• Ph.D. in Pharmaceutical Sciences
• Program Requirements
• Core Curriculum
• Program Faculty
• Certificate in Pharmaceutical Biotechnology
• Center for Pharmaceutical Biotechnology
• Application Information
• FAQs
• Ph.D. in Toxicology
• Program Requirements
• Core Curriculum
• Program Faculty
• Research Areas
• Program Graduate Students
• Program Graduates
• Pharmaceutical Outcomes Research [Area of Emphasis within the Pharmaceutical Sciences Ph.D. Program]
• Requirements
• Faculty
• Contact Information
• Application Information

The following is a description of the core curriculum (basic science component) for the Ph.D. graduate program in Pharmaceutical Sciences at the University of Colorado School of Pharmacy.

REQUIRED COURSES

PHSC 7310 Fundamentals of Pharmaceutical Sciences – 3 credits
    • Biophysical Approaches
    • Pharmaceutics/Formulation 101
    • Topics in Cell Biology
    • Pharmacokinetics 
    • Pharmacogenomics
    • Basic Immunology

PHSC 7350 Protein Chemistry – 3 credits  
    • Protein Structure
    • Protein Stability
    • Basic Enzymology
    • Protein Folding
    • Protein Thermodynamics

TXCL 7562 Analytical Basis of Forensic Toxicology – 2 credits
    • Chromatographic Theory
    • Chromatographic Practice: GC/HPLC/TLC 
    • Basics of Immunoassays 
    • Principles of Mass Spectrometry 
    • Blood/Breath Ethanol Measurement 
    • Application of all of the above to 
        legal quantitation, pharmacokinetics, and effects of ethanol/cocaine/THC/amphetamines

PHSC 7652 Principles of Medicinal Chemistry – 2 credits
    • Fundamentals of Structure-Activity Relationships (SAR) 
    • Mechanisms of Drug Action • Rational Drug Design 
    • Structure Effects of Drug Disposition 
    • SAR of Various Therapeutic Classes of Drugs 

Other science courses commonly taken by our students include: 

• PHSC 7330 Issues in Drug Development – 2 credits
• PHSC 7325 Pharmaceutical Development: Evaluating the External Environment – 2 credits
• PHSC 7345 Principles of Drug Delivery – 2 credits
• PHSC 7354 Structural Analysis of Biomolecules I – 2 credits
• PHSC 7454 Structural Analysis of Biomolecules II – 2 credits
• PHSC 7530 Cancer: Experimental and Medical Aspects- 2 credits
• PHSC 7561 Pharmacology of Anti-Cancer Agents – 2 credits
• PHSC 7649 Introduction to Modern Biotechnology – 1 credit
• PHSC 7651/CHEN 5810 Pharmaceutical Biotechnology – 3 credits 
• PHSC 7653 Protein Formulation – 2 credits
• PHSC 7660 Membrane Dynamics – 2 credits
• PHSC 7831 Case Studies in Biotechnology – 2 credits
• TXCL 7560 Drug Metabolism & Pharmacogenetics I – 3 credits
• TXCL 7561 Drug Metabolism & Pharmacogenetics II – 3 credits

PLEASE NOTE THAT SOME REQUIRED COURSES IN THE PHARMACEUTICAL SCIENCES ARE TAUGHT EVERY OTHER YEAR. THE CURRENT SCHEDULE FOR THESE COURSES IS GIVEN BELOW.

Planned Course Schedule for Pharmaceutical Sciences Courses: 

2008-2009
·  Fall – Analytical Basis of Forensic Toxicology; Fundamentals of Pharmaceutical Sciences; Drug Metabolism and Pharmacogenetics I; Ethical Issues in Toxicology and Pharmaceutical Sciences
· Spring – Protein Chemistry; Protein Formulation; Cancer: Experimental and Medical Aspects; Drug Metabolism and Pharmacogenetics II; Case Studies in Biotechnology; Principles of Drug Delivery

2009-2010
· Fall – Principles of Medicinal Chemistry; Pharmaceutical Biotechnology; Introduction to Modern Biotechnology Fundamentals of Pharmaceutical Sciences; Ethical Issues in Toxicology and Pharmaceutical Sciences
· Spring –  Membrane Dynamics; Structural Analysis of Biomolecules I + II; Issues in Drug Development

OTHER REQUIREMENTS: In addition, our students must complete: