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Faculty Profile

Holly Wyatt, M.D., Associate Professor of Medicine

Dr. Holly R. Wyatt is a physician and clinical researcher at The Center for Human Nutrition in Denver, Colorado. Research interests include studies aimed at understanding whether energy metabolism is altered in obese individuals and in individuals who are successfully maintaining weight loss (reduced-obese). Dr. Wyatt’s research interests also include measuring resting energy expenditure, fat oxidation, total energy expenditure and activity levels in the National Weight Control Registry’s (NWCR) long-term reduced population. Dr Wyatt also studies how diet composition affects long-term success in weight loss maintenance. She has studied subjects who are losing weight with the Atkins’ (low carbohydrate) vs. a low fat, high carbohydrate diet. She has also investigated diet composition, exercise patterns and breakfast consumption in the NWCR.

Dr. Wyatt received her MD degree from Baylor College of Medicine in Houston, Texas and completed both an internal medicine residency and an endocrinology and metabolism fellowship at The University of Colorado Health Sciences Center. She is board certified in both internal medicine and endocrinology.
Dr. Wyatt has been the National Program Director for the Centers for Obesity Research and Education (C.O.R.E) since 1998. C.O.R.E. was established to help educate health care professionals on how to manage obesity in their busy practices. CORE has educated over 5000 providers since its inception. Dr. Wyatt has received both a National Service Research Award and a Patient-Oriented Research Career Development Award (K23) from the National Institutes of Health to study energy metabolism and metabolic factors associated with weight loss in reduced-obese subjects. In 2004 Dr. Wyatt became senior editor of a new professional obesity journal- Obesity Management. She is also the medical director of a weight management program developed at The Center for Human Nutrition called The Colorado WeighTM.

Selected Publications

  • PW Sullivan, EH Morrato, V Ghushchyan, HR Wyatt, & JO Hill. Obesity, inactivity, and the prevalence of diabetes and diabetes-related cardiovascular comorbidities in the U.S., 2000-2002. Diabetes Care 2005; 28(7), 1599-1603. PUBMED

  • JO Hill & HR Wyatt. Role of physical activity in preventing and treating obesity. J Appl Physiol 2005, 99(2):765-770. PUBMED

  • HR Wyatt, JC Peters, GW Reed, GK Grunwald, M Barry JO Hill. A Colorado Statewide Survey of Walking and its Relation to Excessive Weight. Med Sci Sports Exer 2005; 37:724-30. PUBMED

  • James O. Hill, HR Wyatt, Suzanne Phelan, Rena Wing. The National Weight Control Registry:  Is it Useful in Helping Deal with our Obesity Epidemic? J Nutr Educ Behav 2005; 37:206-10.

  • HR Wyatt, JC Peters, GW Reed, GK. Grunwald, M Barry, H Thompson, J Jones, JO Hill. Using Electronic Step Counters To Increase Lifestyle Physical Activity: Colorado on the MoveTM. Journal of Physical Activity and Health 2004; 1:181-190.

  • WH Saris, SN Blair, MA van Baak, SB Eaton, PS Davies, L Di Pietro, M Fogelholm, A Rissnen, D Schoeller, B Swinburn, A Tremblay, KR Westerterp, HR Wyatt. How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock conference and consensus statement. Obesity Reviews 2003, 4(2):101-114.

  • GD Foster, HR Wyatt, JO Hill, BG McGuckin, C Brill, BS Mohammed, PO Szapary, DJ Rader, JS Edman, S Klein. A Multi-Center, Randomized, Controlled Trial of a Low-Carbohydrate Diet for Obesity. New England Journal of Medicine 2003; 348:2082-2090. PUBMED

  • JO Hill, HR Wyatt, GW Reed, JC Peters. Obesity and the Environment: Where do we go from Here? Science 2003;299:853-855. PUBMED