Research Areas
Molecular Toxicology and Environmental Health Science
CancerClinical and Forensic Toxicology
Hepatotoxicology
Immunotoxicology
Neurotoxicology
Pharmacogenetics
Pharmacogenomics
Pulmonary Toxicology
Cancer
Faculty Member | Research Interests |
| Rajesh Agarwal | Cancer chemoprevention, phytochemicals, mitogenic signaling, cell-survival signaling, apoptosis, cell cycle |
| Dennis Ahnen | Colon cancer, chemoprevention, molecular biology, molecular epidemiology,Non-steroidal anti-inflammatory drugs, signal transduction |
| Thomas Anchordoquy | |
| James Crapo | |
| Marc Fariss | Oxidative stress, antioxidants, mitochondria, cancer, Parkinson's disease, iron-overload liver disease |
| Christopher Franklin | Apoptosis, glutathione, oxidative stress, arsenic, gene expression, signal transduction, protein kinases, protein phosphatases |
| Brian Freed | Cigarette smoking, pulmonary, T cell function, acrolein, hydroquinone, catechol |
| Dan Gustafson | Cancer, chemotherapy, chemoprevention, molecularly targeted agents, cytotoxic agents, angiogenesis, pharmacokinetics, pharmacodynamics, enzymology |
| Richard Irons | Hematoxicity, immunotoxicity, leukemia, lymphoma, alkylating chemotherapeutic agents, human hepatopoietic cells, mechanistic toxicology, benzene poisoning,epidemiology, disease progression, metabolism, Epstein Barr virus |
| Al Malkinson | |
| Joe McCord | Free radicals, superoxide, superoxide dismutase, cancer, diabetes, oxidative stress |
| Robert Murphy | Mass spectrometry, lipid mediators, eicosanoids |
| Lawrence Ng | |
| Linda Quattrochi | Molecular toxicology; cytochrome P450 regulation; dioxin toxicity; chemoprevention; viral hepatitis; human/cells |
| David Ross | Molecular toxicology, anticancer drug development, quinone reductases, NQO1, quinones, pharmacogenetics, benzene, dopamine, proteasomal inhibition |
| Robert Scheinman | Gene regulation, transcription, NF-kappa B, immunology, T cell, autoimmunity |
| David Siegel | Drug metabolism, quinone metabolism, quinone bioactivation, quinone reductase, pharmacogenetics, oxidative stress, superoxide scavenging, cancer pharmacology |
| Kathleen Stringer | Inflammation, neutrophils, apoptosis, NADPH oxidase |
| John Thompson | Drug metabolism, chemical toxicology, carcinogenesis, chemoprevention, antioxidants, mass spectrometry |
| Vasilis Vasiliou | Cellular responses to oxidative stress, ethanol/acetaldehyde metabolism, aldehyde dehydrogenases, pharmacogenetics, humans/animals/cells, transgenic mice |
Clinical and Forensic Toxicology
|
Faculty Member | Research Interests |
| Gregory Bogdan | Acetaminophen, antidote development, animal venoms, cyanide, terrorism & disaster response, arsenic and lead |
| Richard Dart | Acetaminophen (paracetamol), acetylcysteine, alcohol abuse, snake venom, black widow spider, terrorism, chemical warfare, opioid dependence, opioid addiction |
| Phillip Guzelian | Cytochrome P450, hepatocyte culture, signal Transduction, receptor mediated induction, gene expression, steriod hormones |
| James Ruth | Forensic Toxicology |
Hepatotoxicology
|
Faculty Member | Research Interests |
| Lawrence Berliner | Free radicals, in vivo EPR, ESR, spin traps, nitric oxide, superoxide, superoxide scavenging, molecular toxicology, drug metabolism, oxidative stress, antioxidants, protein structure and folding |
| Gregory Bogdan | Acetaminophen, antidote development, animal venoms, cyanide, terrorism & disaster response, arsenic and lead |
| Richard Dart | Acetaminophen (paracetamol), acetylcysteine, alcohol abuse, snake venom, black widow spider, terrorism, chemical warfare, opioid dependence, opioid addiction |
| Marc Fariss | Oxidative stress, antioxidants, mitochondria, cancer, ParkinsonŐs disease, iron-overload liver disease |
| Christopher Franklin | Apoptosis, glutathione, oxidative stress, arsenic,gene expression, signal transduction, protein kinases, protein phosphatases |
| Phillip Guzelian | Cytochrome P450, hepatocyte culture, signal Transduction, receptor mediated induction, gene expression, steriod hormones |
| Cynthia Ju | Hepatic macrophages (Kupffer cells, KC), KC-mediated immunological tolerance, drug-induced immune- and non-immune-mediated liver injury, hepatic inflammation, animal/cells, transgenic mice |
| Dennis Petersen | |
| Linda Quattrochi | Molecular toxicology; cytochrome P450 regulation; dioxin toxicity; chemoprevention; viral hepatitis; human/cells |
| Vasilis Vasiliou | Cellular responses to oxidative stress, ethanol/acetaldehyde metabolism, aldehyde dehydrogenases, pharmacogenetics, humans/animals/cells, transgenic mice |
Immunotoxicology
|
Faculty Member | Research Interests |
| Sonia Flores | Inflammation and oxidant-stress mediated vascular complications in Type 1 diabetes, autoimmunity and NADPH-oxidase-mediated vascular dysfunction |
| Brian Freed | Cigarette smoking, pulmonary, T cell function, acrolein, hydroquinone, catechol |
| Richard Irons | Hematoxicity, immunotoxicity, leukemia, lymphoma, alkylating chemotherapeutic agents, human hepatopoietic cells, mechanistic toxicology, benzene poisoning, epidemiology, disease progression, metabolism, Epstein Barr virus |
| Cynthia Ju | Hepatic macrophages (Kupffer cells, KC), KC-mediated immunological tolerance, drug-induced immune- and non-immune-mediated liver injury, hepatic inflammation, animal/cells, transgenic mice |
| Robert Scheinman | Gene regulation, transcription, NF-kappa B, immunology, T cell, autoimmunity |
Neurotoxicology
|
Faculty Member | Research Interests |
| Lawrence Berliner | Free radicals, in vivo EPR, ESR, spin traps, nitric oxide, superoxide, superoxide scavenging, molecular toxicology, drug metabolism, oxidative stress, antioxidants, protein structure and folding |
| Marc Fariss | Oxidative stress, antioxidants, mitochondria, cancer, ParkinsonŐs disease, iron-overload liver disease |
| Lawrence Ng | |
| Manisha Patel | Neuroscience, oxidative stress, mitochondria, epilepsy, excitotoxicity, neurodegeneration, neurotoxicology |
| Richard Radcliffe | Neuroscience, neurotoxicology, alcoholism, alcohol tolerance, model organisms, drug abuse, molecular genetics, behavior genetics, gene expression microarrays, QTL mapping |
| David Ross | Molecular toxicology, anticancer drug development, quinone reductases, NQO1, quinones, pharmacogenetics, benzene, dopamine, proteasomal inhibition |
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Pharmacogenetics
|
Faculty Member | Research Interests |
| Peter Anderson | Antiretroviral drug therapy; HIV; Antiviral drug therapy; pharmacokinetics; pharmacodynamics |
| Dan Gustafson | Cancer, chemotherapy, chemoprevention, molecularly targeted agents, cytotoxic agents, angiogenesis, pharmacokinetics, pharmacodynamics, enzymology |
| Phillip Guzelian | Cytochrome P450, hepatocyte culture, signal Transduction, receptor mediated induction, gene expression, steriod hormones |
| Richard Irons | Hematoxicity, immunotoxicity, leukemia, lymphoma, alkylating chemotherapeutic agents, human hepatopoietic cells, mechanistic toxicology, benzene poisoning, epidemiology, disease progression, metabolism, Epstein Barr virus |
| Robert Murphy | Mass spectrometry, lipid mediators, eicosanoids |
| Dennis Petersen | |
| Linda Quattrochi | Molecular toxicology; cytochrome P450 regulation; dioxin toxicity; chemoprevention; human/cells |
| David Ross | Molecular toxicology, anticancer drug development, quinone reductases, NQO1, quinones, pharmacogenetics, benzene, dopamine, proteasomal inhibition |
| David Siegel | Drug metabolism, quinone metabolism, quinone bioactivation, quinone reductase, pharmacogenetics, oxidative stress, superoxide scavenging, cancer pharmacology |
| John Thompson | Drug metabolism, chemical toxicology, carcinogenesis, chemoprevention, antioxidants, mass spectrometry |
| Vasilis Vasiliou | Cellular responses to oxidative stress, ethanol/acetaldehyde metabolism, aldehyde dehydrogenases, pharmacogenetics, humans/animals/cells, transgenic mice |
Pharmacogenomics
|
Faculty Member | Research Interests |
| James Crapo | |
| Phillip Guzelian | Cytochrome P450, hepatocyte culture, signal Transduction, receptor mediated induction, gene expression, steriod hormones |
| Dennis Petersen | |
| Richard Radcliffe | Neuroscience, neurotoxicology, alcoholism, alcohol tolerance, mice/zebrafish, drug abuse, genetics, microarrays, QTL mapping, fear conditioning |
| David Ross | Molecular toxicology, anticancer drug development, quinone reductases, NQO1, quinones, pharmacogenetics, benzene, dopamine, proteasomal inhibition |
| David Siegel | Drug metabolism, quinone metabolism, quinone bioactivation, quinone reductase, pharmacogenetics, oxidative stress, superoxide scavenging, cancer pharmacology |
| Vasilis Vasiliou | Cellular responses to oxidative stress, ethanol/acetaldehyde metabolism, aldehyde dehydrogenases, pharmacogenetics, humans/animals/cells, transgenic mice |
Pulmonary Toxicology
|
Faculty Member | Research Interests |
| Lawrence Berliner | Free radicals, in vivo EPR, ESR, spin traps, nitric oxide, superoxide, superoxide scavenging, molecular toxicology, drug metabolism, oxidative stress, antioxidants, protein structure and folding |
| James Crapo | |
| Brian Day | |
| Sonia Flores | HIV Tat protein-mediated lung oxidant stress, superoxide dismutase regulation, oxidant-mediated regulation of gene expression |
| Al Malkinson | Genetic analysis of mouse lung tumor formation, role of inflammation in lung neoplasia, chemoprevention |
| Joe McCord | Free radicals, superoxide, superoxide dismutase, cancer, diabetes, oxidative stress |
| Carl White | Role of oxidation-reduction status in lung health and disease.Oxidant-antioxidant balance in acute and chronic lung injury. Signal transduction in pulmonary endothelial and epithelial cells |
Last updated: 7/05/07