• Agarwal, Rajesh, Ph.D.
• Anchordoquy, Thomas J., Ph.D.
• Anderson, Peter, Pharm.D.
• Aquilante, Christina, Pharm.D.
• Bain, David L., Ph.D.
• Carpenter, John, Ph.D.
• Franklin, Christopher, Ph.D.
• Hail, Jr., Numsen, Ph.D.
• Irons, Richard D., Ph.D.
• Jones Braun, LaToya, Ph.D.
• Ju, Cynthia, Ph.D.
• Kiser, Jennifer, Pharm.D.
• Kompella Uday B., PhD
• Malkinson, Alvin M., Ph.D.
• Mallela, Krishna M. G., Ph.D.
• Maluf, N. Karl, Ph.D.
• Patel, Manisha, Ph.D.
• Petersen, Dennis R., Ph.D.
• Radcliffe, Richard, Ph.D.
• Ross, David, Ph.D.
• Ruth, James. A., Ph.D.
• Scheinman, Robert I., Ph.D.
• Thompson, John A., Ph.D.
• Vasiliou, Vasilis, Ph.D.

LaToya S. Jones Braun, Ph.D.

Assistant Professor, Department of Pharmaceutical Sciences

Mailing address:
4200 E. 9th Ave, C238
Denver, CO 80262

Telephone:
Voice:     303-315-0197
Lab:        303-315-0211
Fax:        303-315-6281
E-mail:  Latoya.JonesBraun@uchsc.edu

Affiliations:
American Association of Pharmaceutical Scientists
American Society for Biochemistry and Molecular Biology
Center for Pharmaceutical Biotechnology
Society for the Advancement of Chicanos and Native Americans in Science

Training and Education:
Ph.D., University of Colorado Denver (Pharmaceutical Sciences)
M.S., University of Colorado at Boulder (Chemical Engineering)
B.S., Yale University (Chemical Engineering)

Clinical/Research Interests:
The current research focus of the lab is directed towards understanding the interactions between vaccine antigens and adjuvants.  We are interested in these interactions from two perspectives:  (1) developing stable vaccine formulations and (2) understanding mechanisms by which adjuvants enhance the immune system’s response to vaccine antigens. We use a variety of biophysical techniques (i.e., spectroscopy, calorimetry, etc.) to address these questions.

Teaching:
Professional Program:
PHRD 3610 Science Foundations II: Biochemistry and Cell Function
Graduate Program:
PHSC 7350 Protein Chemistry I
PHSC 7568 Seminar in Pharmaceutical Sciences
PHSC 7330 Issues in Drug Development

Recent Publications:
Peek, L.J., Brandau, D.T., Jones, L.S., Joshi, S.B. and Middaugh, C.R.  A systematic approach to stabilizing EBA-175 RII-NG for use as a malaria vaccine.  Vaccine 2006 24 5839-5851.
Dong, A., Jones, L.S., Kerwin, B.A., Krishnan, S. and Carpenter, J.F.  Secondary structures of proteins adsorbed onto aluminum hydroxide: infrared spectroscopic analysis of proteins from low solution concentrations. Anal Biochem., 2006 351 282-9.
Jones, L.S.*, Peek, L.J.*, Power, J., Markham, A., Yazzie, B. and Middaugh, C.R.  Effects of Adsorption to Aluminum Salt Adjuvants on the Structure and Stability of Model Protein Antigens.  JBC, 2005 280 13406-13414.
Jones. L.S., Kaufmann, A.M., and Middaugh , C.R. Silicone oil induced aggregation of proteins.  J.Pharm. Sci., 2005 94 918-927.
Jones, L.S., Yazzie, B., and Middaugh, C.R. Polyanions and the proteome. Molecular and Cellular Proteomics. 2004 3 746-769. 

Keywords: vaccines, antigen/adjuvant interactions, antigen structure, vaccine stability

Curriculum Vitae
Recent Publications

Last updated: 6/16/08