Endocrinology

Sex Steroid Function and Breast Cancer

Sex steroids (endogenous androgens, estrogens, and progesterone) are produced primarily by the gonads and adrenal gland, but other tissues around the body are able to interconvert the various forms of these hormones in smaller amounts. Sex steroids are primarily involved in the development of sexual characteristics and reproduction, but receptors for these hormones are located in many tissues all around the body. It is clear they have a significant impact on energy balance, growth, body fat distribution, and fuel utilization. Researchers within the division have interests in the hypothalamic-pituitary-gonadal axis that controls the levels of these hormones and how this axis impacts tissue specific gene expression and whole body metabolism. In addition, a number of our researchers have a particular interest in how these hormones are involved in the development and progression of breast cancer.

Researchers in Endocrinology currently conducting sex steroid function and breast cancer related research:

Gutierrez-Hartmann, Harvell, Horwitz, Jacobsen, MacLean, McDermott, Perreault, Rothman, Sartorius, Schweppe, Wierman

Recent Publications Coming Soon!