ST101

ANALYSIS OF ALTERED SCN5A ION CHANNEL FUNCTION IN THE ETIOLOGY OF DILATED CARDIOMYOPATHY

Authors:  WP McNair, L Mestroni, J Caldwell.

Division:  Cardiology

ST102

CHARACTERIZING A MODEL OF ESTROGEN-DEPENDENT BREAST CANCER LYMPHATIC METASTASIS

Authors:  J. Chuck Harrell, Wendy W. Dye, Carol A. Sartorius, Kathryn B. Horwitz

Division:  Endocrinology, Metabolism and Diabetes

ST103

BENIGN MCF-10A MAMMARY EPITHELIAL CELLS ENHANCE THE TUMORIGENICITY OF METASTATIC MDA-231 BREAST CANCER CELLS IN NUDE MICE XENOGRAFTS

Authors:  Joanna Poczobutt, John Tentler, Pepper Schedin, Arthur Gutierrez-Hartmann

Division:  Endocrinology, Metabolism and Diabetes

ST104

EXERCISE INTERVENTION OUTCOMES ON COGNITIVELY IMPAIRED AND INTACT OLDER ADULTS: A META-ANALYSIS

Authors:  Kyle Eugene Johnson, MSII, Patricia C. Heyn, PhD

Division:  Geriatrics

ST105

CASE REPORTS IN EMERGENCY MEDICINE RESEARCH: ARE THE METHODS VALID?

Authors:  T.P. Richason, BS; K.J. Heard, MD; S.M. Paulson, MD; and S.R. Lowenstein, MD, MPH. Division of Emergency Medicine, University of Colorado School of Medicine, Denver, CO

Division:  Health Care Policy & Research

ST106

THE COOPERATIVE EFFECTS OF SILIBININ, AN AGENT WITH ACTIVITY AGAINST GROWTH FACTOR SIGNALING IN COMBINATION WITH IONIZING RADIATION AGAINST HUMAN BLADDER CANCER

Authors:  Jeffrey R Buesing, Lih-Jen Su, David Raben, L. M. Glodé, and Thomas W. Flaig

Division:  Medical Oncology

ST107

ACUTE INTERSTITIAL PNEUMONITIS IN A PATIENT WITH A HISTORY OF HYPERSENSITIVITY PNEUMONITIS

Authors:  R. Todd Drexel, Joe Schuller M.D., William Janssen M.D.

Division:  Pulmonary Sciences and Critical Care

ST108

IMPAIRED IMMUNOGLOBULIN GENE (VH) SOMATIC HYPERMUTATION (SHM) AND ACTIVATION-INDUCED DEAMINASE (AID) EXPRESSION IN HIV INFECTION 

Authors:  Elisabeth Bowers, Kathryne Keays, Lydie Beniguél, Anil Asrani, Ronald W. Scamurra, Samantha MaWhinney, Steven Liu, Edward N. Janoff. 

Division:  Infectious Diseases (Colorado Center for AIDS Research, Eastern Colorado Veterans Affairs Medical Center, Denver, CO)

HS101

LEFT VENTRICULAR NONCOMPACTIOIN ASSOCIATED WITH FRIEDREICHS ATAXIA

Authors:  Herman O. Lyle

Division:  Cardiology

HS102 

ARTERIOPORTAL FISTULA REQUIRING LIVER TRANSPLANTATION

Authors:  Jeffrey D. Duman, Stephen P. Johnson, James F. Trotter

Division:  Gastroenterology & Hepatology

HS103

DUODENAL CANCER – A RARE MALIGNANCY AND CAUSE OF PAINLESS JAUNDICE

Author:  Kelley T Moulds MD

Division:  Gastroenterology & Hepatology

HS104

HOW DO RESIDENTS INTERACT WITH PHARMACEUTICAL REPRESENTATIVES?

Authors:  Brian B. Graham MD, Suzanne Brandenburg MD
Division:  General Internal Medicine

HS105

COLONOSCOPY ADHERENCE IN A SAFETY NET HEALTH CARE SYSTEM

Authors:  Elina Kazarian, MD, Fernando Carreira, MD, Tom Denberg, MD/PhD

Division:  General Internal Medicine

HS106

AN UNUSUAL INGESTION

Author:  Nima Yazdani

Division:  General Internal Medicine

HS107

STRONGYLOIDES INFECTION COMPLICATED BY ADRENAL INSUFFICIENCY

Author:  Rachel Groff

Division:  General Internal Medicine

HS108

TWO CASES OF STRESS INDUCED CARDIOMYOPATHY

Author:  Joseph Schuller

Division:  General Internal Medicine

HS109

THE IMPORTANCE OF A METHODICAL WORKUP

Author:  Peter Stubenrauch

Division:  General Internal Medicine

HS110

BLAND-WHITE-GARLAND SYNDROME: ANOMALOUS ORIGIN OF THE LEFT CORONARY ARTERY FROM THE PULMONARY TRUNK.

Authors:  Elisa Carniel, Daniel Santillano, Alexandra Smart, Mark Geraci, Tristan Huie, Amy Martin

Division:  General Internal Medicine

HS111

BRAIN NATRIURETIC PEPTIDE: USEFULNESS IN DIAGNOSIS OF CONGESTIVE HEART FAILURE IN THE SETTING OF ACUTE DYSPNEA

Author:  Christina Adams, M.D.

Division:  General Internal Medicine

HS112

HYPERTHYROIDISM-INDUCED ATRIAL FIBRILLATION?

Author:  Svetlana Rivilis

Division:  General Internal Medicine

HS113

PREOPERATIVE A1c: A PREDICTOR OF MORBIDITY & MORTALITY IN ELECTIVE HIP ARTHROPLASTY

Authors:  Rebecca Sturges, Jeffrey Glasheen

Division:  General Internal Medicine

HS114

OUTPATIENT TREATMENT OF BACTEREMIA: A CASE OF DISSEMINATED GONORRHEA

Author:  Jaime Heberling, MD

Division:  General Internal Medicine

HS115

OSTEOARTICULAR SPORTRICHOSIS

Author:  Carrie Horn

Division:  Infectious Diseases

HS116

ACHES AND PAINS: EXPANDING YOUR DIFFERENTIAL

Author:  Chad Stickrath

Division:  Medical Oncology

HS117

MICRO RNA GENE REGULATION IN MANTLE CELL LYMPHOMA

Authors:  Sapna Patel MD, Robert Chen MD, William Robinson MD, Han Myint MD, Lynne Bemis PhD

Division:  Medical Oncology

HS118

A PROSPECTIVE RANDOMIZED STUDY OF HALOPERIDOL IN ADDITION TO STANDARD SEDATION IN DELIRIOUS AND INTUBATED PATIENTS: PRELIMINARY SAFETY ANALYSIS

Authors:  Brian B. Graham, MD, Ivor S. Douglas, MD

Division:  Pulmonary Sciences and Critical Care

HS119

TNF-A POLYMORPHISMS AND COPD

Authors:  Matthew R Gingo, Greg Kinney, Lisa Maier, Russell Bowler

Division:  Pulmonary Sciences and Critical Care

HS120

VASCULAR REGRESSION IDENTIFIES NON-REVERSIBLE AIRWAY INJURY CULMINATING IN FIBROSIS

Authors:  Ashok N Babu, MD, Tomohiro Murakawa, MD, Martin R Zamora, MD, Frederick Grover, MD and Mark R Nicolls, MD.

Division:  Pulmonary Sciences and Critical Care

FEL101 

REVERSAL OF HYPERGLYCEMIA IN A DIABETIC RAT AFTER IMPLANTATION OF PROINSULIN SECRETING FIBROBLASTS IN A THERACYTE® IMMUNOISOLATION DEVICE

Authors:  Min Zhang MD, Ashley Frazer-Abel PhD, Cherie Lambert PhD, Shannon Flannery, Brian Freed PhD DABHI

Division:  Allergy & Clinical Immunology

FEL102 

THE RELATIONSHIP BETWEEN EARLY FOLLOW-UP AFTER AMI AND EVIDENCE-BASED MEDICAL THERAPY: RESULTS OF THE PREMIER REGISTRY

Authors:  Stacie A. Luther, P. Michael Ho, John A. Spertus, Phil G. Jones, John S. Rumsfeld, Harlan M. Krumholz, William S. Weintraub, Edward P. Havranek, Richard G. Bach, Eric D. Peterson, Frederick A. Masoudi, Cardiovascular Outcomes Research Consortium, Denver, CO

Division:  Cardiology

FEL103 

ROTATIONAL VS. STANDARD QUANTITATIVE CORONARY ANGIOGRAPHY (QCA)

Authors:  Joel A. Garcia MD, Andrew J. Klein MD, Nathan E. Green MD, Todd Maddux MD, SY James Chen PhD, Adam Hansgen BS, John D. Messenger MD, Ivan P. Casserly MD, Onno Wink PhD*, Babak Movassaghi PhD*, Bertron M. Groves MD, and John D. Carroll MD
University of Colorado Hospital and Health Sciences Center
*Philips Medical Systems

Division:  Cardiology

FEL104 

A RARE PRESENTATION OF DUAL ACUTE STENT THROMBOSIS (AST) AND SINGLE CENTER EXPERIENCE IN SIROLIMUS AND PACLITAXEL STENT THROMBOSIS AFTER SUCCESSFUL STENT IMPLANTATION

Authors:  Joel A. Garcia MD, Adam Hansgen BS, John D. Messenger MD, Ivan P. Casserly MD, Bertron M. Groves MD, and John D. Carroll MD.

Division:  Cardiology

FEL105 

THIAZOLIDINEDIONE DRUGS BLOCK CARDIAC K(ATP) CHANNELS IN VIVO

Authors:  Li Lu, Michael J. Reiter, Ya Xu, Clifford Greyson, Gregory G. Schwartz

Division:  Cardiology

FEL 106

CYSTEINE PROTEASE INHIBITORS ATTENTUATE ACUTE RIGHT HEART FAILURE

Authors:  Hasan A. Ahmad, Gregory G. Schwartz, Li Lu, Shuyu Ye, Steve Helmke, Ya Xu, Clifford R. Greyson

Division:  Cardiology

FEL107 

THE USE OF SIMULATION-BASED TRAINING TO ENHANCE PATIENT SAFETY FOR CARDIAC CATHETERIZATION: A RANDOMIZED CONTROLLED MULTI-CENTER STUDY

Authors:  Andrew J. Klein, John C. Messenger, John Combes, John S. Rumsfeld, Phil Kletke, Samantha MaWhinney, Kathy Kioussopoulous and John D. Carroll

Division:  Cardiology

FEL108 

DETERMINATION OF OPTIMAL VIEWING ANGLES FOR X-RAY CORONARY ANGIOGRAPHY BASED ON A QUANTITATIVE ANALYSIS OF 3D RECONSTRUCTED MODELS

Authors:  Andrew J. Klein, Joel A. Garcia, Babak Movassaghi, Onno Wink, S.-Y. James Chen, John C. Messenger, Adam Hansgen, Nathan E. Green, John D. Carroll

Division:  Cardiology

FEL109 

MULTI-SLICE COMPUTERIZED TOMOGRAPHY ANGIOGRAPHY BASED THREE-DIMENSIONAL (3D) RECONSTRUCTION IN THE PLANNING OF PERCUTANEOUS CORONARY INTERVENTIONS-A NOVEL APPLICATION

Authors:  Andrew J. Klein, M.D., Joel A. Garcia, M.D., Alex Jehle, M.D., Babak Movassaghi, Ph.D., Onno Wink, Ph.D., S.-Y. James Chen, Ph.D., John C. Messenger, M.D., Adam Hansgen, B.S., Ivan P. Casserly, M.D., John D. Carroll, M.D.

Division:  Cardiology

FEL110 

QUANTIFICATION OF MOVEMENT-INDUCED CONFORMATIONAL CHANGE OF THE SUPERFICIAL FEMORAL AND POPLITEAL ARTERIES USING 3-D RECONSTRUCTION

Authors:  Andrew J. Klein, M.D., John C. Messenger, M.D., James Chen, Ph.D., John D. Carroll, Ivan P. Casserly, M.D.

Division:  Cardiology

FEL111

DIET-INDUCED INSULIN RESISTANCE AND MYOCARDIAL ISCHEMIA IN PIGS

Authors:  Jenny K. Lee, Ya Xu, Li Lu, Clifford R. Greyson, and Gregory G. Schwartz

Division:  Cardiology

FEL112 

LEFT VENTRICULAR END DIASTOLIC PRESSURE IS A PREDICTOR OF SUBOPTIMAL MYOCARDIAL REPERFUSION IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION FOR ST-ELEVATION MYOCARDIAL INFARCTION

Authors:  SJ Haugen, Gregg W. Stone, Roxana Mehran, Alexandra J. Lansky, Mitch Krucoff, John Webb, David A. Cox, Bruce R. Brodie, JD Carroll, J Lindenfeld

Division:  Cardiology

FEL113

EFFECT OF WORK RATE ON MUSCLE STO2 KINETICS IN PERIPHERAL ARTERIAL DISEASE

Authors:  T.A. Bauer,T.J. Barstow, and W.R. Hiatt

Division:  Cardiology

FEL114 

VASOCONSTRICTOR CHARACTERIZATION OF SPHINGOSHINE-1-PHOSPHATE AND ITS ANALOGUE FTY720 IN THE NORMOTENSIVE AND HYPOXIA-INDUCED HYPERTENSIVE RAT PULMONARY CIRCULATION

Authors:  Noriyuki Homma, Michelle A. Beutz, Masatoshi Imamura, Masahiko Oka, Ivan F. McMurtry

Division:  CVP Research

FEL115

ISOLATION OF RNA FROM THYROTROPE CELLS RECOVERED FROM DISPERSED MOUSE PITUITARY GLANDS USING LASER CAPTURE MICRODISSECTION

Authors:  Angela Pierce, Laura Pike, Janet Klass, and William Wood

Division:  Endocrinology, Metabolism and Diabetes

FEL116

ESTROGEN-REGULATED GENES INVOLVED IN RESPONSE TO NEOADJUVANT ENDOCRINE THERAPY FOR BREAST CANCER

Authors:  Djuana M.E. Harvell, Jennifer K. Richer, Nicole Spoelstra, Meenakshi Singh, Anthony Elias, Kathryn B. Horwitz. 

Division:  Endocrinology, Metabolism and Diabetes

FEL117 

DIVERGENT EFFECTS OF WEIGHT LOSS AND MACRONUTRIENT COMPOSITION ON 24-HOUR LIPIDS WITH LOW-CARBOHYDRATE VS. HIGH-CARBOHYDRATE DIET

Authors:  Marybeth Allian-Sauer, MD; Warren H. Capell, MD, Julie P. Sutherland, MD, Pamela Wolfe, MS, Natalie Talley, RN, Teri L. Hernandez, RN, Holly R. Wyatt, MD, Samuel Klein, MD, MS, Gary Foster, PhD, James O. Hill, PhD, and Robert H. Eckel, MD

Division:  Endocrinology, Metabolism and Diabetes

FEL118

DIVERGENT IMPACT OF LDL AND OXIDIZED LDL ON CREB ACTIVATION AND DOWNREGULATION

Authors:  Jane EB Reusch, Catherine Gliwa, Jodean Gunther, Michelle Pedler, Tom McDonald, Kevin O'Brien, and Irene Schauer

Division:  Endocrinology, Metabolism and Diabetes

FEL119

SiRNA-MEDIATED CREB REDUCTION INCREASES FATTY ACID TOXICITY IN VASCULAR SMOOTH MUSCLE CELLS

Authors:  Irene Schauer and Jane Reusch

Division:  Endocrinology, Metabolism and Diabetes 

FEL120  

PATIENT OUTCOMES FOLLOWING MINOR PAPILLA ENDOTHERAPY (MPE) FOR PANCREAS DIVISUM (PD)

Authors:  Lyssa N. Chacko, Yang K. Chen, Raj J. Shah

Division:  Gastroenterology & Hepatology

FEL121

SURFACE CLEARANCE OF NEUTROPHILS AS A MECHANISM OF RESOLVING INFLAMMATION: ROLE OF RESOLUTION-PHASE LIPIDS AND CD55

Authors:  Campbell EL, Daniels D, Hamilton KE, Louis NL, Kong TQ, Arita M, Serhan CN and Colgan SP

Division:  Gastroenterology & Hepatology

FEL122

MODULATION OF ENDOTHELIAL ATP-SIGNALING BY HYPOXIA: FUNCTIONAL CONSEQUENCES OF HIF-1 DEPENDENT P2Y2 INDUCTION

 Authors:  Thomas Weismueller 1,2, Tobias Eckle 1, Marion Faigle 1, Andreas Robinson 3, Peter Rosenberger3, and Holger K. Eltzschig 2, Sean P. Colgan1 - 1Department of Medicine, Division of Gastroenterology; University of Colorado Denver , Denver, CO 80262, USA,  2Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Germany and 3Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA

Division:  Gastroenterology & Hepatology

INHIBITION OF MEK 1/2 DECREASES CYCLIN D1 EXPRESSION AND INDUCES G1 CELL CYCLE ARREST OF COLON CANCER CELLS INDEPENDENTLY OF CASPASE ACTIVATION

Authors:  Hanna Kraus, Scott Beard, Dennis J. Ahnen and Pamela L. Rice

Division:  Gastroenterology & Hepatology

FEL124 

GEFITINIB IN EGFR FISH POSITIVE/P-AKT POSITIVE AND/OR NEVER SMOKER  PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER (NSCLC): RESULTS OF THE ONCOBELL TRIAL

Authors:  Giovanna Finocchiaro, Federico Cappuzzo, Claudia Ligorio, Pasi Antero Janne, Luca Toschi, Elisa Rossi, PhDc, Elisabetta Magrini, PhDa, Stefania Bartolini, Fortunato Ciardiello, Lucio Crino, Marileila Varella-Garcia.

Division:  Medical Oncology

FEL125

A FIRST IN HUMAN DOSE-RANGING STUDY TO ASSESS THE PHARMACOKINETICS, PHARMACODYNAMICS, AND TOXICITIES OF THE MEK INHIBITOR, ARRY-142886 (AZD6244), IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES

Authors:  J Call, LQM Chow, SG Eckhardt, J Reid, J Molina, L Hanson, J Piens, S Hariharan, M Basche, L Gore, S Diab, C O’Bryant, S Grolnic, B Hippert, MP Doyle, L Maloney, G Gordon, S Brown, K Litwiler, G Poch, AA Adjei.  University of Colorado Cancer Center, Aurora, CO; Mayo Clinic, Rochester, MN; Array BioPharma, Boulder, CO.

Division:  Medical Oncology

FEL126

HGS-ETR1, AN ANTIBODY TARGETING TRAIL-R1, IN COMBINATION WITH PACLITAXEL AND CARBOPLATIN IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES. RESULTS OF A PHASE 1 AND PK STUDY

Authors:  S. Leong, L.Q. Chow, S.G. Eckhardt, D.L. Gustafson, C. O'Bryant, S. Hariharan, S. Diab, N.L. Fox, A. Corey, K. Padavic, M. Brown, R. B. Cohen

Division:  Medical Oncology

FEL127 

REPLICATION OF SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH A SUSCEPTIBILITY LOCUS (2Q35) FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Authors:  Adam L. Friedlander, Russel Bowler

Division:  Pulmonary Sciences and Critical Care Medicine, UCD / Department of Medicine, National Jewish Medical and Research Center

FEL128

THE ROLE OF PTEN IN NEOINTIMA FORMATION

Authors:  Seth Ferguson, Pete Simpson, Nihal Kaplan-Albequerque, Raphael A. Nemenoff, and Mary C.M. Weiser-Evans

Division:  Renal Diseases & Hypertension

FEL129

NaPi IIc IS PRESENT IN MICRODOMAINS OF THE RENAL PROXIMAL TUBULAR BRUSH BORDER MEMBRANES

Authors:  Hideaki Takahashi, Maria Fuller, Hiroko Segawa, Ken-ichi Miyamoto, Jay Unruh, Enrico Gratton, Judith T Blaine, Sophia Y Breusegem, Nicholas P Barry, Moshe Levi

Division:  Renal Diseases & Hypertension

FEL130

RHEUMATOID ARTHRITIS (RA)-SPECIFIC AUTOANTIBODIES ARE PRESENT IN PATIENTS WITH INTERSTITIAL LUNG DISEASE (ILD) IN THE ABSENCE OF ARTHRITIS

Authors:  Alison M. Gizinski1, Dolly Kervitsky2, Richard Meehan2, Kevin K. Brown2, V. Michael Holers1, Kevin Deane1. 1University of Colorado Denver Health and Sciences Center, Denver, CO; 2National Jewish Medical and Research Center, Denver, CO

Division:  Rheumatology

FEL131

PATHOGENIC NATURAL IgM ANTIBODIES THAT RECOGNIZE PHOSPHOLIPIDS OR THE LIPID-BINDING PROTEIN ANNEXIN IV CAUSE INTESTINAL ISCHEMIA-REPERFUSION INJURY IN RAG1-/- MICE

Authors:  L. Kulik, S. D. Fleming, C. Moratz, G. C. Tsokos, V. M. Holers
Division:  Rheumatology

PRA101

Bcl-2 HOMOLOGY-3 (BH3)-ONLY PROTEIN EXPRESSION PROFILING IN AN IN VITRO MODEL OF PARKINSON’S DISEASE

Authors:  Emily K. Schroeder1, Kristen R. Ryan1, F. Alexandra Loucks1, Ron J. Bouchard1, and Daniel A. Linseman1,2,3
1Veterans Affairs Medical Center, Denver, CO, USA
2Neuroscience Program and 3Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado Denver, Denver, CO, USA

Division:  Clinical Pharmacology & Toxicology

PRA102

PATTERNS OF AMPLIFICATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) GENE IN NON-SMALL CELL LUNG CANCER (NSCLC)

Authors:  Margaret Skokan, Sujatha Gajapathy, Ana Carolina Xavier, Yun Xiao, Wilbur Franklin, Fred Hirsch, Marileila Varella Garcia

Division:  Cytogenetics Core

PRA103

HYPERINSULINEMIA AND ANGIOTNENSIN-II STIMULATE INCREASES IN ICAM-1 AND VCAM-1 PROTEIN EXPRESSION IN VASCULAR ENDOTHELIAL CELLS

Authors:  Hillary Akana and Marc Lee Goalstone, Ph.D.

Division:  Endocrinology, Metabolism and Diabetes

PRA104

FAMILY HEALTH PROMOTION PROJECT: PROMOTING COLON CANCER SCREENING IN HIGH RISK FAMILIES

Authors:  Meg Rebull, BA; Dennis Ahnen, MD, PI; Al Marcus, PhD; Jan Lowery, PhD; Meghan Hobein, MPH; and Karen Franklin, MA

Division:  Gastroenterology & Hepatology

PRA105

THE COMBINATION OF BORTEZOMIB AND SAHA INDUCES A SYNERGISTIC APOPTOTIC RESPONSE IN COLORECTAL CELL LINES IN VITRO

Authors:  Todd M Pitts, Mark Morrow, Owen Lockerbie, S. Gail Eckhardt

Division:  Medical Oncology

PRA106

DESIGNING FISH PROBES TO MAP TRANSLOCATION BREAKPOINTS AT GENOMIC LEVEL AND SCREEN INTERPHASE CELLS

Authors:  Yun Xiao, Wei Guo, Margaret Skokan, Sujatha Gajapathy, John Reeves, Hong Wu, Marileila Varella Garcia

Division:  Medical Oncology

RA101

MULTIPLE PRO-DEATH STIMULI ELICIT CASPASE-DEPENDENT OR CASPASE-INDEPENDENT CLEAVAGE OF THE MITOCHONDRIAL GTPASE OPA1 IN NEURONS

Authors:  F. Alexandra Loucks(1), Kristen R. Ryan(1), Shea Hilger(2), Angela K. Zimmermann(3), Ron J. Bouchard(1), Jay L. Brewster(2), and Daniel A. Linseman(1,3,4)

(1)Veterans Affairs Medical Center, Denver, Colorado, USA

(2)Natural Science Division, Pepperdine University, Malibu, California, USA
(3)Neuroscience Program and (4) Clinical Pharmacology & Toxicology, University of Colorado Denver

Division:  Clinical Pharmacology & Toxicology

SRPRA101

ESTABLISHMENT OF TTT-97 THYROTROPE CELLS IN CULTURES

Authors:  Klass, Janet E., Kerr, Janice M., Mitchell, Jeffrey R., Woodmansee, Whitney W., Pike, Laura A., Ridgway, E. Chester, and Wood, William M.

Division:  Endocrinology, Metabolism and Diabetes

SRPRA102

EPIDERMAL GROWTH FACTOR SUBSTRATE 8 (EPS8) IS UPREGULATED AND SPROUTY 4 (SPRY4) IS DOWNREGULATED IN HUMAN PITUITARY TUMORS:  A MODE OF GROWTH FACTOR AMPLIFICATION?

Authors:  M Xu, L Cary, S Ronnekiev-Kelly, BK DeMasters, K Lillehei, S Nielsen-Preiss, ME Wierman

Division:  Endocrinology, Metabolism and Diabetes

SRPRA103

TESTOSTERONE SUPPLEMENTATION AND OBSTRUCTIVE SLEEP APNEA IN HEALTHY HYPOGONADAL OLDER MEN

Authors:  Nakamura, T., MA; R. Ballard, MD; P. Heyn, PhD; Y. Schmidt, BA; and RSS Schwartz, MD.

Division:  Geriatrics

JR101

IDENTIFICATION OF NF-kB MODIFICATIONS GENERATED BY CIGARETTE SMOKE ALDEHYDES

Authors:  Cherie Lambert, JiMei Li, Mary Portas, Megan Quintana and Brian M. Freed

Division:  Allergy & Clinical Immunology

JR102

CIGARETTE SMOKING MODULATES T CELL RESPONSES IN LUNG AND MESENTERIC LYMPH NODES

Authors:  Ashley A. Frazer-Abel, Sabine Lazis, Jean Harvey, and Brian M. Freed.

Division:  Allergy & Clinical Immunology

JR103

FUNCTIONAL AND PHENOTYPIC CHARACTERIZATOIN OF CD57+ CD4+ T CELLS AND THEIR ASSOCIATION WITH CHRONIC BERYLLIUM DISEASE

Authors:  Brent E. Palmer, Doug Mack, Allison Martin, and Andrew P. Fontenot

Division:  Allergy & Clinical Immunology

JR104

PD-1 EXPRESSION ON HIV-SPECIFIC CD4+ T CELLS IS DRIVEN BY HIV REPLICATION AND IS ASSOCIATED WITH T CELL DYSFUNCTION

Authors:  Michelle D'Souza, Andrew Fontenot, Doug Mack, Stephanie Dillon, Amie Meditz, Cara Wilson, Elizabeth Connick and Brent Palmer

Division:  Allergy & Clinical Immunology

JR105

A GENOMICS APPROACH TO GENDER-SPECIFIC DIFFERENCES IN AUTOIMMUNITY

Authors:  Trine N. Jorgensen, John Kappler, Philippa Marrack

Division:  Allergy & Clinical Immunology

JR106

THE DITHIOL ANTIOXIDANT, BUCILLAMINE, PROTECTS AGAINST CARDIAC DYSFUNCTION AND REMODELING IN A MURINE MODEL OF MYOCARDIAL ISCHEMIA-REPERFUSION INJURY

Authors:  S. Kelly Ambler, Yvonne K Hodges, Gayle M. Jones, Carlin S. Long, and Lawrence D. Horwitz

Division:  Cardiology

JR107

YY1 PROTECTS AGAINST PATHOLOGIC CARDIAC HYPERTROPHY THROUGH A INTERACTION WITH HDAC5

Authors:  Carmen Sucharov, PhD; Karen Dockstader, Karin Nunley, Michael Bristow, MD PhD

Division:  Cardiology

JR108

TARGETED DISRUPTION OF THE MURINE MEKK2 GENE PREVENTS HYPOXIA-INDUCED RIGHT VENTRICULAR HYPERTROPHY

Authors:  R. Dale Brown, S. Kelly Ambler, Gary L. Johnson, Carlin S. Long, Timothy P. Garrington

Division:  Cardiology

JR109

CYTOKINES REGULATE MATRIX METALLOPROTEINASE EXPRESSION AND CELL MIGRATION IN RAT CARDIAC FIBROBLASTS

Authors:  R. Dale Brown, Gayle M. Jones, Paul Hudson, Rebecca E. Laird, M. Darren Mitchell, Carlin S. Long

Division:  Cardiology

JR110

MUTATIONS IN THE GENE ENCODING THE DESMOSOMAL PROTEIN PLAKOPHILIN-2 CAUSE ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA/CARDIOMYOPATHY

Authors:  Carl V Barnes, Francesca Brun, Matthew RG Taylor, Xiao Zhu, Dobromir Slavov, Bruno Pinamonti, Gianfranco Sinagra, Luisa Mestroni

Division:  Cardiology

JR111

IDENTIFICATION OF A SILENT MUTATION THAT PERTURBS LMNA GENE SPLICING AND CAUSES DILATED CARDIOMYOPATHY

Authors:  Matthew R.G. Taylor, Elaine B. Spector, Dobromir Slavov, Luisa Mestroni, Familial Cardiomyopathy Registry

Division:  Cardiology

JR112

GFP KNOCKED INTO THE DOPAMINE TRANSPORTER LOCUS OF EMBRYONIC STEM CELLS LEADS TO GFP-LABELED DOPAMINE NEURONS GENERATED IN TISSUE CULTURE AND IN VENTRAL MESENCEPHALON OF KNOCK-IN MICE

Authors:  Wenbo Zhou, PhD and Curt R. Freed, MD

Division:  Clinical Pharmacology & Toxicology

JR113

HYPEROXIC EXPOSURE DECREASES PULMONARY MICROVASCULAR DENSITY, RESIDENT ENDOTHELIAL PROGENITOR POPULATIONS AND DELAYS BONE MARROW-DERIVED ENDOTHELIAL PRECURSOR MOBILIZATION IN A MURINE MODEL OF BRONCHOPULMONARY DYSPLASIA

Authors:  S. Majka, D. Irwin, K. Helm, M. Imamura, K. Fagan, J. Harral, K.A. Young, D. Klemm, E.C. Dempsey &  J. West

Division:  CVP Research

JR114

RHO KINASE-MEDIATED VASOCONSTRICTION IS IMPORTANT IN SEVERE OCCLUSIVE PULMONARY ARTERIAL HYPERTENSION IN RATS

Authors:  Masahiko Oka, Noriyuki Homma, Laimute Taraseviciene-Stewart, Kenneth G. Morris, Donatas Kraskauskas, Norbert F. Voelkel, Ivan F. McMurtry

Division:  CVP Research

JR115

SPONTANEOUS FUSION WITH, AND TRANSFORMATION OF HOST MOUSE STROMA BY, MALIGNANT HUMAN BREAST CANCER EPITHELIUM: “CANCER WITHIN A CANCER”

Authors:  Britta M. Jacobsen, J. Chuck Harrell, Paul Jedlicka, Virginia F. Borges, Marileila Varella-Garcia and Kathryn B. Horwitz

Division:  Endocrinology, Metabolism and Diabetes

JR116

LACTOTROPH-TARGETED EXPRESSION OF A DOMINANT-NEGATIVE ETS RESULTS IN DECREASED LACTOTROPH CELL NUMBER AND SERUM PROLACTIN LEVELS IN TRANSGENIC MICE

Authors:  John J Tentler and Arthur Gutierrez-Hartmann

Division:  Endocrinology, Metabolism and Diabetes

JR117

EFFECT OF THYROID HORMONE ON TALPHAT1 THYROTROPIC CELLS

Authors:  Virginia D. Sarapura, Janice M. Kerr, Jeffrey R. Mitchell, Janet E. Klass, William M. Wood and E. Chester Ridgway

Division:  Endocrinology, Metabolism and Diabetes

JR118

RESTORATION OF CREB FUNCTION IS LINKED TO COMPLETION AND STABILIZATION OF ADAPTIVE CARDIAC HYPERTROPHY IN RESPONSE TO EXERCISE

Authors:  Peter A, Watson, Jane E-B. Reusch, Sylvia A. McCune, Leslie A. Leinwand, Stephen W. Luckey, John P. Konhilas, David A. Brown, Adam J. Chicco, Carlin S. Long, and Russell L. Moore

Division:  Endocrinology, Metabolism and Diabetes

JR119

NOVEL CYTOPROTECTIVE ACTIONS OF CURCUMINOIDS IN PANCREATIC BETA CELLS

Authors:  Subbiah Pugazhenthi, Leonid Akhov, Gopalan Selvaraj, Sunil George, A.N. Balamurugan, Jane Reusch, Alexander Wiseman, Ron Gill and John Hutton

Division:  Endocrinology, Metabolism and Diabetes

JR120

IDENTIFYING ALTERED GENE EXPRESSION IN NEUROBLASTOMA CELLS PRECEDING APOPTOSIS

Authors:  Piruz Nahreini, Xiang-Dong Yan, Cynthia P. Andreatta, Kedar N. Prasad, and Neil W. Toribara

Division:  Gastroenterology & Hepatology

JR121

EARLY AND SUSTAINED ACTIVATION OF CD56POS NATURAL T (NT) CELLS IS ASSOCIATED WITH RESOLUTION OF ACUTE HEPATITIS C VIRAL (HCV) INFECTION

Authors:  Lucy Golden-Mason, Nicole Castelblanco, Cliona O’Farrelly, Hugo R. Rosen

Division:  Gastroenterology & Hepatology

JR122

LOSS OF INTERLEUKIN-7 RECEPTOR ALPHA CHAIN (CD127) EXPRESSION IN ACUTE HCV INFECTION ASSOCIATED WITH VIRAL PERSISTENCE

Authors:  Lucy Golden-Mason, James R. Burton Jr, Nicole Castelblanco, Jared Klarquist, Salvador Benlloch, Chia Wang and Hugo R. Rosen.

Division:  Gastroenterology & Hepatology

JR123

CXCR2 LIGANDS IN ADPKD LIVER CYST FLUIDS CAN PROMOTE CYST GROWTH

Authors:  Claudia R. Amura*1, Berenice Gitomer†1, Kelley Brodsky*,  Alkesh Jani†, Robert Schrier†, and R. Brian Doctor* - Division of Gastroenterology and Hepathology*, and Division of Renal Diseases and Hypertension†, Department of Medicine, University of Colorado Denver and Health Sciences, Denver, CO - 1joint-first authors

Division:  Gastroenterology & Hepatology

JR124

VEGF SIGNALING PROMOTES LIVER CYST GROWTH IN PKD2(WS25/-) MICE

Authors:  Claudia R. Amura, Kelley Brodsky, Rachel Groff, Norbert Voelkel, R. Brian Doctor

Division:  Gastroenterology & Hepatology

JR125

ALTERED HEPATIC METABOLIC FUNCTION IN PATIENTS WITH CHRONIC HEPATITIS C IS ASSOCIATED WITH OBESITY, INSULIN RESISTANCE, OR HEPATIC STEATOSIS, INDEPENDENT OF CIRRHOSIS:  RESULTS FROM THE HALT-C TRIAL

Authors:  Gregory T. Everson, Clark C. Kulig, Mitchell L. Shiffman, Richard Sterling, John C. Hoefs, Timothy Morgan, Teresa Curto, James E. Everhart.  David Wagner, QLFT study group

Division:  Gastroenterology & Hepatology

JR126

EFFECT OF A MAILED BROCHURE TO INCREASE ADHERENCE TO SCREENING COLONOSCOPY: AN RCT

Authors:  Thomas D. Denberg, MD, PhD, John M. Coombes, MD, Tim E. Byers, MD, MPH, Alfred C. Marcus, PhD, Lawrence E. Feinberg, MD, John F. Steiner, MD, MPH, Dennis J. Ahnen, MD

Division:  General Internal Medicine

JR127

THE INFLUENCE OF PATIENT RACE AND SOCIAL VULNERABILITY ON UROLOGIST TREATMENT RECOMMENDATIONS IN LOCALIZED PROSTATE CARCINOMA

Authors:  Thomas D. Denberg, MD, PhD, Fernando J. Kim, MD, Robert C. Flanigan, MD, Diane Fairclugh, DrPH, Brenda L. Beaty, MSPH, John F. Steiner, MD, MPH, Richard M. Hoffman, MD, MPH

Division:  General Internal Medicine

JR128

SPIRITUAL WELL-BEING AND DEPRESSION IN HEART FAILURE

Authors:  David B Bekelman MD, MPH; Sydney M Dy MD, MSc; Diane M Becker ScD, MPH; Ilan S Wittstein MD, Danetta E Hendricks MA, Traci E Yamashita MS, Sheldon H Gottlieb MD

Division:  General Internal Medicine

JR129

IMAGINED VOICES: AN EXERCISE IN EMPATHY

Authors:  Anjali Dhurandhar, MD; Joshua Hauser, MD; Douglas Reifler, MD

Division:  General Internal Medicine

JR130

SYSTEMIC LUPUS ERYTHEMATOSIS PRESENTING WITH DILATED CARDIOMYOPATHY

Authors:  Tony J. Toloczko and Gregory J. Misky

Division:  General Internal Medicine

JR131

HYPERCOAGULABLE STATE AS PRIMARY PRESENTATION OF OCCULT MALIGNANCY

Authors:  Gregory J. Misky, M.D., Stephen Murphy, M.D.

Division:  General Internal Medicine

JR132

A NOVEL INTERNAL MEDICINE RESIDENCY HOSPITALIST TRAINING PROGRAM

Authors:  J.J. GLASHEEN1; A. TROSTERMAN1; M. HARRIS1; J.M. YOUNGWERTH1; E.C. CHU1; M. REID1. 1University of Colorado Denver, Denver, CO.

Division:  General Internal Medicine

JR133

THE EFFECT OF AN INTENSIVE PALLIATIVE CARE-FOCUSED RETREAT ON HOSPITALIST FACULTY AND RESIDENT PALLIATIVE CARE KNOWLEDGE AND COMFORT/CONFIDENCE

Authors:  Glasheen JJ, Youngwerth JM, Johnson DC, University of Colorado Denver

Division:  General Internal Medicine

JR134

COMPUTERIZED COGNITIVE TEST PERFORMANCE IN COMPUTER USER AND NON-USER OLDER ADULTS

Authors:  Patricia C. Heyn, PhD, Tammie Nakamura., MS, Rosa A. Tang, MD, MPH

Division:  Geriatrics

JR135

COMPARISON OF CASE MIX CHARACTERISTICS OF POST-ACUTE VS. CHRONIC CARE HOME HEALTH PATIENTS

Authors:  Eugene J. Nuccio, Ph.D., David F. Hittle, Ph.D.

Division:  Health Care Policy & Research

JR136

CONTINUED DECLINES IN MORTALITY AND HOSPITALIZATION DURING THE 10-YEAR ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV+ PATIENTS RECEIVING CARE AT A UNIVERSITY-BASED CLINICAL PROGRAM

Authors:  John R. Koeppe, M.D., Lorri G. Ogden, Ph.D., Steven C. Johnson, M.D.

Division:  Infectious Diseases

JR137

CULTURE VS. BROAD-RANGE MOLECULAR DETECTION OF MICROBES IN ENDOSCOPIC SPECIMENS FROM ADULTS WITH CHRONIC SINUSITIS AND CONTROLS: A PILOT PROJECT.

Authors:  M. A. De Groote, S. Bozell, R. Katial, R. Alam, D.N. Frank, J.K. Harris, N.R. Pace, R. J. Harbeck and T. Kingdom

Division:  Infectious Diseases

JR138

CCR5 AND CXCR4 ARE HIGHLY EXPRESSED ON LYMPH NODE FOLLICULAR (CD57+) CD4+ T CELLS

Authors:  A. Meditz, J. Folkvord, M. McCarter, E. Connick

Division:  Infectious Diseases

JR139

IS THERE SEX DISCRIMINATION IN AIDS-ASSOCIATED KAPOSI’S SARCOMA?

Authors:  Amie L. Meditz, Margaret Borok, Samantha MaWhinney, Ivy Gudza, Buxton Ndemera, Lovemore Gwanzura and Thomas B. Campbell

Division:  Infectious Diseases

JR140

SILIBININ SYNERGIZES WITH MITOXANTRONE TO DECREASE CELL VIABILITY IN PROSTATE CANCER CELLS

Authors:  T. W. Flaig, L. Su, G. Harrison, R. Agarwal, L. M. Glode; University of Colorado Denver, Aurora, CO; University of Colorado Denver, Denver, CO

Division:  Medical Oncology

JR141

A PHASE I DOSE-ESCALATION STUDY OF WEEKLY IMC-1121B, AN IgG1 FULLY HUMAN ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 MONOCLONAL ANTIBODY, IN PATIENTS WITH ADVANCED CANCER

Authors:  Camidge DR, Eckhardt SG, Diab S, Gore L, Chow L, O’Bryant C, Temmer E, Fox F, Youssoufian H, Cohen RB

Division:  Medical Oncology

JR142

A DOSE-RANGING STUDY OF THE TOXICITIES, PHARMACOLOGICAL, AND BIOLOGICAL EFFECTS OF THE SELECTIVE APOPTOTIC ANTINEOPLASTIC DRUG (SAAND), OSI-461, IN PATIENTS WITH ADVANCED CANCER, IN THE FASTING AND FED STATE

Authors:  CH Lieu, S Leong, M Basche, L Gore, K Leonardi, MK Schultz, S Hariharan, L Chow, S Diab, A Gibbs, R Boinpally, SG Eckhardt, CL O’Bryant

Division:  Medical Oncology

JR143

TOLL/IL-1R DOMAIN-CONTAINING ADAPTOR PROTEIN (TIRAP) IS A CRITICAL MEDIATOR OF ANTIBACTERIAL DEFENSE IN THE LUNG AGAINST KLEBSIELLA PNEUMONIAE BUT NOT PSEUDOMONAS AERUGINOSA.

Authors:  Jeyaseelan S, Young SK, Yamamoto M, Arndt PG, Akira S, Kolls JK, Worthen GS.

Division:  Pulmonary Sciences and Critical Care

JR144

REGULATORY ROLE OF γδ T CELLS IN THE RECRUITMENT OF CD4+ AND CD8+ T CELLS TO LUNG AND SUBSEQUENT PULMONARY FIBROSIS

Authors:  Philip L. Simonian, MD, Christina L. Roark, PhD, Rebecca L. O’Brien, PhD, Andrew P. Fontenot, MD

Division:  Pulmonary Sciences and Critical Care

JR145

APPLICATIONS OF MICROARRAY TECHNOLOGY IN BIOMEDICAL RESEARCH-INTRODUCTION OF MICROARRAY CORE LAB @ UCD

Authors:  Bifeng Gao, Mark Geraci

Division:  Pulmonary Sciences and Critical Care

JR146

ACUTE RENAL FAILURE (ARF)-MEDIATED LUNG INJURY AFTER BILATERAL NEPHRECTOMY

Authors:  Thomas Hoke, Ivor Douglas, Zhibin He, Wenfeng Fang, Christina Klein, Norbert Voelkel, Charles Edelstein, Sarah Faubel

Division:  Renal Diseases & Hypertension

JR147

TRAFFICKING OF THE SODIUM PHOSPHATE CO-TRANSPORTER IN BRUSH BORDER MICROVILLI AND ROLE OF THE ACTIN CYTOSKELETON

Authors:  Nicholas Barry, Judith Blaine, Sophia Breusegem, Hideaki Takahashi, Moshe Levi

Division:  Renal Diseases & Hypertension

JR148

PROTECTIVE ROLE OF FXR ACTIVATION IN DIABETIC NEPHROPATHY

Authors:  Tao Jiang, MD, PhD, Xiaoxin Wang, PhD, Gregory Proctor, MD, Hideaki Takahashi, MD and Moshe Levi, MD

Division:  Renal Diseases & Hypertension

JR149

REGULATION OF RENAL FATTY ACID AND CHOLESTEROL METABOLISM, INFLAMMATION, AND FIBROSIS IN AKITA AND OVE26 MICE WITH TYPE 1 DIABETES

Authors:  Moshe Levi, MD, Gregory Proctor, MD, Jinping Li, MD, PhD, Xiaoxin Wang, PhD, and Tao Jiang, MD,PhD

Division:  Renal Diseases & Hypertension

JR150

DISRUPTION OF VASCULAR CALCIFICATION BY PPAR GAMMA

Authors:  Yolanda E. Bogaert, Jane Reusch and Raphael Nemenoff

Division:  Renal Diseases & Hypertension

JR151

PI-3K DEPENDENT ALTERATION IN VASCULAR SMOOTH MUSCLE CELL (VSMC) FUNCTION IN PI-3K DEPENDENT ALTERATION IN VASCULAR SMOOTH MUSCLE CELL (VSMC) FUNCTION IN RESPONSE TO TYPE 1 COLLAGEN

Authors:  Yolanda Bogaert, Jody Grippa, Kevin O'Brien, Raphael Nemenoff and Jane Reusch

Division:  Renal Diseases & Hypertension

JR152

SPECIFIC CYTOKINE AND CHEMOKINE INCREASES PRECEDE THE APPEARANCE OF ANTI-CYCLIC CITRULLINATED PROTEIN (ANTI-CCP) ANTIBODIES AND RHEUMATOID FACTOR (RF) IN THE PRE-CLINICAL PERIOD OF RHEUMATOID ARTHRITIS (RA) DEVELOPMENT

Authors:  Kevin D. Deane1, Wolfgang Hueber2, Darcy S. Majka3, Beren H. Tomooka2, William R. Gilliland4, Lezlie A. Parrish1, Mark C. Parish1, Jill M. Norris1, William H. Robinson5, V. Michael Holers1. 1University of Colorado, Denver, CO; 2Stanford University, Palo Alto, CA; 3Northwestern University, Chicago, IL; 4Walter Reed Army Medical Center, Washington, DC; 5Stanford University/Palo Alto Veteran's Administration Hospital, Palo Alto, CA

Division:  Rheumatology

JR153

PROBABLE RA AS DEFINED BY THE CONNECTIVE TISSUE DISEASE SCREENING QUESTIONNAIRE IS ASSOCIATED WITH RHEUMATOID FACTOR IN A POPULATION AT-RISK FOR RA THAT IS ENRICHED FOR DR4 AND/OR FIRST-DEGREE RELATIVE STATUS

Authors:  Darcy S. Majka1, Kevin D. Deane2, Lezlie A. Parrish2, Elizabeth W. Karlson3, Elizabeth D. Ferucci4, Marian Rewers2, Jill M. Norris2, V. Michael Holers2. 1Northwestern University, FSM, Chicago, IL; 2University of Colorado Denver, Denver, CO; 3Harvard Medical School, Boston, MA; 4Alaska Native Tribal Health Consortium, Anchorage, AK

Division:  Rheumatology

JR154

CHARACTERIZATION OF SOLUTION STRUCTURE OF HUMAN COMPLEMENT RECEPTOR TYPE 2 (CR2/CD21) AND DNA INTERACTIONS: IMPLICATIONS FOR ITS ROLES IN THE IMMUNE RESPONSE AND THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Authors:  R. Asokana, T. Lyubchenkoa, G. Szakonyib, J.M. Thurmana, S.A. Boacklea, X. S. Chenc and V. M. Holersa
aDepartments of Medicine and Immunology, University of Colorado Denver, Denver, CO 80262, USA.
bInstitute of Membrane and Systems biology, University of Leeds, Leeds, LS2 9JT, UK.
cMolecular and Computational Biology, University of Southern California Los Angeles, Los Angeles, CA 90089, USA.

Division:  Rheumatology

JR155

HISTOPATHOLOGIC PATTERNS AND SURVIVAL IN SYSTEMIC SCLEROSIS (SSC) – INTERSTITIAL LUNG DISEASE (ILD) COMPARED WITH IDIOPATHIC INTERSTITIAL PNEUMONIA (IIP)

Authors:  Aryeh Fischer, Steve D Groshong, Carlyne Cool, Douglas Curran-Everett, Jeffrey J Swigris, Stephen K Frankel, Gregory P Cosgrove, Richard T Meehan, and Kevin K Brown

Division:  Rheumatology

SR101

Ara h 2.02 IS A MORE POTENT CROSS-LINKER OF ANTI- PEANUT IgE THAN IS Ara h 2.01

Authors:  R El Mezayen MD PhD, L Pons PhD, M West PhD, S Stanley PhD, AW Burks MD, M El Gazzar MD,  Mark W. Duncan PhD, Kirk C. Hansen PhD, and SC Dreskin MD

Division:  Allergy & Clinical Immunology

SR102

EFFECTS OF HIGH-DOSE ATORVASTATIN IN PATIENTS >65 YEARS WITH ACUTE CORONARY SYNDROME: AN ANALYSIS FROM THE MYOCARDIAL ISCHEMIA REDUCTION WITH AGGRESSIVE CHOLESTEROL LOWERING (MIRACL) STUDY

Authors:  Anders G. Olsson, Gregory G. Schwartz, Michael Szarek, Don Luo, Michael J Jamieson

Division:  Cardiology

SR103

AN INTERACTIVE COMPUTERIZED CARDIOVASCULAR RISK MODULE HIGHLIGHTS MISPERCEPTIONS AND UNDER-TREATMENT OF RISK FACTORS AMONG HEALTH FAIR PARTICIPANTS

Authors:  Stephanie M. Coronel MPH CHES1, Thomas D. MacKenzie MD MSPH, Becki Bucher Bartelson PhD, Bonnie Leeman-Castillo PhD, Lisa Jensen BSN RN, Craig Kapral MA, Cindy Belz RN NP MBA, Raymond Estacio MD, Mori Krantz, MD

Division:  Cardiology

SR104

ROLE OF ANGIOTENSIN RECEPTORS ON OXIDATIVE STRESS IN DOPAMINERGIC CELLS

Authors:  Susan M. Jones, David Cantu, Angela Rachubinski, Jason White, Tom Grammatopoulos, Andy Poczobutt, Gregg Banninger, Mita Das, Michael Zawada

Division:  Clinical Pharmacology & Toxicology

SR105

REGULATION OF ERK5 BY INSULIN AND ANGIOTENSIN-II IN VASCULAR SMOOTH MUSCLE CELLS

Authors:  Girish Sharma, Ph.D and Marc Lee Goalstone, Ph.D.

Division:  Endocrinology, Metabolism and Diabetes

SR106

IDENTIFICATION OF MOLECULAR ANTI-INFLAMMATORY MECHANISMS OF ADENOSINE: CULLIN-1 DENEDDYLATION DURING HYPOXIC PRECONDITIONING

Authors:  Joseph Khoury, Juan C. Ibla, Sean P. Colgan

Division:  Gastroenterology & Hepatology

SR107

HOMEOSTATIC CONTROL OF TYPE I INTERFERON BY ADENOSINE: IMPLICATIONS IN MURINE COLITIS

Authors:  Nancy A. Louis, Andreas M. Robinson, Jörn Karhausen, Melanie Scully, Sean P. Colgan

Division:  Gastroenterology & Hepatology

SR108

MUCOSAL PROTECTION BY HIF PROLYL HYDROXYLASE INHIBITION

Authors:  Andreas Robinson, Jörn Karhausen, Sean P.Colgan

Division:  Gastroenterology & Hepatology

SR109

HIF-DEPENDENT INDUCTION OF ADENOSINE A2B RECEPTORS IN HYPOXIA

Authors:  Tianqing Kong, Karen A. Westerman, Marion Faigle, Holger K. Eltzschig, Sean P. Colgan

Division:  Gastroenterology & Hepatology

SR110

BENZO[A]PYRENE EXPOSURE OF HUMAN HEPATOMA CELLS EXPRESSING THE HCV SUBGENOMIC REPLICON CAUSES DNA DAMAGE

Authors:  Linda C. Quattrochi, Garret R. Anderson, and Mieko Iwahashi

Division:  Gastroenterology & Hepatology

SR111

TRENDS IN ANTICOAGULATION FOR ATRIA FIBRILLATION IN THE UNITED STATES

Authors:  Shane B. Rowan, Desiree N. Bailey, Caroline Emsermann Bublitz and Robert J. Anderson

Division:  General Internal Medicine

SR112

MYOCARDIAL PERFUSION INDEX IS INVERSELY CORRELATED TO PULMONARY CAPILLARY WEDGE PRESSURE DURING EXERCISE IN TYPE 2 DIABETES

Authors:  M.Y. Chen, R.A. Quaife, E.E. Wolfel, B.M. Groves, T. Miller, J.G. Regensteiner

Division:  General Internal Medicine

SR113

ANEMIA IN CENTENARIANS IS ASSOCIATED WITH ELEVATED SERUM 2-METHYLCITRIC ACID BUT NOT OTHER MEASURES OF COBALAMIN DEFICIENCY OR RENAL STATUS

Authors:  Sally P. Stabler*, Robert H. Allen*, Mary Ann Johnson, Dorothy B. Hausman, Adam Davey, Leonard W. Poon. *Department of Medicine, University of Colorado Denver and Department of Foods and Nutrition, University of Georgia

Division:  Hematology

SR114

THE TRC8 HEREDITARY KIDNEY CANCER GENE IS A STEROL-REGULATED E3 UBIQUITIN LIGASE LINKING LIPID STATUS WITH GROWTH CONTROL, PROTEIN TRANSLATION AND HYPOXIA

Authors:  Jason P. Lee1, Harry A. Drabkin1, Anne Brauweiler1, Luciano Costa1, Dan Chan1, Sierra McNamara1, Joan Hooper5, Kevin Lorick2, Yienche Tsai2, Ming Zhou3, Michael C. Rudolph4, Ronald Bukowski3, Allan M. Weissman2 and Robert M. Gemmill1

Division:  Medical Oncology

SR115

CHROMOSOMAL ANEUSOMY IN SPUTUM PREDICTS FOR LUNG CANCER IN NESTED CASE-CONTROL STUDY

Authors:  Marileila Varella-Garcia, Chan Zeng, Holly J. Wolf, Xiang Yin, Fred R. Hirsch, Tim Byers, Tim Kennedy, York E. Miller, Anna E. Barón, Wilbur A. Franklin

Division:  Medical Oncology

SR116

MicroRNA EXPRESSION IN MELANOMA

Authors:  Philip Weston, Diane Birks, Pilar Londano, Amy McGranahan, Rose Montoya, Sammie Lamont Moss, Willard Peng, Jacinta Schrauenagel, Adetokunbo Taiwo, Hung Tran, Reginald Trevino, William Robinson, and Lynne Bemis

Division:  Medical Oncology

SR117

PROTEIN KINASE Cβ INHIBITOR FOR LUNG CANCER THERAPY

Authors:  Zhiyong Zhang, MD, Di Zheng, MD, Alexandra Dulude, Victor Chen, and Doreen Ma, PhD, Paul A Bunn, Jr, MD and Daniel Chan, PhD.

Division:  Medical Oncology

SR118

SAFETY AND EFFICACY OF COMBINATION THERAPY WITH SILDENAFIL AND EPOPROSTENOL IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION (PA

Authors:  G Simonneau1, G Burgess2, L Collings2, RJ Barst3, N Galiè4, LJ Rubin5, DB Badesch6 - 1Hôpitaux Antoine-Beclere, Paris, France; 2Pfizer Ltd, Sandwich, England; 3Columbia University, New York, US;4University of Bologna, Bologna, Italy; 5UCSD, San Diego, US; and 6University of Colorado Denver, Denver, US.

Division:  Pulmonary Sciences and Critical Care

SR119

M-CUBED: MENTOR-MENTEE-MATCHING

Authors:  Dr. Laurie Shroyer, Joe Huggins, Michelle Smith

Division:  Pulmonary Sciences and Critical Care

SR120

PATHWAYS OF APOPTOSIS IN CASPASE-3 GENE DEFICIENT CPK/CPK MICE WITH POLYCYSTIC KIDNEY DISEASE (PKD)

Authors:  Yunxia Tao, Iram Zafar, Zhibin He, Lawrence Lu, Robert W. Schrier, and Charles L. Edelstein

Division:  Renal Diseases & Hypertension