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Edward Melanson, Ph.D., FACSM, Associate Professor of Medicine

Dr. Melanson began his research career as a post-doctoral fellow in the Center for Human Nutrition in 1998, and received a faculty appointment in the Division in 2003. His research interests are the effects of diet, exercise, and obesity on substrate metabolism and energy expenditure. Currently, Dr. Melanson is performing studies on the effects of different intensities of exercise and manipulations in dietary fat on fat oxidation. These studies are performed using whole-room indirect calorimetry. He also is currently performing an exercise intervention aimed at determining the effects of exercise on the different components of energy expenditure, particularly non-resting energy expenditure. In these studies, a variety of approaches are used to assess energy expenditure including doubly labeled water, indirect calorimetry, and accelerometry. Dr. Melanson's research is funded by the NIH.

Dr. Melanson is an Assistant Director of the Energy Balance Core Lab. In this capacity, he oversees the operation of the whole-room calorimeter, located on the Clinical Translational Research Center (CTRC).

Selected Publications:

  • MacLean PS, Higgins JA, Jackman MR, Johnson GC, Fleming-Elder BK, Wyatt HR, Melanson EL , Hill JO. Related Articles, Links Peripheral metabolic responses to prolonged weight reduction that promote rapid, efficient regain in obesity-prone rats. Am J Physiol Regul Integr Comp Physiol. 2006 Jun;290(6):R1577-88.  PUBMED
     
  • Melanson, E.L ., W.T. Donahoo, F. Dong, T. Ida, and M.B. Zemel, Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res, 2005. 13(12): p. 2102-12. PUBMED
     
  • Melanson, E.L ., J.R. Knoll, M.B. Bell, W.T. Donahoo, J.O. Hill, L.J. Nysse, L. Lanningham-Foster, J.C. Peters, and J.A. Levine, Commercially-available pedometers: considerations for accurate step-counting. Prev med, 2004. 39(2): p. 361-368. PUBMED
     
  • Melanson, E.L ., T.A. Sharp, J. Schneider, W.T. Donahoo, G.K. Grunwald, and J.O. Hill, Relation between calcium intake and fat oxidation in adult humans. Int J Obes Relat Metab Disord, 2003  27(2): p. 196-203. PUBMED
     
  • Melanson, E.L ., T.A. Sharp, H.M. Seagle, T.J. Horton, W.T. Donahoo, G.K. Grunwald, J.T. Hamilton, and J.O. Hill, Effect of exercise intensity on 24-h energy expenditure and nutrient oxidation. J Appl Physiol, 2002. ...92(3): p. 1045-52. PUBMED
     
  • Levine, J., E.L. Melanson , K.R. Westerterp, and J.O. Hill, Measurement of the components of nonexercise activity thermogenesis. Am J Physiol Endocrinol Metab, 2001. 281(4): p. E670-5. PUBMED