T lymphocyte infusion for unrelated allogeneic bone marrow transplantation with CD3+ T-cell-depleted graft. Bone Marrow Transplant 2003;31: 121-128.
Lee C.K., Barlogie B, Zangari M.E., Munshi NC, Fassas AB, van Rhee F., Cottler-Fox M., Muwalla F., Tricot, G.: D.T.PACE, an effective, novel combination chemotherapy with thalidomide for previously treated patients with myeloma. J Clin Oncol 2003; 21:2732-2739.
Lee C.K., Barlogie B, Zangari M.E., Fassas AB, Badros AS, van Rhee F., Cottler-Fox M., Thertulien R, Muwalla F., Anaissie E.J., Tricot G.: Dialysis-dependent renal failure in patients with myeloma can be reversed by high-dose myeloablative therapy and autotransplant. Bone Marrow Transplant 2004; 33:823-828.
