Tyler Lab University of Colorado Denver
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Selected Publications

Clarke P, Meintzer SM, Moffitt L, Tyler KL. Related Articles, Links

Two distinct phases of virus-induced NF-kappaB- regulation enhance TRAIL-mediated apoptosis in virus-infected cells.
J Biol Chem. 2003 Mar 13 [epub ahead of print]
PMID: 12637521 [PubMed - as supplied by publisher]
Richardson-Burns SM, Kleinschmidt-DeMasters BK, DeBiasi RL, Tyler KL. Related Articles, Links
Progressive multifocal leukoencephalopathy and apoptosis of infected oligodendrocytes in the central nervous system of patients with and without AIDS.
Arch Neurol. 2002 Dec;59(12):1930-6.
PMID: 12470182 [PubMed - indexed for MEDLINE]
DeBiasi RL, Kleinschmidt-DeMasters BK, Richardson-Burns S, Tyler KL. Related Articles, Links
Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis.
J Infect Dis. 2002 Dec 1;186(11):1547-57.
PMID: 12447729 [PubMed - indexed for MEDLINE]
Kominsky DJ, Bickel RJ, Tyler KL. Related Articles, Links
Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels.
J Virol. 2002 Nov;76(22):11414-24.
PMID: 12388702 [PubMed - indexed for MEDLINE]
Richardson-Burns SM, Kominsky DJ, Tyler KL. Related Articles, Links
Reovirus-induced neuronal apoptosis is mediated by caspase 3 and is associated with the activation of death receptors.
J Neurovirol. 2002 Oct;8(5):365-80.
PMID: 12402163 [PubMed - in process]
Kominsky DJ, Bickel RJ, Tyler KL. Related Articles, Links
Reovirus-induced apoptosis requires both death receptor- and mitochondrial-mediated caspase-dependent pathways of cell death.
Cell Death Differ. 2002 Sep;9(9):926-33.
PMID: 12181743 [PubMed - indexed for MEDLINE]
Poggioli GJ, DeBiasi RL, Bickel R, Jotte R, Spalding A, Johnson GL, Tyler KL. Related Articles, Links
Reovirus-induced alterations in gene expression related to cell cycle regulation.
J Virol. 2002 Mar;76(6):2585-94.
PMID: 11861824 [PubMed - indexed for MEDLINE]
Spalding AC, Jotte RM, Scheinman RI, Geraci MW, Clarke P, Tyler KL, Johnson GL. Related Articles, Links
TRAIL and inhibitors of apoptosis are opposing determinants for NF-kappaB-dependent, genotoxin-induced apoptosis of cancer cells.
Oncogene. 2002 Jan 10;21(2):260-71.
PMID: 11803469 [PubMed - indexed for MEDLINE]
Clarke P, Meintzer SM, Widmann C, Johnson GL, Tyler KL. Related Articles, Links
Reovirus infection activates JNK and the JNK-dependent transcription factor c-Jun.
J Virol. 2001 Dec;75(23):11275-83.
PMID: 11689607 [PubMed - indexed for MEDLINE]
Tyler KL, Clarke P, DeBiasi RL, Kominsky D, Poggioli GJ. Related Articles, Links
Reoviruses and the host cell.
Trends Microbiol. 2001 Nov;9(11):560-4. Review.
PMID: 11825717 [PubMed - indexed for MEDLINE]
Clarke P, Meintzer SM, Spalding AC, Johnson GL, Tyler KL. Related Articles, Links
Caspase 8-dependent sensitization of cancer cells to TRAIL-induced apoptosis following reovirus-infection.
Oncogene. 2001 Oct 18;20(47):6910-9.
PMID: 11687970 [PubMed - indexed for MEDLINE]
Poggioli GJ, Dermody TS, Tyler KL. Related Articles, Links
Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2).
J Virol. 2001 Aug;75(16):7429-34.
PMID: 11462015 [PubMed - indexed for MEDLINE]
DeBiasi RL, Edelstein CL, Sherry B, Tyler KL. Related Articles, Links
Calpain inhibition protects against virus-induced apoptotic myocardial injury.
J Virol. 2001 Jan;75(1):351-61.
PMID: 11119604 [PubMed - indexed for MEDLINE]
Poggioli GJ, Keefer C, Connolly JL, Dermody TS, Tyler KL. Related Articles, Links
Reovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis.
J Virol. 2000 Oct;74(20):9562-70.
PMID: 11000227 [PubMed - indexed for MEDLINE]
Clarke P, Meintzer SM, Gibson S, Widmann C, Garrington TP, Johnson GL, Tyler KL. Related Articles, Links
Reovirus-induced apoptosis is mediated by TRAIL.
J Virol. 2000 Sep;74(17):8135-9.
PMID: 10933724 [PubMed - indexed for MEDLINE]
Yujiri T, Ware M, Widmann C, Oyer R, Russell D, Chan E, Zaitsu Y, Clarke P, Tyler K, Oka Y, Fanger GR, Henson P, Johnson GL. Related Articles, Links
MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation.
Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7272-7.
PMID: 10852963 [PubMed - indexed for MEDLINE]
Connolly JL, Rodgers SE, Clarke P, Ballard DW, Kerr LD, Tyler KL, Dermody TS. Related Articles, Links
Reovirus-induced apoptosis requires activation of transcription factor NF-kappaB.
J Virol. 2000 Apr;74(7):2981-9.
PMID: 10708412 [PubMed - indexed for MEDLINE]
Debiasi RL, Squier MK, Pike B, Wynes M, Dermody TS, Cohen JJ, Tyler KL. Related Articles, Links
Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors.
J Virol. 1999 Jan;73(1):695-701.
PMID: 9847375 [PubMed - indexed for MEDLINE]
Tyler KL. Related Articles, Links
Pathogenesis of reovirus infections of the central nervous system.
Curr Top Microbiol Immunol. 1998;233 Reovir.ii:93-124. Review. No abstract available.
PMID: 9599934 [PubMed - indexed for MEDLINE]
Oberhaus SM, Dermody TS, Tyler KL. Related Articles, Links
Apoptosis and the cytopathic effects of reovirus.
Curr Top Microbiol Immunol. 1998;233 Reovir.ii:23-49. Review. No abstract available.
PMID: 9599930 [PubMed - indexed for MEDLINE]
Oberhaus SM, Smith RL, Clayton GH, Dermody TS, Tyler KL. Related Articles, Links
Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis.
J Virol. 1997 Mar;71(3):2100-6.
PMID: 9032342 [PubMed - indexed for MEDLINE]
Rodgers SE, Barton ES, Oberhaus SM, Pike B, Gibson CA, Tyler KL, Dermody TS. Related Articles, Links
Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2.
J Virol. 1997 Mar;71(3):2540-6.
PMID: 9032397 [PubMed - indexed for MEDLINE]
Tyler KL, Squier MK, Brown AL, Pike B, Willis D, Oberhaus SM, Dermody TS, Cohen JJ. Related Articles, Links
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes.
J Virol. 1996 Nov;70(11):7984-91.
PMID: 8892922 [PubMed - indexed for MEDLINE]
Tyler KL, Squier MK, Rodgers SE, Schneider BE, Oberhaus SM, Grdina TA, Cohen JJ, Dermody TS. Related Articles, Links
Differences in the capacity of reovirus strains to induce apoptosis are determined by the viral attachment protein sigma 1.
J Virol. 1995 Nov;69(11):6972-9.
PMID: 7474116 [PubMed - indexed for MEDLINE]
Virgin HW 4th, Tyler KL. Related Articles, Links
Role of immune cells in protection against and control of reovirus infection in neonatal mice.
J Virol. 1991 Oct;65(10):5157-64.
PMID: 1654436 [PubMed - indexed for MEDLINE]
Tyler KL, Virgin HW 4th, Bassel-Duby R, Fields BN. Related Articles, Links
Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system.
J Exp Med. 1989 Sep 1;170(3):887-900.
PMID: 2549167 [PubMed - indexed for MEDLINE]
Virgin HW 4th, Bassel-Duby R, Fields BN, Tyler KL. Related Articles, Links
Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing).
J Virol. 1988 Dec;62(12):4594-604.
PMID: 2460637 [PubMed - indexed for MEDLINE]
Bassel-Duby R, Spriggs DR, Tyler KL, Fields BN. Related Articles, Links
Identification of attenuating mutations on the reovirus type 3 S1 double-stranded RNA segment with a rapid sequencing technique.
J Virol. 1986 Oct;60(1):64-7.
PMID: 3528529 [PubMed - indexed for MEDLINE]
Tyler KL, McPhee DA, Fields BN. Related Articles, Links
Distinct pathways of viral spread in the host determined by reovirus S1 gene segment.
Science. 1986 Aug 15;233(4765):770-4.
PMID: 3016895 [PubMed - indexed for MEDLINE]
Kaye KM, Spriggs DR, Bassel-Duby R, Fields BN, Tyler KL. Related Articles, Links
Genetic basis for altered pathogenesis of an immune-selected antigenic variant of reovirus type 3 (Dearing).
J Virol. 1986 Jul;59(1):90-7.
PMID: 3012122 [PubMed - indexed for MEDLINE]

 

 
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