School of Dental Medicine Faculty

KRISTIN ARTINGER Assistant Professor Craniofacial Biology Mail Stop 8120, RC1-S, Rm L18 11100 12801 E. 17th Ave P.O. Box 6511 Aurora, CO 80045 Phone: 303-724-4562 Fax: 303-724-4580 Email: Click for Email

Education:
1991-1995 Ph.D., Developmental and Cell Biology, University of California, Irvine
Thesis Advisor: Dr. Marianne Bronner-Fraser
Dissertation Title: Dorsoventral Patterning of the Neural Tube and Neural Crest
1985-1989 B.S., Biological Sciences, University of California, Irvine

Honors and Awards:
Edward Steinhaus Memorial Award for Teaching, University of California, Irvine 1994-1995
Regents Dissertation Fellowship, University of California, Irvine, 1995
Schneiderman Graduate Research Award, University of California, Irvine, 1995
National Research Service Award, National Institutes of Health, 1997-2000
Charles A. King Trust, The Medical Foundation Postdoctoral Fellowship, 2000-2001
Scholar Development and Faculty Transition Award (K22), NIDCR/NIH, 2001-2006
Pew Biomedical Scholars Award, UCD nominee, 2004
Basil O’Conner Starter Award, March of Dimes, 2004- 2006
Society for Developmental Biology Junior Faculty Representative, 2004-2007
Keck Foundation Distinguished Young Scholar, UCD nominee, 2005

Departmental Affiliations:
Department of Cell and Developmental Biology, joint appointment, UCD
Department of Pediatrics, joint appointment, UCD
Department of Biology, affiliate member, CSU
Department of Ecology, Evolution and Population Biology, member graduate faculty, UCB
Member, University of Colorado Cancer Center, UCD

Research Interests:

1.Identification of novel genes involved in the specification, migration and differentiation of neural crest cells and Rohon-Beard sensory neurons in zebrafish.
2.How do the novel and existing genes that are involved in the specification of these cells fit into the molecular cascade? What is the role of specific transcription factors in this process?
3.What are the lineal relationships between cell types at the neural plate border? Do they require the same set of inductive cues? What are the molecular signals that induce them?

Recent Publications:

Cortez C, Hernandez-Lagunas A-L, Zhang C, Choi I, Kwok L and Artinger KB. Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis. Developmental Biology 2007; in revision.

Wenzlau JM, Garl PJ, Simpson P, Stenmark KR, West J ,Artinger KB, Nemenoff RA and Weiser-Evans MCM. Embryonic Growth Associated Protein is One Subunit of a Novel N-Terminal Acetyltransferase Complex Essential for Embryonic Vascular Development. Circulation Research 2006; 98(6), 846-55.

Hernandez-Lagunas L, Choi IF, Simpson P, Kaji T, Hershey C, Zhou Y, Zon L, Mercola M, and Artinger KB. Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Developmental Biology 2005; 278, 347-357

Kaji T and Artinger KB. dlx3b and dlx4b function in the formation of Rohon-Beard Sensory neurons and Trigminal plaocdes in the zebrafish neurula Developmental Biology 2004; 276(2),523-40

Zhang C, Basta T, Hernandez-Lagunas L, Simpson P, Stemple D, Artinger KB, Klymkowsky MW. Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish, Developmental Biology 2004; 273, 23-37.

Woda J, Pastagia J, Mercola M, Artinger KB. Dlx proteins position the neural plate border and determine adjacent cell fates. Development 2003; 130, 331-342

Cortez, C., Hernandez-Lagunas, A-L., Zhang, C., Choi, I., Kwok, L. and Artinger, K.B. (2008) Rohon-Beard sensory neurons are induced by BMP4 expressing non-neural ectoderm in Xenopus laevis. Developmental Biology, 314, 351-61.

Latest Publications in PubMed

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