Research Objectives:

The overall goal of our research effort is to examine the potential of cell replacement therapies for brain repair in neurodegeneration (Parkinson’s disease) and for modification of neural networks that control drug dependence (Alcohol). Our secondary goal is to determine which molecules mediate neurodegeneration and how we can use this information to restore normal brain function and protect neurons from degenerating. Currently ongoing projects are listed below:

 W. Michael Zawada Ph.D.
   
  • Neurotransplantation of dopamine neurons and stem cells in animal models of Parkinson's disease
  • Transplantation of genetically modified stem cells for moderation of drug dependence
  • Examination of cell signaling pathways involved in neuronal death
  • Identification of specific molecular targets useful for neuroprotection
  • Developing methods for stem cell differentiation into neural cells

University of Colorado Denver
Division of Clinical Pharmacology, C-237

4200 E. 9th Ave. Denver , CO , 80262
(303) 315-8455 or (303) 315-8488